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This new edition of The American Psychiatric Association Publishing Textbook of Mood Disorders is a systematic and painstaking reconceptualization of its predecessor. Under new editorial direction and with a revised roster of expert contributors, the second edition is an utterly current, clinically competent, and comprehensive text that will become an instant classic. The book is structured for learning and easy reference, moving deftly from symptomatology and epidemiology to pathogenesis and on to somatic interventions, cognitive-behavioral interventions, and psychotherapy. The latest science on genetics and epigenetics, brain imaging, and neurobiology are also examined in depth. Critically important to the clinician is the section on management of mood disorders, which provides treatment guidelines for major depressive disorder and bipolar disorder, as well as information on understanding, and preventing, suicide in children, adolescents, and adults. Finally, perspectives are offered on depression among women, children, and geriatric patients, as well as on depression across cultures. Practicing psychiatrists, residents, and students alike will benefit from the book's inclusive coverage.Topics new to this edition include the following: • Treatment-resistant depression—its definition and approaches to its treatment—is addressed in a dedicated chapter that covers diagnostic accuracy, pseudoresistance, comorbidity, pharmacological management, adjunctive strategies, psychotherapy, neuromodulation, and novel and experimental therapies.• Investigational agents, most notably ketamine and its relatives, constitute an exciting frontier in the treatment of mood disorders, and the clinical application, routes of delivery, dosing, risks, and clinical trials are explored in a dedicated chapter that is both rigorous and thorough.• There is compelling evidence that childhood maltreatment (defined as exposure to emotional, physical, and sexual abuse and neglect before the age of 18 years) is a prominent risk factor for the development of mood disorders as well as for a pernicious course and poor treatment response in mood disorders. These findings, as well as the underlying neurobiological and environmental interactions that may contribute to the development of mood disorders, are examined thoroughly and thoughtfully.• As our understanding of immune function in mood disorders has grown, psychoneuroimmunology has emerged as a focus of study likely to make major contributions to clinical practice in the coming decades. The book updates readers on this promising area of research. Over the last decade, depression has emerged as the leading cause of disability worldwide, with significant attendant morbidity and mortality. The American Psychiatric Association Publishing Textbook of Mood Disorders equips clinicians and trainees with the knowledge they need to alleviate suffering in their patients with mood disorders.

A collection of essays, framed with original introductions, Reproduction and Society: Interdisciplinary Readings helps students to think critically about reproduction as a social phenomenon. Divided into six rich and varied sections, this book offers students and instructors a broad overview of the social meanings of reproduction and offers opportunities to explore significant questions of how resources are allocated, individuals are regulated, and how very much is at stake as people and communities aim to determine their own family size and reproductive experiences. This is an ideal core text for courses on reproduction, sexuality, gender, the family, and public health.

This best-selling emergency department reference is now in its thoroughly updated Fifth Edition. The foremost authorities provide practical information on over 600 clinical problems in a fast-access two-page outline format that's perfect for on-the-spot consultation during care in the emergency department. Coverage of each disorder includes clinical presentation, pre-hospital, diagnosis, treatment, disposition, and ICD-9 coding. Icons enable practitioners to quickly spot the information they need. This edition provides up-to-date information on topics such as emerging infections, new protocols, and new treatments.

The present volume contains the scientific contributions to the Fifth International Symposium on'Current Trends in Sphingo­ lipidoses and Allied Disorders'under the auspices of the Isaac Albert Research Institute of the Kingsbrook Jewish Medical Center, the Department of Pathology, Downstate Medical Center, State Uni­ versity of New York, Brooklyn, New York, and the National Tay-Sachs and Allied Diseases Association, Inc., New York. A review of the four previous Symposia shows the increase in scope of the scientific exploration in this rapidly expanding field. The first meeting, held in 1958, was devoted to the discussion al­ most entirely of Tay-Sachs disease. The majority of the work emanated from local laboratories. The participants at the present Symposium came from many other domestic and foreign research in­ stitutions. The scope of the papers presented at these meetings and the interest shown in the Symposium demonstrates the signifi­ cance attached by the scientific community to the problems of these hereditary diseases. The reasons for this are apparent, when one considers the contributions during recent years to our basic know­ ledge by lipid and enzyme chemistry, genetics, and neuropathology. Partly because of the hereditary nature of these diseases any new discovery in this field has general meaning and permits cautious generalization well beyond its clinical significance.

We shall not, and those who come after us must not, accept the goals that were not reached yesterday as unsurmountable today or tomorrow. We will strive to render the world of the paralyzed-on-wheels but a transitory stop, and settle for nothing short of optimal recovery. N. Eric Naftchi In man, the process of'encephalization'culminates in almost complete control of the brain over the lower centers. Transection of the spinal cord severs the extensions of its nerve fiber tracts running to and from various brain centers. Although there is some confusion on the meaning of spinal shock, it is supposed to last from two to three weeks or longer in man, compared with less than a few minutes in the frog. This is a testimony to the complexity of the suprasegmental control in higher animals. Since the brain exerts its control over the internal environment through several monoamine, amino acids, and peptide neurotransmitters, it should not be surprising if the metabolism of these transmitters is found to be drastically altered along with other physical and metabolic dysfunctions which ensue following the spinal cord section. In spite of the major strides in rehabilitation of traumatic spinal cord injury, our knowledge of the etiology underlying the diverse neurophysiologic derangements remains limited. For instance, we are just becoming aware of some of the changes in the'milieu interieur.

An indispensable resource for K-12 educators and autism specialists, this highly practical book shows how to include students with autism spectrum disorders (ASD) in general education settings. Tristram Smith and his associates present a research-based, step-by-step process for assessing students at a range of skill levels, planning and implementing successful inclusion programs, and working as a team with other professionals and with parents. The book is packed with specific strategies for helping students with ASD follow the daily routine, learn from the general education curriculum, interact with peers, and overcome problem behavior. In a large-size format for easy photocopying, it features dozens of reproducible worksheets and forms.

The most recent advances in human identification are thoroughly discussed in this important new text. The twenty-five contributions to this volume demonstrate movement beyond the boundaries of forensic anthropology of only a decade ago. In Chapter 2 the role of the forensic anthropologist at scenes containing human victims, including multiple fatality incidents, fires, and serial murder investigations, is discussed. In Chapter 3, the role of the forensic anthropologist is examined in a unique type of recovery situation: death investigative work involving human rights violations. Chapter 4 discusses the cremation process and how it impacts the forensic anthropologist's role in analyzing remains. In Chapter 5, postmortem interval is discussed as well as the factors affecting decomposition, and the author provides a practical overview of recent techniques in determining time since death. Chapters 6 and 7 also discuss postmortem interval related to outdoor death scenes and assessment of time since death under markedly different environmental conditions. In Chapter 8, an overview of the morphological and metric metric approaches to sex estimations from skeletal remains is provided. Other chapters in this part discuss the criteria for sex and age determination of feral and neonatal material, as well as the Suchey-Brooks method and the pubic aging system. Other chapters in the book discuss the following topics: The Application of Histological Techniques for Age at Death Determination; A Multimedia Tool for the Assessment of Age in Immature Remains: The Electronic Encyclopedia for Maxillo-facial, Dental and Skeletal Development; Regression Formulae for Estimating Age at Death from Cranial Suture Closure; Craniofacial Criteria in the Skeletal Attribution of Race; The Timing of Injuries and Manner of Death; Recognizing Gunshot and Blunt Cranial Trauma Through Fracture Interpretation; Postmortem Dismemberment; Saw Marks in the Bones; Statistical Interpretation in Forensic Anthropology; The Forensic Data Bank; Technical Aspects of Identification of Skeletal Markers of Occupational Stress; Facial Approximation; The Evolving Role of the Microscope in Forensic Anthropology; and The Third Exhumation of Jesse Woodson James.