1. Acute necrotizing encephalopathy in an infant: A case report
- Author
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Elisamia Ngowi, Zeenat Juneja, Jacqueline Gabone, Maria Bulimba, Mohamedraza Ebrahim, and Yaser Abdallah
- Subjects
Acute necrotizing encephalopathy ,Case report ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Abstract
Acute necrotizing encephalopathy is a rare, severe neurological condition, characterized by symmetrical necrotic brain lesions affecting the thalamus, cerebral white matter, brain stem, and cerebellum. Diagnosis relies on characteristic clinical and radiological features. We describe a 10-month-old female infant presenting with multiple seizures following a brief febrile upper respiratory illness. MRI of the brain showed bilateral symmetrical abnormal signal intensities involving both thalami and caudate nucleus, consistent with ANE. Management of ANE is symptom-related but high-dose steroids and IVIG have been used. This case highlights the importance of recognizing ANE beyond its usual geographic distribution. Early recognition and prompt management help improve outcomes.
- Published
- 2025
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