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2-Ferrocenyl­carbonyl­benzoic acid (C18H14FeO3) was synthesized from the Friedel–Crafts acyl­ation of ferrocene with phthalic anhydride, and the product was reduced to 3-ferrocenylphthalide (C18H14FeO2) using Zn(Cu) in aqueous sodium hydroxide. Both compounds were characterized using IR, NMR, and single-crystal X-ray analysis., The title compounds, 2-(ferrocenylcarbon­yl)benzoic acid, [Fe(C5H5)(C13H9O3)], 1, and 3-ferrocenylphthalide [systematic name: 3-ferrocenyl-2-benzo­furan-1(3H)-one], [Fe(C5H5)(C13H9O2)], 2, have been synthesized and structurally characterized by single-crystal X-ray diffraction. The crystal structure of compound 1 was solved recently at room temperature [Qin, Y. (2019 ▸). CSD Communication (CCDC deposition number 1912662). CCDC, Cambridge, England]. Here we report a redetermination of its crystal structure at 90 K with improved precision by a factor of about three. The mol­ecular structures of both compounds exhibit a typical sandwich structure. In the crystal packing of compound 1, each mol­ecule engages in inter­molecular hydrogen bonding, forming a centrosymmetric dimer with graph-set notation R 2 2 (8) and an O⋯O distance of 2.6073 (15) Å. There are weak C—H⋯O and C—H⋯π inter­actions in the crystal packing of compound 2. The phthalide moiety in 2 is oriented roughly perpendicular to the ferrocene backbone, with a dihedral angle of 77.4 (2)°.

Assessing variation in animal coloration is difficult, as animals differ in their visual system properties. This has led some to propose that human vision can never be used to evaluate coloration, yet many studies have a long history of relying on human vision. To reconcile these views, we compared the reflectance spectra of preserved avian plumage elements with two measures that are human biased: RGB values from digital photographs and the corresponding reflectance spectra from a field guide. We measured 73 plumage elements across 14 bird species. The field guide reflectance spectra were drastically different from that of the actual birds, particularly for blue elements. However, principal component analyses on all three data sets indicated remarkably similar data structure. We conclude that human vision can detect much of the variation in coloration in the visible range, providing fodder for subsequent studies in ecology, evolution, behavior, and visual ecology.

Aims: Chronic diseases impose a substantial healthcare burden. This study sought to evaluate the clinical and economic impact of new disease management (DM) programs, targeting four major chronic d...

Canada’s National Forest Inventory (NFI) sampling program is designed to support reporting on forests at the national scale. On the other hand, continuous maps of forest attributes are required to support strategic analyses of regional policy and management issues. We have therefore produced maps covering 4.03 × 106 km2 of inventoried forest area for the 2001 base year using standardised observations from the NFI photo plots (PP) as reference data. We used the k nearest neighbours (kNN) method with 26 geospatial data layers including MODIS spectral data and climatic and topographic variables to produce maps of 127 forest attributes at a 250 × 250 m resolution. The stand-level attributes include land cover, structure, and tree species relative abundance. In this article, we report only on total live aboveground tree biomass, with all other attributes covered in the supplementary data ( http://nrcresearchpress.com/doi/suppl/10.1139/cjfr-2013-0401 ). In general, deviations in predicted pixel-level values from those in a PP validation set are greater in mountainous regions and in areas with either low biomass or sparse PP sampling. Predicted pixel-level values are overestimated at small observed values and underestimated at large ones. Accuracy measures are improved through the spatial aggregation of pixels to 1 km2 and beyond. Overall, these new products provide unique baseline information for strategic-level analyses of forests ( https://nfi.nfis.org ).

The objective of this study was to determine whether the protein Zhangfei could suppress the unfolded protein response (UPR) and growth of osteosarcoma cells. Dog (D-17) and a human (Saos-2) osteosarcoma cells were infected with adenovirus vectors expressing either Zhangfei or the control protein beta- galactosidase. We monitored cell growth as well as levels of UPR gene transcripts and proteins. We found that Zhangfei suppressed the growth of both D-17 and Saos-2 cells. Zhangfei-expressing D-17 cells displayed large vacuoles containing culture medium and expressed phosphatidylserine on their external surface suggesting that Zhangfei induced macropinocytosis and apoptosis in these cells. While Zhangfei inhibited the growth of both D-17 and Saos-2 cells, it inhibited thapsigargin-induced UPR, as detected by a decrease in transcripts for UPR genes, and HERP and GRP78 proteins, only in D-17 cells, suggesting that the ability of Zhangfei to suppress the UPR and tumour cells growth may not be linked.

As the number of operational wind scatterometers is getting smaller, other sources of spaceborne sensors are now included in global wind mapping. One of the prominent sensors is the Synthetic Aperture Radar (SAR). Besides serving as a generic scatterometer, SAR systems are the only type of radar systems that can provide sub-km resolution sea surface wind data and offers near shore mapping capability. This unique feature is important for assessing the offshore wind resources. As an important source of renewable energy, offshore wind farms are growing rapidly. Furthermore, recent research shows that the cross-polarization radar backscatter does not seem to saturate in high winds, and provides an excellent supplement for scatterometer wind sensing in storm conditions. The saturation issues of co-polarization radar returns have so far made it difficult to resolve wind speeds beyond roughly 20 m/s, or even less for lower incidence angles. The scope of this paper is to show the potential of RADARSAT-2's polarimetric modes for wind speed retrieval. RADARSAT-2 is the first operational fully polarimetric (HH VV HV VH) C-band satellite. Standard Quad-pol images have been collected in the St. Lawrence Gulf and compared against the Mont-Louis buoy and QuikSCAT scatterometer data. Co-polarization wind speeds were computed with CMOD-5 algorithms. A few polarization ratios were tested to determine the most suitable one for RADARSAT-2's HH polarization mode. For Cross-polarization, two different models were compared. Cross-polarization gives excellent results when wind exceeds 5 m/s. In general, SAR wind retrieval is suitable for resolution of 400 m.

Resume Objectif. – Examiner un syndrome qui peut se rencontrer au Canada et qui est assez mal connu dans la litterature francophone. Le Koro est un trouble psychiatrique habituellement decrit comme un syndrome specifique a certaines cultures asiatiques, se manifestant par une anxiete intense associee a la crainte d'une retraction du penis dans l'abdomen qui peut mener a la mort. Meme si quelques cas ont ete rapportes chez des sujets non asiatiques, le trouble est generalement decrit comme un syndrome specifiquement culturel. Methode. – Revue de litterature classique et description de cas ; les auteurs font une description de cas de Koro rencontres dans leur pratique clinique et ouvrent une discussion sur des aspects cliniques, epidemiologiques et etiologiques de ce syndrome. Resultats. – Il semble qu'une distinction doit etre faite entre les presentations epidemiques de Koro qui sont culturellement specifiques et les cas isoles qui peuvent apparaitre dans toute culture.

The objective of this study was to determine whether the protein Zhangfei could suppress the unfolded protein response (UPR) and growth of osteosarcoma cells. Dog (D-17) and a human (Saos-2) osteosarcoma cells were infected with adenovirus vectors expressing either Zhangfei or the control protein beta- galactosidase. We monitored cell growth as well as levels of UPR gene transcripts and proteins. We found that Zhangfei suppressed the growth of both D-17 and Saos-2 cells. Zhangfei-expressing D-17 cells displayed large vacuoles containing culture medium and expressed phosphatidylserine on their external surface suggesting that Zhangfei induced macropinocytosis and apoptosis in these cells. While Zhangfei inhibited the growth of both D-17 and Saos-2 cells, it inhibited thapsigargin-induced UPR, as detected by a decrease in transcripts for UPR genes, and HERP and GRP78 proteins, only in D-17 cells, suggesting that the ability of Zhangfei to suppress the UPR and tumour cells growth may not be linked.