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1. Behavioural outcomes of subthalamic stimulation and medical therapy versus medical therapy alone for Parkinson's disease with early motor complications (EARLYSTIM trial): secondary analysis of an open-label randomised trial

Author

Negovanska, Velina, Welter, Marie-Laure, Corvol, Jean-Christophe, Agid, Yves, Navarro, Soledad, Meier, Niklaus, Hartmann, Andreas, Hesekamp, Helke, Cornu, Philippe, Möller, Bettina, Nebel, Adelheid, Raethjen, Jan, Knudsen, Karina, Volkmann, Jens, Falk, Daniela, Paschen, Steffen, Meister, Ingo, Kuhn, Jens, Donner, Kerstin, Kessler, Josef, Barbe, Michael, Fink, Gereon, Maarouf, Mohammad, Kühn, Andrea, Müller, Bianca, Faust, Katharina, Gruber, Doreen, Schneider, Gerd-H., Seigneuret, Eric, Pollak, Pierre, Fraix, Valerie, Kistner, Andrea, Rascol, Olivier, Arbus, Christophe, Danet, Lola, Chaynes, Patrick, Groiss, Stefan J., Hartmann, Christian, Südmeyer, Martin, Partowinia-Peters, Mahnaz, Vesper, Jan, Ledily, Severine, Damier, Philippe, Raoul, Sylvie, Trenkwalder, Claudia, Richter-Dreske, Wenke, Wächter, Tobias, Weiss, Daniel, Eusebio, Alexandro, Azulay, Jean Philippe, Polo, Gustavo, Pinto, Serge, Levin, Johannes, Dornier, Stephanie, Pene, Fredy, Hourton, Delphine, Quintin, Mathieu, Hoffart-Jourdain, Cecile, Brocvielle, Helene, Balthasar, Kerstin, Stein, Meryem, Harnisch, Susanne, Reuss, Alexander, Aminossadati, Behnaz, Nasemann, Christian, Oertel, Wolfgang, Bataille, Benoit, Hellwig, Dieter, Gharabaghi, Alireza, Amtage, Florian, Mertens, Patrick, Kloss, Manja, Post, Bart, Speelman, Hans, Lhommée, Eugénie, Wojtecki, Lars, Czernecki, Virginie, Witt, Karsten, Maier, Franziska, Tonder, Lisa, Timmermann, Lars, Hälbig, Thomas D, Pineau, Fanny, Durif, Franck, Witjas, Tatiana, Pinsker, Marcus, Mehdorn, Maximilian, Sixel-Döring, Friederike, Kupsch, Andreas, Krüger, Rejko, Elben, Saskia, Chabardès, Stephan, Thobois, Stéphane, Brefel-Courbon, Christine, Ory-Magne, Fabienne, Regis, Jean-Marie, Maltête, David, Sauvaget, Anne, Rau, Jörn, Schnitzler, Alfons, Schüpbach, Michael, Schade-Brittinger, Carmen, Deuschl, Gunther, Houeto, Jean-Luc, and Krack, Paul

Published
2018
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3. Selecting deep brain stimulation or infusion therapies in advanced Parkinson’s disease: an evidence-based review

Author

Volkmann, Jens, Albanese, Alberto, Antonini, Angelo, Chaudhuri, K. Ray, Clarke, Carl E., de Bie, Rob M. A., Deuschl, Günther, Eggert, Karla, Houeto, Jean-Luc, Kulisevsky, Jaime, Nyholm, Dag, Odin, Per, Østergaard, Karen, Poewe, Werner, Pollak, Pierre, Rabey, Jose Martin, Rascol, Olivier, Ruzicka, Evzen, Samuel, Michael, Speelman, Hans, Sydow, Olof, Valldeoriola, Francesc, van der Linden, Chris, and Oertel, Wolfgang

Published
2013
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12. Contributors

Author

Accardo, Agostino P., primary, Aiple, Franz, additional, Anderson, Tim, additional, Antonini, Riccardo, additional, Barnes, Graham R., additional, Beltrami, Giorgio, additional, Benassi, Carlo, additional, Bengelsdorf, Herbert, additional, Bergamaschi, Roberto, additional, Berthoz, Alain, additional, Paolo Biral, Gian, additional, Bonaventure, Nicole, additional, Bour, Lo J., additional, Braun, Doris, additional, Bruni, Rosa, additional, Callieco, Roberto, additional, Capocchi, Giuseppe, additional, Carmody, Dennis P., additional, Chekaluk, Eugene, additional, Cheron, Guy, additional, Citterio, Antonietta, additional, Tinsley Coble, E., additional, Corazza, Ruggero, additional, Cosi, Vittorio, additional, Crawford, Trevor J., additional, Da Pozzo, Stefano, additional, Dassonville, Paul, additional, De Angelis, Claudio, additional, dell'Aquila, Teresa, additional, Della Torre, Giovannella, additional, Draicchio, Francesco, additional, Duysens, Jacques, additional, d'Ydewalle, Géry, additional, Eadie, Andrew S., additional, Erkelens, Casper J., additional, Errico, Pierangelo, additional, Farrace, Stefano, additional, Ferraresi, Aldo, additional, Fetter, Michael, additional, Findlay, John M., additional, Fischer, Burkhart, additional, Flach, Frederich, additional, Fuchs, Albert F., additional, Galiana, Henrietta L., additional, Godaux, Emile, additional, Grassi, Silvarosa, additional, Grealy, Madeleine A., additional, Guitton, Daniel, additional, Harding, Anita E., additional, Heron, Gordon, additional, Hohnsbein, Joachim, additional, Horii, Ken, additional, Inchingolo, Paolo, additional, Israël, Isabelle, additional, Jagla, Fedor, additional, Jardon, Blandine, additional, Jüttner, Martin, additional, Kaplan, Melvin, additional, Kennard, Christopher, additional, Kim, Myoung-Soon, additional, Koenig, Eberhard, additional, Koken, Phil W., additional, Lefèvre, Philippe, additional, Ling, Leo, additional, Llewellyn, Keith R., additional, Lueck, Christian J., additional, Lui, Fausta, additional, Mateeff, Stefan, additional, Mergner, Thomas, additional, Mettens, Philippe, additional, Mossman, Stuart S., additional, de Visser, Bram W. Ongerboer, additional, Orlowski, Barbara, additional, Paré, Martin, additional, Pensiero, Stefano, additional, Perissutti, Paolo, additional, Pettorossi, Vito Enrico, additional, Phillips, James O., additional, Porcù, Silvio, additional, Pugh, John R., additional, Romani, Alfredo, additional, Roucoux, André, additional, Santarelli, Rosamaria, additional, Schlag, John, additional, Schlag-Rey, Madeleine, additional, Schweigart, Georg, additional, Spagno, Cinzia, additional, Speelman, Hans D., additional, Takeda, Mariko, additional, Tegetmeyer, Helmut, additional, Tweed, Douglas, additional, Uomori, Kenya, additional, Urbani, Luca, additional, van Gisbergen, Jan A.M., additional, Van Rensbergen, Johan, additional, van ′t Ent, Dennis, additional, Versino, Maurizio, additional, Waterston, John A., additional, Weber, Heike, additional, Wolf, Werner, additional, Wolzak, Adrie, additional, Worfolk†, Ralph, additional, Yakimoff, Naum, additional, Yamada, Mitsuho, additional, Yücel, Hasan Y., additional, Zambarbieri, Daniela, additional, Zampolini, Mauro, additional, and Zikmund, Vladislav, additional

Published
1994
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15. Behavioural outcomes of subthalamic stimulation and medical therapy versus medical therapy alone for Parkinson's disease with early motor complications (EARLYSTIM trial): secondary analysis of an open-label randomised trial

Author

Lhommée, Eugénie, primary, Wojtecki, Lars, additional, Czernecki, Virginie, additional, Witt, Karsten, additional, Maier, Franziska, additional, Tonder, Lisa, additional, Timmermann, Lars, additional, Hälbig, Thomas D, additional, Pineau, Fanny, additional, Durif, Franck, additional, Witjas, Tatiana, additional, Pinsker, Marcus, additional, Mehdorn, Maximilian, additional, Sixel-Döring, Friederike, additional, Kupsch, Andreas, additional, Krüger, Rejko, additional, Elben, Saskia, additional, Chabardès, Stephan, additional, Thobois, Stéphane, additional, Brefel-Courbon, Christine, additional, Ory-Magne, Fabienne, additional, Regis, Jean-Marie, additional, Maltête, David, additional, Sauvaget, Anne, additional, Rau, Jörn, additional, Schnitzler, Alfons, additional, Schüpbach, Michael, additional, Schade-Brittinger, Carmen, additional, Deuschl, Gunther, additional, Houeto, Jean-Luc, additional, Krack, Paul, additional, Negovanska, Velina, additional, Welter, Marie-Laure, additional, Corvol, Jean-Christophe, additional, Agid, Yves, additional, Navarro, Soledad, additional, Meier, Niklaus, additional, Hartmann, Andreas, additional, Hesekamp, Helke, additional, Cornu, Philippe, additional, Möller, Bettina, additional, Nebel, Adelheid, additional, Raethjen, Jan, additional, Knudsen, Karina, additional, Volkmann, Jens, additional, Falk, Daniela, additional, Paschen, Steffen, additional, Meister, Ingo, additional, Kuhn, Jens, additional, Donner, Kerstin, additional, Kessler, Josef, additional, Barbe, Michael, additional, Fink, Gereon, additional, Maarouf, Mohammad, additional, Kühn, Andrea, additional, Müller, Bianca, additional, Faust, Katharina, additional, Gruber, Doreen, additional, Schneider, Gerd-H., additional, Seigneuret, Eric, additional, Pollak, Pierre, additional, Fraix, Valerie, additional, Kistner, Andrea, additional, Rascol, Olivier, additional, Arbus, Christophe, additional, Danet, Lola, additional, Chaynes, Patrick, additional, Groiss, Stefan J., additional, Hartmann, Christian, additional, Südmeyer, Martin, additional, Partowinia-Peters, Mahnaz, additional, Vesper, Jan, additional, Ledily, Severine, additional, Damier, Philippe, additional, Raoul, Sylvie, additional, Trenkwalder, Claudia, additional, Richter-Dreske, Wenke, additional, Wächter, Tobias, additional, Weiss, Daniel, additional, Eusebio, Alexandro, additional, Azulay, Jean Philippe, additional, Polo, Gustavo, additional, Pinto, Serge, additional, Levin, Johannes, additional, Dornier, Stephanie, additional, Pene, Fredy, additional, Hourton, Delphine, additional, Quintin, Mathieu, additional, Hoffart-Jourdain, Cecile, additional, Brocvielle, Helene, additional, Balthasar, Kerstin, additional, Stein, Meryem, additional, Harnisch, Susanne, additional, Reuss, Alexander, additional, Aminossadati, Behnaz, additional, Nasemann, Christian, additional, Oertel, Wolfgang, additional, Bataille, Benoit, additional, Hellwig, Dieter, additional, Gharabaghi, Alireza, additional, Amtage, Florian, additional, Mertens, Patrick, additional, Kloss, Manja, additional, Post, Bart, additional, and Speelman, Hans, additional

Published
2018
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24. Tendon Reflex Asymmetry by Voluntary Mental Effort in Healthy Subjects

Author

Stam, Jan, Speelman, Hans D., and van Crevel, Hans

Abstract

• The effect of voluntary mental influences on the tendon reflexes was examined in healthy subjects. The patellar reflexes were evoked by a method comparable with the clinical examination, and the reflexes were recorded by surface electrodes. Eighteen subjects were instructed to increase and then decrease the right patellar reflex by mental effort, without contracting any muscles. Most subjects increased the reflex in both conditions. Subsequently, ten subjects were instructed to increase the right patellar reflex and decrease the left by mental effort. Measurement showed reflex asymmetry in seven subjects consistent with the instruction. The experiment was repeated in another 20 subjects with symmetric reflexes at rest. Ten of these subjects were, after random assignment, instructed to increase either the right or the left knee jerk. All subjects (and an additional 15 asymmetric control subjects) were examined by a neurologist without knowledge of the instruction. Three of the ten instructed subjects were correctly judged to be asymmetric, but the agreement between instruction and neurologic judgment was not statistically significant. Mentally induced reflex asymmetry is possible, and may be clinically relevant in some cases.

Published
1989
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25. EXPRESSION OF HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN (HIV-Ag) IN SERUM AND CEREBROSPINAL FLUID DURING ACUTE AND CHRONIC INFECTION

Author

Goudsmit, Jaap, primary, Paul, DeborahA., additional, Lange, JoepM.A., additional, Speelman, Hans, additional, Van Der Noordaa, Jan, additional, Van Der Helm, HayoJ., additional, De Wolf, Frank, additional, Epstein, LeonG., additional, Krone, WillyJ.A., additional, Wolters, EricCh., additional, Oleske, JamesM., additional, and Coutinho, RoelA., additional

Published
1986
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28. Innovation

Author

Renu Agarwal, Eric Patterson, Sancheeta Pugalia, Roy Green, Renu Agarwal, Eric Patterson, Sancheeta Pugalia, and Roy Green

Subjects
Information technology--Management, Business enterprises--Technological innovations
Abstract

In recent years, a great deal of attention has been focussed on the undertaking of managing innovation. Without the right focus, resourcing and capabilities, firms struggle to create value through innovation. However, the task of managing innovation is one of continuous paradoxes where an overly structured mind-set can impede entrepreneurship, creativity, culture and the right conditions for disruption. The question remains of how we can have the right lens to properly understand and appreciate innovation, and how we can have a flexible set of tools, techniques and perspectives to support innovation. This concise text introduces readers to one of the fundamental ideas in the business world.Insights into the key ingredients of innovation, including business models, services, entrepreneurship and creativity are analysed alongside core contexts, such as disruptive technology. Students of business and management will appreciate additional coverage of the future of the field, including open innovation and the dark side of digital disruption.This accessible book provides a thought-provoking, stimulating perspective that will make it a valuable resource for a range of academic and student audiences across business and management disciplines.

Published
2022

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