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2,998 results on '"Soriguer F"'

1. Fatty liver index as a predictor for type 2 diabetes in subjects with normoglycemia in a nationwide cohort study

Author

García-Escobar, E., Valdés, S., Soriguer, F., Vendrell, J., Urrutia-Etxebarria, I. M., Maldonado-Araque, C., Ortega, E., Ocón, P., Montanya, E., Menéndez, E., Lago-Sampedro, A., González-Frutos, T., Gomis, R., Goday, A., García-Serrano, S., Galán-García, J. L., Castell, C., Bordiú, E., Badía, R., Aguilera-Venegas, G., Girbés, J., Gaztambide, S., Delgado, E., Chaves, F. J., Castaño, L., Calle-Pascual, A., Rojo-Martínez, G., and Franch-Nadal, J.

Published
2021
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3. Incidence of diabetes mellitus in Spain as results of the nation-wide cohort di@bet.es study

Author

Rojo-Martínez, G., Valdés, S., Soriguer, F., Vendrell, J., Urrutia, I., Pérez, V., Ortega, E., Ocón, P., Montanya, E., Menéndez, E., Lago-Sampedro, A., González- Frutos, T., Gomis, R., Goday, A., García-Serrano, S., García-Escobar, E., Galán-García, J. L., Castell, C., Badía-Guillén, R., Aguilera-Venegas, G., Girbés, J., Gaztambide, S., Franch-Nadal, J., Delgado, E., Chaves, F. J., Castaño, L., and Calle-Pascual, A.

Published
2020
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7. Mediterranean Diet Adherence in Individuals with Prediabetes and Unknown Diabetes : The Di@bet.es Study

Author

Ortega, E., Franch, J., Castell, C., Goday, A., Ribas-Barba, L., Soriguer, F., Vendrell, J., Casamitjana, R., Bosch-Comas, A., Bordiú, E., Calle-Pascual, A., Carmena, R., Castaño, L., Catalá, M., Delgado, E., Gaztambide, S., Girbés, J., López-Alba, A., Martínez-Larrad, M.T., Menéndez, E., Mora-Peces, I., Pascual-Manich, G., Rojo-Martínez, G., Serrano-Rios, M., Urrutía, I., Valdés, S., Vázquez, J. A., and Gomis, R.

Published
2013

8. Iodine intake in the adult population. Di@bet.es study

Author

Soriguer, F., García-Fuentes, E., Gutierrez-Repiso, C., Rojo-Martínez, G., Velasco, I., Goday, A., Bosch-Comas, A., Bordiú, E., Calle, A., Carmena, R., Casamitjana, R., Castaño, L., Castell, C., Catalá, M., Delgado, E., Franch, J., Gaztambide, S., Girbés, J., Gomis, R., Gutiérrez, G., López-Alba, A., Martínez-Larrad, M.T., Menéndez, E., Mora-Peces, I., Ortega, E., Pascual-Manich, G., Serrano-Rios, M., Valdés, S., Vázquez, J.A., and Vendrell, J.

Published
2012
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10. The high climate vulnerability of western Mediterranean forests.

Author

Hidalgo-Triana N, Solakis A, Casimiro-Soriguer F, Choe H, Navarro T, Pérez-Latorre AV, and Thorne JH

Subjects
Trees, Biodiversity, Climate Change, Ecosystem, Carbon Dioxide, Forests
Abstract

Understanding the effects of climate change is one of the most challenging goals for biodiversity conservation. The forests of Andalusia, in Southern Spain, are part of an important Mediterranean Basin biodiversity hotspot. However, great changes in climate are expected to occur in this region, and there is an increasing need to assess the vulnerability of its vegetation. We assess the vulnerability of twelve forest types in the region that are included in the European Directive 92/43/EEC as Habitats of Community Interest (HCI). HCI are natural habitat types which are in danger, have a small natural range, or present an outstanding example of a biogeographical regions in the European Union. We assessed vulnerability by analyzing the climate exposure level of each forest type under two global climate models (MRI-CGCM3, which predicts warmer and wetter conditions, and MIROC-ESM which predicts hotter and drier conditions), two emission scenarios (RCP4.5, a representative concentration pathway that predicts stable emissions of CO 2 , and RCP8.5, that predicts the highest CO 2 emissions) by the mid- and end-century time periods. The vulnerability analysis also includes the sensitivity and adaptive capacity of the dominant tree species which compose each forest type. An overall vulnerability score was calculated for each forest type, model, scenario and time period. High-elevation forest types and those with high moisture requirements were more vulnerable to climate change, while forest types dominated by more thermophilic species were less vulnerable and more resilient. The worst climate impacts were predicted in the MIROC-ESM model and RCP8.5 scenario by the end of the century (2070-2100), while the least climatic stress was obtained in the MRI-CGCM3 model and RCP4.5 scenario by the mid-century (2040-2070), which still shows high potential stress for most forest types. By the end of the century, the climate exposure of the entire forest domain will range between 32 % in the least stressful situation (MRI-CGCM3 and RCP4.5), and 98 % in the most climatically stressful situation (MIROC-ESM and RCP8.5). However, the effects of climate change will be perceptible by the mid-century, with most of the HCI forest types suffering climate stress. The "Andalusian oak forest" and the "Corylus wet forest" types were the most vulnerable to climate change, while the "Mediterranean pine forest", the "Olea and Ceratonia forests" and the "oak forests" were the least vulnerable. This assessment identifies the vulnerable forest types to climate change in the south of the Iberian Peninsula, and provides context for natural resource managers in making decisions about how to adapt forests to the impacts of climate change., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.)

Published
2023
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13. Olive oil has a beneficial effect on impaired glucose regulation and other cardiometabolic risk factors. Di@bet.es study

Author

Soriguer, F., Rojo-Martinez, G., Goday, A., Bosch-Comas, A., Bordiu, E., Caballero-Diaz, F., Calle-Pascual, A., Carmena, R., Casamitjana, R., Castano, L., Castell, C., Catala, M., Delgado, E., Franch, J., Gaztambide, S., Girbes, J., Gomis, R., Gutierrez, G., Lopez-Alba, A., Martinez-Larrad, M. Teresa, Menendez, E., Mora-Peces, I., Ortega, E., Pascual-Manich, G., Serrano-Rios, M., Urrutia, I., Valdes, S., Vazquez, J. Antonio, and Vendrell, J.

Subjects
Olive oil -- Health aspects, Diabetes -- Physiological aspects -- Risk factors, Glucose metabolism -- Research, Food/cooking/nutrition, Health
Abstract

BACKGROUND: Despite the marked increase in cardiovascular risk factors in Spain in recent years, the prevalence and incidence of cardiovascular diseases have not risen as expected. Our objective is to examine the association between consumption of olive oil and the presence of cardiometabolic risk factors in the context of a large study representative of the Spanish population. SUBJECTS AND METHODS: A population-based, cross-sectional, cluster sampling study was conducted. The target population was the whole Spanish population. A total of 4572 individuals aged ≥ 18 years in 100 clusters (health centers) were randomly selected with a probability proportional to population size. The main outcome measures were clinical and demographic structured survey, lifestyle survey, physical examination (weight, height, body mass index, waist, hip and blood pressure) and oral glucose tolerance test (OGTT) (75 g). RESULTS: Around 90% of the Spanish population use olive oil, at least for dressing, and slightly fewer for cooking or frying. The preference for olive oil is related to age, educational level, alcohol intake, body mass index and serum glucose, insulin and lipids. People who consume olive oil (vs sunflower oil) had a lower risk of obesity (odds ratio (OR) = 0.62 (95% confidence interval (CI) = 0.41-0.93, P = 0.02)), impaired glucose regulation (OR = 0.49 (95% CI = 0.28-0.86, P = 0.04)), hypertriglyceridemia (OR = 0.53 (95% CI = 0.33-0.84, P = 0.03)) and low HDL cholesterol levels (OR = 0.40 (95% CI = 0.26-0.59, P = 0.0001)). CONCLUSIONS: The results show that consumption of olive oil has a beneficial effect on different cardiovascular risk factors, particularly in the presence of obesity, impaired glucose tolerance or a sedentary lifestyle. European Journal of Clinical Nutrition (2013) 67, 911-916; doi:10.1038/ejcn.2013.130; published online 17 July 2013 Keywords: olive oil; diabetes; impaired glucose regulation; obesity; population-based study; cardiovascular risk, INTRODUCTION The high rates of morbidity and mortality due to cardiovascular diseases represent one of the greatest social and health care problems in developed countries, as well as in many [...]

Published
2013
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14. Prevalence of diabetes mellitus and impaired glucose regulation in Spain: the Di@bet.es Study

Author

Soriguer, F., Goday, A., Bosch-Comas, A., Bordiú, E., Calle-Pascual, A., Carmena, R., Casamitjana, R., Castaño, L., Castell, C., Catalá, M., Delgado, E., Franch, J., Gaztambide, S., Girbés, J., Gomis, R., Gutiérrez, G., López-Alba, A., Martínez-Larrad, M. T., Menéndez, E., Mora-Peces, I., Ortega, E., Pascual-Manich, G., Rojo-Martínez, G., Serrano-Rios, M., Valdés, S., Vázquez, J. A., and Vendrell, J.

Published
2012
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16. Risk factors associated with retinal vein occlusion

Author

Martínez, F., Furió, E., Fabiá, M. J., Pérez, A. V., González-Albert, V., Rojo-Martínez, G., Martínez-Larrad, M. T., Mena-Martín, F. J., Soriguer, F., Serrano-Ríos, M., Chaves, F. J., Martín-Escudero, J. C., Redón, J., and García-Fuster, M. J.

Published
2014
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18. Clinical dilemmas arising from the increased intake of iodine in the Spanish population and the recommendation for systematic prescription of potassium iodide in pregnant and lactating women (Consensus of the TDY Working Group of SEEN)

Author

Soriguer, F., Santiago, P., Vila, L., Arena, J. M., Delgado, E., Cadórniga, F. Díaz, Donnay, S., Soto, M. Fernández, González-Romero, S., Martul, P., Domingo, M. Puig, Ares, S., del Rey, F. Escobar, and de Escobar, G. Morreale

Published
2009
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20. Iodine Deficiency and Mortality in Spanish Adults: Di@bet.es Study

Author

Maldonado-Araque C, Valdes S, Badia-Guillen R, Lago-Sampedro A, Colomo N, Garcia-Fuentes E, Gutierrez-Repiso C, Goday-Arno A, Calle-Pascual A, Castano L, Castell C, Delgado Alvarez E, Menendez Torre E, Franch-Nadal J, Gaztambide S, Girbes J, Chaves F, Soriguer F, and Rojo-Martinez G

Subjects
iodine, Spain, epidemiology, mortality
Abstract

BACKGROUND: Longitudinal data assessing the impact of Iodine deficiency on mortality are scarce. We aimed to study the association between the state of iodine nutrition and the risk of total and cause-specific mortality in a representative sample of the Spanish adult population.; METHODS: We performed a longitudinal observational study to estimate mortality risk according to urinary iodine (UI) concentrations using a sample of 4370 subjects >18 years representative of the Spanish adult population participating in the nation-wide study Di@bet.es (2008-2010). We used Cox regression to assess the association between UI at the start of the study (

Published
2021

21. Fatty liver index as a predictor for type 2 diabetes in subjects with normoglycemia in a nationwide cohort study

Author

Universitat Rovira i Virgili, Garcia-Escobar, E.; Valdes, S.; Soriguer, F.; Vendrell, J.; Urrutia-Etxebarria, I. M.; Maldonado-Araque, C.; Ortega, E.; Ocon, P.; Montanya, E.; Menendez, E.; Lago-Sampedro, A.; Gonzalez-Frutos, T.; Gomis, R.; Goday, A.; Garcia-Serrano, S.; Galan-Garcia, J. L.; Castell, C.; Bordiu, E.; Badia, R.; Aguilera-Venegas, G.; Girbes, J.; Gaztambide, S.; Delgado, E.; Chaves, F. J.; Castano, L.; Calle-Pascual, A.; Rojo-Martinez, G.; Franch-Nadal, J., Universitat Rovira i Virgili, and Garcia-Escobar, E.; Valdes, S.; Soriguer, F.; Vendrell, J.; Urrutia-Etxebarria, I. M.; Maldonado-Araque, C.; Ortega, E.; Ocon, P.; Montanya, E.; Menendez, E.; Lago-Sampedro, A.; Gonzalez-Frutos, T.; Gomis, R.; Goday, A.; Garcia-Serrano, S.; Galan-Garcia, J. L.; Castell, C.; Bordiu, E.; Badia, R.; Aguilera-Venegas, G.; Girbes, J.; Gaztambide, S.; Delgado, E.; Chaves, F. J.; Castano, L.; Calle-Pascual, A.; Rojo-Martinez, G.; Franch-Nadal, J.

Abstract

Our aim was to evaluate whether fatty liver index (FLI) is associated with the risk of type 2 diabetes (T2DM) development within the Spanish adult population and according to their prediabetes status; additionally, to examine its incremental predictive value regarding traditional risk factors. A total of 2260 subjects (Prediabetes: 641 subjects, normoglycemia: 1619 subjects) from the Di@bet.es cohort study were studied. Socio-demographic, anthropometric, clinical data and survey on habits were recorded. An oral glucose tolerance test was performed and fasting determinations of glucose, lipids and insulin were made. FLI was calculated and classified into three categories: Low (< 30), intermediate (30-60) and high (> 60). In total, 143 people developed diabetes at follow-up. The presence of a high FLI category was in all cases a significant independent risk factor for the development of diabetes. The inclusion of FLI categories in prediction models based on different conventional T2DM risk factors significantly increase the prediction power of the models when all the population was considered. According to our results, FLI might be considered an early indicator of T2DM development even under normoglycemic condition. The data also suggest that FLI could provide additional information for the prediction of T2DM in models based on conventional risk factors.

Published
2021

25. Thyroid hormone receptor alpha gene variants increase the risk of developing obesity and show gene-diet interactions

Author

Fernández-Real, J M, Corella, D, Goumidi, L, Mercader, J M, Valdés, S, Martínez, Rojo G, Ortega, F, Martinez-Larrad, M-T, Gómez-Zumaquero, J M, Salas-Salvadó, J, Martinez González, M A, Covas, M I, Botas, P, Delgado, E, Cottel, D, Ferrieres, J, Amouyel, P, Ricart, W, Ros, E, Meirhaeghe, A, Serrano-Rios, M, Soriguer, F, and Estruch, R

Published
2013
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37. Incidence and regression of metabolic syndrome in a representative sample of the Spanish population: results of the cohort di@bet

Author

Universitat Rovira i Virgili, Cuesta M; Fuentes M; Rubio M; Bordiu E; Barabash A; Garcia de la Torre N; Rojo-Martinez G; Valdes S; Soriguer F; Vendrell JJ; Urrutia IM; Ortega E; Montanya E; Menendez E; Lago-Sampedro A; Gomis R; Goday A; Castell C; Badia-Guillen R; Girbés J; Gaztambide S; Franch-Nadal J; Delgado Álvarez E; Chaves FJ; Castano L; Calle-Pascual AL, Universitat Rovira i Virgili, and Cuesta M; Fuentes M; Rubio M; Bordiu E; Barabash A; Garcia de la Torre N; Rojo-Martinez G; Valdes S; Soriguer F; Vendrell JJ; Urrutia IM; Ortega E; Montanya E; Menendez E; Lago-Sampedro A; Gomis R; Goday A; Castell C; Badia-Guillen R; Girbés J; Gaztambide S; Franch-Nadal J; Delgado Álvarez E; Chaves FJ; Castano L; Calle-Pascual AL

Abstract

Introduction Metabolic syndrome (MetS) is an important predictor of cardiovascular mortality. Identification of occurrence and regression trends of MetS could permit elaboration of preventive strategies with new targets. The objective of this study was to analyze the occurrence and regression rates of MetS and its associated factors in the representative cohort of Spain of the di@bet.es study. Research design and methods The di@bet.es study is a prospective cohort where 5072 people representative of the Spanish population over 18 years of age were randomly selected between 2009 and 2010. Follow-up was a median of 7.5 (IQR 7.2-7.9) years, with 2408 (47%) participating subjects. A total of 1881 (78%) subjects had all the pertinent data available and were included in this study. Results Of the 1146 subjects without baseline criteria for MetS, 294 (25.7%) developed MetS during follow-up, while of the 735 patients with prior MetS, 148 (20.1%) presented regression. Adjusted MetS incidence per 1000 person-years was 38 (95% CI 32 to 44), while regression incidence was 36 (95% CI 31 to 41). Regression rate was independently higher than incidence rate in the following: women, subjects aged 18-45, university-degree holders, patients without central obesity, without hypertension, as well as those with body mass index of <25 kg/m(2). Lower progression and higher regression rates were observed with an adapted 14-point Mediterranean Diet adherence screener questionnaire score of >11 in both groups and with >500 and >2000 MET-min/week of physical activity, respectively. Conclusions This study provides MetS incidence and regression rates, and identifies the target population for intervention strategies in Spain and possibly in other countries.

Published
2020

40. Ambient air pollution and thyroid function in Spanish adults. A nationwide population-based study (Di@bet.es study).

Author

Valdés S, Doulatram-Gamgaram V, Maldonado-Araque C, Lago-Sampedro A, García-Escobar E, García-Serrano S, García-Vivanco M, Garrido Juan L, Theobald MR, Gil V, Martín-Llorente F, Ocon P, Calle-Pascual A, Castaño L, Delgado E, Menendez E, Franch-Nadal J, Gaztambide S, Girbés J, Chaves FJ, Galán-García JL, Aguilera-Venegas G, Gutierrez-Repiso C, Fernández-García JC, Colomo N, Soriguer F, García-Fuentes E, and Rojo-Martínez G

Subjects
Adult, Cross-Sectional Studies, Female, Humans, Male, Nitrogen Dioxide analysis, Particulate Matter analysis, Thyroid Gland chemistry, Thyroid Hormones, Thyrotropin, Air Pollutants adverse effects, Air Pollutants analysis, Air Pollution analysis
Abstract

Background: Recent reports have suggested that air pollution may impact thyroid function, although the evidence is still scarce and inconclusive. In this study we evaluated the association of exposure to air pollutants to thyroid function parameters in a nationwide sample representative of the adult population of Spain., Methods: The Di@bet.es study is a national, cross-sectional, population-based survey which was conducted in 2008-2010 using a random cluster sampling of the Spanish population. The present analyses included 3859 individuals, without a previous thyroid disease diagnosis, and with negative thyroid peroxidase antibodies (TPO Abs) and thyroid-stimulating hormone (TSH) levels of 0.1-20 mIU/L. Participants were assigned air pollution concentrations for particulate matter <2.5μm (PM 2.5 ) and Nitrogen Dioxide (NO 2 ), corresponding to the health examination year, obtained by means of modeling combined with measurements taken at air quality stations (CHIMERE chemistry-transport model). TSH, free thyroxine (FT4), free triiodothyronine (FT3) and TPO Abs concentrations were analyzed using an electrochemiluminescence immunoassay (Modular Analytics E170 Roche)., Results: In multivariate linear regression models, there was a highly significant negative correlation between PM 2.5 concentrations and both FT4 (p<0.001), and FT3 levels (p<0.001). In multivariate logistic regression, there was a significant association between PM 2.5 concentrations and the odds of presenting high TSH [OR 1.24 (1.01-1.52) p=0.043], lower FT4 [OR 1.25 (1.02-1.54) p=0.032] and low FT3 levels [1.48 (1.19-1.84) p=<0.001] per each IQR increase in PM 2.5 (4.86 μg/m 3 ). There was no association between NO 2 concentrations and thyroid hormone levels. No significant heterogeneity was seen in the results between groups of men, pre-menopausal and post-menopausal women., Conclusions: Exposures to PM 2.5 in the general population were associated with mild alterations in thyroid function., (© 2022. The Author(s).)

Published
2022
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45. Dairy Product Consumption and Metabolic Diseases in the Di@bet.es Study

Author

Lago-Sampedro A, García-Escobar E, Rubio-Martín E, Pascual-Aguirre N, Valdés S, Soriguer F, Goday A, Calle-Pascual A, Castell C, Menéndez E, Delgado E, Bordiú E, Castaño L, Franch-Nadal J, Girbés J, Chaves FJ, Gaztambide S, Rojo-Martínez G, and Olveira G

Published
2019

47. Cytogenetic, Morphometric, and Ecological Characterization of Festuca indigesta Boiss. in the Southeast of Spain.

Author

Martínez-Sagarra G, Casimiro-Soriguer F, Castro S, Loureiro J, and Devesa JA

Abstract

Festuca indigesta subsp. indigesta (Poaceae) is endemic to the southeast of Spain, and until recently, it was considered that its range of distribution was restricted to the siliceous core of Sierra Nevada. However, it has been recently extended in the territory to others calcareous mountains. This study investigates the cytogenetic variability throughout the geographic range of this taxon, the possible edaphic preferences of each cytotype, and the morphological variation of cytotypes. Genome sizes and ploidy levels were estimated using flow cytometry and chromosome count. Soil samples were collected to test the nature of the substrate, i.e., pH, and calcium and magnesium contents. Finally, morphological characters were measured in herbarium specimens. This study provides the first genome size data for the species. Hidden cytogenetic diversity was detected in the taxon, comprising hexaploid (2n = 6 x = 42), octoploid (2n = 8 x = 56) and dodecaploid (2n = 12 x = 84) individuals. No relationship between substrate nature and cytotype was observed. Morphological differences were detected for the size of floral parts and stomata among cytotypes, but these were blurred if the entire morphological variation range was considered. Our results suggest that each mountain range could act as a reservoir of morphologically cryptic genetic diversity regarding this taxon.

Published
2022
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