Search

Your search keyword '"Sale, Michelle"' showing total 145 results
Start Over "Sale, Michelle"

Refine your results

more »

more »

more »

more »

more »
145 results on '"Sale, Michelle"'

1. Michelle Keegan's padded autumn jacket that 'fits perfectly' is in the sale; Michelle Keegan has an enviable autumn wardrobe that we love to copy -and you can currently get one of her latest Very pieces for less

Subjects
Nylon, General interest, News, opinion and commentary, Instagram (Online service)
Abstract

Byline: By, Melisha Kaur Michelle Keegan's new clothing collection with Very is full of stylish autumn staples -- and one of her must-have layering pieces has just had a discount. [...]

Published
2023

2. Association of Apolipoprotein e with Intracerebral Hemorrhage Risk by Race/Ethnicity : A Meta-analysis

Author

Marini, Sandro, Crawford, Katherine, Morotti, Andrea, Lee, Myung J, Pezzini, Alessandro, Moomaw, Charles J, Flaherty, Matthew L, Montaner, Joan, Roquer, Jaume, Jimenez-Conde, Jordi, Giralt-Steinhauer, Eva, Elosua, Roberto, Cuadrado-Godia, Elisa, Soriano-Tarraga, Carolina, Slowik, Agnieszka, Jagiella, Jeremiasz M, Pera, Joanna, Urbanik, Andrzej, Pichler, Alexander, Hansen, Bjorn M, McCauley, Jacob L, Tirschwell, David L, Selim, Magdy, Brown, Devin L, Silliman, Scott L, Worrall, Bradford B, Meschia, James F, Kidwell, Chelsea S, Testai, Fernando D, Kittner, Steven J, Schmidt, Helena, Enzinger, Christian, Deary, Lan J, Rannikmae, Kristiina, Samarasekera, Neshika, Salman, Rustam Al-Shahi, Sudlow, Catherine L, Klijn, Catharina JM, van Nieuwenhuizen, Koen M, Fernandez-Cadenas, Israel, Delgado, Pilar, Nonving, Bo, Lindgren, Ame, Goldstein, Joshua N, Viswanathan, Anand, Greenberg, Steven M, Falcone, Guido J, Biffi, Alessandro, Langefeld, Carl D, Woo, Daniel, Rosand, Jonathan, Anderson, Christopher D, Smoller, Sylvia, Sorkin, John, Wang, Xingwu, Pikula, Aleksandra, Wolf, Philip, Debette, Stephanie, Seshadri, Sudha, de Bakker, Paul, Chasman, Daniel, Rexrode, Kathryn, Chen, Ida, Rotter, Jerome, Luke, May, Sale, Michelle, Lee, Tsong-Hai, Chang, Ku-Chou, Elkind, Mitchell, Goldstein, Larry, James, Michael Luke, Breteler, Monique, O'Donnell, Chris, Leys, Didier, Carty, Cara, Kidwell, Chelsea, Olesen, Jes, Sharma, Pankaj, Rich, Stephen, Tatlisumak, Turgot, Happola, Olli, Bijlenga, Philippe, Soriano, Carolina, Giralt, Eva, Cotlarcius, Loana, Hardy, John, Korostynski, Michal, Boncoraglio, Giorgio, Ballabio, Elena, Parati, Eugenio, Mateusz, Adamski, Dziedzic, Tomasz, Jagiella, Jeremiasz, Gasowski, Jerzy, Wnuk, Marcin, Olszanecki, Rafaf, Juchniewicz, Karol Jozef, Levi, Christopher, Nyquist, Paul, Cendes, Iscia, Cabral, Norberto, Franca, Paulo, Goncalves, Anderson, Keller, Lina, Crisby, Milita, Kostulas, Konstantinos, Lennnnens, Robin, Ahmadi, Kourosh, Opherk, Christian, Duering, Marco, Dichgans, Martin, Malik, Rainer, Gonik, Mariya, Staals, Julie, Melander, Olle, Burri, Philippe, Sadr-Nabavi, Ariane, Romero, Javier, Anderson, Chris, Falcone, Guido, Brouwers, Bart, Rost, Natalia, Du, Rose, Kourkoulis, Christina, Battey, Thomas, Lubitz, Steven, Mueller-Myhsok, Bertram, Meschia, James, Brott, Thomas, Pare, Guillaume, Schmidt, Reinhold, Seiler, Stephan, Blanton, Susan, Yamada, Yoshiji, Bersano, Anna, Rundek, Tatiana, Sacco, Ralph, Chan, Yu-Feng Yvonne, Gschwendtner, Andreas, Deng, Zhen, Barr, Taura, Gwinn, Katrina, Corriveau, Roderick, Singleton, Andrew, Waddy, Salina, Launer, Lenore, Chen, Christopher, Le, Kim En, Lee, Wei Ling, Tan, Eng King, Olugbodi, Akintomi, Rothwell, Peter, Schilling, Sabrina, Mok, Vincent, Lebedeva, Elena, Jem, Christina, Jood, Katarina, Olsson, Sandra, Kim, Helen, Lee, Chaeyoung, Kilarski, Laura, Markus, Hugh, Peycke, Jennifer, Bevan, Steve, Sheu, Wayne, Chiou, Hung Yi, Chern, Joseph, Giraldo, Elias, Taqi, Muhammad, Jain, Vivek, Lam, Olivia, Howard, George, Kittner, Steven, Mitchell, Braxton, Cole, John, O'Connell, Jeff, Milewicz, Dianna, Illoh, Kachikwu, Worrall, Bradford, Stine, Colin, Karaszewski, Bartosz, Werring, David, Sofat, Reecha, Smalley, June, Lindgren, Arne, Hansen, Bjorn, Norrving, Bo, Smith, Gustav, Martin, Juan Jose, Thijs, Vincent, Klijn, Karin, van't Hof, Femke, Algra, Ale, Macleod, Mary, Perry, Rodney, Arnett, Donna, Padovani, Alessandro, Cramer, Steve, Fisher, Marl, Saleheen, Danish, Broderick, Joseph, Kissela, Brett, Doney, Alex, Sudlow, Cathie, Silliman, Scott, McDonough, Caitrin, Walters, Matthew, Pedersen, Annie, Nakagawa, Kazuma, Chang, Christy, Dobbins, Mark, McArdle, Patrick, Chang, Yu-Ching, Brown, Robert, Brown, Devin, Holliday, Elizabeth, Kalaria, Raj, Maguire, Jane, Hunter, John, Attia, John, Farrall, Martin, Giese, Anne-Katrin, Fomage, Myriam, Majersik, Jennifer, Cushman, Maly, Keene, Keith, Bennett, Siiri, Tirschwell, David, Psaty, Bruce, Reiner, Alex, Longstreth, Will, Spence, David, Langefeld, Carl, Bushnell, Cheryl, Heitsch, Laura, Lee, Jin-Moo, Sheth, Kevin, Consortium, Int Genetics, Neurologian yksikkö, Department of Neurosciences, Clinicum, Doctoral Programme in Clinical Research, HUS Neurocenter, RS: Carim - B05 Cerebral small vessel disease, RS: CARIM - R3.03 - Cerebral small vessel disease, and Epidemiology

Subjects
Male, Race ethnicity, Hemorràgia cerebral, 3124 Neurology and psychiatry, 0302 clinical medicine, Risk Factors, WHITES, BLACKS, 030212 general & internal medicine, Biological sciences, Original Investigation, ALZHEIMER-DISEASE, African Americans, Aged, 80 and over, GENETIC-VARIATION, Hispanic or Latino, Middle Aged, Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3], Medical research, University hospital, 3. Good health, ETHNICITY, ALLELE, Research centre, Hypertension, lipids (amino acids, peptides, and proteins), Female, Apolipoprotein E, Core laboratory, Hispanic Americans, medicine.medical_specialty, COA REDUCTASE INHIBITORS, European Continental Ancestry Group, Clinical Neurology, Raça, APOE EPSILON-4, White People, 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, Apolipoproteins E, Political science, medicine, Journal Article, Online First, Humans, Genetic Predisposition to Disease, cardiovascular diseases, General hospital, Aged, Cerebral Hemorrhage, Research, LOBAR, 3112 Neurosciences, E GENOTYPE, United States, nervous system diseases, Black or African American, Cognitive epidemiology, Family medicine, Case-Control Studies, Neurology (clinical), 030217 neurology & neurosurgery
Abstract

Key Points Question Is history of hypertension and apolipoprotein E (APOE) associated with intracerebral hemorrhage risk in participants stratified by self-reported race/ethnicity? Findings In this case-control study of 13 124 adults, having a copy of APOE ε4 alleles increased the risk for lobar intracerebral hemorrhage only in white individuals, but after propensity score matching for hypertension burden, Hispanic individuals showed the same risk of APOE ε4. Meaning APOE ε4 appears to be confirmed as a risk factor for lobar intracerebral hemorrhage in nonwhite populations but is masked by differential hypertension burden in Hispanic individuals; further studies are needed to explore the interactions between APOE alleles and environmental exposures., Importance Genetic studies of intracerebral hemorrhage (ICH) have focused mainly on white participants, but genetic risk may vary or could be concealed by differing nongenetic coexposures in nonwhite populations. Transethnic analysis of risk may clarify the role of genetics in ICH risk across populations. Objective To evaluate associations between established differences in ICH risk by race/ethnicity and the variability in the risks of apolipoprotein E (APOE) ε4 alleles, the most potent genetic risk factor for ICH. Design, Setting, and Participants This case-control study of primary ICH meta-analyzed the association of APOE allele status on ICH risk, applying a 2-stage clustering approach based on race/ethnicity and stratified by a contributing study. A propensity score analysis was used to model the association of APOE with the burden of hypertension across race/ethnic groups. Primary ICH cases and controls were collected from 3 hospital- and population-based studies in the United States and 8 in European sites in the International Stroke Genetic Consortium. Participants were enrolled from January 1, 1999, to December 31, 2017. Participants with secondary causes of ICH were excluded from enrollment. Controls were regionally matched within each participating study. Main Outcomes and Measures Clinical variables were systematically obtained from structured interviews within each site. APOE genotype was centrally determined for all studies. Results In total, 13 124 participants (7153 [54.5%] male with a median [interquartile range] age of 66 [56-76] years) were included. In white participants, APOE ε2 (odds ratio [OR], 1.49; 95% CI, 1.24-1.80; P, This case-control study examines whether the risk for intracerebral hemorrhage presented by apolipoprotein E ε4 and ε2 alleles varies by race/ethnicity.

Published
2019

3. Variants conferring risk of atrial fibrillation on chromosome 4q25

Author

Gudbjartsson, Daniel F., Arnar, David O., Helgadottir, Anna, Gretarsdottir, Solveig, Holm, Hilma, Sigurdsson, Asgeir, Jonasdottir, Adalbjorg, Baker, Adam, Thorleifsson, Gudmar, Kristjansson, Kristleifur, Palsson, Arnar, Blondal, Thorarinn, Sulem, Patrick, Backman, Valgerdur M., Hardarson, Gudmundur A., Palsdottir, Ebba, Helgason, Agnar, Sigurjonsdottir, Runa, Sverrisson, Jon T., Kostulas, Konstantinos, Ng, Maggie C. Y., Baum, Larry, So, Wing Yee, Wong, Ka Sing, Chan, Juliana C. N., Furie, Karen L., Greenberg, Steven M., Sale, Michelle, Kelly, Peter, MacRae, Calum A., Smith, Eric E., Rosand, Jonathan, Hillert, Jan, Ma, Ronald C. W., Ellinor, Patrick T., Thorgeirsson, Gudmundur, Gulcher, Jeffrey R., Kong, Augustine, Thorsteinsdottir, Unnur, and Stefansson, Kari

Published
2007
Full Text
View/download PDF

4. Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes

Author

Pulit, Sara L., Weng, Lu-Chen, McArdle, Patrick F, Trinquart, Ludovic, Choi, Seung Hoan, Mitchell, Braxton D., Rosand, Jonathan, de Bakker, Paul I W, Benjamin, Emelia J, Ellinor, Patrick T, Kittner, Steven J, Lubitz, Steven A, Anderson, Christopher D, Christophersen, Ingrid E., Rienstra, Michiel, Roselli, Carolina, Yin, Xiaoyan, Geelhoed, Bastiaan, Barnard, John, Lin, Honghuang, Arking, Dan E., Smith, Albert V., Albert, Christine M., Chaffin, Mark, Tucker, Nathan R., Li, Molong, Klarin, Derek, Bihlmeyer, Nathan A, Low, Siew-Kee, Weeke, Peter E., Müller-Nurasyid, Martina, Smith, J. Gustav, Brody, Jennifer A., Niemeijer, Maartje N., Dörr, Marcus, Trompet, Stella, Huffman, Jennifer, Gustafsson, Stefan, Schurmann, Claudia, Kleber, Marcus E., Lyytikäinen, Leo-Pekka, Seppälä, Ilkka, Malik, Rainer, Horimoto, Andrea R. V. R., Perez, Marco, Sinisalo, Juha, Aeschbacher, Stefanie, Thériault, Sébastien, Yao, Jie, Radmanesh, Farid, Weiss, Stefan, Teumer, Alexander, Clauss, Sebastian, Deo, Rajat, Rader, Daniel J., Shah, Svati, Siland, Joylene E., Kubo, Michiaki, Smith, Jonathan D., Van Wagoner, David R., Bis, Joshua C., Perz, Siegfried, Psaty, Bruce M., Ridker, Paul M., Magnani, Jared W., Harris, Tamara B., Launer, Lenore J., Shoemaker, M. Benjamin, Padmanabhan, Sandosh, Haessler, Jeffrey, Bartz, Traci M., Waldenberger, Melanie, Lichtner, Peter, Arendt, Marina, Krieger, Jose E., Kähönen, Mika, Risch, Lorenz, Mansur, Alfredo J., Peters, Annette, Smith, Blair H., Lind, Lars, Scott, Stuart A., Lu, Yingchang, Bottinger, Erwin B., Hernesniemi, Jussi, Lindgren, Cecilia M., Wong, Jorge A, Huang, Jie, Eskola, Markku, Morris, Andrew P., Ford, Ian, Reiner, Alex P., Delgado, Graciela, Chen, Lin Y., Chen, Yii-Der Ida, Sandhu, Roopinder K., Li, Man, Boerwinkle, Eric, Eisele, Lewin, Lannfelt, Lars, Rost, Natalia, Orho-Melander, arju, Hamsten, Anders, Heeringa, Jan, Denny, Joshua C., Kriebel, Jennifer, Darbar, Dawood, Newton-Cheh, Christopher, Shaffer, Christian, Macfarlane, Peter W., Heilmann, Stefanie, Almgren, Peter, Huang, Paul L., Sotoodehnia, Nona, Soliman, Elsayed Z., Uitterlinden, Andre G., Hofman, Albert, Franco, Oscar H., Völker, Uwe, Jöckel, Karl-Heinz, Sinner, Moritz F., Lin, Henry J., Guo, Xiuqing, Dichgans, Martin, Ingelsson, Erik, Kooperberg, Charles, Melander, Olle, Loos, Ruth J. F., Laurikka, Jari, Conen, David, Harst, Pim van der, Lokki, Marja-Liisa, Kathiresan, Sekar, Pereira, Alexandre, Jukema, J. Wouter, Hayward, Caroline, Rotter, Jerome I., März, Winfried, Lehtimäki, Terho, Stricker, Bruno H., Chung, Mina K., Felix, Stephan B., Gudnason, Vilmundur, Alonso, Alvaro, Roden, Dan M., Sun, Albert, Anderson, Christopher D., Kääb, Stefan, Hopewell, Jemma C., Debette, Stephanie, Chauhan, Ganesh, Yang, Qiong, Worrall, Bradford B., Paré, Guillaume, Kamatani, Yoichiro, Hagemeijer, Yanick P., Verweij, Niek, Taylor, Kent D., Campbell, Archie, Magnusson, Patrik K., Porteous, David, Hocking, Lynne J., Vlachopoulou, Efthymia, Pedersen, Nancy L., Nikus, Kjell, Chasman, Daniel I., Heckbert, Susan R., Benjamin, Emelia J., Tanaka, Toshihiro, Lunetta, Kathryn L., Lubitz, Steven A., Ellinor, Patrick T., Smoller, Sylvia, Sorkin, John, Wang, Xingwu, Selim, Magdy, Pikula, Aleksandra, Wolf, Philip, Seshadri, Sudha, Bakker, Paul de, Chasman, Daniel, Rexrode, Kathryn, Chen, Ida, Rotter, Jerome, Luke, May, Sale, Michelle, Lee, Tsong-Hai, Chang, Ku-Chou, Elkind, Mitchell, Goldstein, Larry, James, Michael Luke, Breteler, Monique, O’Donnell, Chris, Leys, Didier, Carty, Cara, Kidwell, Chelsea, Olesen, Jes, Sharma, Pankaj, Rich, Stephen, Tatlisumak, Turgot, Happola, Olli, Bijlenga, Philippe, Soriano, Carolina, Giralt, Eva, Roquer, Jaume, Jimenez-Conde, Jordi, Cotlarcius, Ioana, Hardy, John, Korostynski, Michal, Boncoraglio, Giorgio, Ballabio, Elena, Parati, Eugenio, Mateusz, Adamski, Urbanik, Andrzej, Dziedzic, Tomasz, Jagiella, Jeremiasz, Gasowski, Jerzy, Wnuk, Marcin, Olszanecki, Rafael, Pera, Joanna, Slowik, Agnieszka, Juchniewicz, Karol Jozef, Levi, Christopher, Nyquist, Paul, Cendes, Iscia, Cabral, Norberto, Franca, Paulo, Goncalves, Anderson, Keller, Lina, Crisby, Milita, Kostulas, Konstantinos, Lemmens, Robin, Ahmadi, Kourosh, Opherk, Christian, Duering, Marco, Gonik, Mariya, Staals, Julie, Burri, Philippe, Sadr-Nabavi, Ariane, Romero, Javier, Biffi, Alessandro, Anderson, Chris, Falcone, Guido, Brouwers, Bart, Du, Rose, Kourkoulis, Christina, Battey, Thomas, Lubitz, Steven, Mueller-Myhsok, Bertram, Meschia, James, Brott, Thomas, Pare, Guillaume, Pichler, Alexander, Enzinger, Christian, Schmidt, Helena, Schmidt, Reinhold, Seiler, Stephan, Blanton, Susan, Yamada, Yoshiji, Bersano, Anna, Rundek, Tatjana, Sacco, Ralph, Chan, Yu-Feng Yvonne, Gschwendtner, Andreas, Deng, Zhen, Barr, Taura, Gwinn, Katrina, Corriveau, Roderick, Singleton, Andrew, Waddy, Salina, Launer, Lenore, Chen, Christopher, Le, Kim En, Lee, Wei Ling, Tan, Eng King, Olugbodi, Akintomi, Rothwell, Peter, Schilling, Sabrina, Mok, Vincent, Lebedeva, Elena, Jern, Christina, Jood, Katarina, Olsson, Sandra, Kim, Helen, Lee, Chaeyoung, Kilarski, Laura, Markus, Hugh, Peycke, Jennifer, Bevan, Steve, Sheu, Wayne, Chiou, Hung Yi, Chern, Joseph, Giraldo, Elias, Taqi, Muhammad, Jain, Vivek, Lam, Olivia, Howard, George, Woo, Daniel, Kittner, Steven, Mitchell, Braxton, Cole, John, O’Connell, Jeff, Milewicz, Dianna, Illoh, Kachikwu, Worrall, Bradford, Stine, Colin, Karaszewski, Bartosz, Werring, David, Sofat, Reecha, Smalley, June, Lindgren, Arne, Hansen, Bjorn, Norrving, Bo, Smith, Gustav, Martin, Juan Jose, Thijs, Vincent, Klijn, Karin, van’t Hof, Femke, Algra, Ale, Macleod, Mary, Perry, Rodney, Arnett, Donna, Pezzini, Alessandro, Padovani, Alessandro, Cramer, Steve, Fisher, Mark, Saleheen, Danish, Broderick, Joseph, Kissela, Brett, Doney, Alex, Cathie, Sudlow, Rannikmae, Kristiina, Silliman, Scott, McDonough, Caitrin, Walters, Matthew, Pedersen, Annie, Nakagawa, Kazuma, Chang, Christy, Dobbins, Mark, McArdle, Patrick, Chang, Yu-Ching, Brown, Robert, Brown, Devin, Holliday, Elizabeth, Kalaria, Raj, Maguire, Jane, John, Attia, Farrall, Martin, Giese, Anne-Katrin, Fornage, Myriam, Majersik, Jennifer, Cushman, Mary, Keene, Keith, Bennett, Siiri, Tirschwell, David, Psaty, Bruce, Reiner, Alex, Longstreth, Will, Spence, David, Montaner, Joan, Fernandez-Cadenas, Israel, Langefeld, Carl, Bushnell, Cheryl, Heitsch, Laura, Lee, Jin-Moo, Sheth, Kevin, Cardiovascular Centre (CVC), Department of Medicine, Clinicum, Transplantation Laboratory, Medicum, Neurologian yksikkö, Department of Neurosciences, University of Helsinki, Doctoral Programme in Clinical Research, HUS Neurocenter, Epidemiology, Internal Medicine, Klinische Neurowetenschappen, RS: CARIM - R3.03 - Cerebral small vessel disease, and MUMC+: MA Med Staf Spec Neurologie (9)

Subjects
Medizin, 030204 cardiovascular system & hematology, VARIANTS, 3124 Neurology and psychiatry, 0302 clinical medicine, Epidemiology, Genotype, EPIDEMIOLOGY, Stroke, Genetics (clinical), 0303 health sciences, Aspirin, Atrial fibrillation, ASSOCIATION, 3. Good health, LIFETIME RISK, ISCHEMIC-STROKE, Cardiology, Biomarker (medicine), Medical genetics, BURDEN, Medical Genetics, Life Sciences & Biomedicine, medicine.drug, medicine.medical_specialty, Clinical Neurology, Single-nucleotide polymorphism, Article, 03 medical and health sciences, Internal medicine, Genetic predisposition, medicine, SNP, cardiovascular diseases, Genotyping, 030304 developmental biology, Genetic association, Medicinsk genetik, Science & Technology, business.industry, 3112 Neurosciences, Heritability, medicine.disease, PREVENTION, ASPIRIN, Neurology (clinical), Neurosciences & Neurology, business, 030217 neurology & neurosurgery, CAUSATIVE CLASSIFICATION
Abstract

ObjectiveWe sought to assess whether genetic risk factors for atrial fibrillation (AF) can explain cardioembolic stroke risk.MethodsWe evaluated genetic correlations between a previous genetic study of AF and AF in the presence of cardioembolic stroke using genome-wide genotypes from the Stroke Genetics Network (N = 3,190 AF cases, 3,000 cardioembolic stroke cases, and 28,026 referents). We tested whether a previously validated AF polygenic risk score (PRS) associated with cardioembolic and other stroke subtypes after accounting for AF clinical risk factors.ResultsWe observed a strong correlation between previously reported genetic risk for AF, AF in the presence of stroke, and cardioembolic stroke (Pearson r = 0.77 and 0.76, respectively, across SNPs with p < 4.4 × 10−4 in the previous AF meta-analysis). An AF PRS, adjusted for clinical AF risk factors, was associated with cardioembolic stroke (odds ratio [OR] per SD = 1.40, p = 1.45 × 10−48), explaining ∼20% of the heritable component of cardioembolic stroke risk. The AF PRS was also associated with stroke of undetermined cause (OR per SD = 1.07, p = 0.004), but no other primary stroke subtypes (all p > 0.1).ConclusionsGenetic risk of AF is associated with cardioembolic stroke, independent of clinical risk factors. Studies are warranted to determine whether AF genetic risk can serve as a biomarker for strokes caused by AF.

Published
2018

5. The New York Times Daily Lesson Plan: Animal Fact or Fiction

Author

Kahn, Javaid, Sale, Michelle, Kahn, Javaid, and Sale, Michelle

Abstract

Animals have long captured the human imagination, and it is not always easy to decipher animal fact from fiction. This intriguing lesson plan challenges students to analyze information about animals more closely, conduct research, and write about an animal as well. Designed for grades 6-12, the one-hour lesson was authored by Michelle Sale (of The New York Times Learning Network) and Javaid Khan (of The Bank Street College of Education in New York City). The website includes a lesson description; a list of Academic Content Standards; and concise sections that address objectives, materials, extension activities, evaluation, and more.

Published
2004

6. Mutations in a Large Cohort of Young Adult Patients with Core Binding Factor Acute Myeloid Leukemia: Impact on Outcome and the Selection of Patients for Alternative Treatment Including Transplantation in First Complete Remission

Author

Allen, Christopher G, primary, Hills, Robert K, additional, Evans, Catherine M, additional, Lamb, Katarina, additional, Sellar, Rob, additional, Moorman, Anthony V, additional, Sale, Michelle, additional, Liu-Yin, John Ahman, additional, Burnett, Alan K, additional, Linch, David C, additional, and Gale, Rosemary E, additional

Published
2011
Full Text
View/download PDF

9. Surgery Partners explores potential sale, Bloomberg reports

Subjects
Bain Capital L.L.C., Business, News, opinion and commentary
Abstract

Surgery Partners, supported by Bain Capital, is considering various options, including a potential sale, Michelle Davis and Ryan Gould of Bloomberg reported, citing sources familiar with the situation. The company [...]

Published
2024

10. Clark County to put Tri-Mountain Golf Course in Ridgefield on the market

Subjects
County councils, Business, General interest, Business, regional
Abstract

Byline: Shari Phiel Sep. 13Clark County is putting Tri-Mountain Golf Course up for sale. Michelle Schuster, director of internal services for the county, said the request for bids will go [...]

Published
2024

12. Predictive Value of Minimal Residual Disease (MRD) Monitoring by RQ-PCR in WT1Positive Patients Entered in the UK MRC AML-15 Trial

Author

Liu-Yin, John, Sale, Michelle, Daly, Sarah, Hills, Robert, Wheatley, Keith, and Burnett, Alan K.

Abstract

Relapse remains the main cause of treatment failure in Acute Myeloid Leukaemia (AML). Some 65% of AML patients lack a specific fusion transcript which can serve as a molecular target for detecting residual disease. However, in over 75% of AML cases, the Wilm's Tumor (WT1) gene is over-expressed and can therefore be used for MRD monitoring by RQ-PCR. The clinical value of serial MRD monitoring in WT1positive patients was prospectively assessed in the AML-15 Trial which opened in 2002. The trial compared 3 induction regimens (DA v/sADE v/sFLAG Ida), followed by randomisation in consolidation (courses 3 and 4) to either MACE + MidAC or 2 doses of Ara-C (3g/m2or 1.5g/m2) and to stop or have a 5thcourse (Ara-C 1.5g/m2). Patients were also randomised to receive Gemtuzumab Ozogamicin (3mg/m2) at induction and/or consolidation. Adults in the standard and poor risk groups were scheduled to receive an allograft if a matched donor was available. An “in house” WT1assay used primers/probes covering exons 7 and 8 in the 3′ region of the WT1gene. WT1transcripts from BM and PB were measured by real-time quantitative PCR (RQ-PCR) on the 7900 HT ABI machine, at diagnosis, after each course of chemotherapy, stem cell transplant, and during remission for up to 3 years. WT1copies were normalised to ABLgene and expressed per 105ABLcopies. WT1was over-expressed in >80% of AML cases screened, when compared to normal BM copies (median 544, range 31–1173), PB (median 10, r 0–58), PBSC (median 71, r 0–483). In this study, 700 patients (excluding Core Binding Factor positive AML) with diagnostic BM WT1levels >104copies have been recruited and data on 416 are presented. Follow up is complete to 1/1/08 with 244 relapses after a median follow-up of 40 months. At complete remission (CR) following induction, a greater log reduction in WT1transcripts was associated with a significantly reduced relapse risk even after adjustment for age, WBC, cytogenetics, performance status and de Novo/Secondary AML (hazard ratio (HR) 0.57 (0.46–0.71) per log reduction p<0.0001). The 5yr relapse rates (RR) for patients with a log reduction of <2, 2–3, and 3 or more were 77%, 50% and 26% respectively (p <0.00001). Furthermore, presence or absence of a 2 log reduction adds to the MRC risk index (developed to identify patients who might benefit from transplant or be candidates for experimental therapies, Burnett et al. ASH 2006, Abstract 18) for survival from CR (HR 0.59 (0.37–0.91), p=0.02). With respect to post induction WT1transcripts, there were naturally three groups for both BM and PB levels for relapse risk: <1000, 1000–4999, 5000+ copies for BM (5 yr RR 45%, 74%, 82%, p<0.0001 ) and <1000, 1000–2999 and 3000+ copies for PB (5yr RR 53%, 82%, 91%, p<0.0001). After consolidation/SCT, BM and PB transcript levels were also highly predictive of relapse: BM <5000 copies RR 37%, BM 5000+ copies RR 84% (p<0.0001); PB <1000 copies RR 32%, PB 1000+ copies RR 90% (p<0.0001). Looking at all data together, in a multivariate analysis adjusted for MRC risk group, the most important prognostic variables for relapse, relapse free survival and overall survival were post induction log reduction and post chemotherapy PB transcript level >500 copies. In all cases PB transcript levels were more prognostic than levels from BM. We conclude that MRD monitoring in WT1positive AML patients allows risk stratification based on treatment response, and in this group of patients, MRD monitoring adds to already known risk factors. Whether patients identified as being at high risk of relapse benefit from further treatment, including allogeneic stem cell transplantation, remains to be determined in future studies.

Published
2008
Full Text
View/download PDF

13. Counseling on Access to Lethal Means (CALM): An Evaluation of a Suicide Prevention Means Restriction Training Program for Mental Health Providers.

Author

Sale, Elizabeth, Hendricks, Michelle, Weil, Virginia, Miller, Collin, Perkins, Scott, and McCudden, Suzanne

Subjects
SUICIDE prevention, MENTAL health personnel, EVALUATION of human services programs, CONFIDENCE, COUNSELING, SELF-efficacy, SUICIDE, EVALUATION research, EDUCATION
Abstract

This paper evaluates the effectiveness of the Counseling on Access to Lethal Means (CALM) suicide prevention program. CALM trains mental health providers how to counsel suicidal individuals and those who support them on mean restriction during times of crisis. Pre/post/3-month follow-up assessments measured knowledge of lethal means, confidence and comfort in discussing means restriction (self-efficacy), and future intentions to counsel clients on means restriction. Change in the number of clients receiving lethal means counseling was also assessed. All constructs increased significantly at posttest. Confidence and counseling intentions were sustained at follow-up and significantly more clients received means counseling in the 3 months following the CALM training. Knowledge and comfort levels decreased at follow-up but not to pre-training levels. CALM is effective at increasing mental health professionals’ comfort, knowledge, and frequency of talking about means restriction with clients. an effective means restriction training program. A template to assess clients for suicidality and lethal means access and booster sessions are recommended to further sustain effects. [ABSTRACT FROM AUTHOR]

Published
2018
Full Text
View/download PDF

16. Friday Highlights.

Author

COOPER, MANDY, BULLIMORE, EMMA, CLARK, CAREN, PIZEY, NIGEL, LOWLES, JOANNE, MORRISSEY, STEVE, PATRICK, LISA, WALSH, FIONA, EWENS, JUDY, MARLAND, SEAN, CANNON, NICHOLAS, REILLY, ELAINE, and DAVIES, HANNAH

Published
2018

20. Homes gossip.

Author

Amira Hashish

Abstract

Bra queen Michelle's £1.5m sale ? MICHELLE MONE is settling into a new three-bedroom townhouse in her native Scotland. The Ultimo lingerie boss splashed out £780,700 on the duplex in an upmarket area of Glasgow after her split from husband Michael, 46. [ABSTRACT FROM PUBLISHER]

Published
2013

21. DISPATCHES.

Subjects
POSTAL savings banks, IMMIGRANTS
Published
2019

25. In the News.

Subjects
STATISTICS, CONGREGATE housing, 401(K) plans, MEDICARE
Abstract

The article presents statistics related to the consumer debt industry in the U.S., as of July 1, 2009 including the average monthly cost for an assisted living community in 2008, the median rate of return for 401(k) plans in 2008, and the projected total amount of Medicare benefit payments in 2009.

Published
2009

26. Appreciation to Reviewers.

Subjects
DEDICATIONS
Abstract

People who the author would like to thank in the creation of the journal "The Journal of Behavioral Health Services and Research," are mentioned.

Published
2008
Full Text
View/download PDF

30. PARIS' NEW CELL.

Author

Wulff, Jennifer, Perry, Beth, Lee, Ken, Harrington, Maureen, Breuer, Howard, Naff, Lycia, Lansing, Kimberly, Alexander, Bryan, and Lewis-Boothman, Debra

Subjects
PRISON sentences, DRUNK driving, PROBATION, ACTIONS & defenses (Law)
Abstract

This article reports on media personality Paris Hilton's being sentenced to 45 days in prison. After being arrested for driving under the influence in September 2006, Hilton committed several driving infractions and violated her probation, forcing Judge Michael T. Sauer to sentence her to jail. Hilton claims her publicist Elliot Mintz gave her misinformation about her driving privileges, and her lawyers have appealed the ruling. INSETS: WHAT PARIS DID WRONG;IT'S NOT THE HILTON;WHO'S THE JUDGE?;WOMEN BEHIND BARS

Published
2007

33. Keys Steps to Prepare Your Practice for Sale.

Author

Stephenson, Michelle

Subjects
OPHTHALMOLOGY practice, MEDICAL offices, PROFIT, MANAGEMENT
Abstract

The article focuses on various factors and strategies to consider when planning to sell an ophthalmology practice. According to the author, one priorities in planning is to maximize the profit of a practice. Amy Galloway, director at Tripp Scott PA, says that one way of optimizing a practice's profit is through having better reimbursement rates. The author adds another factor to consider is to improve a practice's curb appeal.

Published
2011

34. Homes gossip

Subjects
Business, General interest
Abstract

Byline: Amira Hashish Bra queen Michelle's £1.5m sale ? MICHELLE MONE is settling into a new three-bedroom townhouse in her native Scotland. The Ultimo lingerie boss splashed out £780,700 on [...]

Published
2013

36. Short Sale, Long Process.

Subjects
SHORT sales (Real property), REAL property sales & prices, MORTGAGES
Abstract

An interview with real estate agent Jeff Yarbrough is presented which focuses on short sales. Asked whom short sales benefit, he says that sellers benefit because they are able to exit from a mortgage they cannot afford or do not wish to continue. He says short sales typically end up at about the market price, so buyers do not generally get an unusually inexpensive home. He notes that short sales often take a long time to complete.

Published
2012

37. What an Outrage.

Author

Diament, Michelle

Subjects
REBATES, SUBSCRIPTIONS to serial publications
Abstract

The article features Michael Grantham of Tallahassee, Florida who is having a difficulty getting magazine refunds as of July 2009 following his late father's subscription to "TV Guide" through October 2017 and "U.S. News & World Report" through July 2023.

Published
2009

38. Could High Medical Bills Trigger Firing?

Author

Diament, Michelle

Subjects
DISMISSAL of employees, MEDICAL care costs
Abstract

The article features Phillis Dewitt who lost her job as a nurse manager at Proctor Hospital in Peoria, Illinois due to her late husband's high medical bills.

Published
2009

40. Budget cooking.

Subjects
BUDGET, COOKING, GROCERY shopping, MEAT, HOME economics
Abstract

The article presents advice on budget cooking. It includes the need to create a meal plan for a week, the use of meat-alternative protein sources such as tofu and tempeh and buying a home-brand quality for items like flour, pasta, sugar and rice.

Published
2006

42. Don't play chicken.

Subjects
CONSUMER protection, CAMPYLOBACTER infections, FOOD contamination, FOOD safety, POULTRY
Abstract

The article discusses consumer safety concerns and technological solutions developed to address campylobacter contamination in poultry in the British market. Topics explored include the statement issued by Karen Middleton-Gell of the Society of Food Hygiene and Technology regarding cross-contamination, the implementation of stricter food safety regulations by the British Food Standards Agency (FSA), and the increase in consumer awareness of said bacterial contamination.

Published
2015

43. Going Green Could Add Plenty of Green to Investors'Wallets.

Author

Wiedemann, Liz

Subjects
CONFERENCES & conventions, ENVIRONMENTALISM, ENVIRONMENTAL protection conferences, RENEWABLE energy sources conferences, GREEN movement
Abstract

Information about the topics discussed during the panel discussion hosted by Envision Solar as part of the first Green Leaders Week in La Jolla, San Diego, California on July 22, 2008 is presented. The discussion was aimed at educating potential investors about renewable energy. Bob Noble, chairman and chief executive officer (CEO) of Envision, said that the way Californians use, produce and distribute energy is changing.

Published
2008

45. WEEKIN review.

Author

Wiedemann, Liz

Subjects
BUSINESS enterprises, CORPORATE growth, BUSINESS planning
Abstract

The article offers business news briefs in San Diego, California. Island Data Corp., a Carlsbad-based provider of text analytics software, relocated its sales, marketing and executive headquarters to San Francisco. San Diego-based Illumina Inc. plans to acquire Avantome Inc. to secure its position as leader of genetic sequencing technologies. Cubic Corp. has terminated 105 employees and five corporate executives from its defense division to streamline its operation.

Published
2008

46. Ex-Regent Inns sites up for sale.

Author

Perrett, Michelle

Subjects
ENGLAND, REGENT Inns PLC
Abstract

The article reports that former Regent Inns sites have been put on sales in England.

Published
2010

47. Properties of the week.

Subjects
REAL property, HOTELS
Abstract

The article offers information on real estate properties which includes the Globe Hotel located at Great Torrington in North Devon, England, Loudoun Hill Inn in Scotland and Plough & Harrow hotel in Kent, England.

Published
2010

48. GENERAL OBLIGATION YIELD CURVES FOR FEB. 4, 2010.

Subjects
CHARTS, diagrams, etc., BONDS (Finance)
Abstract

A chart is presented depicting the general obligation bond yield curves for February 4, 2010 in the Northeastern states including Delaware, Maryland and Pennsylvania.

Published
2010

49. VISIBLE SUPPLY BY STATE.

Subjects
CHARTS, diagrams, etc., BONDS (Finance)
Abstract

A chart is presented depicting the visible supply of bonds by states in the U.S. including Connecticut, Maine and New Jersey.

Published
2010

50. Tax Receipts Beat Estimate.

Author

Kaske, Michelle

Subjects
INTERNAL revenue
Abstract

The article reports that Puerto Rico's fiscal 2010 tax revenues collected 3.4 billion U.S. dollars of tax receipts from July to December 2009.

Published
2010

Catalog

Books, media, physical & digital resources
See catalog results