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2. “I’d like more options!”: Interviews to explore young people and family decision-making needs for pain management in juvenile idiopathic arthritis

Author

Toupin-April, Karine, Gaboury, Isabelle, Proulx, Laurie, Huber, Adam M., Duffy, Ciarán M., Morgan, Esi M., Li, Linda C., Stringer, Elizabeth, Connelly, Mark, Weiss, Jennifer E., Gibbon, Michele, Sachs, Hannah, Sivakumar, Aditi, Sirois, Alexandra, Sirotich, Emily, Trehan, Natasha, Abrahams, Naomi, Cohen, Janice S., Cavallo, Sabrina, Hindi, Tania El, Ragusa, Marco, Légaré, France, Brinkman, William B., Fortin, Paul R., Décary, Simon, Lee, Rebecca, Gmuca, Sabrina, Paterson, Gail, Tugwell, Peter, and Stinson, Jennifer N.

Published
2023
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5. Antithrombotic Management and Outcomes of Anterior ST-Elevation Myocardial Infarction With New-Onset Wall Motion Abnormalities in Men and Women

Author

Boivin-Proulx, Laurie-Anne, Ieroncig, Fabrice, Demers, Simon-Pierre, Nozza, Anna, Soltani, Marwa, Ghersi, Ismahane, Verreault-Julien, Louis, Alansari, Yahya, Massie, Charles, Simard, Philippe, Rosca, Lorena, Lalancette, Jean-Simon, Massicotte, Gabriel, Chen-Tournoux, Annabel, Daneault, Benoit, Paradis, Jean-Michel, Diodati, Jean G., Pranno, Nicolas, Jolicoeur, Marc, Potter, Brian J., Marquis-Gravel, Guillaume, and Pacheco, Christine

Published
2024
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6. Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology 2023 Focused Update of the Guidelines for the Use of Antiplatelet Therapy

Author

Bainey, Kevin R., Marquis-Gravel, Guillaume, Belley-Côté, Emilie, Turgeon, Ricky D., Ackman, Margaret L., Babadagli, Hazal E., Bewick, David, Boivin-Proulx, Laurie-Anne, Cantor, Warren J., Fremes, Stephen E., Graham, Michelle M., Lordkipanidzé, Marie, Madan, Mina, Mansour, Samer, Mehta, Shamir R., Potter, Brian J., Shavadia, Jay, So, Derek F., Tanguay, Jean-François, Welsh, Robert C., Yan, Andrew T., Bagai, Akshay, Bagur, Rodrigo, Bucci, Claudia, Elbarouni, Basem, Geller, Carol, Lavoie, Andrea, Lawler, Patrick, Liu, Shuangbo, Mancini, John, and Wong, Graham C.

Published
2024
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7. The Canadian Women’s Heart Health Alliance ATLAS on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women — Chapter 9: Summary of Current Status, Challenges, Opportunities, and Recommendations

Author

Mulvagh, Sharon L., Colella, Tracey J.F., Gulati, Martha, Crosier, Rebecca, Allana, Saleema, Randhawa, Varinder Kaur, Bruneau, Jill, Pacheco, Christine, Jaffer, Shahin, Cotie, Lisa, Mensour, Emma, Clavel, Marie-Annick, Hill, Braeden, Kirkham, Amy A., Foulds, Heather, Liblik, Kiera, Van Damme, Andrea, Grace, Sherry L., Bouchard, Karen, Tulloch, Heather, Robert, Helen, Pike, April, Benham, Jamie L., Tegg, Nicole, Parast, Nazli, Adreak, Najah, Boivin-Proulx, Laurie-Anne, Parry, Monica, Gomes, Zoya, Sarfi, Hope, Iwegim, Chinelo, Van Spall, Harriette G.C., Nerenberg, Kara A., Wright, Stephen P., Limbachia, Jayneelkumar A., Mullen, Kerri-Anne, and Norris, Colleen M.

Published
2024
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9. Contemporary incidence and predictors of left ventricular thrombus in patients with anterior acute myocardial infarction

Author

Boivin-Proulx, Laurie-Anne, Ieroncig, Fabrice, Demers, Simon-Pierre, Nozza, Anna, Soltani, Marwa, Ghersi, Ismahane, Verreault-Julien, Louis, Alansari, Yahya, Massie, Charles, Simard, Philippe, Rosca, Lorena, Lalancette, Jean-Simon, Massicotte, Gabriel, Chen-Tournoux, Annabel, Daneault, Benoit, Paradis, Jean-Michel, Diodati, Jean G., Pranno, Nicolas, Jolicoeur, Marc, Potter, Brian J., and Marquis-Gravel, Guillaume

Published
2023
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20. How Safe Are COVID-19 Vaccines in Individuals with Immune-Mediated Inflammatory Diseases? The SUCCEED Study.

Author

Tsyruk, Olga, Kaplan, Gilaad G., Fortin, Paul R., Hitchon, Carol A, Chandran, Vinod, Larché, Maggie J., Avina-Zubieta, Antonio, Boire, Gilles, Colmegna, Ines, Lacaille, Diane, Lalonde, Nadine, Proulx, Laurie, Richards, Dawn P., Boivin, Natalie, DeBow, Christopher, Kovalova-Wood, Lucy, Paleczny, Deborah, Wilhelm, Linda, Lukusa, Luck, and Pereira, Daniel

Subjects
BELL'S palsy, INFLAMMATORY bowel diseases, EMERGENCY room visits, VACCINE safety, PSORIATIC arthritis
Abstract

We were tasked by Canada's COVID-19 Immunity Task Force to describe severe adverse events (SAEs) associated with emergency department (ED) visits and/or hospitalizations in individuals with immune-mediated inflammatory diseases (IMIDs). At eight Canadian centres, data were collected from adults with rheumatoid arthritis (RA), axial spondyloarthritis (AxS), systemic lupus (SLE), psoriatic arthritis (PsA), and inflammatory bowel disease (IBD). We administered questionnaires, analyzing SAEs experienced within 31 days following SARS-CoV-2 vaccination. About two-thirds (63%) of 1556 participants were female; the mean age was 52.5 years. The BNT162b2 (Pfizer) vaccine was the most common, with mRNA-1273 (Moderna) being second. A total of 49% of participants had IBD, 27.4% had RA, 14.3% had PsA, 5.3% had SpA, and 4% had SLE. Twelve (0.77% of 1556 participants) SAEs leading to an ED visit or hospitalization were self-reported, occurring in 11 participants. SAEs included six (0.39% of 1556 participants) ED visits (including one due to Bell's Palsy 31 days after first vaccination) and six (0.39% of 1556 participants) hospitalizations (including one due to Guillain-Barré syndrome 15 days after the first vaccination). Two SAEs included pericarditis, one involved SLE (considered a serious disease flare), and one involved RA. Thus, in the 31 days after SARS-CoV-2 vaccination in our IMID sample, very few serious adverse events occurred. As SARS-CoV2 continues to be a common cause of death, our findings may help optimize vaccination acceptance. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Immediate effect of the COVID-19 pandemic on patient health, health-care use, and behaviours: results from an international survey of people with rheumatic diseases

Author

Robinson, Philip C., Bhana, Suleman, Liew, Jean W., Sufka, Paul H., Singh, Namrata, Howard, Richard A., Kim, Alfred H.J., Westrich-Robertson, Tiffany, Sirotich, Emily, Tsui, Edmund, Duarte-Garcia, Ali, Sparks, Jeffrey A., Tam, Herman, Jayatilleke, Arundathi, Konig, Maximilian F., Graef, Elizabeth R., Putman, Michael S., Syed, Reema H., Korsten, Peter, Mateus, Elsa, Sattui, Sebastian E., Wallace, Zachary S., Laura, Upton A., Adam, Kilian, Chock, Yu Pei Eugenia, White, Douglas W., Zamora, Geraldine T., Traboco, Lisa S., Patel, Aarat M., Grainger, Rebecca, Ugarte-Gil, Manuel F., Gianfrancesco, Milena A., Amigues, Isabelle, Sanchez-Alvarez, Catalina, Trupin, Laura, Jacobsohn, Lindsay R., Beesley, Richard P., Hoyer, Bimba F., Machado, Pedro M., Makan, Kavita, Gossec, Laure, Priyank, Chaudhary, Leipe, Jan, Wallace, Beth, Angeles-Han, Sheila T., Almaghlouth, Ibrahim A., Katherine, Wysham D., Padula, Anthony S., Berenbaum, Francis, Treemarcki, Erin M., Sinha, Rashmi, Lewandowski, Laura B., Webb, Kate, Young, Kristen J., Bulina, Inita, Herrera Uribe, Sebastian, Rubinstein, Tamar B., Nolan, Marc W., Ang, Elizabeth Y., Venuturupalli, Swamy R., Hausmann, Jonathan S., Dubreuil, Maureen, Pisoni, Cecilia N., Cosatti, Micaela A., Campos, Jose, Simard, Julia F., Conway, Richard, Peterson, Tiffany M., Harrison, Carly O., Felix, Christele, Richards, Dawn P., Proulx, Laurie, Akpabio, Akpabio A., Worthing, Angus B., Laidlaw, Lynn R., Reid, Pankti, Palmerlee, Candace A., Danila, Maria I., Sahar, Lotfi-Emran, Linh, Ngo Q., Agarwal, Arnav, Studenic, Paul, Liew, David F.L., Larche, Maggie J., Mingolla, Serena A.M., Zamora, Erick A., Angevare, Saskya S., Sinha, Rashmi R., Durrant, Karen L.W., Peirce, Andrea, Somers, Emily C., Cappelli, Laura C., Frankel, Brittany A., Kumar, Bharat, Silinsky Krupnikova, Sonia D., Rosario Vega, Jorge A., Frankovich, Jourdan, Fernandez-Ruiz, Ruth, Posada Velásquez, Marcela, Yeoh, Su-Ann, Marino, Maria, Nudel, Michal, Scott, Chrisiaan, Rodríguez, Cecilia, Martín Mancheño, Ana I., Seo, Philip, Gamboa-Cárdenas, Rocío V., Pimentel-Quiroz, Victor R., Reátegui-Sokolova, Cristina, Kihara, Mari, Lin, Chung M.A., Kattula, Dheera, Laila, Girgis, Carmona, Loreto, Wallace, John, Yazdany, Jinoos, Costello, Wendy, Gore-massy, Monique C., Tomasella, Laura-Ann, Kodek, Moré A., Hausmann, Jonathan S, Kennedy, Kevin, Simard, Julia F, Liew, Jean W, Sparks, Jeffrey A, Moni, Tarin T, Harrison, Carly, Larché, Maggie J, Levine, Mitchell, Sattui, Sebastian E, Semalulu, Teresa, Foster, Gary, Surangiwala, Salman, Thabane, Lehana, Beesley, Richard P, Durrant, Karen L, Mateus, Elsa F, Mingolla, Serena, Palmerlee, Candace A, Richards, Dawn P, Liew, David F L, Hill, Catherine L, Machado, Pedro M, Robinson, Philip C, Sufka, Paul, and Wallace, Zachary S

Published
2021
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29. Hyperventilation testing in the diagnosis of vasospastic angina: A clinical review and meta‐analysis.

Author

Boivin‐Proulx, Laurie‐Anne, Marquis‐Gravel, Guillaume, Rousseau‐Saine, Nicolas, Harel, François, Jolicoeur, E. Marc, and Pelletier‐Galarneau, Matthieu

Subjects
*CHEST pain, *ANGINA pectoris, *HYPERVENTILATION, *VENTRICULAR arrhythmia, *MYOCARDIAL perfusion imaging, *DIAGNOSIS
Abstract

Background: Given the limited access to invasive vasospastic reactivity testing in Western Countries, there is a need to further develop alternative non‐invasive diagnostic methods for vasospastic angina (VSA). Hyperventilation testing (HVT) is defined as a class IIa recommendation to diagnose VSA by the Japanese Society of Cardiology. Methods: In this systematic review and meta‐analysis reported according to the PRISMA statement, we review the mechanisms, methods, modalities and diagnostic accuracy of non‐invasive HVT for the diagnostic of VSA. Results: A total of 106 articles published between 1980 and 2022 about VSA and HVT were included in the systematic review, among which 16 were included in the meta‐analysis for diagnostic accuracy. Twelve electrocardiogram‐HVT studies including 804 patients showed a pooled sensitivity of 54% (95% confidence intervals [CI]; 30%–76%) and a pooled specificity of 99% (95% CI; 88%–100%). Four transthoracic echocardiography‐HVT studies including 197 patients revealed a pooled sensitivity of 90% (95% CI; 82%–94%) and a pooled specificity of 98% (95% CI; 86%–100%). Six myocardial perfusion imaging‐HVT studies including 112 patients yielded a pooled sensitivity of 95% (95% CI; 63%–100%) and a pooled specificity of 78% (95% CI; 19%–98%). Non‐invasive HVT resulted in a low rate of adverse events, ventricular arrhythmias being the most frequently reported, and were resolved with the administration of nitroglycerin. Conclusions: Non‐invasive HVT offers a safe alternative with high diagnostic accuracy to diagnose VSA in patients with otherwise undiagnosed causes of chest pain. [ABSTRACT FROM AUTHOR]

Published
2024
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34. 2023 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology Focused Update of the Guidelines for the Use of Antiplatelet Therapy

Author

Bainey, Kevin R., primary, Marquis-Gravel, Guillaume, additional, Belley-Côté, Emilie, additional, Turgeon, Ricky D., additional, Ackman, Margaret L., additional, Babadagli, Hazal E., additional, Bewick, David, additional, Boivin-Proulx, Laurie-Anne, additional, Cantor, Warren J., additional, Fremes, Stephen E., additional, Graham, Michelle M., additional, Lordkipanidzé, Marie, additional, Madan, Mina, additional, Mansour, Samer, additional, Mehta, Shamir R., additional, Potter, Brian J., additional, Shavadia, Jay, additional, So, Derek F., additional, Tanguay, Jean-François, additional, Welsh, Robert C., additional, Yan, Andrew T., additional, Bagai, Akshay, additional, Bagur, Rodrigo, additional, Bucci, Claudia, additional, Elbarouni, Basem, additional, Geller, Carol, additional, Lavoie, Andrea, additional, Lawler, Patrick, additional, Liu, Shuangbo, additional, Mancini, John, additional, and Wong, Graham C., additional

Published
2023
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35. Implementation of the Operating Room Black Box Research Program at the Ottawa Hospital Through Patient, Clinical, and Organizational Engagement: Case Study

Author

Boet, Sylvain, Etherington, Nicole, Lam, Sandy, Lê, Maxime, Proulx, Laurie, Britton, Meghan, Kenna, Julie, Przybylak-Brouillard, Antoine, Grimshaw, Jeremy, Grantcharov, Teodor, and Singh, Sukhbir

Subjects
Computer applications to medicine. Medical informatics, R858-859.7, Public aspects of medicine, RA1-1270
Abstract

BackgroundA large proportion of surgical patient harm is preventable; yet, our ability to systematically learn from these incidents and improve clinical practice remains limited. The Operating Room Black Box was developed to address the need for comprehensive assessments of clinical performance in the operating room. It captures synchronized audio, video, patient, and environmental clinical data in real time, which are subsequently analyzed by a combination of expert raters and software-based algorithms. Despite its significant potential to facilitate research and practice improvement, there are many potential implementation challenges at the institutional, clinician, and patient level. This paper summarizes our approach to implementation of the Operating Room Black Box at a large academic Canadian center. ObjectiveWe aimed to contribute to the development of evidence-based best practices for implementing innovative technology in the operating room for direct observation of the clinical performance by using the case of the Operating Room Black Box. Specifically, we outline the systematic approach to the Operating Room Black Box implementation undertaken at our center. MethodsOur implementation approach included seeking support from hospital leadership; building frontline support and a team of champions among patients, nurses, anesthesiologists, and surgeons; accounting for stakeholder perceptions using theory-informed qualitative interviews; engaging patients; and documenting the implementation process, including barriers and facilitators, using the consolidated framework for implementation research. ResultsDuring the 12-month implementation period, we conducted 23 stakeholder engagement activities with over 200 participants. We recruited 10 clinician champions representing nursing, anesthesia, and surgery. We formally interviewed 15 patients and 17 perioperative clinicians and identified key themes to include in an information campaign run as part of the implementation process. Two patient partners were engaged and advised on communications as well as grant and protocol development. Many anticipated and unanticipated challenges were encountered at all levels. Implementation was ultimately successful, with the Operating Room Black Box installed in August 2018, and data collection beginning shortly thereafter. ConclusionsThis paper represents the first step toward evidence-guided implementation of technologies for direct observation of performance for research and quality improvement in surgery. With technology increasingly being used in health care settings, the health care community should aim to optimize implementation processes in the best interest of health care professionals and patients.

Published
2021
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36. Predatory journals: no definition, no defence

Author

Grudniewicz, Agnes, Moher, David, Cobey, Kelly D., Bryson, Gregory L., Cukier, Samantha, Allen, Kristiann, Ardern, Clare, Balcom, Lesley, Barros, Tiago, Berger, Monica, Ciro, Jairo Buitrago, Cugusi, Lucia, Donaldson, Michael R., Egger, Matthias, Graham, Ian D., Hodgkinson, Matt, Khan, Karim M., Mabizela, Mahlubi, Manca, Andrea, Milzow, Katrin, Mouton, Johann, Muchenje, Marvelous, Olijhoek, Tom, Ommaya, Alexander, Patwardhan, Bhushan, Poff, Deborah, Proulx, Laurie, Rodger, Marc, Severin, Anna, Strinzel, Michaela, Sylos-Labini, Mauro, Tamblyn, Robyn, van Niekerk, Marthie, Wicherts, Jelte M., and Lalu, Manoj M.

Published
2019
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37. Canadian Rheumatology Association Living Guidelines for Rheumatoid Arthritis: Update #1

Author

Hazlewood, Glen S., primary, Akhavan, Pooneh, additional, Pardo, Jordi Pardo, additional, Agarwal, Arnav, additional, Schieir, Orit, additional, Barber, Claire E.H., additional, Proulx, Laurie, additional, Richards, Dawn P., additional, Bombardier, Claire, additional, Pope, Janet E., additional, Barnabe, Cheryl, additional, Tugwell, Peter, additional, Jamal, Shahin, additional, Thorne, J. Carter, additional, Nikolic, Roko P.A., additional, Khraishi, Majed, additional, Bansback, Nick, additional, Legge, Alexandra, additional, Bykerk, Vivian, additional, and Taylor-Gjevre, Regina, additional

Published
2023
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41. “I’d like more options!”: Interviews to explore young people and family decision-making needs for pain management in juvenile idiopathic arthritis

Author

April, Karine Toupin, primary, Gaboury, Isabelle, additional, Proulx, Laurie, additional, Huber, Adam M, additional, Duffy, Ciarán M, additional, Morgan, Esi M, additional, Li, Linda C, additional, Stringer, Elizabeth, additional, Connelly, Mark, additional, Weiss, Jennifer E, additional, Gibbon, Michele, additional, Sachs, Hannah, additional, Sivakumar, Aditi, additional, Sirois, Alexandra, additional, Sirotich, Emily, additional, Trehan, Natasha, additional, Abrahams, Naomi, additional, Cohen, Janice S, additional, Cavallo, Sabrina, additional, Hindi, Tania El, additional, Ragusa, Marco, additional, Légaré, France, additional, Brinkman, William B, additional, Fortin, Paul R, additional, Décary, Simon, additional, Lee, Rebecca, additional, Gmuca, Sabrina, additional, Paterson, Gail, additional, Tugwell, Peter, additional, and Stinson, Jennifer, additional

Published
2023
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44. Decision Aid–Led Tapering of Biologic and Targeted Synthetic Disease-Modifying Antirheumatic Drugs in Rheumatoid Arthritis: A Qualitative Study

Author

Lee, Jungyeon, Barber, Claire E.H., Jung, Michelle, Kaminska, Elzbieta, Bansback, Nick, Richards, Dawn, Proulx, Laurie, Rebutoc, Ann, and Hazlewood, Glen S.

Abstract

ObjectiveTo explore the experiences and perspectives of patients and rheumatologists on decision aid (DA)-led tapering of advanced therapy in rheumatoid arthritis (RA).MethodsSemistructured interviews were completed with patients and rheumatologists, embedded within a pilot study of DA-led tapering (ie, dose reduction) of biologic disease-modifying antirheumatic drugs (bDMARDs) and targeted synthetic DMARDs (tsDMARDs) in RA. All patients were in sustained (≥ 6 mos) remission and had chosen to reduce their therapy after a DA-led shared decision with their rheumatologist. The rheumatologists included those participating in the pilot (n = 4), and those who were not (n = 8). Reflexive thematic analysis of audiotaped and transcribed interviews identified themes in the group experiences.ResultsPatients (n = 10, 6 female) unanimously found the DA easy to understand and felt confident in shared decision making about treatment tapering and managing flares. Rheumatologists’ (n = 12, 5 female) perspectives on tapering bDMARDs and tsDMARDs varied widely, from very supportive to completely opposed, and influenced their views on the DA. Rheumatologists expressed concerns about patient comprehension, destabilizing a stable situation, risks of flare, and extending appointment times. Despite their initial reservations about sending the DA to all eligible patients ahead of appointments, 3 of 4 participating rheumatologists adopted this approach during the pilot, which had the benefit of facilitating patient-led conversations.ConclusionA DA-led strategy for tapering advanced therapy in RA was acceptable to patients and feasible in practice. Sending patients a DA ahead of their appointment facilitated patient-led conversations about tapering.

Published
2024
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45. Exploring perceptions of using preference elicitation methods to inform clinical trial design in rheumatology: A qualitative study and OMERACT collaboration

Author

Thomas, Megan, primary, Marshall, Deborah A., additional, Sanchez, Adalberto Loyola, additional, Bartlett, Susan J., additional, Boonen, Annelies, additional, Fraenkel, Liana, additional, Proulx, Laurie, additional, Voshaar, Marieke, additional, Bansback, Nick, additional, Buchbinder, Rachelle, additional, Guillemin, Francis, additional, Hiligsmann, Mickaël, additional, Richards, Dawn P., additional, Richards, Pamela, additional, Shea, Beverley, additional, Tugwell, Peter, additional, Falahee, Marie, additional, and Hazlewood, Glen S., additional

Published
2023
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46. Preferences for COVID-19 Vaccination in People With Chronic Immune-Mediated Inflammatory Diseases

Author

Hazlewood, Glen S., primary, Colmegna, Ines, additional, Hitchon, Carol, additional, Fortin, Paul R., additional, Bernatsky, Sasha, additional, Clarke, Ann E., additional, Mosher, Dianne, additional, Wilson, Todd, additional, Thomas, Megan, additional, Barber, Claire E.H., additional, Harrison, Mark, additional, Bansback, Nick, additional, Proulx, Laurie, additional, Richards, Dawn P., additional, and Kaplan, Gilaad G., additional

Published
2023
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47. Femoral Vascular Closure Devices and Bleeding, Hemostasis, and Ambulation Following Percutaneous Coronary Intervention

Author

Marquis‐Gravel, Guillaume, primary, Boivin‐Proulx, Laurie‐Anne, additional, Huang, Zhen, additional, Zelenkofske, Steven L., additional, Lincoff, A. Michael, additional, Mehran, Roxana, additional, Steg, P. Gabriel, additional, Bode, Christoph, additional, Alexander, John H., additional, and Povsic, Thomas J., additional

Published
2023
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49. Canadian Rheumatology Association Living Guidelines for Rheumatoid Arthritis: Update #2.

Author

Nikolic, Roko P. A., Pardo, Jordi Pardo, Pope, Janet E., Barber, Claire E. H., Barnabe, Cheryl, Schieir, Orit, Jamal, Shahin, Legge, Alexandra, Kuriya, Bindee, Akhavan, Pooneh, Thorne, J. Carter, Bombardier, Claire, Taylor-Gjevre, Regina, Bykerk, Vivian, Khraishi, Majed, Proulx, Laurie, Richards, Dawn P., Tugwell, Peter, Agarwal, Arnav, and Bansback, Nick

Published
2024
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