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29. Effects of SARS-CoV-2 emergency measures on high-risk lesions detection: a multicentre cross-sectional study

Author

Furnari, Manuele, Eusebi, Leonardo Henry, Savarino, Edoardo, Petruzzellis, Carlo, Esposito, Gianluca, Maida, Marcello, Ricciardiello, Luigi, Pecere, Silvia, Buda, Andrea, De Bona, Manuela, Spada, Cristiano, Di Giulio, Emilio, Costamagna, Guido, Boskoski, Ivo, Giannini, Edoardo, G, Angeletti, Stefano, Barbaro, Federico, Brunacci, Matteo, Cazzato, Maria, Corleto Vito, D, Demarzo, Maria G, Giambruno, Elisa, Morreale, Gaetano, Moscatelli, Alessandro, Pesenti, Mario, Polese, Lino, Risso, Davide, Tamanini, Giacomo, Zingone, Fabiana, Furnari, Manuele, Eusebi, Leonardo Henry, Savarino, Edoardo, Petruzzellis, Carlo, Esposito, Gianluca, Maida, Marcello, Ricciardiello, Luigi, Pecere, Silvia, Buda, Andrea, De Bona, Manuela, Spada, Cristiano, Di Giulio, Emilio, Costamagna, Guido, Boskoski, Ivo, and Giannini, Edoardo G

Subjects
0301 basic medicine, Pediatrics, medicine.medical_specialty, Delayed Diagnosis, Coronavirus disease 2019 (COVID-19), Cross-sectional study, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), gastrointestinal cancer, Digestive System Neoplasms, Time-to-Treatment, 03 medical and health sciences, 0302 clinical medicine, endoscopy, COVID-19, medicine, Humans, Retrospective Studies, Infection Control, medicine.diagnostic_test, business.industry, Settore MED/09 - MEDICINA INTERNA, Gastroenterology, Percentage reduction, Limiting, medicine.disease, Endoscopy News, Endoscopy, Cross-Sectional Studies, 030104 developmental biology, Italy, Dysplasia, 030211 gastroenterology & hepatology, Emergencies, business
Abstract

COVID-19 pandemic enforced the interruption of routine endoscopic examinations raising the issue of potential delays in the diagnosis of high-risk lesions. We conducted a multicentre study to assess the decrease of GI and pancreato-biliary high-risk lesions detection consequent to the reduction of the endoscopic activity. The lockdown period was compared to the equivalent timeframe of the previous 3 years. Endoscopic procedures decreased by 72.9% (elective 72.4% and urgent 51.3%); the overall cases of high-grade dysplasia/cancers decreased by 59.1% (23.4% pancreato-biliary cancers; 70.6% and 68.8% upper and lower GI lesions). The postemergency period should aim at limiting high-risk lesions delayed diagnoses. A multicentre, retrospective, cross-sectional study was performed in eight tertiary centres, representative of Northern and Southern Italy, to assess the decrease of GI and pancreato-biliary lesions detected, as a consequence of the reduction of endoscopic procedures caused by the COVID-19 pandemic restrictions. Five were academic centres (62.5%), and all working groups were involved in research activities and training programmes. We collected data from the pandemic lockdown period from 9 March to 4 May (11°−18° week) of 2020, referred as P2; and the equivalent prepandemic period (11°−18° week) of 2019, referred as P1. Data from the corresponding periods of the previous 2 years (2017 and 2018) were also collected in order to assess trends of the last 3 years. Main parameters analysed were: ### Endoscopic procedures The total number of endoscopic procedures performed at the eight centres in P1 was 13 293 (median 1912/centre; IQ 25th–75th: 1135–2691) procedures against 3799 (median 408/centre; IQ 25th–75th: 331–842) performed in P2, thus representing an overall reduction of 71.4% (details shown in figure 1). Figure 1 Percentage reduction of the global activities of the endoscopy units in P2 compared with P1. …

Published
2020
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43. A GASTROCOLIC FISTULA IN CROHNʼS DISEASE

Author

RUFFOLO, CESARE, ANGRIMAN, IMERIO, SCARPA, MARCO, DʼODORICO, ANNA, POLESE, LINO, BAROLLO, MICHELA, BERTIN, MATTEO, PAGANO, DUILIO, and DʼAMICO, DAVIDE F

Published
2005

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