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Abstract Background Dual-energy X-ray absorptiometry (DXA) is an important diagnostic test for bone mass status. The aim of this work was to set the standards for structured reporting of DXA measurements in adults within the context of fracture and fall risk assessment. Results Two rounds of Delphi were completed. The first Delphi round had a 68% response rate, while round two had a 100% response rate. After round 2, a total of 28 items were obtained, which were classified into three domains. The percentage of people who agreed with the recommendations (ranks 9–7) ranged from 76.5 to 100%. The wording of all 19 clinical standards determined by the scientific committee was agreed upon (i.e., 75% of respondents strongly agreed or agreed). Conclusion The DXA scan report is an independent document that contains sufficient information to enable optimal osteoporosis management advised by an experienced healthcare professional. Setting up quality standards for DXA scans not only supports healthcare professionals reporting/interpreting bone densitometry but also meets the parameters outlined in national as well as international guidelines or recommendations for the optimal management of osteoporosis and subsequent prevention of low trauma fractures.

Purpose : Platinum-based chemotherapies used to treat many types of cancers are ototoxic. Ototoxicity management (OtoM) to mitigate the ototoxic outcomes of cancer survivors is recommended practice yet it is not a standard part of oncologic care. Although more than 10,000 patients each year are treated with platinum-based chemotherapies at the US Veterans Health Administration (VA), the current state of OtoM in VA is not well-defined. This study reports on a national survey of VA audiologists' perceptions regarding OtoM in cancer patients. Methods: A 26-item online survey was administered to VA audiologists and service chiefs across the VA's 18 regional systems of care. Descriptive statistics and deductive thematic analysis were used to analyze the data. Results: The 61 respondents included at least one from each VA region. All reported they felt some form of OtoM was necessary for at-risk cancer patients. A pre-treatment baseline, the ability to detect ototoxicity early, and management of ototoxic effects both during and after treatment were considered high value objectives of OtoM by respondents. Roughly half reported routinely providing these services for patients receiving cisplatin and carboplatin. Respondents disagreed regarding appropriate hearing testing schedules and how to co-manage OtoM responsibilities with oncology. They identified barriers to care that conformed to three themes: care and referral coordination with oncology, audiology workload, and lack of protocols. Conclusions: Although VA audiologists value providing OtoM for cancer patients, only about half perform OtoM for highly ototoxic treatment regimens. The OtoMIC survey provides clinician perspectives to benchmark and address OtoM care gaps. Implications for cancer survivors: Collaboration between oncology and audiology is needed to improve current OtoM processes, so that cancer survivors can have more control over their long term hearing health. [ABSTRACT FROM AUTHOR]

Background: The most common sources of error in the preanalytical phase are considered to be at the stage of patient preparation and sample collection. In order to reduce the preanalytical errors, we aimed to determine the level of phlebotomists knowledge about the preanalytic phase before and after planned trainings in the study. Methods: Training about preanalytical processes was given to the 454 health professionals and the majority of them were employed as nurse. Questionnaires before and after training were conducted. In order to assess the effect of the training into the process, preanalytical error rates were calculated before and after training. Results: The total correct answer rates of vocational school of health diplomaed were statistically lower than the total correct answer rates of other. It was observed significantly increase in the rate of correct answers to questionnaire and significantly decrease in preanalytical error rates after training. Conclusions: The results of the survey showed that the attitudes of the phlebotomists were diverse in the preanalytical processes according to the levels of education and their practices. By providing training to all staff on a regular basis, their information about preanalytical phase could be updated and hence, it may possible to significantly reduce the preanalytical errors in health practice and nursing science. [ABSTRACT FROM AUTHOR]

Purpose: Ototoxic medications and chemical agents in the workplace can put individuals' hearing and vestibular health at risk for permanent injury. Proactive ototoxicity management (OtoM) strategies aim to minimize exposure, avoid onset of symptoms, provide ongoing monitoring, and manage auditory and vestibular changes as the clinical needs of the patient evolve. During a 2021 American Speech-Language-Hearing Association Special Interest Groups Open House, members of the International Ototoxicity Management Group discussed how best to integrate OtoM into routine clinical practice, what tools to use, and what special considerations need to be understood to best support patients and their families. Here, we have summarized their viewpoints to encourage widespread adoption of improved OtoM services for at-risk individuals. Conclusions: The field of audiology needs to move to a place where we better understand the full extent of ototoxicity and can agree on expanding minimum guidelines that can be implemented more universally to mitigate, detect, and manage the damage from ototoxic exposures. Only recently has our field seen a therapeutic drug that can protect against ototoxicity; however, the population served is restricted only to children receiving treatment for nonmetastatic carcinoma. This is hopefully just the beginning of future therapeutic interventions to come, but, in the meantime, ototoxicity resulting from other medications in different patient populations and chemical agents persists. [ABSTRACT FROM AUTHOR]

Purpose: The main objective of this study is to determine if there are domains of job performance and job stress that significantly influence work-life balance among COVID-19 Frontliners in Tagum City. Design/methodology/approach: This study used quantitative non-experimental research design utilizing correlational technique with a total sample size of 200 COVID-19 Frontliners selected through random sampling, data were collected through adopted survey questionnaire. The statistical tools used for data treatment in this study were mean, pearson-r and regression analysis. Findings: The result showed a very high level of job performance, moderate level of job stress, and high level of work-life balance among COVID-19 Frontliners. Also, there is a significant relationship between job performance and work-life balance, and between job stress and work-life balance. Practical implications: The domains of job performance and job stress that significantly predict work-life balance are task performance, having managerial responsibilities, and feeling poorly managed and resourced. Originality/value: This paper is an original work. Paper type: Research paper

Time is infinite movement in constant motion. We are glad to see that Neurorestoratology, a new discipline, has grown into a rich field involving many global researchers in recent years. In this 2019 yearbook of Neurorestoratology, we introduce the most recent advances and achievements in this field, including findings on the pathogenesis of neurological diseases, neurorestorative mechanisms, and clinical therapeutic achievements globally. Many patients have benefited from treatments involving cell therapies, neurostimulation/neuromodulation, brain–computer interface, neurorestorative surgery or pharmacy, and many others. Clinical physicians can refer to this yearbook with the latest knowledge and apply it to clinical practice.

Tujuan penelitian ini adalah untuk menguraikan geografis keadaan budaya hukum Suku Baduy Provinsi Banten, kemudian mengungkapkan secara cermat tentang budaya hukum perubahan kehidupan Masyarakat Baduy, juga menganalisis budaya hukum adat di Indonesia, menganalisis atas penyebab perubahan-perubahan hukum atas kehidupan kekerabatan Suku Baduy Provinsi Banten sebagai bagian suku Sunda di Provinsi Banten. Penelitian ini menggunakan metode yuridis normatif yang menganalisis secara kualitatif dengan menggunakan data sekunder yang berkaian dengan sistem budaya hukum Suku Baduy Provinsi Banten di Provinsi Banten. Hasil penelitian antara lain; dalam Kampung Suku Baduy masih berada bagian dari suku Sunda yang secara umum tidak terlalu banyak berbeda pada suku Sunda lainnya. Secara khusus yang membedakan Suku Baduy Provinsi Banten dengan suku Sunda lainnya adalah cara-cara berpakaian dan pelaksanaan tradisi sebagai bagian budaya hukum yang masih teguh memegang budaya hukumnya yang bersumber dari kebiasaan akar tradisi leluhur mereka yang masih dijaga baik. Budaya hukum terhadap perubahan berkehidupan masyarakat Masyarakat Baduy telah terikat tradisi adat perkawinan internal dan budaya hukum tradisi mereka yang mutlak dijaga secara murni. Budaya hukum atas berkehidupan hukum adat masih memproritaskan hukum adat dan hak ulayat yang hampir punah sebagaimana yang terjadi di beberapa daerah di Indonesia, ternyata Suku Baduy Provinsi Banten mampu mempertahankan eksistensinya dari pengaruh kemajuan bangsa. Perubahan tatanan budaya hukum Suku Baduy Provinsi Banten terhadap ronrongan pergaulan secara eksternal termasuk mengikuti pola-pola berprilaku pada masyarakat luar, termasuk penerimaan alat kemunikasi informasi seperti menonton televisi, juga menganjurkan sekolah kalangan muda sepanjang tidak merusak tatanan budaya hukum Suku Baduy Provinsi Banten yang mutlak harus dijaga keberadaan dan kelestariannya. Sedangkan dari sisi, sarananya Pemda Jawa Barat berkewajiban untuk mempertahankan budaya hukum masyarakat suku Sunda termasuk Suku Baduy Provinsi Banten dari ancaman kepunahan dan menyiapkan sarana dan prasarana untuk menjadi bagian tujuan wisata, karena tanpa dukungan pemerintah tidak maksimal mendatangkan devisa wisatawan yang datang secara individu.

Ali H Otom, M Rami Al-AhmarRheumatology and Rehabilitation Department, Royal Rehabilitation Centre, King Hussein Medical Centre, Amman, JordanBackground: The purpose of this study was to evaluate the pattern of bone loss and its consequences in a group of spinal cord injury (SCI) patients managed at the Spinal Unit-Royal Rehabilitation Centre, King Hussein Medical Centre, and its correlation with level and extent of injury, age, and time since injury.Methods: Bone mineral density (BMD) was measured by dual energy x-ray absorptiometry at the lumbar spine and femoral neck in a group of patients who had suffered an SCI a mean of 8.6 (range 1–31) years earlier and had completed their medical and rehabilitation program during the period July 2003 to December 2013. The patients were diagnosed to have osteoporosis according to World Health Organization criteria and their fracture risk was estimated from this score using published data. The severity of their spinal injuries ranged from class A to D according to American Spinal Injury Association criteria.Results: Of the 55 patients included in the study, 45 were male and ten were female, with a male to female ratio of 4.5:1. Their mean age was 39.5 (range 13–61) years. Bone loss indicated by low BMD revealed that the femoral region was predominantly affected, with relative preservation of the lumbar spine. Abnormal BMD values were detected in 83.6% of subjects, and fractures occurred in 16.4% following minor trauma. A positive correlation was noted between time since injury and degree of osteoporosis. Individuals with complete lesions showed lower BMD values than those with incomplete lesions. No significant correlation was found with age or sex.Conclusion: SCI patients are at high risk of developing osteoporosis, which can lead to significant morbidity, particularly lower extremity fractures without significant trauma. Prevention and early treatment of bone loss are important in this patient group to avoid further functional impairment.Keywords: osteoporosis, spinal cord injury, bone loss, bone mineral density, American Spinal Injury Association

Cell therapy has been shown to be a key clinical therapeutic option for central nervous system diseases or damage. Standardization of clinical cell therapy procedures is an important task for professional associations devoted to cell therapy. The Chinese Branch of the International Association of Neurorestoratology (IANR) completed the first set of guidelines governing the clinical application of neurorestoration in 2011. The IANR and the Chinese Association of Neurorestoratology (CANR) collaborated to propose the current version “Clinical Cell Therapy Guidelines for Neurorestoration (IANR/CANR 2017)”. The IANR council board members and CANR committee members approved this proposal on September 1, 2016, and recommend it to clinical practitioners of cellular therapy. These guidelines include items of cell type nomenclature, cell quality control, minimal suggested cell doses, patient-informed consent, indications for undergoing cell therapy, contraindications for undergoing cell therapy, documentation of procedure and therapy, safety evaluation, efficacy evaluation, policy of repeated treatments, do not charge patients for unproven therapies, basic principles of cell therapy, and publishing responsibility.

Objective: The effectiveness of audiological monitoring for detecting early hearing changes in patients receiving ototoxic medication could be limited by the lack of adequate audiological ototoxicity monitoring (OtoM) guidelines. This study aimed to evaluate existing OtoM guidelines using the AGREE II tool for guideline evaluation. Design: Guideline Review. Study Sample: Three audiological OtoM guidelines. Results: An online search identified three audiological OtoM guidelines published by the American Speech-Language and Hearing Association (ASHA), the American Academy of Audiology (AAA) and the Health Professionals Council of South Africa (HPCSA). Evaluation using the Appraisal of Guidelines for Research and Evaluation (AGREE) II tool found the HPCSA audiological OtoM guideline scored higher than the ASHA and AAA guidelines in five of the six tool domains. All guidelines received average domain ratings of less than 50% with each reviewer recommending all three guidelines for use following modification. Conclusion: The findings of this study could partly explain the poor uptake of audiological OtoM practices internationally, further investigation is needed to identify the specific factors limiting the implementation of audiological OtoM in clinical practice. [ABSTRACT FROM AUTHOR]