271 results on '"O'Brien, Karel"'
Search Results
2. Supporting parents as essential care partners in neonatal units during the SARS-CoV-2 pandemic.
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van Veenendaal, Nicole R, Deierl, Aniko, Bacchini, Fabiana, O'Brien, Karel, Franck, Linda S, and International Steering Committee for Family Integrated Care
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International Steering Committee for Family Integrated Care ,Humans ,Parents ,Infant ,Newborn ,Caregivers ,Pandemics ,COVID-19 ,SARS-CoV-2 ,family centred care ,family integrated care ,neonatal ,parent ,Pediatrics ,Paediatrics and Reproductive Medicine - Abstract
AimTo review the evidence on safety of maintaining family integrated care practices and the effects of restricting parental participation in neonatal care during the SARS-CoV-2 pandemic.MethodsMEDLINE, EMBASE, PsycINFO and CINAHL databases were searched from inception to the 14th of October 2020. Records were included if they reported scientific, empirical research (qualitative, quantitative or mixed methods) on the effects of restricting or promoting family integrated care practices for parents of hospitalised neonates during the SARS-CoV-2 pandemic. Two authors independently screened abstracts, appraised study quality and extracted study and outcome data.ResultsWe retrieved 803 publications and assessed 75 full-text articles. Seven studies were included, reporting data on 854 healthcare professionals, 442 parents, 364 neonates and 26 other family members, within 286 neonatal units globally. The pandemic response resulted in significant changes in neonatal unit policies and restricting parents' access and participation in neonatal care. Breastfeeding, parental bonding, participation in caregiving, parental mental health and staff stress were negatively impacted.ConclusionThis review highlights that SARS-CoV-2 pandemic-related hospital restrictions had adverse effects on care delivery and outcomes for neonates, families and staff. Recommendations for restoring essential family integrated care practices are discussed.
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- 2021
3. Neonatal and Early Childhood Outcomes of Twin and Singleton Infants Born Preterm
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Shah, Prakesh S., Beltempo, Marc, Kanungo, Jaideep, Wong, Jonathan, Stavel, Miroslav, Sherlock, Rebecca, Mehrem, Ayman Abou, Toye, Jennifer, Ting, Joseph, Fajardo, Carlos, Bodani, Jaya, Strueby, Lannae, Seshia, Mary, Louis, Deepak, Alvaro, Ruben, Mukerji, Amit, Da Silva, Orlando, Augustine, Sajit, Lee, Kyong-Soon, Ng, Eugene, Lemyre, Brigitte, Daboval, Thierry, Khurshid, Faiza, Bizgu, Victoria, Barrington, Keith, Lapointe, Anie, Ethier, Guillaume, Drolet, Christine, Piedboeuf, Bruno, Claveau, Martine, St-Hilaire, Marie, Bertelle, Valerie, Masse, Edith, Mehdizadeh-Hakak, Hamid, Makary, Hala, Ojah, Cecil, Hudson, Jo-Anna, Afifi, Jehier, Aslam, Ameer, Lee, Shoo K., Abenhaim, Haim, Andrews, James, Armson, Anthony, Audibert, Francois, Aziz, Khalid, Ballantyne, Marilyn, Barrett, Jon, Berard, Anick, Blais, Lucie, Bocking, Alan, Burrows, Jason, Butt, Kimberly, Canning, Roderick, Carson, George, Chaillet, Nils, Chandra, Sue, Church, Paige, Cieslak, Zenon, Coughlin, Kevin, Crane, Joan, Creighton, Dianne, Dahlgren, Leanne, Daspal, Sibasis, de Cabo, Cecilia, Deshpandey, Akhil, Dow, Kimberly, Dunn, Michael, Helou, Salhab el, El-Chaar, Darine, El-Naggar, Walid, Foster, Jonathan, Gagnon, Robert, Gratton, Rob, Han, Victor, Harrison, Adele, Hasan, Shabih, Helewa, Michael, Hicks, Matthew, Joseph, K.S., Kajetanowicz, Andrzej, Kalapesi, Zarin, Khairy, May, Lacaze-Masmonteil, Thierry, Lodha, Abhay, Luu, Thuy Mai, Ly, Linh, Majnemer, Annette, Marc, Isabelle, McDonald, Sarah D., McMillan, Doug, Melamed, Nir, Metcalfe, Amy, Moddemann, Diane, Monterrosa, Luis, Morais, Michelle, Mundle, William, Murphy, Lynn, Murphy, Kellie, Nuyt, Anne-Monique, Nwaesei, Chuks, O'Brien, Karel, Offringa, Martin, Ouellet, Annie, Pasquier, Jean-Charles, Pechlivanoglou, Petros, Pelausa, Ermelinda, Portales-Casamar, Elodie, Premji, Shahirose, Puligandla, Pramod, Pullenayegum, Eleanor, Reichert, Amber, Robson, Kate, Schneider, Carol, Shah, Vibhuti, Shivananda, Sandesh, Singhal, Nalini, Skarsgard, Erik, Skoll, Amanda, Smith, Graeme, Synnes, Anne, Thériault, Katherine, Tough, Suzanne, Ubhi, Jagdeep, Vincer, Michael, Whittle, Wendy, Whyte, Hilary, Wilson, Doug, Wood, Stephen, Ye, Philip, Yee, Wendy, Zwicker, Jill, Pillay, Thevanisha, Synnes’, Anne, Colby, Lindsay, Anson, Shelagh, Moodley, Anitha, Hendson, Leonora, Ricci, M. Florencia, McKnight, Sarah, Kelly, Edmond, Raghuram, Kamini, Thomas, Karen, Banihani, Rudaina, Nguyen, Kim-Anh, Mandel, Ruth, Morin, Alyssa, Bélanger, Sylvie, Weitzner, Omer, and Yang, Junmin
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- 2023
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4. Hospitalising preterm infants in single family rooms versus open bay units: A systematic review and meta-analysis of impact on parents.
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van Veenendaal, Nicole R, van Kempen, Anne AMW, Franck, Linda S, O'Brien, Karel, Limpens, Jacqueline, van der Lee, Johanna H, van Goudoever, Johannes B, and van der Schoor, Sophie RD
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AA ,at admission ,BA ,before-after study ,BDI ,Beck Depression Inventory ,CI ,confidence interval ,EPDS ,Edinburgh Postnatal Depression Scale ,FCC ,Family-Centred Care ,FCCS ,Family-Centred Care Survey ,MPAS ,Maternal Postnatal Attachment Scale ,Mo ,months ,NA ,not applicable ,NICU ,Neonatal Intensive Care Unit ,NR ,not reported ,NRPI ,non-randomised prospective intervention study ,NRRI ,non-randomised retrospective intervention study ,OBU ,Open Bay Unit ,PES ,Parent Expectations Scale ,PG ,Press Ganey NICU Survey ,PRISMA ,Preferred Reporting Items for Systematic Reviews and Meta-analysis ,PROSPERO ,International Prospective Register of Systematic Reviews ,PSI ,Parental Stress Index ,PSS-NICU ,Parental Stressor Scale – NICU ,RCT ,Randomised Controlled Trial ,ROBINS-I ,Risk of Bias in Non-randomised Studies of Interventions ,RoB ,Risk of Bias ,SD ,standard deviation ,SFR ,Single Family Room ,SMD ,standardised mean difference ,SPSQ ,Swedish Parental Stress Index ,STAI ,State-Trait Anxiety Inventory ,Wks ,weeks ,AA ,at admission ,BA ,before-after study ,BDI ,Beck Depression Inventory ,CI ,confidence interval ,EPDS ,Edinburgh Postnatal Depression Scale ,FCC ,Family-Centred Care ,FCCS ,Family-Centred Care Survey ,MPAS ,Maternal Postnatal Attachment Scale ,Mo ,months ,NA ,not applicable ,NICU ,Neonatal Intensive Care Unit ,NR ,not reported ,NRPI ,non-randomised prospective intervention study ,NRRI ,non-randomised retrospective intervention study ,OBU ,Open Bay Unit ,PES ,Parent Expectations Scale ,PG ,Press Ganey NICU Survey ,PRISMA ,Preferred Reporting Items for Systematic Reviews and Meta-analysis ,PROSPERO ,International Prospective Register of Systematic Reviews ,PSI ,Parental Stress Index ,PSS-NICU ,Parental Stressor Scale – NICU ,RCT ,Randomised Controlled Trial ,ROBINS-I ,Risk of Bias in Non-randomised Studies of Interventions ,RoB ,Risk of Bias ,SD ,standard deviation ,SFR ,Single Family Room ,SMD ,standardised mean difference ,SPSQ ,Swedish Parental Stress Index ,STAI ,State-Trait Anxiety Inventory ,Wks ,weeks - Abstract
BackgroundMany parents develop stress-related symptoms and depression when their preterm infant is hospitalised in the neonatal intensive care unit (NICU) after birth. We reviewed the evidence of parent well-being with preterm infants hospitalised in single family rooms (SFRs) or in open bay neonatal units (OBUs).MethodsFor this systematic review and meta-analysis, we searched MEDLINE, EMBASE, PsycINFO, Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, Clinicaltrials.gov, and International Clinical Trials Registry Platform (ICTRP) databases from inception through 22 November 2019 using controlled terms and text words related to prematurity and NICU-design. We included randomised and non-randomised studies comparing outcomes in parents with preterm infants admitted to SFRs or OBUs. Methodological quality was assessed using Cochrane Collaboration's Risk of Bias Tool for randomised controlled trials and the Risk of Bias Tool for Non-Randomised Studies of Interventions (ROBINS-I). Outcomes included: parental stress, satisfaction, participation (presence/involvement/skin-to-skin care), self-efficacy, parent-infant-bonding, depression, anxiety, post-traumatic stress, empowerment, and degree of family-centred care. Summary estimates were calculated using random effects models with standardised mean differences (SMDs). PROSPERO registration: CRD42016050643.FindingsWe identified 614 unique publications. Eleven study populations (1, 850 preterm infants, 1, 549 mothers and 379 fathers) were included. All but one study were at serious to critical risk of bias. SFRs were associated with higher levels of parental presence, involvement, and skin-to-skin care. Upon discharge, SFRs were associated with lower stress levels (n = 828 parents, SMD-0·30,95%CI -0·50;-0·09, p
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- 2020
5. Family integrated care: State of art and future perspectives
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Moreno‐Sanz, Bárbara, primary, Alferink, Milène Tirza, additional, O'Brien, Karel, additional, and Franck, Linda S., additional
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- 2024
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6. Facilitators and constraints to family integrated care in low‐resource settings informed the adaptation in Uganda.
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Kabajassi, Olive, Reiter, Anna, Tagoola, Abner, Kenya‐Mugisha, Nathan, O'Brien, Karel, Wiens, Matthew O., Feeley, Nancy, and Duby, Jessica
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RESOURCE-limited settings ,MEDICAL personnel ,TASK shifting ,NEONATAL intensive care units ,HIGH-income countries - Abstract
Aim: Family Integrated Care (FICare) was developed in high‐income countries and has not been tested in resource‐poor settings. We aimed to identify the facilitators and constraints that informed the adaptation of FICare to a neonatal hospital unit in Uganda. Methods: Maternal focus groups and healthcare provider interviews were conducted at Uganda's Jinja Regional Referral Hospital in 2020. Transcripts were analysed using inductive content analysis. An adaptation team developed Uganda FICare based on the identified facilitators and constraints. Results: Participants included 10 mothers (median age 28 years) and eight healthcare providers (seven female, median age 41 years). Reducing healthcare provider workload, improving neonatal outcomes and empowering mothers were identified as facilitators. Maternal stress, maternal difficulties in learning new skills and mistrust of mothers by healthcare providers were cited as constraints. Uganda FICare focused on task‐shifting important but neglected patient care tasks from healthcare providers to mothers. Healthcare providers learned how to respond to maternal concerns. Intervention material was adapted to prioritise images over text. Mothers familiar with FICare provided peer‐to‐peer support to other mothers. Conclusion: Uganda FICare shares the core values of FICare but was adapted to be feasible in low‐resource settings. [ABSTRACT FROM AUTHOR]
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- 2024
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7. Rates and Determinants of Mother’s Own Milk Feeding in Infants Born Very Preterm
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Abenhaim, Haim, Afifi, Jehier, Alvaro, Ruben, Andrews, James, Armson, Anthony, Audibert, Francois, Aziz, Khalid, Ballantyne, Marilyn, Barrett, Jon, Beltempo, Marc, Berard, Anick, Bertelle, Valerie, Blais, Lucie, Bocking, Alan, Bodani, Jaya, Burrows, Jason, Butt, Kimberly, Canning, Roderick, Carson, George, Chaillet, Nils, Chandra, Sue, Church, Paige, Cieslak, Zenon, Coughlin, Kevin, Crane, Joan, Creighton, Dianne, Da Silva, Orlando, Daboval, Thierry, Dahlgren, Leanne, Daspal, Sibasis, de Cabo, Cecilia, Deshpandey, Akhil, Dow, Kimberly, Drolet, Christine, Dunn, Michael, el Helou, Salhab, El-Chaar, Darine, El-Naggar, Walid, Fajardo, Carlos, Foster, Jonathan, Gagnon, Robert, Gratton, Rob, Han, Victor, Harrison, Adele, Hasan, Shabih, Helewa, Michael, Hicks, Matthew, Joseph, K.S., Kajetanowicz, Andrzej, Kalapesi, Zarin, Khairy, May, Lacaze-Masmonteil, Thierry, Lee, Kyong-Soon, Lemyre, Brigitte, Lodha, Abhay, Louis, Deepak, Mai Luu, Thuy, Ly, Linh, Majnemer, Annette, Makary, Hala, Marc, Isabelle, Masse, Edith, McDonald, Sarah D., McMillan, Doug, Melamed, Nir, Metcalfe, Amy, Moddemann, Diane, Monterrosa, Luis, Morais, Michelle, Mukerji, Amit, Mundle, William, Murphy, Lynn, Murphy, Kellie, Nuyt, Anne-Monique, Nwaesei, Chuks, O’Brien, Karel, Offringa, Martin, Ojah, Cecil, Ouellet, Annie, Pasquier, Jean-Charles, Pechlivanoglou, Petros, Pelausa, Ermelinda, Piedboeuf, Bruno, Portales-Casamar, Elodie, Premji, Shahirose, Puligandla, Pramod, Pullenayegum, Eleanor, Reichert, Amber, Schneider, Carol, Seshia, Mary, Shah, Prakesh S., Shah, Vibhuti, Sherlock, Rebecca, Shivananda, Sandesh, Singhal, Nalini, Skarsgard, Erik, Skoll, Amanda, Smith, Graeme, Synnes, Anne, Thériault, Katherine, Ting, Joseph, Tough, Suzanne, Toye, Jennifer, Ubhi, Jagdeep, Vincer, Michael, Whittle, Wendy, Whyte, Hilary, Wilson, Doug, Wood, Stephen, Ye, Philip, Yee, Wendy, Zwicker, Jill, Dharel, Dinesh, Wood, Christel, Bacchini, Fabiana, Ye, Xiang Y., and Alshaikh, Belal
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- 2021
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8. Costs of Neonatal Intensive Care for Canadian Infants with Preterm Birth
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Abenhaim, Haim, Afifi, Jehier, Alvaro, Ruben, Andrews, James, Armson, Anthony, Audibert, Francois, Aziz, Khalid, Ballantyne, Marilyn, Barrett, Jon, Berard, Anick, Bertelle, Valerie, Blais, Lucie, Bocking, Alan, Bodani, Jaya, Burrows, Jason, Butt, Kimberly, Canning, Roderick, Carson, George, Chaillet, Nils, Chandra, Sue, Church, Paige, Cieslak, Zenon, Crane, Joan, Creighton, Dianne, Da Silva, Orlando, Daboval, Thierry, Dahlgren, Leanne, Daspal, Sibasis, de Cabo, Cecilia, Deshpandey, Akhil, Dow, Kimberly, Drolet, Christine, Dunn, Michael, Salhab el Helou, El-Chaar, Darine, El-Naggar, Walid, Fajardo, Carlos, Gagnon, Robert, Gratton, Rob, Han, Victor, Harrison, Adele, Hasan, Shabih, Helewa, Michael, Hicks, Matthew, Joseph, K.S., Kajetanowicz, Andrzej, Kalapesi, Zarin, Khairy, May, Lacaze-Masmonteil, Thierry, Lee, Kyong-Soon, Lemyre, Brigitte, Lodha, Abhay, Mai Luu, Thuy, Ly, Linh, Majnemer, Annette, Makary, Hala, Marc, Isabelle, Masse, Edith, McDonald, Sarah D., McMillan, Doug, Melamed, Nir, Metcalfe, Amy, Moddemann, Diane, Monterrosa, Luis, Morais, Michelle, Mundle, William, Murphy, Lynn, Murphy, Kellie, Nuyt, Anne-Monique, Nwaesei, Chuks, O’Brien, Karel, Offringa, Martin, Ojah, Cecil, Ouellet, Annie, Pasquier, Jean-Charles, Pelausa, Ermelinda, Piedboeuf, Bruno, Portales-Casamar, Elodie, Puligandla, Pramod, Pullenayegum, Eleanor, Reichert, Amber, Robson, Kate, Schneider, Carol, Seshia, Mary, Shah, Prakesh S., Sherlock, Rebecca, Shivananda, Sandesh, Singhal, Nalini, Skarsgard, Erik, Skoll, Amanda, Smith, Graeme, Synnes, Anne, Thériault, Katherine, Ting, Joseph, Tough, Suzanne, Toye, Jennifer, Ubhi, Jagdeep, Vincer, Michael, Whittle, Wendy, Whyte, Hilary, Wilson, Doug, Wood, Stephen, Ye, Philip, Yee, Wendy, Zwicker, Jill, Jaideep Kanungo, Mehrem, Ayman Abou, Sankaran, Koravangattu, Adie, Mohammad, Khurshid, Faiza, Barrington, Keith, Lapoint, Anie, Ethier, Guillaume, Claveau, Martine, Emberley, Julie, Rios, Juan D., Beltempo, Marc, Louis, Deepak, Mukerji, Amit, Premji, Shahirose, Shah, Vibhuti, Lee, Shoo K., and Pechlivanoglou, Petros
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- 2021
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9. Skin-to-skin care (SSC) for term and preterm infants.
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Altit, Gabriel, Hamilton, Danica, and O'Brien, Karel
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INFECTION prevention ,BREASTFEEDING ,MEDICAL protocols ,PARENTS ,CARDIOPULMONARY system physiology ,HYPOTHERMIA ,MENTAL health ,INFANT mortality ,BODY temperature regulation ,NEURAL development ,POSTNATAL care ,BREAST milk ,HUMAN microbiota ,INFANT care ,REACTIVE oxygen species ,OXYGEN in the body ,HEART beat ,SURGICAL complications ,PAIN ,PSYCHOLOGICAL stress ,PARENT-infant relationships ,IMMUNITY ,NEURAL tube defects - Abstract
Skin-to-skin care (SSC) is an important part of parent and infant care during the neonatal period and into infancy. SSC should be initiated immediately after birth and practiced as a standard of care in all settings, as well as in the home. There is strong evidence that SSC has a positive effect on breastfeeding and human milk feeding in both term and preterm infants, as well as on mortality, cardiopulmonary stability, and thermoregulation. SSC reduces pain and infant stress, enhances parent–infant bonding, has neurodevelopmental benefits, and has positive effects on parental mental health. The safety and feasibility of providing SSC has been established in term and preterm infants, and SSC is recommended as best practice for all infants. The benefits of SSC outweigh the risks in most situations, and despite challenges, care providers should implement procedures and accommodations to ensure that SSC occurs as a safe and positive experience for the parent, family, infant, and health care team. This statement includes all families as defined and determined by themselves, and recognizes that health communication, language, and terminology must be individualized to meet specific family needs by the health care team. [ABSTRACT FROM AUTHOR]
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- 2024
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10. Les soins peau-à-peau chez les nourrissons à terme et prématurés.
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Altit, Gabriel, Hamilton, Danica, and O'Brien, Karel
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Les soins peau-à-peau (SPP) sont un aspect important des soins au parent et au nourrisson pendant la période néonatale et la première enfance. Ils doivent être entrepris immédiatement après la naissance et faire partie des soins standards dans tous les milieux, y compris à la maison. Selon de solides données probantes, les SPP ont un effet positif sur l'allaitement et l'alimentation par du lait humain, tant chez les nourrissons à terme que prématurés, de même que sur la mortalité, la stabilité cardiorespiratoire et la thermorégulation. Les SPP réduisent la douleur et le stress chez les nourrissons, accroissent l'attachement entre le parent et son nourrisson et ont des effets bénéfiques sur le neurodéveloppement de l'enfant ainsi que sur la santé mentale des parents. Le caractère sécuritaire et la faisabilité des SPP sont établis chez les nourrissons à terme et prématurés, et ces soins sont recommandés dans le cadre d'une pratique exemplaire auprès de tous les nourrissons. Les avantages des SPP sont supérieurs aux risques dans la plupart des situations, et malgré les défis qui y sont associés, les dispensateurs de soins devraient adopter des protocoles et prévoir des adaptations pour s'assurer que les SPP soient une expérience positive et sécuritaire pour le parent, la famille, le nourrisson et l'équipe soignante. Le présent document de principes s'adresse à toutes les familles, telles qu'elles se définissent et se déterminent elles-mêmes, et tiennent compte de l'importance de personnaliser la communication, le langage et la terminologie en matière de santé pour que l'équipe soignante réponde aux besoins particuliers de la famille. [ABSTRACT FROM AUTHOR]
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- 2024
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11. Family Integrated Care for Preterm Infants
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Franck, Linda S., Waddington, Chandra, and O’Brien, Karel
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- 2020
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12. Hospitalising preterm infants in single family rooms versus open bay units: A systematic review and meta-analysis of impact on parents
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van Veenendaal, Nicole R., van Kempen, Anne A.M.W., Franck, Linda S., O'Brien, Karel, Limpens, Jacqueline, van der Lee, Johanna H., van Goudoever, Johannes B., and van der Schoor, Sophie R.D.
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- 2020
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13. Neonatal and Early Childhood Outcomes of Twin and Singleton Infants Born Preterm
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Melamed, Nir, primary, Weitzner, Omer, additional, Church, Paige, additional, Banihani, Rudaina, additional, Barrett, Jon, additional, Yang, Junmin, additional, Wong, Jonathan, additional, Piedboeuf, Bruno, additional, Shah, Prakesh S., additional, Beltempo, Marc, additional, Kanungo, Jaideep, additional, Stavel, Miroslav, additional, Sherlock, Rebecca, additional, Mehrem, Ayman Abou, additional, Toye, Jennifer, additional, Ting, Joseph, additional, Fajardo, Carlos, additional, Bodani, Jaya, additional, Strueby, Lannae, additional, Seshia, Mary, additional, Louis, Deepak, additional, Alvaro, Ruben, additional, Mukerji, Amit, additional, Da Silva, Orlando, additional, Augustine, Sajit, additional, Lee, Kyong-Soon, additional, Ng, Eugene, additional, Lemyre, Brigitte, additional, Daboval, Thierry, additional, Khurshid, Faiza, additional, Bizgu, Victoria, additional, Barrington, Keith, additional, Lapointe, Anie, additional, Ethier, Guillaume, additional, Drolet, Christine, additional, Claveau, Martine, additional, St-Hilaire, Marie, additional, Bertelle, Valerie, additional, Masse, Edith, additional, Mehdizadeh-Hakak, Hamid, additional, Makary, Hala, additional, Ojah, Cecil, additional, Hudson, Jo-Anna, additional, Afifi, Jehier, additional, Aslam, Ameer, additional, Lee, Shoo K., additional, Abenhaim, Haim, additional, Andrews, James, additional, Armson, Anthony, additional, Audibert, Francois, additional, Aziz, Khalid, additional, Ballantyne, Marilyn, additional, Berard, Anick, additional, Blais, Lucie, additional, Bocking, Alan, additional, Burrows, Jason, additional, Butt, Kimberly, additional, Canning, Roderick, additional, Carson, George, additional, Chaillet, Nils, additional, Chandra, Sue, additional, Cieslak, Zenon, additional, Coughlin, Kevin, additional, Crane, Joan, additional, Creighton, Dianne, additional, Dahlgren, Leanne, additional, Daspal, Sibasis, additional, de Cabo, Cecilia, additional, Deshpandey, Akhil, additional, Dow, Kimberly, additional, Dunn, Michael, additional, Helou, Salhab el, additional, El-Chaar, Darine, additional, El-Naggar, Walid, additional, Foster, Jonathan, additional, Gagnon, Robert, additional, Gratton, Rob, additional, Han, Victor, additional, Harrison, Adele, additional, Hasan, Shabih, additional, Helewa, Michael, additional, Hicks, Matthew, additional, Joseph, K.S., additional, Kajetanowicz, Andrzej, additional, Kalapesi, Zarin, additional, Khairy, May, additional, Lacaze-Masmonteil, Thierry, additional, Lodha, Abhay, additional, Luu, Thuy Mai, additional, Ly, Linh, additional, Majnemer, Annette, additional, Marc, Isabelle, additional, McDonald, Sarah D., additional, McMillan, Doug, additional, Melamed, Nir, additional, Metcalfe, Amy, additional, Moddemann, Diane, additional, Monterrosa, Luis, additional, Morais, Michelle, additional, Mundle, William, additional, Murphy, Lynn, additional, Murphy, Kellie, additional, Nuyt, Anne-Monique, additional, Nwaesei, Chuks, additional, O'Brien, Karel, additional, Offringa, Martin, additional, Ouellet, Annie, additional, Pasquier, Jean-Charles, additional, Pechlivanoglou, Petros, additional, Pelausa, Ermelinda, additional, Portales-Casamar, Elodie, additional, Premji, Shahirose, additional, Puligandla, Pramod, additional, Pullenayegum, Eleanor, additional, Reichert, Amber, additional, Robson, Kate, additional, Schneider, Carol, additional, Shah, Vibhuti, additional, Shivananda, Sandesh, additional, Singhal, Nalini, additional, Skarsgard, Erik, additional, Skoll, Amanda, additional, Smith, Graeme, additional, Synnes, Anne, additional, Thériault, Katherine, additional, Tough, Suzanne, additional, Ubhi, Jagdeep, additional, Vincer, Michael, additional, Whittle, Wendy, additional, Whyte, Hilary, additional, Wilson, Doug, additional, Wood, Stephen, additional, Ye, Philip, additional, Yee, Wendy, additional, Zwicker, Jill, additional, Pillay, Thevanisha, additional, Synnes’, Anne, additional, Colby, Lindsay, additional, Anson, Shelagh, additional, Moodley, Anitha, additional, Hendson, Leonora, additional, Ricci, M. Florencia, additional, McKnight, Sarah, additional, Kelly, Edmond, additional, Raghuram, Kamini, additional, Thomas, Karen, additional, Nguyen, Kim-Anh, additional, Mandel, Ruth, additional, Morin, Alyssa, additional, and Bélanger, Sylvie, additional
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- 2023
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14. A Pilot Study of Family-Integrated Care (FICare) in Critically Ill Preterm and Term Infants in the NICU: FICare Plus
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Ansari, Najmus Sehr, primary, Franck, Linda S., additional, Tomlinson, Christopher, additional, Colucci, Anna, additional, and O’Brien, Karel, additional
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- 2023
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15. Building Connections with Families: Implementation of a Video-Messaging Service in the Neonatal Intensive Care Unit
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Bott, Stephanie, primary, Dantas Fernandez, Nicole, additional, Narciso, Janet, additional, MacAlpine, Janet, additional, Quain, Nicole, additional, Rettie, Julia, additional, Sharpe, Lia, additional, Diambomba, Yenge, additional, Al Bizri, Ayah, additional, O’Brien, Karel, additional, and Shah, Vibhuti, additional
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- 2023
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16. Early-Onset Invasive Candidiasis in Extremely Low Birth Weight Infants: Perinatal Acquisition Predicts Poor Outcome
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Paediatric Investigators Collaborative Network on Infections in Canada (PICNIC), Barton, Michelle, Shen, Alex, O'Brien, Karel, Robinson, Joan L., Davies, H. Dele, Simpson, Kim, Asztalos, Elizabeth, Langley, Joanne, Le Saux, Nicole, Sauve, Reginald, Synnes, Anne, Tan, Ben, de Repentigny, Louis, Rubin, Earl, Hui, Chuck, Kovacs, Lajos, Yau, Yvonne C. W., and Richardson, Susan E.
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- 2017
17. Understanding the Family Context: A Qualitative Descriptive Study of Parent and NICU Clinician Experiences and Perspectives
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Dahan, Maya, primary, Rotteau, Leahora, additional, Higazi, Shelley, additional, Kwayke, Ophelia, additional, Lai, Giselle, additional, Moulsdale, Wendy, additional, Sampson, Lisa, additional, Stannard, Jennifer, additional, Church, Paige Terrien, additional, and O’Brien, Karel, additional
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- 2023
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18. Evaluating the facilitators and constraints that informed the adaptation of Family Integrated Care to a Ugandan neonatal hospital unit: a qualitative study
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Kabajassi, Olive, primary, Reiter, Anna, additional, Tagoola, Abner, additional, Kenya-Mugisha, Nathan, additional, O’Brien, Karel, additional, Wiens, Matthew O., additional, Feeley, Nancy, additional, and Duby, Jessica, additional
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- 2023
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19. Healthcare professionals' perceptions of pain in infants at risk for neurological impairment
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Breau, Lynn M, McGrath, Patrick J, Stevens, Bonnie, Beyene, Joseph, Camfield, Carol S, Finley, G Allen, Franck, Linda, Howlett, Alexandra, O'Brien, Karel, and Ohlsson, Arne
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Chronic Pain ,Infant Mortality ,Clinical Research ,Pediatric ,Perinatal Period - Conditions Originating in Perinatal Period ,Neurosciences ,Pain Research ,Neurological ,Adult ,Analysis of Variance ,Attitude of Health Personnel ,Canada ,Empathy ,Female ,Health Knowledge ,Attitudes ,Practice ,Humans ,Infant Care ,Infant ,Newborn ,Intensive Care Units ,Neonatal ,Judgment ,Male ,Middle Aged ,Nervous System Diseases ,Pain ,Pain Measurement ,Personnel ,Hospital ,Risk Assessment ,Workforce ,Paediatrics and Reproductive Medicine ,Pediatrics - Abstract
BackgroundTo determine whether healthcare professionals perceive the pain of infants differently due to their understanding of that infant's level of risk for neurological impairment.MethodNeonatal Intensive Care Units (NICU's) at two tertiary pediatric centers. Ninety-five healthcare professionals who practice in the NICU (50 nurses, 19 physicians, 17 respiratory therapists, 9 other) participated. They rated the pain (0-10 scale and 0-6 Faces Pain Scale), distress (0-10), effectiveness of cuddling to relieve pain (0-10) and time to calm without intervention (seconds) for nine video clips of neonates receiving a heel stick. Prior to each rating, they were provided with descriptions that suggested the infant had mild, moderate or severe risk for neurological impairment. Ratings were examined as a function of the level of risk described.ResultsProfessionals' ratings of pain, distress, and time to calm did not vary significantly with level of risk, but ratings of the effectiveness of cuddling were significantly lower as risk increased [F (2,93) = 4.4, p = .02]. No differences in ratings were found due to participants' age, gender or site of study. Physicians' ratings were significantly lower than nurses' across ratings.ConclusionProfessionals provided with visual information regarding an infants' pain during a procedure did not display the belief that infants' level of risk for neurological impairment affected their pain experience. Professionals' estimates of the effectiveness of a nonpharmacological intervention did differ due to level of risk.
- Published
- 2004
20. Parents Are Not Visiting. Parents Are Parenting
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Bracht, Marianne, primary, Franck, Linda S., additional, O'Brien, Karel, additional, and Bacchini, Fabiana, additional
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- 2023
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21. Prediction of Late Death or Disability at Age 5 Years Using a Count of 3 Neonatal Morbidities in Very Low Birth Weight Infants
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Schmidt, Barbara, D'Ilario, Judy, Cairnie, Janice, Dix, Joanne, Adams, Beth Anne, Warriner, Erin, Marie Kim, Mee-Hai, Anderson, Peter, Davis, Peter, Doyle, Lex, Argus, Brenda, Callanan, Catherine, Davis, Noni, Duff, Julianne, McDonald, Marion, Asztalos, Elizabeth, Hohn, Denise, Lacy, Maralyn, Haslam, Ross, Barnett, Christopher, Goodchild, Louise, Lontis, Rosslyn Marie, Fraser, Simon, Keng, Julie, Saunders, Kerryn, Opie, Gillian, Kelly, Elaine, Woods, Heather, Marchant, Emma, Turner, Anne-Marie, Magrath, Emma, Williamson, Amanda, Bairam, Aida, Bélanger, Sylvie, Fraser, Annie, Blayney, Marc, Lemyre, Brigitte, Frank, Jane, Solimano, Alfonso, Synnes, Anne, Grunau, Ruth E., Hubber-Richard, Philippa, Rogers, Marilyn, Mackay, Margot, Petrie-Thomas, Julianne, Butt, Arsalan, van Wassenaer, Aleid, Nuytemans, Debbie, Houtzager, Bregje, van Sonderen, Loekie, Regev, Rivka, Itzchack, Netter, Arnon, Shmuel, Chalaf, Adiba, Ohlsson, Arne, O'Brien, Karel, Hamilton, Anne-Marie, Chan, May Lee, Sankaran, Koravangattu, Proctor, Pat, Golan, Agneta, Goldsch-Lerman, Esther, Reynolds, Graham, Dromgool, Barbara, Meskell, Sandra, Parr, Vanessa, Maher, Catherine, Broom, Margaret, Kecskes, Zsuzsoka, Ringland, Cathy, McMillan, Douglas, Spellen, Elizabeth, Sauve, Reginald S., Christianson, Heather, Anseeuw-Deeks, Deborah, Creighton, Dianne, Heath, Jennifer, Alvaro, Ruben, Chiu, Aaron, Porter, Ceceile, Turner, Gloria, Moddemann, Diane, Granke, Naomi, Penner, Karen, Bow, Jane, Mulder, Antonius, Wassenberg, Renske, van der Hoeven, Markus, Clarke, Maxine, Parfitt, Judy, Parker, Kevin, Nwaesei, Chukwuma, Ryan, Heather, Saunders, Cory, Schulze, Andreas, Wermuth, Inga, Hilgendorff, Anne, Flemmer, Andreas W., Herlenius, Eric, Legnevall, Lena, Lagercrantz, Hugo, Matthew, Derek, Amos, Wendy, Tulsiani, Suresh, Tan-Dy, Cherrie, Turner, Marilyn, Phelan, Constance, Shinwell, Eric S., Levine, Michael, Juster-Reicher, Ada, Khairy, May, Grier, Patricia, Vachon, Julie, Perepolkin, Larissa, Barrington, Keith J., Sinha, Sunil Kumar, Tin, Win, Fritz, Susan, Walti, Herve, Royer, Diane, Halliday, Henry, Millar, David, Mayes, Clifford, McCusker, Christopher, McLaughlin, Olivia, Fahnenstich, Hubert, Tillmann, Bettina, Weber, Peter, Wariyar, Unni, Embleton, Nicholas, Swamy, Ravi, Bucher, Hans U., Fauchere, Jean-Claude, Dietz, Vera, Harikumar, Chidambara, Anderson, Peter J., Asztalos, Elizabeth V., Davis, Peter G., Dewey, Deborah, Doyle, Lex W., Roberts, Robin S., Gent, Michael, Fraser, William, Hey, Edmund, Perlman, Max, Thorpe, Kevin, Gray, Shari, Chambers, Carole, Costantini, Lorrie, Yacura, Wendy, McGean, Erin, and Scapinello, Lori
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- 2015
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22. Social Variables Predict Gains in Cognitive Scores across the Preschool Years in Children with Birth Weights 500 to 1250 Grams
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Schmidt, Barbara, D'Ilario, Judy, Cairnie, Janice, Dix, Joanne, Anne Adams, Beth, Warriner, Erin, Kim, Mee-Hai Marie, Anderson, Peter, Davis, Peter, Doyle, Lex, Argus, Brenda, Callanan, Catherine, Davis, Noni, Duff, Julianne, McDonald, Marion, Asztalos, Elizabeth, Hohn, Denise, Lacy, Maralyn, Haslam, Ross, Barnett, Christopher, Goodchild, Louise, Lontis, Rosslyn Marie, Fraser, Simon, Keng, Julie, Saunders, Kerryn, Opie, Gillian, Kelly, Elaine, Woods, Heather, Marchant, Emma, Turner, Anne-Marie, Magrath, Emma, Williamson, Amanda, Bairam, Aida, Bélanger, Sylvie, Fraser, Annie, Blayney, Marc, Lemyre, Brigitte, Frank, Jane, Solimano, Alfonso, Synnes, Anne, Grunau, Ruth E., Hubber-Richard, Philippa, Rogers, Marilyn, Mackay, Margot, Petrie-Thomas, Julianne, Butt, Arsalan, van Wassenaer, Aleid, Nuytemans, Debbie, Houtzager, Bregje, van Sonderen, Loekie, Regev, Rivka, Itzchack, Netter, Arnon, Shmuel, Chalaf, Adiba, Ohlsson, Arne, O'Brien, Karel, Hamilton, Anne-Marie, Chan, May Lee, Sankaran, Koravangattu, Proctor, Pat, Golan, Agneta, Goldsch-Lerman, Esther, Reynolds, Graham, Dromgool, Barbara, Meskell, Sandra, Parr, Vanessa, Maher, Catherine, Broom, Margaret, Kecskes, Zsuzsoka, Ringland, Cathy, McMillan, Douglas, Spellen, Elizabeth, Sauve, Reginald S., Christianson, Heather, Anseeuw-Deeks, Deborah, Creighton, Dianne, Heath, Jennifer, Alvaro, Ruben, Chiu, Aaron, Porter, Ceceile, Turner, Gloria, Moddemann, Diane, Granke, Naomi, Penner, Karen, Bow, Jane, Mulder, Antonius, Wassenberg, Renske, van der Hoeven, Markus, Clarke, Maxine, Parfitt, Judy, Parker, Kevin, Nwaesei, Chukwuma, Ryan, Heather, Saunders, Cory, Schulze, Andreas, Wermuth, Inga, Hilgendorff, Anne, Flemmer, Andreas W., Herlenius, Eric, Legnevall, Lena, Lagercrantz, Hugo, Matthew, Derek, Amos, Wendy, Tulsiani, Suresh, Tan-Dy, Cherrie, Turner, Marilyn, Phelan, Constance, Shinwell, Eric S., Levine, Michael, Juster-Reicher, Ada, Khairy, May, Grier, Patricia, Vachon, Julie, Perepolkin, Larissa, Barrington, Keith J., Sinha, Sunil Kumar, Tin, Win, Fritz, Susan, Walti, Herve, Royer, Diane, Halliday, Henry, Millar, David, Mayes, Clifford, McCusker, Christopher, McLaughlin, Olivia, Fahnenstich, Hubert, Tillmann, Bettina, Weber, Peter, Wariyar, Unni, Embleton, Nicholas, Swamy, Ravi, Bucher, Hans U., Fauchere, Jean-Claude., Dietz, Vera, Harikumar, Chidambara, Anderson, Peter J., Asztalos, Elizabeth V., Davis, Peter G., Dewey, Deborah, Doyle, Lex W., Roberts, Robin S., Gent, Michael, Fraser, William, Hey, Edmund, Perlman, Max, Thorpe, Kevin, Gray, Shari, Chambers, Carole, Costantini, Lorrie, Yacura, Wendy, McGean, Erin, Scapinello, Lori, Manley, Brett J., Böhm, Birgitta, and van Wassenaer-Leemhuis, Aleid G.
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- 2015
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23. Family Integrated Care in Uganda: a feasibility study
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Duby, Jessica, primary, Kabajaasi, Olive, additional, Muteteri, Judith, additional, Kisooka, Efulansi, additional, Barth, Delaney, additional, Feeley, Nancy, additional, O'Brien, Karel, additional, Nathan, Kenya-Mugisha, additional, Tagoola, Abner, additional, and Wiens, Matthew O, additional
- Published
- 2022
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24. 85 Mental health service utilization and cost amongst parents post NICU discharge: A descriptive analysis
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Diamond, Laura, primary, Moretti, Myla E, additional, Esser, Kayla, additional, Cohen, Eyal, additional, O'Brien, Karel, additional, Ungar, Wendy J, additional, and Orkin, Julia, additional
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- 2022
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25. Family Integrated Care in Uganda: a feasibility study.
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Duby, Jessica, Kabajaasi, Olive, Muteteri, Judith, Kisooka, Efulansi, Barth, Delaney, Feeley, Nancy, O'Brien, Karel, Nathan, Kenya-Mugisha, Tagoola, Abner, and Wiens, Matthew O.
- Subjects
NEONATAL nursing ,NEONATAL mortality ,MECONIUM aspiration syndrome ,FAMILY support ,HOSPITAL care quality - Abstract
Objective: To determine the feasibility of adapting Family Integrated Care to a neonatal hospital unit in a low-income country.Design: Single-centre, pre/post-pilot study of an adapted Family Integrated Care programme in Uganda (UFICare).Setting: Special Care Nursery at a Ugandan hospital.Patients: Singleton, inborn neonates with birth weight ≥2 kg.Interventions: As part of UFICare, mothers weighed their infant daily, assessed for severe illness ('danger signs') twice daily and tracked feeds.Main Outcome Measures: Feasibility outcomes included maternal proficiency and completion of monitoring tasks. Secondary outcomes included maternal stress, discharge readiness and post-discharge healthcare seeking.Results: Fifty-three mother-infant dyads and 51 mother-infant dyads were included in the baseline and intervention groups, respectively. Most mothers were proficient in the tasks 2-4 days after training (weigh 43 of 51; assess danger signs 49 of 51; track feeds 49 of 51). Mothers documented their danger sign assessments 82% (IQR 71-100) of the expected times and documented feeds 83% (IQR 71-100) of hospital days. In the baseline group, nurses weighed babies 29% (IQR 18-50) of hospitalised days, while UFICare mothers weighed their babies 71% (IQR 57-80) of hospitalised days (p<0.001). UFICare mothers had higher Readiness for Discharge scores compared with the baseline group (baseline 6.8; UFICare 7.9; p<0.001). There was no difference in maternal stress scores or post-discharge healthcare seeking.Conclusions: Ugandan mothers can collaborate in the medical care of their hospitalised infant. By performing tasks identified as important for infant care, mothers felt more prepared to care for their infant at discharge. [ABSTRACT FROM AUTHOR]- Published
- 2023
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26. Lower Maternal Chronic Physiological Stress and Better Child Behavior at 18 Months: Follow-Up of a Cluster Randomized Trial of Neonatal Intensive Care Unit Family Integrated Care
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Mclean, Mia A., primary, Scoten, Olivia C., additional, Yu, Wayne, additional, Ye, Xiang Y., additional, Petrie, Julie, additional, Church, Paige T., additional, Soraisham, Amuchou S., additional, Mirea, Lucia S., additional, Weinberg, Joanne, additional, Synnes, Anne R., additional, O'Brien, Karel, additional, and Grunau, Ruth E., additional
- Published
- 2022
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27. Motivated by Money? The Impact of Financial Incentive for the Research Team on Study Recruitment
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Unger, Sharon, Wylie, Lesley, Fallah, Shafagh, Heinrich, Lee, and O'Brien, Karel
- Published
- 2010
28. Influence of risk of neurological impairment and procedure invasiveness on health professionals’ management of procedural pain in neonates
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Stevens, Bonnie, McGrath, Patrick, Ballantyne, Marilyn, Yamada, Janet, Dupuis, Annie, Gibbins, Sharyn, Franck, Linda, Allen Finley, G., Howlett, Alexandra, Johnston, Celeste, O’Brien, Karel, and Ohlsson, Arne
- Published
- 2010
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29. Family Integrated Care reduces NICU length of stay and improves medical outcomes across China
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O'Brien, Karel K.
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- 2021
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30. Rates and Determinants of Mother’s Own Milk Feeding in Infants Born Very Preterm
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Dharel, Dinesh, primary, Singhal, Nalini, additional, Wood, Christel, additional, Cieslak, Zenon, additional, Bacchini, Fabiana, additional, Shah, Prakesh S., additional, Ye, Xiang Y., additional, Alshaikh, Belal, additional, Abenhaim, Haim, additional, Afifi, Jehier, additional, Alvaro, Ruben, additional, Andrews, James, additional, Armson, Anthony, additional, Audibert, Francois, additional, Aziz, Khalid, additional, Ballantyne, Marilyn, additional, Barrett, Jon, additional, Beltempo, Marc, additional, Berard, Anick, additional, Bertelle, Valerie, additional, Blais, Lucie, additional, Bocking, Alan, additional, Bodani, Jaya, additional, Burrows, Jason, additional, Butt, Kimberly, additional, Canning, Roderick, additional, Carson, George, additional, Chaillet, Nils, additional, Chandra, Sue, additional, Church, Paige, additional, Coughlin, Kevin, additional, Crane, Joan, additional, Creighton, Dianne, additional, Da Silva, Orlando, additional, Daboval, Thierry, additional, Dahlgren, Leanne, additional, Daspal, Sibasis, additional, de Cabo, Cecilia, additional, Deshpandey, Akhil, additional, Dow, Kimberly, additional, Drolet, Christine, additional, Dunn, Michael, additional, el Helou, Salhab, additional, El-Chaar, Darine, additional, El-Naggar, Walid, additional, Fajardo, Carlos, additional, Foster, Jonathan, additional, Gagnon, Robert, additional, Gratton, Rob, additional, Han, Victor, additional, Harrison, Adele, additional, Hasan, Shabih, additional, Helewa, Michael, additional, Hicks, Matthew, additional, Joseph, K.S., additional, Kajetanowicz, Andrzej, additional, Kalapesi, Zarin, additional, Khairy, May, additional, Lacaze-Masmonteil, Thierry, additional, Lee, Kyong-Soon, additional, Lemyre, Brigitte, additional, Lodha, Abhay, additional, Louis, Deepak, additional, Mai Luu, Thuy, additional, Ly, Linh, additional, Majnemer, Annette, additional, Makary, Hala, additional, Marc, Isabelle, additional, Masse, Edith, additional, McDonald, Sarah D., additional, McMillan, Doug, additional, Melamed, Nir, additional, Metcalfe, Amy, additional, Moddemann, Diane, additional, Monterrosa, Luis, additional, Morais, Michelle, additional, Mukerji, Amit, additional, Mundle, William, additional, Murphy, Lynn, additional, Murphy, Kellie, additional, Nuyt, Anne-Monique, additional, Nwaesei, Chuks, additional, O’Brien, Karel, additional, Offringa, Martin, additional, Ojah, Cecil, additional, Ouellet, Annie, additional, Pasquier, Jean-Charles, additional, Pechlivanoglou, Petros, additional, Pelausa, Ermelinda, additional, Piedboeuf, Bruno, additional, Portales-Casamar, Elodie, additional, Premji, Shahirose, additional, Puligandla, Pramod, additional, Pullenayegum, Eleanor, additional, Reichert, Amber, additional, Schneider, Carol, additional, Seshia, Mary, additional, Shah, Vibhuti, additional, Sherlock, Rebecca, additional, Shivananda, Sandesh, additional, Skarsgard, Erik, additional, Skoll, Amanda, additional, Smith, Graeme, additional, Synnes, Anne, additional, Thériault, Katherine, additional, Ting, Joseph, additional, Tough, Suzanne, additional, Toye, Jennifer, additional, Ubhi, Jagdeep, additional, Vincer, Michael, additional, Whittle, Wendy, additional, Whyte, Hilary, additional, Wilson, Doug, additional, Wood, Stephen, additional, Ye, Philip, additional, Yee, Wendy, additional, and Zwicker, Jill, additional
- Published
- 2021
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31. Gravens by Design: Family Integrated Care: An Evidence-Based and Inclusive Model for Delivering on Your NICU's Commitment to Family-Centered Care.
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Franck, Linda S. and O'Brien, Karel
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- *
EVALUATION of medical care , *NEONATAL intensive care , *PATIENT participation , *EVIDENCE-based medicine , *CONFERENCES & conventions , *FAMILY-centered care , *COMPASSION , *HUMAN services programs , *PSYCHOLOGY of caregivers , *INTERPERSONAL relations , *COMMITMENT (Psychology) - Abstract
The article focuses on promoting family-centered care in neonatal intensive care units (NICUs) and the implementation of the Family Integrated Care (FICare) model. It emphasizes that safe and high-quality neonatal care is best provided when the parents or primary caregivers are actively involved. It also highlights the negative consequences for infants, parents, healthcare professionals, and healthcare delivery systems when family- and community-centered neonatal care is not provided.
- Published
- 2023
32. Coached, Coordinated, Enhanced Neonatal Transition (CCENT): protocol for a multicentre pragmatic randomised controlled trial of transition-to-home support for parents of high-risk infants
- Author
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Orkin, Julia, primary, Major, Nathalie, additional, Esser, Kayla, additional, Parmar, Arpita, additional, Couture, Elise, additional, Daboval, Thierry, additional, Kieran, Emily, additional, Ly, Linh, additional, O'Brien, Karel, additional, Patel, Hema, additional, Synnes, Anne, additional, Robson, Kate, additional, Barreira, Lesley, additional, Smith, Wanda L, additional, Rizakos, Sara, additional, Willan, Andrew R, additional, Yaskina, Maryna, additional, Moretti, Myla E, additional, Ungar, Wendy J, additional, Ballantyne, Marilyn, additional, Church, Paige Terrien, additional, and Cohen, Eyal, additional
- Published
- 2021
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33. Mode of delivery and neonatal outcomes in extremely preterm Vertex/nonVertex twins
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Hiersch, Liran, primary, Shah, Prakesh S., additional, Khurshid, Faiza, additional, Masse, Edith, additional, Murphy, Kellie, additional, McDonald, Sarah D., additional, Carson, George, additional, Barrett, Jon, additional, Melamed, Nir, additional, Ting, Joseph, additional, Cieslak, Zenon, additional, Sherlock, Rebecca, additional, Abou Mehrem, Ayman, additional, Toye, Jennifer, additional, Fajardo, Carlos, additional, Kalapesi, Zarin, additional, Bodani, Jaya, additional, Sankaran, Koravangattu, additional, Daspal, Sibasis, additional, Seshia, Mary, additional, Louis, Deepak, additional, Alvaro, Ruben, additional, Mukerji, Amit, additional, Da Silva, Orlando, additional, Adie, Mohammad, additional, Lee, Kyong-Soon, additional, Dunn, Michael, additional, Lemyre, Brigitte, additional, Pelausa, Ermelinda, additional, Barrington, Keith, additional, Lapoint, Anie, additional, Ethier, Guillaume, additional, Drolet, Christine, additional, Piedboeuf, Bruno, additional, Claveau, Martine, additional, Beltempo, Marc, additional, Bertelle, Valerie, additional, Canning, Roderick, additional, Makary, Hala, additional, Ojah, Cecil, additional, Monterrosa, Luis, additional, Emberley, Julie, additional, Afifi, Jehier, additional, Kajetanowicz, Andrzej, additional, Lee, Shoo K., additional, Abenhaim, Haim, additional, Andrews, James, additional, Armson, Anthony, additional, Audibert, Francois, additional, Aziz, Khalid, additional, Ballantyne, Marilyn, additional, Berard, Anick, additional, Blais, Lucie, additional, Bocking, Alan, additional, Burrows, Jason, additional, Butt, Kimberly, additional, Chaillet, Nils, additional, Chandra, Sue, additional, Church, Paige, additional, Coughlin, Kevin, additional, Crane, Joan, additional, Creighton, Dianne, additional, Daboval, Thierry, additional, Dahlgren, Leanne, additional, de Cabo, Cecilia, additional, Deshpandey, Akhil, additional, Dow, Kimberly, additional, el Helou, Salhab, additional, El-Chaar, Darine, additional, El-Naggar, Walid, additional, Foster, Jonathan, additional, Gagnon, Robert, additional, Gratton, Rob, additional, Han, Victor, additional, Harrison, Adele, additional, Hasan, Shabih, additional, Helewa, Michael, additional, Hicks, Matthew, additional, Joseph, K.S., additional, Lacaze-Masmonteil, Thierry, additional, Lodha, Abhay, additional, Luu, Thuy Mai, additional, Ly, Linh, additional, Majnemer, Annette, additional, Marc, Isabelle, additional, McMillan, Doug, additional, Metcalfe, Amy, additional, Moddemann, Diane, additional, Morais, Michelle, additional, Mundle, William, additional, Murphy, Lynn, additional, Nuyt, Anne-Monique, additional, Nwaesei, Chuks, additional, O’Brien, Karel, additional, Offringa, Martin, additional, Ouellet, Annie, additional, Pasquier, Jean-Charles, additional, Pechlivanoglou, Petros, additional, Portales-Casamar, Elodie, additional, Premji, Shahirose, additional, Puligandla, Pramod, additional, Pullenayegum, Eleanor, additional, Reichert, Amber, additional, Robson, Kate, additional, Schneider, Carol, additional, Shah, Vibhuti, additional, Shivananda, Sandesh, additional, Singhal, Nalini, additional, Skarsgard, Erik, additional, Skoll, Amanda, additional, Smith, Graeme, additional, Synnes, Anne, additional, Thériault, Katherine, additional, Tough, Suzanne, additional, Ubhi, Jagdeep, additional, Vincer, Michael, additional, Whittle, Wendy, additional, Whyte, Hilary, additional, Wilson, Doug, additional, Wood, Stephen, additional, Ye, Philip, additional, Yee, Wendy, additional, and Zwicker, Jill, additional
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- 2021
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34. Parents as primary caregivers in the neonatal intensive care unit
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Lee, Shoo K. and O’Brien, Karel
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- 2014
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35. Development and validation of a risk scoring tool to predict respiratory syncytial virus hospitalization in premature infants born at 33 through 35 completed weeks of gestation
- Author
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Sampalis, John S., Langley, Joanne, Carbonell-Estrany, Xavier, Paes, Bosco, O'Brien, Karel, Allen, Upton, Mitchell, Ian, Figueras Aloy, Jose, Pedraz, Carmen, and Michaliszyn, Andrea F.
- Subjects
Health risk assessment -- Management -- Research -- Health aspects ,Infants (Premature) -- Research -- Health aspects ,Respiratory syncytial virus -- Diagnosis -- Research -- Risk factors -- Health aspects ,Health ,Company business management ,Management ,Diagnosis ,Research ,Risk factors ,Health aspects - Abstract
Keywords: hospitalization; prematurity; respiratory syncytial virus; risk assessment; risk factors; scoring tool. 471 Risk Factor AssessmentDevelopment and Validation of a Risk Scoring Tool to Predict Respiratory Syncytial Virus Hospitalization in [...]
- Published
- 2008
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36. Determining behavioural and physiological responses to pain in infants at risk for neurological impairment
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Stevens, Bonnie, McGrath, Patrick, Gibbins, Sharyn, Beyene, Joseph, Breau, Lynn, Camfield, Carol, Finley, Allen, Franck, Linda, Howlett, Alexandra, Johnston, Celeste, McKeever, Patricia, O’Brien, Karel, Ohlsson, Arne, and Yamada, Janet
- Published
- 2007
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37. Family Integrated Care (FICare): Positive impact on behavioural outcomes at 18 months
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Church, Paige Terrien, primary, Grunau, Ruth E., additional, Mirea, Lucia, additional, Petrie, Julie, additional, Soraisham, Amuchou Singh, additional, Synnes, Anne, additional, Ye, Xiang Y., additional, and O'Brien, Karel, additional
- Published
- 2020
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38. Complications Associated With Surgically Placed Central Venous Catheters In Low Birth Weight Neonates
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Pandit, Paresh B, Pandit, Florence A, Govan, Jairaj, and O’Brien, Karel
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- 1999
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39. A Neonate with Blisters
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Erdle, Stephanie C., primary and O’Brien, Karel, additional
- Published
- 2020
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40. A multilayered approach is needed in the NICU to support parents after the preterm birth of their infant
- Author
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Treyvaud, Karli, primary, Spittle, Alicia, additional, Anderson, Peter J., additional, and O'Brien, Karel, additional
- Published
- 2019
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41. Indicators of pain in neonates at risk for neurological impairment
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Stevens, Bonnie, McGrath, Patrick, Dupuis, Annie, Gibbins, Sharyn, Beyene, Joseph, Breau, Lynn, Camfield, Carol, Allen Finley, Gordon, Franck, Linda S., Howlett, Alexandra, Johnston, Celeste, McKeever, Patricia, O’Brien, Karel, Ohlsson, Arne, and Yamada, Janet
- Published
- 2009
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42. Family integrated care: very preterm neurodevelopmental outcomes at 18 months.
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Synnes, Anne R., Petrie, Julie, Grunau, Ruth E., Church, Paige, Kelly, Edmond, Moddemann, Diane, Xiang Ye, Shoo K. Lee, O'Brien, Karel, Ye, Xiang, Lee, Shoo K, Canadian Neonatal Network Investigators, and Canadian Neonatal Follow-Up Network Investigators
- Subjects
NEONATAL nursing ,PARENT attitudes ,SCHOOL children ,NEURAL development ,NEONATAL necrotizing enterocolitis ,PARENTING ,RESEARCH ,NEONATAL intensive care ,PSYCHOLOGY of parents ,CHILD development ,RESEARCH methodology ,NEONATAL intensive care units ,DEVELOPMENTAL disabilities ,EVALUATION research ,WORD deafness ,WEIGHT gain ,COMPARATIVE studies ,RANDOMIZED controlled trials ,BREASTFEEDING ,HEALTH care teams ,QUESTIONNAIRES ,PARENT-child relationships ,LONGITUDINAL method ,PSYCHOLOGICAL stress - Abstract
Objective: To examine whether the family integrated care (FICare) programme, a multifaceted approach which enables parents to be engaged as primary caregivers in the neonatal intensive care unit, impacts infant neurodevelopment and growth at 18 months' corrected age.Design/methods: Prospective cohort study of infants born <29 weeks' gestational age (GA) who participated in the FICare cluster randomised control trial (cRCT) and were assessed in the Canadian Neonatal Follow-Up Network (CNFUN). The primary outcome measure, Cognitive or Language composite score <85 on the Bayley-III, was compared between FICare exposed and routine care children using logistic regression, adjusted for potential confounders and employing generalised estimation equations to account for clustering of infants within sites.Results: Of 756 infants <29 weeks' GA in the FICare cRCT, 505 were enrolled in CNFUN and 455 were assessed (238 FICare, 217 control). Compared with controls, FICare infants had significantly higher incidence of intraventricular haemorrhage (IVH) (19.5% vs 11.7%, p=0.024) and higher proportion of employed mothers (76.6% vs 73.6%, p=0.043). There was no significant difference in the odds of the primary outcome (adjusted OR: 0.92 (0.59 to 1.42) FiCare vs Control) on multivariable analyses adjusted for GA, IVH and maternal employment. However, Bayley-III Motor scores (adjusted difference in mean (95% CI) 3.87 (1.22 to 6.53) and body mass index 0.67 (0.36 to 0.99) were higher in the FICare group.Conclusions: Very preterm infants exposed to FICare had no significant difference in incidence of cognitive or language delay but had better motor development.Trial Registration Number: Participants in this cohort study were previously enrolled in a registered trial: NCT01852695. [ABSTRACT FROM AUTHOR]- Published
- 2022
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43. Alpha1-proteinase inhibitor therapy for the prevention of chronic lung disease of prematurity: a randomized, controlled trial
- Author
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Stiskal, Joseph A., Dunn, Michael S., Shennan, Andrew T., O'Brien, Karel K.E., Kelly, Edmond N., Koppel, Robert I., Cox, Diane W., Ito, Shinya, Chappel, S. Lesley, and Rabinovitch, Marlene
- Subjects
Alpha 1-antitrypsin -- Health aspects ,Lung diseases -- Prevention ,Infants (Premature) -- Care and treatment - Abstract
Treating premature infants with alpha1-proteinase inhibitor (A1PI) may hinder the evolution of chronic lung disease (CLD) and reduce the risk of bleeding in the lungs. Of 106 low-birth-weight infants at high risk for this inflammatory lung disease, 53 were given four intravenous doses of A1PI between days 0 and 14, while the others received a placebo. No significant difference was seen between the groups with respect to CLD, measured as requiring oxygen therapy at day 28. The treated group showed improved outcomes in the reduction of pulmonary hemorrhage and days of oxygen therapy required., Background. An imbalance between increased neutrophil elastase and a decreased antiprotease shield has been suggested as a factor contributing to the development of chronic lung disease (CLD). We hypothesized that administration of [[Alpha].sub.1]-proteinase inhibitor (A1PI), also known as [[Alpha].sub.1]-antitrypsin, to premature neonates would prevent CLD. Design. A randomized, placebo-controlled, prospective study of A1PI supplementation was performed. Neonates [is less than] 24 hours of age with birth weights 600-1000 g on respiratory support, and 1001-1250 g with respiratory distress syndrome (RDS) were eligible. Intravenous A1PI (60 mg/kg) or placebo was infused on days 0, 4, 7, and 14. Primary outcome was CLD in survivors, defined as the need for supplemental oxygen on day 28. Results. A total of 106 patients were recruited. There were no significant differences between groups in birth weight or incidence of RDS. The incidence of CLD in survivors was lower in the treated group, but the difference did not reach statistical significance (relative risk [RR], 0.79; confidence interval [CI], 0.60-1.02). This beneficial trend persisted at 36 weeks corrected gestational age (RR, 0.48; CI, 0.23-1.00). The incidence of pulmonary hemorrhage was lower in the treated group (RR, 0.22; CI, 0.05-0.98). Other complications were not significantly different between groups. Conclusions. In this, the first trial of a protease inhibitor for the prevention of CLD in premature infants, the infusions were well-tolerated. A1PI therapy may impede the development of CLD and appears to reduce the incidence of pulmonary hemorrhage in some neonates born prematurely. Pediatrics 1998;101:89-94; [[Alpha].sub.1]-proteinase inhibitor, bronchopulmonary dysplasia, infant, randomized, controlled trials; serine proteinase inhibitors:, ABBREVIATIONS. CLD, chronic lung disease; RDS, respiratory distress syndrome; A1PI, [[Alpha].sub.1]-proteinase inhibitor. Chronic lung disease (CLD) or bronchopulmonary dysplasia is the end result of unresolved neonatal acute lung injury.[1] Affected [...]
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- 1998
44. A parent‐administered sensorimotor intervention for oral feeding in infants born preterm: A randomized clinical study.
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Fucile, Sandra, Snider, Laurie, O'Brien, Karel, Smith, Lorraine, and Dow, Kimberly
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NEONATAL intensive care units , *PREMATURE infants , *HOSPITAL admission & discharge , *DEVELOPMENTAL programs , *GESTATIONAL age - Abstract
Aim Method Results Interpretation To evaluate the effect of a parent‐administered sensorimotor intervention (PASI) program on developmental outcomes of infants born preterm during their stay in the neonatal intensive care unit (NICU).A randomized clinical study was conducted with 94 infants (mean gestational age 31 weeks [SD 2.2 weeks]; 1658 g [SD 478 g]; 49 males, 45 females) initially enrolled and randomly assigned to an experimental or a control group. Infants in the experimental group received a PASI, consisting of tactile input to oral structures, trunk/limbs, and non‐nutritive sucking for 15 minutes, once a day, for 10 days. Infants in the control group received standard care. Outcomes included attainment of complete oral feeds, occurrence of direct breastfeeding at hospital discharge, and motor function assessed using the Test of Infant Motor Performance (TIMP).A total of 80 infants completed the study. Infants in the experimental group achieved complete oral feeds sooner (11.9 [SD 4.3] vs 15.3 [SD 6.5] days, p = 0.013), and a greater number of them received direct breastfeeds (22 vs 12, p = 0.010) than controls. Infants in both groups had equivalent motor functions scores on the TIMP (46.9 [SD 4.8], 46.8 [SD 8.4], p = 0.961).A PASI program may enhance an infant's oral feeding skills. These findings provide evidence to advocate for the institution of PASI in NICUs. [ABSTRACT FROM AUTHOR]
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- 2024
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45. Procedural pain in newborns at risk for neurologic impairment
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Stevens, Bonnie, McGrath, Patrick, Gibbins, Sharyn, Beyene, Joseph, Breau, Lynn, Camfield, Carol, Finley, Allen, Franck, Linda, Howlett, Alixe, McKeever, Patricia, O'Brien, Karel, Ohlsson, Arne, and Yamada, Janet
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- 2003
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46. Supporting parents as essential care partners in neonatal units during the SARS-CoV-2 pandemic.
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Veenendaal, Nicole R., Deierl, Aniko, Bacchini, Fabiana, O'Brien, Karel, Franck, Linda S., van Veenendaal, Nicole R, and International Steering Committee for Family Integrated Care
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COVID-19 pandemic ,NEONATAL nursing ,PARENTS ,MEDICAL personnel ,PARENTING ,SARS-CoV-2 - Abstract
Aim: To review the evidence on safety of maintaining family integrated care practices and the effects of restricting parental participation in neonatal care during the SARS-CoV-2 pandemic.Methods: MEDLINE, EMBASE, PsycINFO and CINAHL databases were searched from inception to the 14th of October 2020. Records were included if they reported scientific, empirical research (qualitative, quantitative or mixed methods) on the effects of restricting or promoting family integrated care practices for parents of hospitalised neonates during the SARS-CoV-2 pandemic. Two authors independently screened abstracts, appraised study quality and extracted study and outcome data.Results: We retrieved 803 publications and assessed 75 full-text articles. Seven studies were included, reporting data on 854 healthcare professionals, 442 parents, 364 neonates and 26 other family members, within 286 neonatal units globally. The pandemic response resulted in significant changes in neonatal unit policies and restricting parents' access and participation in neonatal care. Breastfeeding, parental bonding, participation in caregiving, parental mental health and staff stress were negatively impacted.Conclusion: This review highlights that SARS-CoV-2 pandemic-related hospital restrictions had adverse effects on care delivery and outcomes for neonates, families and staff. Recommendations for restoring essential family integrated care practices are discussed. [ABSTRACT FROM AUTHOR]- Published
- 2021
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47. Family integrated care: Supporting parents as primary caregivers in the neonatal intensive care unit.
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Waddington, Chandra, Veenendaal, Nicole R., O'Brien, Karel, and Patel, Neil
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Family integrated care (FICare) is a collaborative model of neonatal care which aims to address the negative impacts of the neonatal intensive care unit (NICU) environment by involving parents as equal partners, minimizing separation, and supporting parent‐infant closeness. FICare incorporates psychological, educational, communication, and environmental strategies to support parents to cope with the NICU environment and to prepare them to be able to emotionally, cognitively, and physically care for their infant. FICare has been associated with improved infant feeding, growth, and parent wellbeing and self‐efficacy; important mediators for long‐term improved infant neurodevelopmental and behavioural outcomes. FICare implementation requires multi‐disciplinary commitment, staff motivation, and sufficient time for preparation and readiness for change as professionals relinquish power and control to instead develop collaborative partnerships with parents. Successful FICare implementation and culture change have been applied by neonatal teams internationally, using practical approaches suited to their local environments. Strategies such as parent and staff meetings and relational communication help to break down barriers to change by providing space for the co‐creation of knowledge, the negotiation of caregiving roles and the development of trusting relationships. The COVID‐19 pandemic highlighted the vulnerability within programs supporting parental presence in neonatal units and the profound impacts of parent‐infant separation. New technologies and digital innovations can help to mitigate these challenges, and support renewed efforts to embed FICare philosophy and practice in neonatal care during the COVID‐19 recovery and beyond. [ABSTRACT FROM AUTHOR]
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- 2021
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48. Effectiveness of Family Integrated Care in neonatal intensive care units on infant and parent outcomes: a multicentre, multinational, cluster-randomised controlled trial
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O'Brien, Karel, primary, Robson, Kate, additional, Bracht, Marianne, additional, Cruz, Melinda, additional, Lui, Kei, additional, Alvaro, Ruben, additional, da Silva, Orlando, additional, Monterrosa, Luis, additional, Narvey, Michael, additional, Ng, Eugene, additional, Soraisham, Amuchou, additional, Ye, Xiang Y, additional, Mirea, Lucia, additional, Tarnow-Mordi, William, additional, Lee, Shoo K, additional, O'Brien, Karel, additional, Lee, Shoo, additional, Caouette, Georges, additional, McMillan, Douglas, additional, Ly, Linh, additional, Dow, Kimberly, additional, Taylor, Richard, additional, Canning, Roderick, additional, Sankaran, Koravangattu, additional, Bingham, William, additional, el Helos, Salhab, additional, Osiovich, Horacio, additional, Emberley, Julie, additional, Catelin, Celine, additional, St. Aubin, Lucia, additional, Warkentin, Tammy, additional, Kalapesi, Zarin, additional, Bodani, Jaya, additional, Kho, Guan, additional, Kecskes, Zsuzsoka, additional, Stack, Jacqueline, additional, Schmidt, Peter, additional, Paradisis, Mary, additional, Broadbent, Roland, additional, Raiman, Clare, additional, Wong, Charlene, additional, Cabot, Michele, additional, L'Herault, Maryse, additional, Gignac, Marie-Andree, additional, Marquis, Marie-Helene, additional, Leblanc, Mylene, additional, Travell, Cathy, additional, Furlong, Marlene, additional, Van Bergen, Annette, additional, Ottenhof, Maryanne, additional, Keron, Heather, additional, Bowley, Clare, additional, Cross, Shannon, additional, Kozinka, Gillian, additional, Cobham-Richards, Valerie, additional, Northrup, Kelly, additional, Gilbert-Rogers, Cindy, additional, Pidgeon, Pat, additional, McDuff, Kim, additional, Leger, Norma, additional, Thiel, Cindy, additional, Willard, Shannon, additional, Ma, Evelyn, additional, Kostecky, Linda, additional, Pogorzelski, David, additional, Jacob, Sherin, additional, Kwiatkowski, Kim, additional, Cook, Valerie, additional, Granke, Naomi, additional, Geoghegan-Morphet, Nicola, additional, Bowell, Hannah, additional, Claydon, Jennifer, additional, Tucker, Nicole, additional, Lemaitre, Thomas, additional, Doyon, Myriam, additional, Ryan, Candace, additional, Sheils, Joanne, additional, Sibbons, Elizabeth, additional, Feary, Anne-Marie, additional, Callander, Ian, additional, Richard, Robyn, additional, Orbeso, Jennifer, additional, Broom, Margaret, additional, Fox, Alexis, additional, Seuseu, Jan, additional, Hourigan, Jack, additional, Schaeffer, Cynthia, additional, Mantha, Ginette, additional, Lataigne, Melanie, additional, Whitehead, Leah, additional, Skinner, Natasha, additional, Visconti, Rita, additional, Crosland, Deedee, additional, Griffin, Kate, additional, Griffin, Brandon, additional, Collins, Lisa, additional, Meyer, Kirsten, additional, Silver, Ian, additional, Burnham, Britt, additional, Freeman, Rachel, additional, Muralt, Kristi, additional, Ramsay, Cara, additional, McGrath, Pawulina, additional, Munroe, Michelle, additional, and Hales, Denise, additional
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- 2018
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49. Outcome following pulmonary haemorrhage in very low birthweight neonates treated with surfactant
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Pandit, Paresh B, O'Brien, Karel, Asztalos, Elizabeth, Colucci, Enza, and Dunn, Michael S
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- 1999
50. Infant flow biphasic nasal continuous positive airway pressure (BP- NCPAP) vs. infant flow NCPAP for the facilitation of extubation in infants' ≤ 1,250 grams: a randomized controlled trial
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O'Brien Karel, Campbell Craig, Brown Leanne, Wenger Lisa, and Shah Vibhuti
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Infant-newborn ,Non-invasive ventilation ,Continuous positive airway pressure ,Extubation failure ,Pediatrics ,RJ1-570 - Abstract
Abstract Background The use of mechanical ventilation is associated with lung injury in preterm infants and therefore the goal is to avoid or minimize its use. To date there is very little consensus on what is considered the "best non-invasive ventilation mode" to be used post-extubation. The objective of this study was to compare the effectiveness of biphasic nasal continuous positive airway pressure (BP-NCPAP) vs. NCPAP in facilitating sustained extubation in infants ≤ 1,250 grams. Methods We performed a randomized controlled trial of BP-NCPAP vs. NCPAP in infants ≤ 1,250 grams extubated for the first time following mechanical ventilation since birth. Infants were extubated using preset criteria or at the discretion of the attending neonatologist. The primary outcome was the incidence of sustained extubation for 7 days. Secondary outcomes included incidence of adverse events and short-term neonatal outcomes. Results Sixty-seven infants received BP-NCPAP and 69 NCPAP. Baseline characteristics were similar between groups. The trial was stopped early due to increased use of non-invasive ventilation from birth, falling short of our calculated sample size of 141 infants per group. The incidence of sustained extubation was not statistically different between the BP-NCPAP vs. NCPAP group (67% vs. 58%, P = 0.27). The incidence of adverse events and short-term neonatal outcomes were similar between the two groups (P > 0.05) except for retinopathy of prematurity which was noted to be higher (P = 0.02) in the BP-NCPAP group. Conclusions Biphasic NCPAP may be used to assist in weaning from mechanical ventilation. The effectiveness and safety of BP-NCPAP compared to NCPAP needs to be confirmed in a large multi-center trial as our study conclusions are limited by inadequate sample size. Clinical Trials Registration # NCT00308789 Source of support Grant # 06-06, Physicians Services Incorporated Foundation, Toronto, Canada. Summit technologies Inc. provided additional NCPAP systems and an unrestricted educational grant. Abstract presented at The Society for Pediatric Research Meeting, Baltimore, USA, May 2nd-5th, 2009 and Canadian Paediatric Society Meeting, June 23rd-29th, Ottawa, 2009.
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- 2012
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