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1. Pediatric HIV care and treatment services in Tanzania: implications for survival

Author

G Somi, M Majigo, J Manyahi, J Nondi, J Agricola, V Sambu, J Todd, A Rwebembera, N Makyao, A Ramadhani, and MIN Matee

Subjects
Children, HIV, Enrolment, ART, Care, Mortality, Public aspects of medicine, RA1-1270
Abstract

Abstract Background Improving child survival for HIV-infected children remains an important health agenda. We present progress regarding care and treatment services to HIV infected children in Tanzania. Methods The National AIDS Control Programme Care and Treatment (CTC 2) database was used to obtain information of all children aged 0-14yearsenrolled in the HIV Care and Treatment Program between January 2011 and December 2014. We assessed eligibility for ART, time from enrolment to ART initiation, nutritional status, and mortality using Kaplan-Meier methods. Results A total of 29,531 (14,304 boys and 15,227 girls) ART-naive children aged 0–14 years were enrolled during the period, approximately 6700 to 8000 children per year. The male to female ratio was 48:50. At enrolment 72% were eligible for ART, 2–3% of children were positive for TB, and 2–4% were severely malnourished. Between 2011 and 2014, 2368 (8%) died, 9243 (31%) were Lost to Follow-up and 17,920 (61%) were on care or ART. The probability of death was 31% (95% CI 26–35), 43% (40–47), 52% (49–55) and 61% (58–64) by 1,2, 5 and 10 years of age, respectively. The hazard of death was greatest at very young ages (

Published
2017
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2. Pediatric HIV care and treatment services in Tanzania: implications for survival

Author

Jim Todd, Min Matee, Angella Ramadhani, J Agricola, Veryhel Sambu, Mtebe Majigo, Neema Makyao, Anath Rwebembera, Joel Manyahi, Joseph Nondi, and Geoffrey Somi

Subjects
Male, Pediatrics, Databases, Factual, Survival, Human immunodeficiency virus (HIV), HIV Infections, Kaplan-Meier Estimate, Care, medicine.disease_cause, Tanzania, Health administration, 0302 clinical medicine, Health care, 030212 general & internal medicine, Child, Children, PMTCT (prevention of mother-to-child transmission), biology, lcsh:Public aspects of medicine, Health Policy, Nursing research, Health Services, Child, Preschool, Female, ART, Research Article, medicine.medical_specialty, Adolescent, Pediatric hiv, Anti-HIV Agents, 030231 tropical medicine, 03 medical and health sciences, Acquired immunodeficiency syndrome (AIDS), medicine, Humans, Mortality, Enrolment, business.industry, Public health, Infant, HIV, lcsh:RA1-1270, medicine.disease, biology.organism_classification, Survival Analysis, CD4 Lymphocyte Count, Treatment, Lost to Follow-Up, business
Abstract

Background Improving child survival for HIV-infected children remains an important health agenda. We present progress regarding care and treatment services to HIV infected children in Tanzania. Methods The National AIDS Control Programme Care and Treatment (CTC 2) database was used to obtain information of all children aged 0-14yearsenrolled in the HIV Care and Treatment Program between January 2011 and December 2014. We assessed eligibility for ART, time from enrolment to ART initiation, nutritional status, and mortality using Kaplan-Meier methods. Results A total of 29,531 (14,304 boys and 15,227 girls) ART-naive children aged 0–14 years were enrolled during the period, approximately 6700 to 8000 children per year. The male to female ratio was 48:50. At enrolment 72% were eligible for ART, 2–3% of children were positive for TB, and 2–4% were severely malnourished. Between 2011 and 2014, 2368 (8%) died, 9243 (31%) were Lost to Follow-up and 17,920 (61%) were on care or ART. The probability of death was 31% (95% CI 26–35), 43% (40–47), 52% (49–55) and 61% (58–64) by 1,2, 5 and 10 years of age, respectively. The hazard of death was greatest at very young ages (

Published
2017

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