4,359 results on '"Meiners, P"'
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2. Nachruf auf Prof. Dr. Dr. Hinderk Meiners Emrich (1943–2018)
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Schneider, Udo, Leweke, Markus, and Bleich, Stefan
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- 2019
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3. Davis, Angela. Y., Dent, Gina., Meiners, Erica. R., & Richie, Beth. E. (2022). Abolition. Feminism. Now. Chicago, Illinois: Haymarket Books. ISBN: 229 pp. 9781642592580
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Albano, Braelyn
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- 2023
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4. Donald J. Boudreaux and Roger Meiners (eds), The Legacy of Bruce Yandle. Arlington, VA: Mercatus center, 2020. xviii + 270 pages. USD 19.95 (paperback)
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Thomas, Michael David
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- 2022
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5. The Platonic Epistles and Fanaticism in the History of Philosophy: Meiners, Tiedemann, and Kant
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Osorio, Peter
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summary:In the early controversy over the Platonic Epistles, a certain type of argument for inauthenticity gained popularity: the character of Plato we find in them is unbefitting a philosopher, so the letters must be later forgeries. Despite the known limitations of this argument type, historians of philosophy in the late eighteenth century gradually extended its use to cases in which “Plato” seems to be a fanatic (Schwärmer), a contemporary slur leveled by sober professionals against amateur philosophers pretending to revelation. Given the shortcomings of this kind of argument from character, I aim to account for its popularization by placing it within larger disciplinary trends. Unlike other reasons for doubting authenticity (such as anachronism, inconsistency, and contradiction), the argument from character allows the critic to editorialize about philosophical norms. Accordingly, arguing from character in the context of the Epistles became a means of responding to Kant’s critical philosophy. This paper thus argues that a bad argument for the inauthenticity of the Platonic Epistles proliferated because it was useful for a proxy war over how to do philosophy in the context of a nascent and professionalizing discipline, the history of philosophy.
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- 2024
6. An Equitable Experience? How HCI Research Conceptualizes Accessibility of Virtual Reality in the Context of Disability
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Gerling, Kathrin, Meiners, Anna-Lena, Schumm, Louisa, Rixen, Jan, Wolf, Marvin, Yildiz, Zeynep, Alexandrovsky, Dmitry, and Opp, Merlin
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Computer Science - Human-Computer Interaction - Abstract
Creating accessible Virtual Reality (VR) is an ongoing concern in the Human-Computer Interaction (HCI) research community. However, there is little reflection on how accessibility should be conceptualized in the context of an experiential technology. We address this gap in our work: We first explore how accessibility is currently defined, highlighting a growing recognition of the importance of equitable and enriching experiences. We then carry out a literature study (N=28) to examine how accessibility and its relationship with experience is currently conceptualized in VR research. Our results show that existing work seldom defines accessibility in the context of VR, and that barrier-centric research is prevalent. Likewise, we show that experience - e.g., that of presence or immersion - is rarely designed for or evaluated, while participant feedback suggests that it is relevant for disabled users of VR. On this basis, we contribute a working definition of VR accessibility that considers experience a necessary condition for equitable access, and discuss the need for future work to focus on experience in the same way as VR research addressing non-disabled persons does.
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- 2024
7. Fabry-P\'{e}rot open resonant cavities for measuring the dielectric parameters of mm-wave optical materials
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Elwood, Brodi D., Grimes, Paul K., Kovac, John, Eiben, Miranda, and Meiners, Grant
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Physics - Optics ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
As millimeter-wave cosmology experiments refine their optical chains, precisely characterizing their optical materials under cryogenic conditions becomes increasingly important. For instance, as the aperture sizes and bandwidths of millimeter-wave receivers increase, the design of antireflection coatings becomes progressively more constrained by an accurate measure of material optical properties in order to achieve forecasted performance. Likewise, understanding dielectric and scattering losses is relevant to photon noise modeling in presently-deploying receivers such as BICEP Array and especially to future experiments such as CMB-S4. Additionally, the design of refractive elements such as lenses necessitates an accurate measure of the refractive index. High quality factor Fabry-P\'{e}rot open resonant cavities provide an elegant means for measuring these optical properties. Employing a hemispherical resonator that is compatible with a quick-turnaround 4 Kelvin cryostat, we can measure the dielectric and scattering losses of low-loss materials at both ambient and cryogenic temperatures. We review the design, characterization, and metrological applications of quasioptical cavities commissioned for measuring the dielectric materials in the BICEP3 (95 GHz) and BICEP Array mid-frequency (150 GHz) optics. We also discuss the efforts to improve the finesse of said cavities, for better resolution of degenerate higher order modes, which can provide stronger constraints on cavity parameters and sample material thickness., Comment: 12 pages, 4 figures
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- 2024
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8. Leveraging Virtual Reality Simulation to Engage Non-Disabled People in Reflection on Access Barriers for Disabled People
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Brogle, Timo, Ermoshkin, Andrej Vladimirovic, Vakhutinskiy, Konstantin, Priewe, Sven, Wittig, Claas, Meiners, Anna-Lena, Gerling, Kathrin, and Alexandrovsky, Dmitry
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Computer Science - Human-Computer Interaction ,H.5 - Abstract
Disabled people experience many barriers in daily life, but non-disabled people rarely pause to reflect and engage in joint action to advocate for access. In this demo, we explore the potential of Virtual Reality (VR) to sensitize non-disabled people to barriers in the built environment. We contribute a VR simulation of a major traffic hub in Karlsruhe, Germany, and we employ visual embellishments and animations to showcase barriers and potential removal strategies. Through our work, we seek to engage users in conversation on what kind of environment is accessible to whom, and what equitable participation in society requires. Additionally, we aim to expand the understanding of how VR technology can promote reflection through interactive exploration., Comment: Accepted at Mensch und Computer 2024 conference
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- 2024
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9. Church Philanthropy for Native Americans and Other Minorities: A Guide to Multicultural Funding from Religious Sources. Meiners' Multicultural Grant Guides. Native American Series.
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Meiners, Phyllis A. and Sanford, Greg A.
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This directory is organized into two sections covering grant and loan programs from religious sources that fund causes related to basic human need, social justice, and self-determination for economically deprived and diverse peoples. The first section describes 67 grant programs from 10 denominations (Baptist, Catholic, Christian Church: Disciples of Christ, Episcopal, Jewish, Lutheran, Methodist, Presbyterian, Unitarian, and United Church of Christ) and 3 ecumenical organizations (Church Women United, Commission on Religion in Appalachia, and Programme to Combat Racism). The second section contains 34 loan programs offered by eight denominations and a number of ecumenical organizations. For each program the following information is given, when available: complete address and phone number; denominational information such as branch, order, and headquarters; grant or loan dollar range; total annual grant or loan expenditures; fund governing body; grant making or loan committee(s); officers, committee members; special interests; geographic interests; application deadline; sample grants or loans; description and purpose; restrictions; and application procedures. In addition, three indexes list grant and loan programs by denomination; alphabetically; by geographic preference of giving (international, U.S. regional, state, or city); and by programs or subject areas of preferred giving. (TD)
- Published
- 1995
10. Active Brownian particle under stochastic orientational resetting
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Baouche, Yanis, Franosch, Thomas, Meiners, Matthias, and Kurzthaler, Christina
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Condensed Matter - Soft Condensed Matter ,Condensed Matter - Statistical Mechanics - Abstract
We employ renewal processes to characterize the spatiotemporal dynamics of an active Brownian particle under stochastic orientational resetting. By computing the experimentally accessible intermediate scattering function (ISF) and reconstructing the full time-dependent distribution of the displacements, we study the interplay of rotational diffusion and resetting. The resetting process introduces a new spatiotemporal regime reflecting the directed motion of agents along the resetting direction at large length scales, which becomes apparent in an imaginary part of the ISF. We further derive analytical expressions for the low-order moments of the displacements and find that the variance displays an effective diffusive regime at long times, which decreases for increasing resetting rates. At intermediate times the dynamics are characterized by a negative skewness as well as a non-zero non-Gaussian parameter.
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- 2024
11. Soil pooling often, but not always, alters the impacts of plant-microbe interactions on plant growth
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Clark, Kelly M., Earl, Allison G., Lopez, Isabella M., Meiners, Scott J., and Poland, Joshua C.
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- 2024
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12. Resolved-sideband cooling of a single $^9$Be$^+$ ion in a Penning trap
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Cornejo, Juan M., Brombacher, Johannes, Coenders, Julia A., von Boehn, Moritz, Meiners, Teresa, Niemann, Malte, Ulmer, Stefan, and Ospelkaus, Christian
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Physics - Atomic Physics ,Quantum Physics - Abstract
Manipulating individual trapped ions at the single quantum level has become standard practice in radio-frequency ion traps, enabling applications from quantum information processing to precision metrology. The key ingredient is ground-state cooling of the particle's motion through resolved-sideband laser cooling. Ultra-high-presicion experiments using Penning ion traps will greatly benefit from the reduction of systematic errors offered by full motional control, with applications to atomic masses and $g$-factor measurements, determinations of fundamental constants or related tests of fundamental physics. In addition, it will allow to implement quantum logic spectroscopy, a technique that has enabled a new class of precision measurements in radio-frequency ion traps. Here we demonstrate resolved-sideband laser cooling of the axial motion of a single $^9$Be$^+$ ion in a cryogenic 5 Tesla Penning trap system using a two-photon stimulated-Raman process, reaching a mean phonon number of $\bar{n}_z = 0.10(4)$. This is a fundamental step in the implementation of quantum logic spectroscopy for matter-antimatter comparison tests in the baryonic sector of the Standard Model and a key step towards improved precision experiments in Penning traps operating at the quantum limit., Comment: 6 pages, 5 figures
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- 2023
13. Fast adiabatic transport of single laser-cooled $^9$Be$^+$ ions in a cryogenic Penning trap stack
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Meiners, T., Coenders, J. -A., Mielke, J., Niemann, M., Cornejo, J. M., Ulmer, S., and Ospelkaus, C.
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Physics - Atomic Physics - Abstract
High precision mass and $g$-factor measurements in Penning traps have enabled groundbreaking tests of fundamental physics. The most advanced setups use multi-trap methods, which employ transport of particles between specialized trap zones. Present developments focused on the implementation of sympathetic laser cooling will enable significantly shorter duty cycles and better accuracies in many of these scenarios. To take full advantage of these increased capabilities, we implement fast adiabatic transport concepts developed in the context of trapped-ion quantum information processing in a cryogenic Penning trap system. We show adiabatic transport of a single $^9\mathrm{Be}^+$ ion initially cooled to 2 mK over a 2.2 cm distance within 15 ms and with less than 10\,mK energy gain at a peak velocity of 3 m/s. These results represent an important step towards the implementation of quantum logic spectroscopy in the \ppbar system. Applying these developments to other multi-trap systems has the potential to considerably increase the data-sampling rate in these experiments., Comment: 15 pages, 7 figures
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- 2023
14. Differential geometric bifurcation problems in pde2path -- algorithms and tutorial examples
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Meiners, Alexander and Uecker, Hannes
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Mathematics - Differential Geometry ,Mathematics - Analysis of PDEs ,Mathematics - Numerical Analysis ,65P30 - Abstract
We describe how some differential geometric bifurcation problems can be treated with the MATLAB continuation and bifurcation toolbox pde2path. The basic setup consists in solving the PDEs for the normal displacement of an immersed surface $X\subset\mathbb{R}^3$ and subsequent update of $X$ in each continuation step, combined with bifurcation detection and localization, followed by possible branch switching. Examples treated include some minimal surfaces such as Enneper's surface and a Schwarz-P-family, some non-zero constant mean curvature surfaces such as liquid bridges and nodoids, and some 4th order biomembrane models. In all of these we find interesting symmetry breaking bifurcations. Some of these are (semi)analytically known and thus are used as benchmarks.
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- 2023
15. Biodiversity of octopuses in the Americas
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González-Gómez, Roberto, Avendaño, Otilio, de los Angeles Barriga-Sosa, Irene, Bastos, Penélope, Caamal-Monsreal, Claudia, Castillo-Estrada, Gabriela, Cedillo-Robles, Celso, Daw, Adam, Díaz-Santana-Iturrios, Mariana, Galindo-Cortes, Gabriela, Guerrero-Kommritz, Jürgen, Haimovici, Manuel, Ibáñez, Christian M., de Lourdes Jiménez-Badillo, María, Larson, Paul, Leite, Tatiana, Lima, Françoise D., Markaida, Unai, Meiners-Mandujano, César, Morillo-Velarde, Piedad S., Ortiz, Nicolás, Pardo-Gandarillas, M. Cecilia, Pliego-Cárdenas, Ricardo, Ré, María Edith, Siegel, Brian, Urbano, Brian, Vidal, Erica A. G., and Gleadall, Ian G.
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- 2024
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16. First Nations Dance in the School Curriculum: Perspectives from an Australian University
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Rowlands, Kerrin, MacGill, Belinda, and Meiners, Jeff
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From the rallying call of the USA's Black Lives Matter movement, three Australian university teacher educators present perspectives on First Nations dance in the school curriculum. The Australian education system has emerged from the devastating impact of European colonisation upon the continent's First Nations peoples resulting in trauma, resistance, and resilience. Theory/praxis approaches to matters of Indigenous marginalisation within the school system are presented in relation to the context of public interest in "truth telling" about past colonial injustices. We draw first upon genealogical research to track the prohibition of Aboriginal dance in schools from the early years of colonisation to the later "White Australia" policy until now. Next, the complexities of embedding a new Aboriginal and Torres Strait Islander Histories and Cultures' Cross-Curriculum Priority are considered. Third, we explain research into teachers' enactment of First Nations dance in schools. Finally, a summary suggests ways forward from past wrongs.
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- 2022
17. Obituary for Professor Hinderk Meiners Emrich, MD PhD
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Leweke, F. Markus, Bleich, Stefan, and Schneider, Udo
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- 2018
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18. Optical stimulated-Raman sideband spectroscopy of a single $^9$Be$^+$ ion in a Penning trap
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Cornejo, J. M., Brombacher, J., Coenders, J. -A., von Boehn, M., Meiners, T., Niemann, M., Ulmer, S., and Ospelkaus, C.
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Physics - Atomic Physics - Abstract
We demonstrate optical sideband spectroscopy of a single $^9$Be$^+$ ion in a cryogenic 5 Tesla Penning trap using two-photon stimulated-Raman transitions between the two Zeeman sublevels of the $1s^{2}2s$ ground state manifold. By applying two complementary coupling schemes, we accurately measure Raman resonances with and without contributions from motional sidebands. From the latter we obtain an axial sideband spectrum with an effective mode temperature of (3.1 $\pm$ 0.4)~mK. This results are a key step for quantum logic operations in Pennings traps, applicable to high precision matter-antimatter comparisons tests in the baryonic sector of the standard model., Comment: 7 pages, 5 figures
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- 2023
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19. Bitter tastants relax the mouse gallbladder smooth muscle independent of signaling through tuft cells and bitter taste receptors
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Keshavarz, Maryam, Ruppert, Anna-Lena, Meiners, Mirjam, Poharkar, Krupali, Liu, Shuya, Mahmoud, Wafaa, Winterberg, Sarah, Hartmann, Petra, Mermer, Petra, Perniss, Alexander, Offermanns, Stefan, Kummer, Wolfgang, and Schütz, Burkhard
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- 2024
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20. Combined inhibition of EZH2 and CDK4/6 perturbs endoplasmic reticulum-mitochondrial homeostasis and increases antitumor activity against glioblastoma
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Freitag, Thomas, Kaps, Philipp, Ramtke, Justus, Bertels, Sarah, Zunke, Emily, Schneider, Björn, Becker, Anne-Sophie, Koczan, Dirk, Dubinski, Daniel, Freiman, Thomas M., Wittig, Felix, Hinz, Burkhard, Westhoff, Mike-Andrew, Strobel, Hannah, Meiners, Franziska, Wolter, Daniel, Engel, Nadja, Troschke-Meurer, Sascha, Bergmann-Ewert, Wendy, Staehlke, Susanne, Wolff, Annabell, Gessler, Florian, Junghanss, Christian, and Maletzki, Claudia
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- 2024
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21. Computational identification of natural senotherapeutic compounds that mimic dasatinib based on gene expression data
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Meiners, Franziska, Hinz, Burkhard, Boeckmann, Lars, Secci, Riccardo, Sueto, Salem, Kuepfer, Lars, Fuellen, Georg, and Barrantes, Israel
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- 2024
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22. Semiautomated approach focused on new genomic information results in time and effort-efficient reannotation of negative exome data
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Ferrer, Alejandro, Duffy, Patrick, Olson, Rory J., Meiners, Michael A., Schultz-Rogers, Laura, Macke, Erica L., Safgren, Stephanie, Morales-Rosado, Joel A., Cousin, Margot A., Oliver, Gavin R., Rider, David, Williams, Megan, Pichurin, Pavel N., Deyle, David R., Morava, Eva, Gavrilova, Ralitza H., Dhamija, Radhika, Wierenga, Klass J., Lanpher, Brendan C., Babovic-Vuksanovic, Dusica, Kaiwar, Charu, Vitek, Carolyn R., McAllister, Tammy M., Wick, Myra J., Schimmenti, Lisa A., Lazaridis, Konstantinos N., Vairo, Filippo Pinto e, and Klee, Eric W.
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- 2024
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23. Influence of Epoxy Spray Binder on Infusion and Cure in Liquid Composite Molding Processes
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Möllers, Hendrik, Schmidt, Carsten, and Meiners, Dieter
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- 2024
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24. Bitter tastants relax the mouse gallbladder smooth muscle independent of signaling through tuft cells and bitter taste receptors
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Maryam Keshavarz, Anna-Lena Ruppert, Mirjam Meiners, Krupali Poharkar, Shuya Liu, Wafaa Mahmoud, Sarah Winterberg, Petra Hartmann, Petra Mermer, Alexander Perniss, Stefan Offermanns, Wolfgang Kummer, and Burkhard Schütz
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Cholecystokinin ,Denatonium ,Dextromethorphan ,Taste transduction cascade ,Transient receptor potential family member 5 ,Quinine ,Medicine ,Science - Abstract
Abstract Disorders of gallbladder motility can lead to serious pathology. Bitter tastants acting upon bitter taste receptors (TAS2R family) have been proposed as a novel class of smooth muscle relaxants to combat excessive contraction in the airways and other organs. To explore whether this might also emerge as an option for gallbladder diseases, we here tested bitter tastants for relaxant properties and profiled Tas2r expression in the mouse gallbladder. In organ bath experiments, the bitter tastants denatonium, quinine, dextromethorphan, and noscapine, dose-dependently relaxed the pre-contracted gallbladder. Utilizing gene-deficient mouse strains, neither transient receptor potential family member 5 (TRPM5), nor the Tas2r143/Tas2r135/Tas2r126 gene cluster, nor tuft cells proved to be required for this relaxation, indicating direct action upon smooth muscle cells (SMC). Accordingly, denatonium, quinine and dextromethorphan increased intracellular calcium concentration preferentially in isolated gallbladder SMC and, again, this effect was independent of TRPM5. RT-PCR revealed transcripts of Tas2r108, Tas2r126, Tas2r135, Tas2r137, and Tas2r143, and analysis of gallbladders from mice lacking tuft cells revealed preferential expression of Tas2r108 and Tas2r137 in tuft cells. A TAS2R143-mCherry reporter mouse labeled tuft cells in the gallbladder epithelium. An in silico analysis of a scRNA sequencing data set revealed Tas2r expression in only few cells of different identity, and from in situ hybridization histochemistry, which did not label distinct cells. Our findings demonstrate profound tuft cell- and TRPM5-independent relaxing effects of bitter tastants on gallbladder smooth muscle, but do not support the concept that these effects are mediated by bitter receptors.
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- 2024
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25. Combined inhibition of EZH2 and CDK4/6 perturbs endoplasmic reticulum-mitochondrial homeostasis and increases antitumor activity against glioblastoma
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Thomas Freitag, Philipp Kaps, Justus Ramtke, Sarah Bertels, Emily Zunke, Björn Schneider, Anne-Sophie Becker, Dirk Koczan, Daniel Dubinski, Thomas M. Freiman, Felix Wittig, Burkhard Hinz, Mike-Andrew Westhoff, Hannah Strobel, Franziska Meiners, Daniel Wolter, Nadja Engel, Sascha Troschke-Meurer, Wendy Bergmann-Ewert, Susanne Staehlke, Annabell Wolff, Florian Gessler, Christian Junghanss, and Claudia Maletzki
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Here, we show that combined use of the EZH2 inhibitor GSK126 and the CDK4/6 inhibitor abemaciclib synergistically enhances antitumoral effects in preclinical GBM models. Dual blockade led to HIF1α upregulation and CalR translocation, accompanied by massive impairment of mitochondrial function. Basal oxygen consumption rate, ATP synthesis, and maximal mitochondrial respiration decreased, confirming disrupted endoplasmic reticulum-mitochondrial homeostasis. This was paralleled by mitochondrial depolarization and upregulation of the UPR sensors PERK, ATF6α, and IRE1α. Notably, dual EZH2/CDK4/6 blockade also reduced 3D-spheroid invasion, partially inhibited tumor growth in ovo, and led to impaired viability of patient-derived organoids. Mechanistically, this was due to transcriptional changes in genes involved in mitotic aberrations/spindle assembly (Rb, PLK1, RRM2, PRC1, CENPF, TPX2), histone modification (HIST1H1B, HIST1H3G), DNA damage/replication stress events (TOP2A, ATF4), immuno-oncology (DEPDC1), EMT-counterregulation (PCDH1) and a shift in the stemness profile towards a more differentiated state. We propose a dual EZH2/CDK4/6 blockade for further investigation.
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- 2024
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26. Hypersparse Network Flow Analysis of Packets with GraphBLAS
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Trigg, Tyler, Meiners, Chad, Pisharody, Sandeep, Jananthan, Hayden, Jones, Michael, Michaleas, Adam, Davis, Timothy, Welch, Erik, Arcand, William, Bestor, David, Bergeron, William, Byun, Chansup, Gadepally, Vijay, Houle, Micheal, Hubbell, Matthew, Klein, Anna, Michaleas, Peter, Milechin, Lauren, Mullen, Julie, Prout, Andrew, Reuther, Albert, Rosa, Antonio, Samsi, Siddharth, Stetson, Doug, Yee, Charles, and Kepner, Jeremy
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Computer Science - Networking and Internet Architecture ,Computer Science - Distributed, Parallel, and Cluster Computing - Abstract
Internet analysis is a major challenge due to the volume and rate of network traffic. In lieu of analyzing traffic as raw packets, network analysts often rely on compressed network flows (netflows) that contain the start time, stop time, source, destination, and number of packets in each direction. However, many traffic analyses benefit from temporal aggregation of multiple simultaneous netflows, which can be computationally challenging. To alleviate this concern, a novel netflow compression and resampling method has been developed leveraging GraphBLAS hyperspace traffic matrices that preserve anonymization while enabling subrange analysis. Standard multitemporal spatial analyses are then performed on each subrange to generate detailed statistical aggregates of the source packets, source fan-out, unique links, destination fan-in, and destination packets of each subrange which can then be used for background modeling and anomaly detection. A simple file format based on GraphBLAS sparse matrices is developed for storing these statistical aggregates. This method is scale tested on the MIT SuperCloud using a 50 trillion packet netflow corpus from several hundred sites collected over several months. The resulting compression achieved is significant (<0.1 bit per packet) enabling extremely large netflow analyses to be stored and transported. The single node parallel performance is analyzed in terms of both processors and threads showing that a single node can perform hundreds of simultaneous analyses at over a million packets/sec (roughly equivalent to a 10 Gigabit link)., Comment: arXiv admin note: text overlap with arXiv:2203.13934, arXiv:2108.06653, arXiv:2008.00307
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- 2022
27. Large Scale Enrichment and Statistical Cyber Characterization of Network Traffic (Enriquecimiento a gran escala y caracterizaci\'on cibern\'etica estad\'istica del tr\'afico de red)
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Kawaminami, Ivan, Estrada, Arminda, Elsakkary, Youssef, Jananthan, Hayden, Buluç, Aydın, Davis, Tim, Grant, Daniel, Jones, Michael, Meiners, Chad, Morris, Andrew, Pisharody, Sandeep, and Kepner, Jeremy
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Computer Science - Networking and Internet Architecture - Abstract
Modern network sensors continuously produce enormous quantities of raw data that are beyond the capacity of human analysts. Cross-correlation of network sensors increases this challenge by enriching every network event with additional metadata. These large volumes of enriched network data present opportunities to statistically characterize network traffic and quickly answer a key question: "What are the primary cyber characteristics of my network data?" The Python GraphBLAS and PyD4M analysis frameworks enable anonymized statistical analysis to be performed quickly and efficiently on very large network data sets. This approach is tested using billions of anonymized network data samples from the largest Internet observatory (CAIDA Telescope) and tens of millions of anonymized records from the largest commercially available background enrichment capability (GreyNoise). The analysis confirms that most of the enriched variables follow expected heavy-tail distributions and that a large fraction of the network traffic is due to a small number of cyber activities. This information can simplify the cyber analysts' task by enabling prioritization of cyber activities based on statistical prevalence. -- Los sensores de red modernos producen enormes cantidades de datos sin procesar que est\'an m\'as all\'a de la capacidad del an\'alisis humano. Una correlaci\'on cruzada de sensores de red se convierte en un desaf\'io al enriquecer cada evento de red con metadatos adicionales. Estos grandes vol\'umenes de datos de red enriquecidos presentan una oportunidad para caracterizar estad\'isticamente el tr\'afico de red y responder a la pregunta: "?Cu\'ales son las principales caracter\'isticas cibern\'eticas de mis datos de red?" Los esquemas de an\'alisis de Python GraphBLAS y D4M permiten realizar an\'alisis estad\'isticos an\'onimos, r\'apidos y eficientes en conjuntos grandes de datos de red. Este enfoque se prueba utilizando miles de millones de muestras de datos de red an\'onimos del observatorio de Internet m\'as grande (Telescopio CAIDA) y decenas de millones de registros an\'onimos del fondo comercial con la mayor capacidad de enriquecimiento (GreyNoise). El an\'alisis confirma que la mayor\'ia de las variables enriquecidas siguen las distribuciones de cola pesada y que una gran fracci\'on del tr\'afico de red se debe a una peque\`na cantidad de actividades cibern\'eticas. Esta informaci\'on puede simplificar la tarea de los analistas cibern\'eticos al permitir la priorizaci\'on de las actividades cibern\'eticas en funci\'on de la prevalencia estad\'istica., Comment: 17 pages, 16 figures, HPEC, Spanish version
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- 2022
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28. Speed Function for Biased Random Walks with Traps
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Betz, Volker, Meiners, Matthias, and Tomic, Ivana
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Mathematics - Probability ,Mathematical Physics ,60K37, 60F15 - Abstract
We consider a biased nearest-neighbor random walk on $\Z$ which at each step is trapped for some random time with random, site-dependent mean. We derive a simple formula for the speed function in terms of the model parameters., Comment: 10 pages, 3 figures
- Published
- 2022
29. Computational identification of natural senotherapeutic compounds that mimic dasatinib based on gene expression data
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Franziska Meiners, Burkhard Hinz, Lars Boeckmann, Riccardo Secci, Salem Sueto, Lars Kuepfer, Georg Fuellen, and Israel Barrantes
- Subjects
Medicine ,Science - Abstract
Abstract The major risk factor for chronic disease is chronological age, and age-related chronic diseases account for the majority of deaths worldwide. Targeting senescent cells that accumulate in disease-related tissues presents a strategy to reduce disease burden and to increase healthspan. The senolytic combination of the tyrosine-kinase inhibitor dasatinib and the flavonol quercetin is frequently used in clinical trials aiming to eliminate senescent cells. Here, our goal was to computationally identify natural senotherapeutic repurposing candidates that may substitute dasatinib based on their similarity in gene expression effects. The natural senolytic piperlongumine (a compound found in long pepper), and the natural senomorphics parthenolide, phloretin and curcumin (found in various edible plants) were identified as potential substitutes of dasatinib. The gene expression changes underlying the repositioning highlight apoptosis-related genes and pathways. The four compounds, and in particular the top-runner piperlongumine, may be combined with quercetin to obtain natural formulas emulating the dasatinib + quercetin formula.
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- 2024
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30. Taenia martis Neurocysticercosis-Like Lesion in Child, Associated with Local Source, the Netherlands
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Hendriekje Eggink, Miriam Maas, Judith M.A. van den Brand, Jasja Dekker, Frits Franssen, Eelco W. Hoving, Laetitia M. Kortbeek, Mariëtte E.G. Kranendonk, Linda C. Meiners, Anne E. Rittscher, Jeroen Roelfsema, and Elisabeth H. Schölvinck
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Neurocysticercosis ,Mustelidae ,Taenia ,Cestoda ,zoonoses ,parasites ,Medicine ,Infectious and parasitic diseases ,RC109-216 - Abstract
A neurocysticercosis-like lesion in an 11-year-old boy in the Netherlands was determined to be caused by the zoonotic Taenia martis tapeworm. Subsequent testing revealed that 15% of wild martens tested in that region were infected with T. martis tapeworms with 100% genetic similarity; thus, the infection source was most likely local.
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- 2024
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31. Angela Y. Davis, Gina Dent, Erica R. Meiners, and Beth E. Richie Abolition. Feminism. Now
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Reynolds, Holly
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- 2022
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32. Laminate polyethylene window development for large aperture millimeter receivers
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Eiben, Miranda, Barkats, Denis, Balkanski, Aurelia, Crystian, Sage, Dierickx, Marion I., Goldfinger, David C., Grimes, Paul K., Kimberk, Robert, Kovac, John M., Meiners, Grant, Petroff, Matthew A., Santalucia, Destiny, Sheffield, Elaine, Tsai, Calvin, and Villanueva, Natalia
- Subjects
Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
New experiments that target the B-mode polarization signals in the Cosmic Microwave Background require more sensitivity, more detectors, and thus larger-aperture millimeter-wavelength telescopes, than previous experiments. These larger apertures require ever larger vacuum windows to house cryogenic optics. Scaling up conventional vacuum windows, such as those made of High Density Polyethylene (HDPE), require a corresponding increase in the thickness of the window material to handle the extra force from the atmospheric pressure. Thicker windows cause more transmission loss at ambient temperatures, increasing optical loading and decreasing sensitivity. We have developed the use of woven High Modulus Polyethylene (HMPE), a material 100 times stronger than HDPE, to manufacture stronger, thinner windows using a pressurized hot lamination process. We discuss the development of a specialty autoclave for generating thin laminate vacuum windows and the optical and mechanical characterization of full scale science grade windows, with the goal of developing a new window suitable for BICEP Array cryostats and for future CMB applications.
- Published
- 2022
33. Fast adiabatic transport of single laser-cooled 9Be+ ions in a cryogenic Penning trap stack
- Author
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Meiners, Teresa, Coenders, Julia A., Brombacher, Johannes, Niemann, Malte, Cornejo, Juan M., Ulmer, Stefan, and Ospelkaus, Christian
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- 2024
- Full Text
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34. GraphBLAS on the Edge: Anonymized High Performance Streaming of Network Traffic
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Jones, Michael, Kepner, Jeremy, Andersen, Daniel, Buluc, Aydin, Byun, Chansup, Claffy, K, Davis, Timothy, Arcand, William, Bernays, Jonathan, Bestor, David, Bergeron, William, Gadepally, Vijay, Houle, Micheal, Hubbell, Matthew, Jananthan, Hayden, Klein, Anna, Meiners, Chad, Milechin, Lauren, Mullen, Julie, Pisharody, Sandeep, Prout, Andrew, Reuther, Albert, Rosa, Antonio, Samsi, Siddharth, Sreekanth, Jon, Stetson, Doug, Yee, Charles, and Michaleas, Peter
- Subjects
Computer Science - Networking and Internet Architecture ,Computer Science - Distributed, Parallel, and Cluster Computing ,Computer Science - Operating Systems ,Computer Science - Social and Information Networks - Abstract
Long range detection is a cornerstone of defense in many operating domains (land, sea, undersea, air, space, ..,). In the cyber domain, long range detection requires the analysis of significant network traffic from a variety of observatories and outposts. Construction of anonymized hypersparse traffic matrices on edge network devices can be a key enabler by providing significant data compression in a rapidly analyzable format that protects privacy. GraphBLAS is ideally suited for both constructing and analyzing anonymized hypersparse traffic matrices. The performance of GraphBLAS on an Accolade Technologies edge network device is demonstrated on a near worse case traffic scenario using a continuous stream of CAIDA Telescope darknet packets. The performance for varying numbers of traffic buffers, threads, and processor cores is explored. Anonymized hypersparse traffic matrices can be constructed at a rate of over 50,000,000 packets per second; exceeding a typical 400 Gigabit network link. This performance demonstrates that anonymized hypersparse traffic matrices are readily computable on edge network devices with minimal compute resources and can be a viable data product for such devices., Comment: Accepted to IEEE HPEC, Outstanding Paper Award, 8 pages, 8 figures, 1 table, 70 references. arXiv admin note: text overlap with arXiv:2108.06653, arXiv:2008.00307, arXiv:2203.10230
- Published
- 2022
- Full Text
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35. Temporal Correlation of Internet Observatories and Outposts
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Kepner, Jeremy, Jones, Michael, Andersen, Daniel, Buluç, Aydın, Byun, Chansup, Claffy, K, Davis, Timothy, Arcand, William, Bernays, Jonathan, Bestor, David, Bergeron, William, Gadepally, Vijay, Grant, Daniel, Houle, Micheal, Hubbell, Matthew, Jananthan, Hayden, Klein, Anna, Meiners, Chad, Milechin, Lauren, Morris, Andrew, Mullen, Julie, Pisharody, Sandeep, Prout, Andrew, Reuther, Albert, Rosa, Antonio, Samsi, Siddharth, Stetson, Doug, Yee, Charles, and Michaleas, Peter
- Subjects
Computer Science - Networking and Internet Architecture ,Computer Science - Distributed, Parallel, and Cluster Computing ,Computer Science - Social and Information Networks - Abstract
The Internet has become a critical component of modern civilization requiring scientific exploration akin to endeavors to understand the land, sea, air, and space environments. Understanding the baseline statistical distributions of traffic are essential to the scientific understanding of the Internet. Correlating data from different Internet observatories and outposts can be a useful tool for gaining insights into these distributions. This work compares observed sources from the largest Internet telescope (the CAIDA darknet telescope) with those from a commercial outpost (the GreyNoise honeyfarm). Neither of these locations actively emit Internet traffic and provide distinct observations of unsolicited Internet traffic (primarily botnets and scanners). Newly developed GraphBLAS hyperspace matrices and D4M associative array technologies enable the efficient analysis of these data on significant scales. The CAIDA sources are well approximated by a Zipf-Mandelbrot distribution. Over a 6-month period 70\% of the brightest (highest frequency) sources in the CAIDA telescope are consistently detected by coeval observations in the GreyNoise honeyfarm. This overlap drops as the sources dim (reduce frequency) and as the time difference between the observations grows. The probability of seeing a CAIDA source is proportional to the logarithm of the brightness. The temporal correlations are well described by a modified Cauchy distribution. These observations are consistent with a correlated high frequency beam of sources that drifts on a time scale of a month., Comment: 8 pages, 8 figures, 2 tables, 59 references; accepted to GrAPL 2022. arXiv admin note: substantial text overlap with arXiv:2108.06653
- Published
- 2022
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36. Book Review: Chemoecology of Insect Eggs and Egg Deposition. By Monika Hilker and Torsten Meiners (editors). Blackwell Publishing, Oxford. ISBN 1-4051-00087 $124.95 US, £60 UK
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McNeil, Jeremy N.
- Published
- 2003
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37. Roger E. Meiners and Andrew P. Morriss (Eds), The Common Law and the Environment: Rethinking the Statutory Basis for Modern Environmental Law
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Benson, Bruce L.
- Published
- 2001
- Full Text
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38. Spectral zeta function on discrete tori and Epstein-Riemann conjecture
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Meiners, Alexander and Vertman, Boris
- Subjects
Mathematics - Spectral Theory ,Mathematics - Differential Geometry ,52C05, 58J52, 65B15 - Abstract
We consider the combinatorial Laplacian on a sequence of discrete tori which approximate the m-dimensional torus. In the special case m=1, Friedli and Karlsson derived an asymptotic expansion of the corresponding spectral zeta function in the critical strip, as the approximation parameter goes to infinity. There, the authors have also formulated a conjecture on this asymptotics, that is equivalent to the Riemann conjecture. In this paper, inspired by the work of Friedli and Karlsson, we prove that a similar asymptotic expansion holds for m=2. Similar argument applies to higher dimensions as well. A conjecture on this asymptotics gives an equivalent formulation of the Epstein-Riemann conjecture, if we replace the standard discrete Laplacian with the $9$-point star discrete Laplacian., Comment: 37 pages, 2 figures
- Published
- 2022
39. Zero Botnets: An Observe-Pursue-Counter Approach
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Kepner, Jeremy, Bernays, Jonathan, Buckley, Stephen, Cho, Kenjiro, Conrad, Cary, Daigle, Leslie, Erhardt, Keeley, Gadepally, Vijay, Greene, Barry, Jones, Michael, Knake, Robert, Maggs, Bruce, Michaleas, Peter, Meiners, Chad, Morris, Andrew, Pentland, Alex, Pisharody, Sandeep, Powazek, Sarah, Prout, Andrew, Reiner, Philip, Suzuki, Koichi, Takahashi, Kenji, Tauber, Tony, Walker, Leah, and Stetson, Douglas
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Computer Science - Cryptography and Security ,Computer Science - Computers and Society ,Computer Science - Networking and Internet Architecture ,Computer Science - Social and Information Networks - Abstract
Adversarial Internet robots (botnets) represent a growing threat to the safe use and stability of the Internet. Botnets can play a role in launching adversary reconnaissance (scanning and phishing), influence operations (upvoting), and financing operations (ransomware, market manipulation, denial of service, spamming, and ad click fraud) while obfuscating tailored tactical operations. Reducing the presence of botnets on the Internet, with the aspirational target of zero, is a powerful vision for galvanizing policy action. Setting a global goal, encouraging international cooperation, creating incentives for improving networks, and supporting entities for botnet takedowns are among several policies that could advance this goal. These policies raise significant questions regarding proper authorities/access that cannot be answered in the abstract. Systems analysis has been widely used in other domains to achieve sufficient detail to enable these questions to be dealt with in concrete terms. Defeating botnets using an observe-pursue-counter architecture is analyzed, the technical feasibility is affirmed, and the authorities/access questions are significantly narrowed. Recommended next steps include: supporting the international botnet takedown community, expanding network observatories, enhancing the underlying network science at scale, conducting detailed systems analysis, and developing appropriate policy frameworks., Comment: 26 pages, 13 figures, 2 tables, 72 references, submitted to PlosOne
- Published
- 2022
40. Isolation and Characterization of Novel Oligomeric Proanthocyanidins in Chokeberries Using High-Resolution Mass Spectrometry and Investigation of Their Antioxidant Potential
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Amelie Meiners, Florian Hübner, and Melanie Esselen
- Subjects
oligomeric proanthocyanidins ,cinchonains ,TEAC assay ,modified DCFH2-DA assay ,antioxidant capacity ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Chokeberries, which belong to the rose family (Rosaceae), have received increasing research attention due to their high content of secondary metabolites, especially oligomeric proanthocyanidins (OPCs). OPC-rich extracts are attributed to various positive health effects, including antioxidant or anti-inflammatory properties, which is why they are sold as food supplements. However, knowledge about the antioxidant properties of single OPCs is quite limited. Several separation steps with different separation techniques were performed to isolate OPCs from a pre-produced extract. More than 90 analytes were detected in the enriched fractions, which include eight OPCs, four cinchonains and one hexoside, including their respective isomers. For the characterization of the OPCs, high-resolution mass spectrometry coupled with liquid chromatography (LC-HRMS) was used. Based on the fragment spectra of the MS2 experiments, conclusions about the fragmentation pathways and the structure of six new OPCs could be drawn. After isolating trimers, tetramers and pentamers, it was possible to test the antioxidant effect in relation to the individual degrees of polymerization (DP) or structures. The Trolox-equivalent antioxidant capacity (TEAC) test showed that all OPCs investigated exhibit antioxidant effects and a first correlation between the antioxidant effect and the DP could be postulated, which suggests new possibilities for the design of food supplements.
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- 2024
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41. Resolved-sideband cooling of a single ^{9}Be^{+} ion in a cryogenic multi-Penning-trap for discrete symmetry tests with (anti-)protons
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Juan M. Cornejo, Johannes Brombacher, Julia A. Coenders, Moritz von Boehn, Teresa Meiners, Malte Niemann, Stefan Ulmer, and Christian Ospelkaus
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Physics ,QC1-999 - Abstract
Manipulating the motion of individual trapped ions at the single quantum level has become standard practice in radio-frequency ion traps, enabling sweeping advances in quantum information processing and precision metrology. The key step for motional-state engineering is ground-state cooling. Full motional control also bears great potential to explore another regime of sensitivities for fundamental physics tests in Penning traps. Here we demonstrate the key enabling step by implementing resolved-sideband cooling on the axial mode of a single ^{9}Be^{+} ion in a 5 Tesla cryogenic Penning trap. The system has been developed for the implementation of high-precision antimatter experiments to test the fundamental symmetries of the standard model with the highest accuracy in the baryonic sector. We measure an axial phonon number of n[over ¯]_{z}=0.10(4) after cooling and demonstrate that the axial heating rate in our system is compatible with the implementation of quantum logic spectroscopy of (anti-)protons.
- Published
- 2024
- Full Text
- View/download PDF
42. Junior High School Students' Self-Confidence during Transition to Above-Grade-Level Mathematics Courses
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Schuh, Kathy L., Meiners, Amanda J., Ferguson, Cheryl, Hageman, Kara, George, Salim, Cox, Michala, Zou, Yuqing, and Lin, Chang-Jen
- Abstract
This qualitative study examined the mathematics self-confidence of eight junior high school students who were moved to an above-grade-level mathematics class through a nontraditional process. Teachers were concerned about how this transition may impact students' beliefs about their abilities to succeed in mathematics. Data were collected through interviews that included solving challenging mathematical tasks as a means to consider how students expressed their self-confidence in mathematics in general. Using a socio-constructivist lens with a focus on mediation, findings included themes about tensions given students' initial placement, changes in the role of self-confidence as a mediator, feelings of belonging as having multiple mediator roles, workarounds as mediators, and self-regulation strategies as internalized mediators that students brought with them to their transition. These findings point to solutions and supports for students who enroll in above-grade-level courses to view themselves as successful.
- Published
- 2023
- Full Text
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43. Realizing Forward Defense in the Cyber Domain
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Pisharody, Sandeep, Bernays, Jonathan, Gadepally, Vijay, Jones, Michael, Kepner, Jeremy, Meiners, Chad, Michaleas, Peter, Tse, Adam, and Stetson, Doug
- Subjects
Computer Science - Cryptography and Security - Abstract
With the recognition of cyberspace as an operating domain, concerted effort is now being placed on addressing it in the whole-of-domain manner found in land, sea, undersea, air, and space domains. Among the first steps in this effort is applying the standard supporting concepts of security, defense, and deterrence to the cyber domain. This paper presents an architecture that helps realize forward defense in cyberspace, wherein adversarial actions are repulsed as close to the origin as possible. However, substantial work remains in making the architecture an operational reality including furthering fundamental research cyber science, conducting design trade-off analysis, and developing appropriate public policy frameworks.
- Published
- 2021
44. Asymptotic fluctuations in supercritical Crump-Mode-Jagers processes
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Iksanov, Alexander, Kolesko, Konrad, and Meiners, Matthias
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Mathematics - Probability ,60J80 (Primary) 60F05, 60G44 (Secondary) - Abstract
Consider a supercritical Crump--Mode--Jagers process $(\mathcal Z_t^{\varphi})_{t \geq 0}$ counted with a random characteristic $\varphi$. Nerman's celebrated law of large numbers [Z. Wahrsch. Verw. Gebiete 57, 365--395, 1981] states that, under some mild assumptions, $e^{-\alpha t} \mathcal Z_t^\varphi$ converges almost surely as $t \to \infty$ to $aW$. Here, $\alpha>0$ is the Malthusian parameter, $a$ is a constant and $W$ is the limit of Nerman's martingale, which is positive on the survival event. In this general situation, under additional (second moment) assumptions, we prove a central limit theorem for $(\mathcal Z_t^{\varphi})_{t \geq 0}$. More precisely, we show that there exist a constant $k \in \mathbb N_0$ and a function $H(t)$, a finite random linear combination of functions of the form $t^j e^{\lambda t}$ with $\alpha/2 \leq \mathrm{Re}(\lambda)<\alpha$, such that $(\mathcal Z_t^\varphi - a e^{\alpha t}W -H(t))/\sqrt{t^k e^{\alpha t}}$ converges in distribution to a normal random variable with random variance. This result unifies and extends various central limit theorem-type results for specific branching processes., Comment: 67 pages, 3 figures; This is the revised version, incorporating suggestions from the referees reports. Accepted for publication in the Annals of Probability
- Published
- 2021
45. The importance of translational science within the respiratory field
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Silke Meiners, Niki L. Reynaert, Andreas M. Matthaiou, Rishi Rajesh, Engi Ahmed, Raquel Guillamat-Prats, Irene H. Heijink, and Sara Cuevas-Ocaña
- Subjects
Diseases of the respiratory system ,RC705-779 - Abstract
The Translational Science Working Group at the European Respiratory Society (ERS) aims to bridge the gap between basic and clinical science by providing a platform where scientists, clinicians and experts in the respiratory field can actively shape translational research. For the 2023 Congress, dedicated translational science sessions were created and sessions of interest to many assemblies from the clinical and the scientific point of view were tagged as translational sessions, attracting clinical and scientific experts to the same room to discuss relevant topics and strengthening translational efforts among all ERS assemblies.
- Published
- 2024
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46. Spatial Temporal Analysis of 40,000,000,000,000 Internet Darkspace Packets
- Author
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Kepner, Jeremy, Jones, Michael, Andersen, Daniel, Buluc, Aydin, Byun, Chansup, Claffy, K, Davis, Timothy, Arcand, William, Bernays, Jonathan, Bestor, David, Bergeron, William, Gadepally, Vijay, Houle, Micheal, Hubbell, Matthew, Klein, Anna, Meiners, Chad, Milechin, Lauren, Mullen, Julie, Pisharody, Sandeep, Prout, Andrew, Reuther, Albert, Rosa, Antonio, Samsi, Siddharth, Stetson, Doug, Tse, Adam, Yee, Charles, and Michaleas, Peter
- Subjects
Computer Science - Networking and Internet Architecture ,Computer Science - Distributed, Parallel, and Cluster Computing ,Computer Science - Performance ,Computer Science - Social and Information Networks - Abstract
The Internet has never been more important to our society, and understanding the behavior of the Internet is essential. The Center for Applied Internet Data Analysis (CAIDA) Telescope observes a continuous stream of packets from an unsolicited darkspace representing 1/256 of the Internet. During 2019 and 2020 over 40,000,000,000,000 unique packets were collected representing the largest ever assembled public corpus of Internet traffic. Using the combined resources of the Supercomputing Centers at UC San Diego, Lawrence Berkeley National Laboratory, and MIT, the spatial temporal structure of anonymized source-destination pairs from the CAIDA Telescope data has been analyzed with GraphBLAS hierarchical hypersparse matrices. These analyses provide unique insight on this unsolicited Internet darkspace traffic with the discovery of many previously unseen scaling relations. The data show a significant sustained increase in unsolicited traffic corresponding to the start of the COVID19 pandemic, but relatively little change in the underlying scaling relations associated with unique sources, source fan-outs, unique links, destination fan-ins, and unique destinations. This work provides a demonstration of the practical feasibility and benefit of the safe collection and analysis of significant quantities of anonymized Internet traffic., Comment: 8 pages, 9 figures, 2 tables, 43 references, accepted to IEEE HPEC 2021. arXiv admin note: substantial text overlap with arXiv:2008.00307
- Published
- 2021
- Full Text
- View/download PDF
47. Towards Quantum Logic Inspired Cooling and Detection for Single (Anti-)Protons
- Author
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Meiners, T., Niemann, M., Paschke, A. -G., Mielke, J., Idel, A., Borchert, M., Voges, K., Bautista-Salvador, A., Ulmer, S., and Ospelkaus, C.
- Subjects
Quantum Physics ,Physics - Atomic Physics - Abstract
We discuss laser-based and quantum logic inspired cooling and detection methods amenable to single (anti-)protons. These would be applicable e.g. in a g-factor based test of CPT invariance as currently pursued within the BASE collaboration. Towards this end, we explore sympathetic cooling of single (anti-)protons with atomic ions as suggested by Heinzen and Wineland (1990)., Comment: Presented at LEAP 2016 in Kanazawa, Japan
- Published
- 2021
- Full Text
- View/download PDF
48. Towards Sympathetic Cooling of Single (Anti-)Protons
- Author
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Meiners, T., Niemann, M., Mielke, J., Borchert, M., Pulido, N., Cornejo, J. M., Ulmer, S., and Ospelkaus, C.
- Subjects
Physics - Atomic Physics - Abstract
We present methods to manipulate and detect the motional state and the spin state of a single antiproton or proton which are currently under development within the BASE (Baryon Antibaryon Symmetry Experiment) collaboration. These methods include sympathetic laser cooling of a single (anti-)proton using a co-trapped atomic ion as well as quantum logic spectroscopy with the two particles and could be implemented within the collaboration for state preparation and state readout in the antiproton $g$-factor measurement experiment at CERN. In our project, these techniques shall be applied using a single $^9\text{Be}^+$ ion as the atomic ion in a Penning trap system at a magnetic field of 5 T. As an intermediate step, a controlled interaction of two beryllium ions in a double-well potential as well as sympathetic cooling of one ion by the other shall be demonstrated., Comment: Proceedings of the 13th International Conference on Low Energy Antiproton Physics (LEAP 2018) Paris, France, 12-16 March 2018
- Published
- 2021
- Full Text
- View/download PDF
49. Towards Sympathetic Laser Cooling and Detection of Single (Anti-)Proton
- Author
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Meiners, T., Niemann, M., Paschke, A. -G., Borchert, M., Idel, A., Mielke, J., Voges, K., Bautista-Salvador, A., Lehnert, R., Ulmer, S., and Ospelkaus, C.
- Subjects
Quantum Physics ,Physics - Atomic Physics - Abstract
Current experimental efforts to test the fundamental CPT symmetry with single (anti-)protons are progressing at a rapid pace but are hurt by the nonzero temperature of particles and the difficulty of spin state detection. We describe a laser-based and quantum logic inspired approach to single (anti-)proton cooling and state detection., Comment: Presented at the Seventh Meeting on CPT and Lorentz Symmetry, Bloomington, Indiana, June 20-24, 2016
- Published
- 2021
- Full Text
- View/download PDF
50. Cryogenic Penning-Trap Apparatus for Precision Experiments with Sympathetically Cooled (anti)protons
- Author
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Niemann, M., Meiners, T., Mielke, J., Pulido, N., Schaper, J., Borchert, M. J., Cornejo, J. M., Paschke, A. -G., Zarantonello, G., Hahn, H., Lang, T., Manzoni, C., Marangoni, M., Cerullo, G., Morgner, U., Fenske, J. -A., Bautista-Salvador, A., Lehnert, R., Ulmer, S., and Ospelkaus, C.
- Subjects
Physics - Atomic Physics ,Quantum Physics - Abstract
Current precision experiments with single (anti)protons to test CPT symmetry progress at a rapid pace, but are complicated by the need to cool particles to sub-thermal energies. We describe a cryogenic Penning-trap setup for $^9$Be$^+$ ions designed to allow coupling of single (anti)protons to laser-cooled atomic ions for sympathetic cooling and quantum logic spectroscopy. We report on trapping and laser cooling of clouds and single $^9$Be$^+$ ions. We discuss prospects for a microfabricated trap to allow coupling of single (anti)protons to laser-cooled $^9$Be$^+$ ions for sympathetic laser cooling to sub-mK temperatures on ms time scales., Comment: Presented at the Eighth Meeting on CPT and Lorentz Symmetry, Bloomington, Indiana, May 12-16, 2019
- Published
- 2021
- Full Text
- View/download PDF
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