39 results on '"Mahrhold, Stefan"'
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2. N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A
3. Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics
4. Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A
5. Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG‐Syt1‐SV2 plasma membrane nanocluster for synaptic vesicle entry
6. Functional detection of botulinum neurotoxin serotypes A to F by monoclonal neoepitope-specific antibodies and suspension array technology
7. Synaptotagmin 1 mediates toxicity of botulinum neurotoxin type A
8. Identification of the Protein Receptor Binding Site of Botulinum Neurotoxins B and G Proves the Double-Receptor Concept
9. Innovative and Highly Sensitive Detection of Clostridium perfringens Enterotoxin Based on Receptor Interaction and Monoclonal Antibodies
10. Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons
11. The 25 kDa HCN Domain of Clostridial Neurotoxins Is Indispensable for Their Neurotoxicity
12. Exchange of the HCC domain mediating double receptor recognition improves the pharmacodynamic properties of botulinum neurotoxin
13. The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites
14. Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor
15. Inhibition of exocytotic activity in human mast cell line 1 by clostridial neurotoxin light chains
16. Characterising and exploiting the binding of botulinum neurotoxins to their neuronal receptors
17. The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction
18. Super-resolving botulinum neurotoxin type A molecules: from surface landing to internalization in synaptic vesicles
19. Anthelmintic and anticonvulsive drugs do not alter the biological activity of BoNT in neurons
20. A lipid-binding loop of botulinum neurotoxin serotypes B, DC and G is an essential feature to confer their exquisite potency
21. Binding of botulinum neurotoxin (BoNT) to glycosylated SV2
22. Only the complex N559-glycan in the synaptic vesicle glycoprotein 2C mediates high affinity binding to botulinum neurotoxin serotype A1
23. Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin
24. 205. Characterizing the interaction of botulinum neurotoxin type A with rat and human SV2C
25. 132. Insights into the glycosylation-status dependent interaction of SV2C with botulinum neurotoxin type A
26. Identifizierung neuronaler Proteinrezeptoren clostridieller Neurotoxine
27. Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain
28. Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E
29. Botulinum Neurotoxin G Binds Synaptotagmin-II in a Mode Similar to That of Serotype B: Tyrosine 1186 and Lysine 1191 Cause Its Lower Affinity
30. Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner
31. Clostridial Neurotoxins: Mechanism of SNARE Cleavage and Outlook on Potential Substrate Specificity Reengineering
32. Characterising and exploiting the binding of botulinum neurotoxins to their neuronal receptors
33. Inhibition of exocytotic activity in human mast cell line 1 by clostridial neurotoxin light chains
34. The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves
35. The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction
36. Clint: A Novel Clathrin-binding ENTH-Domain Protein at the Golgi
37. Exchange of the HCC domain mediating double receptor recognition improves the pharmacodynamic properties of botulinum neurotoxin.
38. The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction.
39. The 25 kDa H CN Domain of Clostridial Neurotoxins Is Indispensable for Their Neurotoxicity.
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