28,253 results on '"M. H. Kim"'
Search Results
2. The CALIPSO version 4.5 stratospheric aerosol subtyping algorithm
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J. L. Tackett, J. Kar, M. A. Vaughan, B. J. Getzewich, M.-H. Kim, J.-P. Vernier, A. H. Omar, B. E. Magill, M. C. Pitts, and D. M. Winker
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Environmental engineering ,TA170-171 ,Earthwork. Foundations ,TA715-787 - Abstract
The accurate classification of aerosol types injected into the stratosphere is important to properly characterize their chemical and radiative impacts within the Earth climate system. The updated stratospheric aerosol subtyping algorithm used in the version 4.5 (V4.5) release of the Cloud Aerosol Lidar with Orthogonal Polarization (CALIOP) level 2 data products now delivers more comprehensive and accurate classifications than its predecessor. The original algorithm identified four aerosol subtypes for layers detected above the tropopause: volcanic ash, smoke, sulfate/other, and polar stratospheric aerosol (PSA). In the revised algorithm, sulfates are separately identified as a distinct, homogeneous subtype, and the diffuse, weakly scattering layers previously assigned to the sulfate/other class are recategorized as a fifth “unclassified” subtype. By making two structural changes to the algorithm and revising two thresholds, the V4.5 algorithm improves the ability to discriminate between volcanic ash and smoke from pyrocumulonimbus injections, improves the fidelity of the sulfate subtype, and more accurately reflects the uncertainties inherent in the classification process. The 532 nm lidar ratio for volcanic ash was also revised to a value more consistent with the current state of knowledge. This paper briefly reviews the previous version of the algorithm (V4.1 and V4.2) then fully details the rationale and impact of the V4.5 changes on subtype classification frequency for specific events where the dominant aerosol type is known based on the literature. Classification accuracy is best for volcanic ash due to its characteristically high depolarization ratio. Smoke layers in the stratosphere are also classified with reasonable accuracy, though during the daytime a substantial fraction are misclassified as ash. It is also possible for mixtures of ash and sulfate to be misclassified as smoke. The V4.5 sulfate subtype accuracy is less than that for ash or smoke, with sulfates being misclassified as smoke about one-third of the time. However, because exceptionally tenuous layers are now assigned to the unclassified subtype and the revised algorithm levies more stringent criteria for identifying an aerosol as sulfate, it is more likely that layers labeled as this subtype are in fact sulfate compared to those assigned the sulfate/other classification in the previous data release.
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- 2023
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3. Genistein and daidzein repress adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells via Wnt/β-catenin signalling or lipolysis M.-H. Kim et al. Anti-adipogenic effect of isoflavones.
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Kim, M.-H., Park, J.-S., Seo, M.-S., Jung, J.-W., Lee, Y.-S., and Kang, K.-S.
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GENISTEIN , *MESENCHYMAL stem cells , *LIPOLYSIS , *ISOFLAVONES , *OBESITY - Abstract
One aspect of the effects of isoflavones against fat deposition might be at least associated with the mechanism by which Wnt/β-catenin signalling inhibits adipocyte differentiation. However, it remains completely unknown as to whether isoflavones might influence Wnt signalling during commitment of pluripotent mesenchymal stem cells (MSCs) to adipose lineages. In the present study, we have investigated the mechanisms underlying effects of genistein and daidzein, the major soy isoflavones, on anti-adipogenic Wnt/β-catenin signalling. Adipose tissue-derived (AD) MSCs were exposed continuously to genistein and daidzein (0.01-100 μ) during adipogenic differentiation (21 days). An oestrogen antagonist, ICI 182,780, was used to determine whether or not the isoflavones activated Wnt signalling via oestrogen receptors (ERs). Genistein and daidzein suppressed adipogenic differentiation of AD-MSCs in a dose-dependent manner and inhibited expression of adipogenic markers, PPARγ, SREBP-1c and Glut 4, from mid-phase differentiation. Microarrays showed that anti-adipogenic effects of genistein were principally attributable to activation of Wnt signalling via ERs-dependent pathway, such as Erk/JNK signalling and LEF/TCF4 co-activators. These findings were supported by evidence that the effects of genistein were offset by ICI182,780. Unlike genistein, daidzein inhibited adipogenesis through stimulation of lipolysis, with for example, PKA-mediated hormone sensitive lipase. This is consistent with the increase in glycerol released from AD-MSCs. In conclusion, understanding that different sets of mechanisms of the two isoflavones on adipogenesis will help the design of novel strategies to prevent observed current epidemic levels of obesity, using isoflavones. [ABSTRACT FROM AUTHOR]
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- 2010
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4. Measurement of High-energy Cosmic-Ray Proton Spectrum from the ISS-CREAM Experiment
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G. H. Choi, E. S. Seo, S. Aggarwal, Y. Amare, D. Angelaszek, D. P. Bowman, Y. C. Chen, M. Copley, L. Derome, L. Eraud, C. Falana, A. Gerrety, J. H. Han, H. G. Huh, A. Haque, Y. S. Hwang, H. J. Hyun, H. B. Jeon, J. A. Jeon, S. Jeong, S. C. Kang, H. J. Kim, K. C. Kim, M. H. Kim, H. Y. Lee, J. Lee, M. H. Lee, L. Lu, J. P. Lundquist, L. Lutz, A. Menchaca-Rocha, O. Ofoha, H. Park, I. H. Park, J. M. Park, N. Picot-Clemente, R. Scrandis, J. R. Smith, R. Takeishi, N. Vedenkin, P. Walpole, R. P. Weinmann, H. Wu, J. Wu, Z. Yin, Y. S. Yoon, and H. G. Zhang
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- 2022
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5. The CALIPSO version 4 automated aerosol classification and lidar ratio selection algorithm
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M.-H. Kim, A. H. Omar, J. L. Tackett, M. A. Vaughan, D. M. Winker, C. R. Trepte, Y. Hu, Z. Liu, L. R. Poole, M. C. Pitts, J. Kar, and B. E. Magill
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Environmental engineering ,TA170-171 ,Earthwork. Foundations ,TA715-787 - Abstract
The Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP) version 4.10 (V4) level 2 aerosol data products, released in November 2016, include substantial improvements to the aerosol subtyping and lidar ratio selection algorithms. These improvements are described along with resulting changes in aerosol optical depth (AOD). The most fundamental change in the V4 level 2 aerosol products is a new algorithm to identify aerosol subtypes in the stratosphere. Four aerosol subtypes are introduced for stratospheric aerosols: polar stratospheric aerosol (PSA), volcanic ash, sulfate/other, and smoke. The tropospheric aerosol subtyping algorithm was also improved by adding the following enhancements: (1) all aerosol subtypes are now allowed over polar regions, whereas the version 3 (V3) algorithm allowed only clean continental and polluted continental aerosols; (2) a new dusty marine aerosol subtype is introduced, representing mixtures of dust and marine aerosols near the ocean surface; and (3) the polluted continental and smoke subtypes have been renamed polluted continental/smoke and elevated smoke, respectively. V4 also revises the lidar ratios for clean marine, dust, clean continental, and elevated smoke subtypes. As a consequence of the V4 updates, the mean 532 nm AOD retrieved by CALIOP has increased by 0.044 (0.036) or 52 % (40 %) for nighttime (daytime). Lidar ratio revisions are the most influential factor for AOD changes from V3 to V4, especially for cloud-free skies. Preliminary validation studies show that the AOD discrepancies between CALIOP and AERONET–MODIS (ocean) are reduced in V4 compared to V3.
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- 2018
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6. Development of a scintillator-based optical soft x-ray (OSXR) diagnostic system for KSTAR tokamak
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M. W. Lee, Junghee Kim, M. H. Kim, Soobin Lim, Jayhyun Kim, and C. Sung
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Instrumentation - Abstract
We have developed a new scintillator-based optical soft x-ray (OSXR) diagnostic system for KSTAR. By utilizing fiber optic faceplates, mm-size lens arrays, and fiber bundles, we have successfully constructed a novel optical system for scintillator-based soft x-ray detection to overcome the limited vacuum-port conditions in KSTAR. P47 (Y2SiO5), which has a fast rise (∼7 ns) and decay (∼100 ns) time sufficient for detecting plasma instabilities observed in the kHz–MHz spectral range, was selected as the scintillator material for the KSTAR OSXR system. Scintillation toward each detection channel is collected by the lens arrays coupled to optical fiber cores, which are connected to the photodetector system. Initial results obtained during the 2022 KSTAR experimental campaign support the validity of the OSXR data through the consistency of OSXR measurement results with other diagnostics. We also observe that the OSXR system can capture magnetohydrodynamic activities, such as sawtooth oscillations, and provide valuable information for disruption mitigation studies using shattered pellet injection.
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- 2023
7. The Influence of Neurological Disorders Before Cardiac Myxoma Surgery on the Rate of Postoperative Recurrences: Analysis of 317 Patients in a Single Center
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Byul Hee Yoon, Wonhyoung Park, Jae Sung Ahn, Jung Cheol Park, Joonho Byun, M. H. Kim, and Seungjoo Lee
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medicine.medical_specialty ,business.industry ,Incidence (epidemiology) ,Medical record ,Myxoma ,Disease ,medicine.disease ,Single Center ,Surgery ,Heart Neoplasms ,Postoperative Complications ,Aneurysm ,Recurrence ,cardiovascular system ,medicine ,Humans ,cardiovascular diseases ,Neurology (clinical) ,Nervous System Diseases ,Adverse effect ,business ,Retrospective Studies ,Rare disease - Abstract
Background and Purpose Cardiac myxoma is a very rare disease for which resection is the treatment gold standard. There are many neurologic manifestations associated with this disease, including embolic infarctions, arterial aneurysms, and brain metastatic myxomas, but few large-scale studies have addressed this. We here retrospectively analyzed the incidence, type, and prognosis of these neurologic disorders. Methods We enrolled 317 patients who received a cardiac myxoma resection between 2004 and 2019 at our institution. A retrospective review of the medical records and radiologic imaging was performed for each patient, and various clinical factors were compared and analyzed with regard to clinical outcomes and the incidence of adverse events. Results Patients with a neurologic disorder before surgery were found to be more likely to develop new postoperative neurologic complications (p = .003). Patients with neurologic disorder arising at any time before or after surgery had poorer outcomes (p Conclusion The clinical management of cardiac myxoma must take account of neurologic sequelae independently of the surgical intervention to remove the lesion. Cardiac myxoma patients with any neurologic disorder should undergo both neurosurgical follow-up as well as cardiac surgical follow-up, even if myxoma removal surgery has been performed. We suggest that that active neuroimaging during long term follow-up is essential in these cases.
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- 2022
8. A Burn-in Potential Region Detection Method for the OLED panel displays.
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M.-H. Kim, S.-H. Chae, and J.-S. Kim
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- 2018
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9. The Boronated Scintillator Detector of the ISS-CREAM Experiment
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Y Amare, T Anderson, D J Angelaszek, N Anthony, K Cheryian, G H Choi, M Copley, S Coutu, L Derome, L Eraud, L Hagenau, J H Han, H G Huh, Y S Hwang, H J Hyun, S Im, H B Jeon, J A Jeon, S Jeong, S C Kang, H J Kim, K C Kim, M H Kim, H Y Lee, J Lee, M H Lee, J Liang, J T Link, L Lu, L Lutz, A Menchaca-Rocha, T Mernik, John W Mitchell, S I Mognet, S Morton, M Nester, S Nutter, O Ofoha, H Park, I H Park, J M Park, N Picot-Clemente, R Quinn, E S Seo, J R Smith, P Walpole, R P Weinmann, J Wu, and Y S Yoon
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Astrophysics - Abstract
The Cosmic Ray Energetics And Mass for the International Space Station (ISS-CREAM) instrument is a next-generation experiment for the direct detection and study of cosmic-ray nuclei and electrons. With a long exposure in low Earth orbit, the experiment will determine the particle fluxes and spectral details of cosmic-ray nuclei from hydrogen to iron, over an energy range of about 10(exp 12) eV to > 10(exp 15) eV, and of cosmic-ray electrons over an energy range of about 5x10(exp 10) eV to > 10(exp 13) eV. The instrument was deployed to the ISS in August 2017 on the SpaceX CRS-12 mission. We review the design, implementation and performance of one of the ISS-CREAM detector systems: a boron loaded scintillation detector used in discriminating electron-induced events from the much more abundant cosmic-ray nuclei.
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- 2019
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10. Reusing hepatic grafts in Korea: a case report
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Hye Young Kim, Jeongrim Lee, M H Kim, YounJung Choi, Byunghyun Choi, and Wonhyun Cho
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medicine.medical_specialty ,business.industry ,Medicine ,business ,Surgery - Published
- 2021
11. All-fiber common-path fourier-domain optical coherence tomography moving 2-axis based on active surface tracking algorithm.
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C. G. Song, K. S. Kim, M. H. Kim, S. H. Ryu, J. H. Seo, and Jin U. Kang
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- 2011
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12. Effect of early hysterectomy on a risk of incident cardiovascular disease in women: a nationwide population-based cohort study
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B G Kim, J S Yuk, G S Kim, J K Seo, M N Jin, H Y Lee, Y S Seo, M H Kim, S W Yang, S H Yoon, Y S Byun, and B O Kim
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Cardiology and Cardiovascular Medicine - Abstract
Aim Women who inevitably underwent surgical hysterectomy before natural menopause may have an earlier increase in hematocrit and storage iron than women who continue menstruation, thereby increasing the risk of cardiovascular disease (CVD) early. We aimed to evaluate the association of women with hysterectomy vs. without hysterectomy before their 50s with the risk of incident CVD. Methods This was a retrospective-cohort study, 135,575 women aged 40 to 50 years in 2011–2014 were extracted from the Korean Health Insurance Review and Assessment Service data and after propensity score matching, 55,539 pairs were included in hysterectomy and non-hysterectomy group respectively. The primary endpoint was major adverse cardiac and cerebrovascular events (MACCE), a composite of cardiovascular death, myocardial infarction (MI), stroke, and coronary artery revascularization. Results After adjustment for confounding factors, hysterectomy group had an increased risk of MACCE compared with non-hysterectomy group (hazard ratio [HR], 1.25; 95% confidence interval [CI], 1.09–1.44). Regarding individual outcomes, cardiovascular death, MI, and coronary revascularization were comparable between the groups, whereas, the risk of stroke was significantly higher in hysterectomy group than non-hysterectomy group (HR, 1.31; 95% CI, 1.12–1.53). Even after excluding women who underwent oophorectomy, hysterectomy group had a higher risk of MACCE than non-hysterectomy group (HR, 1.24; 95% CI 1.06–1.44). Conclusions Early surgical menopause due to hysterectomy, not hormonal menopause, was associated with an increased risk for a composite of CVD, especially stroke. This suggest that the role of “uterus” as well as sex hormones may be important for the sharp increase in the risk of CVD in women after menopause. Funding Acknowledgement Type of funding sources: None.
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- 2022
13. Prognostic implication of platelet reactivity according to disease entity after drug eluting stent implantation: results from the PTRG-DES consortium
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P Hyun Woong, J Y H Jeong, K B K Kim, J H J Joo, P Y Park, C K Chang, S Y B Song, A S G Ahn, S J W Suh, L S Y Lee, C J R Cho, H S K Kim, K M H Kim, and S E S Shin
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Cardiology and Cardiovascular Medicine - Abstract
Background Relationship between the level of antiplatelet effect and clinical event appears weak in East Asian patients. In addition prognostic implication of platelet reactivity may differ according to index presentation of disease entity (AMI vs. non-AMI). Methods PTRG-PFT consortium was established to determine the linkage of platelet function with long-term clinical outcome during DAPT (aspirin+clopidogrel) in DES-treated East Asian patients (n=11,714). Platelet reactivity was measured using the VerifyNow P2Y12 assay and its level was divided according to quartile distribution (≤168, 169–220, 221–271, ≥272 P2Y12 reaction unit [PRU]). Primary endpoints were incidences of major adverse cardiac and cerebrovascular events (MACCE) post-PCI. Results Impact of platelet reactivity on MACCE occurrence appeared proportionally increased irrespective of type of disease entity, but their relationship was relatively stronger in the AMI vs. non-AMI group (Figure 1A and B). The cutoff of high-risk platelet reactivity was lower in the AMI group compared with the non-AMI group (225 vs. 245 PRU), and the cutoff of low-risk platelet reactivity (immunity zone) was similar between the groups (175 vs. 170 PRU). In the AMI patients (28.5%), 3rd and 4th quartiles significantly increased MACCE rate (HRadjusted 2.19 and 2.24) (Figure 1C and D). However, 4th quartile only was significantly associated with increased risk of MACCE among the non-AMI patients (71.5%) (HRadjusted 2.19). Conclusion Close associations between platelet reactivity and MACCE occurrence were observed irrespective of type of disease entity. In addition, the targeted antiplatelet level to prevent platelet-centric events appeared similar between the AMI and non-AMI patients. Funding Acknowledgement Type of funding sources: Foundation. Main funding source(s): Korean Society of Intervention Cardiology
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- 2022
14. Blunted atrial reverse remodeling a year after catheter ablation for atrial fibrillation and their long-term rhythm outcome
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M H Kim, I Hwang, J W Park, H T Yu, T H Kim, J S Uhm, B Joung, M H Lee, and H N Pak
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Cardiology and Cardiovascular Medicine - Abstract
Background Although active rhythm control by atrial fibrillation (AF) catheter ablation (AFCA) reduces left atrial (LA) dimension, blunted atrial reverse remodeling can be observed in patients with significant atrial myopathy. We explored the characteristics and long-term outcomes of AF patients who showed blunted atrial reverse remodeling despite no AF recurrence within a year after AFCA. Methods Among a total of 2,756 patients with AFCA, we included 1,685 patients (74.8% male, 60.2±10.1 years old, 54.5% paroxysmal AF) who underwent both baseline and 1-year follow-up echocardiogram, baseline LA>40mm, and did not recur within a year. We divided them into tertile groups (T1–T3) based on one-year percent change of LA dimension after propensity matching for age, sex, AF type, and baseline LA dimension. We also investigated the patients' genetic characteristics with blunted LA reverse remodeling (T1) using a genome-wide association study (GWAS). Results Patients with blunted LA reverse remodeling (T1, n=424) were independently associated with body mass index (OR 1.082 [1.010–1.160], p=0.025), LA peak pressure (OR 1.010 [1.002–1.019], p=0.019), LA wall thickness (OR 0.448 [0.252–0.789], p=0.006), LA voltage (OR 0.651 [0.463–0.907], p=0.012), and pericardial fat volume (OR 1.004 [1.001–1.008], p=0.014). Throughout 65.9±37.4 months of follow-up, the incidence of AF recurrence a year after the procedure was significantly higher in the T1 group than in T2 or T3 groups (Log-rank p Conclusions Patients with blunted LA reverse remodeling after AFCA were independently associated with low LA voltage, thin wall thickness, high LA pressure, and fat volume, and have a genetic background. Long-term clinical recurrence a year after AFCA was higher in this patient group with suspicious atrial myopathy. Funding Acknowledgement Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Ministry of Health and WelfareNational Research Foundation of Korea
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- 2022
15. Continuous Real-Time Ambulatory Urodynamic Monitoring Using Personal Digital Assistance.
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K.-S. Kim, S. H. Yu, M. H. Kim, D. H. Shin, and C. G. Song
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- 2010
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16. Development and validation of a risk scoring model for postoperative adult moyamoya disease
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Wonhyoung Park, Jung Cheol Park, M. H. Kim, Seungjoo Lee, Si Un Lee, Do Hoon Kwon, Yeongu Chung, and Jae Sung Ahn
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Adult ,Male ,medicine.medical_specialty ,Multivariate analysis ,Hyperlipidemias ,Neuroimaging ,Comorbidity ,Models, Biological ,Risk Assessment ,Cigarette Smoking ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Risk Factors ,Modified Rankin Scale ,Internal medicine ,Diabetes Mellitus ,medicine ,Humans ,Generalizability theory ,Moyamoya disease ,Family history ,Stroke ,Retrospective Studies ,Cerebral Revascularization ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,Cerebral Angiography ,Treatment Outcome ,ROC Curve ,030220 oncology & carcinogenesis ,Cohort ,Female ,Moyamoya Disease ,business ,030217 neurology & neurosurgery - Abstract
OBJECTIVE The current grading system for moyamoya disease (MMD) is focused on angiographic studies with limited clinical application. The authors aimed to determine relevant factors that may impact postoperative outcome and establish a scoring system to predict the functional outcome. METHODS Adult patients with MMD who underwent treatment between 1998 and 2016 were included. Factors such as age, sex, comorbidity, smoking, MMD family history, initial presentation, multimodal imaging modalities, and types of surgical revascularization were thoroughly reviewed. These factors were analyzed to determine possible risk factors related to unfavorable 6-month postoperative outcomes using the modified Rankin Scale (mRS) (unfavorable: mRS score ≥ 3). A scoring system was developed using these independent risk factors to predict the outcome and validated using prospectively collected data from multiple centers between 2017 and 2018. RESULTS Of 302 patients for whom applications were submitted, 260 patients (321 hemispheres) met the diagnostic criteria. In multivariate analysis, hyperlipidemia, smoking, cerebral infarction on preoperative CT or MRI, and moderately to severely reduced regional cerebrovascular reserve results from Diamox SPECT were significantly related to unfavorable outcome. The authors developed a scoring system and stratified patients into risk groups according to their scores: low-risk (score 0–3), intermediate-risk (score 4–6), and high-risk (score 7–9) groups. This model demonstrated both good discrimination and calibration using C-statistics and the Hosmer-Lemeshow goodness-of-fit test showing 0.812 (95% CI 0.743–0.881) (p = 0.568) for the development and 0.954 (95% CI 0.896–1) (p = 0.097) for the temporal and external validation cohort. CONCLUSIONS The authors’ scoring system is readily adoptable to predict the postoperative outcome for MMD. Their data revealed the importance of smoking and hyperlipidemia, which were the only modifiable factors included in the scoring system. The authors validated their scoring system both internally and externally and maintained good performance, highlighting the system’s generalizability and reliability.
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- 2021
17. First observation and interpretation of spontaneous collective radiation from fusion-born ions in a stellarator plasma
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B C G Reman, R O Dendy, H Igami, T Akiyama, M Salewski, S C Chapman, J W S Cook, S Inagaki, K Saito, R Seki, M Toida, M H Kim, S G Thatipamula, and G S Yun
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Large helical device ,Nuclear Energy and Engineering ,Hybrid kinetic modelling ,Ion cyclotron emission ,Fusion-born ions ,High performance computing ,Condensed Matter Physics ,Heliotron stellarator ,QC - Abstract
During bursty MHD events, transient ion cyclotron emission (ICE) is observed from deuterium plasmas in the large helical device (LHD) heliotron-stellarator. Unusually, the frequencies of the successive ICE spectral peaks are not close to integer multiples of the local cyclotron frequency of an energetic ion population in the likely emitting region. We show that this ICE is probably driven by a subset of the fusion-born protons near their birth energy E H = 3.02 MeV. This subset has a kinetic energy component parallel to the magnetic field, m H v ∥ 2 / 2 , significantly greater than its perpendicular energy m H v ⊥ 2 / 2 , for which v ⊥ ∼ V A , the Alfvén speed. First principles computations of the collective relaxation of this proton population, within a majority thermal deuterium plasma, are carried out using a particle-in-cell approach. This captures the full gyro-orbit kinetics of all ions which, together with an electron fluid, evolve self-consistently with the electric and magnetic fields under the Maxwell–Lorentz equations. The simulated ICE spectra are derived from the Fourier transform of the fields which are excited. We find substantial frequency shifts in the peaks of the simulated ICE spectra, which correspond closely to the measured ICE spectra following the resonance condition ω = k ∥ v ∥ + n Ω H for nth proton harmonic. This suggests that the transient ICE in LHD is generated by the identified subset of the fusion-born protons, relaxing under the magnetoacoustic cyclotron instability. So far as is known, this is the first report of a collective radiation signal from fusion-born ions in anon-tokamak magnetically confined plasma. Disambiguation between two or more energetic ion species that could potentially generate complex observed ICE spectra is an increasing challenge, and the results and methodology developed here will assist this. Our approach is also expected to be relevant to ICE driven by ion beams with lower parallel velocities, for example in cylindrical plasma experiments.
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- 2022
18. Brief Report: Development of App-based CBT Program for Depressive College Students: Mind Booster Green
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M. H. Kim and K. M. Chung
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- 2022
19. On the submicron aerosol distributions and CCN number concentrations in and around the Korean Peninsula
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J. H. Kim, S. S. Yum, S. Shim, W. J. Kim, M. Park, J.-H. Kim, M.-H. Kim, and S.-C. Yoon
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Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Total number concentrations of particles having a diameter larger than 10 nm (NCN), cloud condensation nuclei at several supersaturation (S) values (NCCN) and number size distributions of particles with 10–414 nm diameter were measured in Seoul between 2004 and 2010. Overall average values of NCN and geometric mean diameter were 17 811 ± 5581 cm−3 and 48 ± 6 nm. Average NCCN at 0.4, 0.6 and 0.8% S were 4145 ± 2016, 5323 ± 2453 and 6067 ± 2780 cm−3 and corresponding NCCN / NCN were 0.26 ± 0.11, 0.33 ± 0.11 and 0.37 ± 0.12. There is a clear seasonal variation in aerosol concentration, which seems to be due to the monsoon. NCN and NCCN are also found to depend on the volume of traffic and the height of the planetary boundary layer, respectively. During aircraft campaigns in 2009 and 2011, NCN and NCCN at 0.6% S (N0.6%) were measured in and around the Korean Peninsula. During the 2011 campaign, the aerosol scattering coefficient was also measured. NCN and N0.6% in the lower altitudes were generally higher than at higher altitudes, except for cases when particle formation and growth events were thought to occur at higher altitudes. NCN and N0.6% generally show a positive correlation with aerosol scattering coefficients but this correspondence tends to vary with altitude. Occasional instances of low (< 0.3) N0.6% / NCN in the boundary layer are demonstrated to be associated with particle formation and growth events. With the support of ground measurements, it is confirmed that a particle formation and growth event did indeed occur over the Yellow Sea on a flight day, and the areal extent of this event is estimated to be greater than 100 km × 450 km. With the combination of the current and several relevant previous studies, a composite map of NCN and NCCN in and around the Korean Peninsula is produced. Overall, the exhibited concentrations are typical of values measured over polluted regions elsewhere on the globe. Moreover, there is a generally decreasing trend from west to east over the region, implying that the region is constantly under the dominant influence of continental outflow.
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- 2014
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20. Clinical case of CNS-involved refractory thrombotic thrombocytopenic purpura
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M. H. Kim, Seungjoo Lee, and Minhan Kim
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medicine.medical_specialty ,Refractory ,business.industry ,Cerebral infarction ,Internal medicine ,medicine.medical_treatment ,medicine ,Thrombotic thrombocytopenic purpura ,Plasmapheresis ,Clinical case ,business ,medicine.disease ,Gastroenterology - Published
- 2021
21. A Prognostic Model of Pontine Hemorrhage Based on Hemorrhage Volume and Location
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Jae Sung Ahn, Wonhyoung Park, M. H. Kim, Minhan Kim, Seung Hoon You, Su-Hee Cho, Seungjoo Lee, Jung Cheo Park, and Ji Eun Park
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medicine.medical_specialty ,Pontine hemorrhage ,business.industry ,Prognostic model ,Medicine ,Radiology ,business ,Volume (compression) - Published
- 2021
22. Reactive Oxygen Species Scavenger in Acute Intracerebral Hemorrhage Patients
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Joonho Byun, Jae Sung Ahn, Ji Eun Park, Si Un Lee, M. H. Kim, Wonhyoung Park, Seungjoo Lee, Yeongu Chung, and Jung Cheol Park
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Adult ,Male ,medicine.disease_cause ,law.invention ,Selenium ,03 medical and health sciences ,0302 clinical medicine ,Hematoma ,Randomized controlled trial ,law ,Edema ,Humans ,Medicine ,Cerebral Hemorrhage ,Advanced and Specialized Nursing ,Intracerebral hemorrhage ,chemistry.chemical_classification ,Reactive oxygen species ,business.industry ,030208 emergency & critical care medicine ,Free Radical Scavengers ,Middle Aged ,medicine.disease ,Scavenger (chemistry) ,Acetylcysteine ,Oxidative Stress ,Treatment Outcome ,chemistry ,Anesthesia ,Female ,Neurology (clinical) ,medicine.symptom ,Reactive Oxygen Species ,Cardiology and Cardiovascular Medicine ,business ,030217 neurology & neurosurgery ,Oxidative stress - Abstract
Background and Purpose: Patients with intracerebral hemorrhage (ICH) have oxidative stress. Oxidative stress contributes to the development and progression of perihematomal edema (PHE) in brain hemorrhage patients. We hypothesized that reactive oxygen species (ROS) scavengers might have a neuroprotective role in the acute period of patients with ICH. Methods: This prospective, multicenter, single-blind, randomized study was conducted between June 2017 and October 2019. Intracranial bleeding, including spontaneous ICH, secondary ICH due to vascular anomalies, venous thrombosis, neoplasms, or hemorrhagic infarction, were included in our study. These ROS scavengers were given for 14 days with a dose of N-acetylcysteine 2000 mg/d and selenium 1600 µg/d intravenously. Other patients received a placebo. The primary outcome was hemorrhage and PHE volume changes in 2-week follow-up computed tomography between ROS scavenger versus placebo groups. Results: In total, 448 patients were enrolled with 123 patients remaining after applying the inclusion and exclusion criteria. There were no significant differences in baseline characteristics between the ROS scavenger (n=57) and placebo (n=66) groups. No significant differences in baseline hematoma and PHE volumes were observed but 2 weeks follow-up computed tomography showed significant differences in PHE volume (21.90±17.63 versus 30.66±32.35, P P P P Conclusions: ROS scavenger showed a significantly reduced PHE volume, time to reach target Richmond Agitation Sedation Scale, and shortened length of intensive care unit stay in patients with acute ICH. Early and high doses of ROS scavengers in a combination regimen may have played a key role in obtaining a favorable outcome in our study. Registration: URL: https://cris.nih.go.kr/cris/en ; Unique identifier: KCT0004628.
- Published
- 2021
23. Design and Performance Evaluatiojn of Webbased DRM System using Real-time Fingerprints Recognition Mechanism.
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Y.-K. Kang, P.-J. Kwon, and M.-H. Kim
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- 2003
24. System Implementation of DRM using Realtime Automatic Fingerprints Recognition Mechanism.
- Author
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Y.-K. Kang, P.-J. Kwon, and M.-H. Kim
- Published
- 2003
25. The mvprotek : m-commerce voice verification system.
- Author
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Y. J. Kyung, J. O. Jung, S. M. Sohn, H. J. Chun, S. Y. Moon, M. H. Kim, and W. H. Sull
- Published
- 2001
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26. Digital Contents Protection System Design with Real-time Fingerprints Recognition Mechanism.
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Y.-K. Kang and M.-H. Kim
- Published
- 2001
27. ENDOSCOPIC ULTRASOUND-GUIDED THROUGH-THE-NEEDLE MICROFORCEP BIOPSY IMPROVES THE CATEGORIZATION OF THE TYPE OF PANCREATIC CYSTIC LESIONS
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S.H. Cho, T.J. Song, D.-W. Seo, D. Oh, D.H. Park, S.S. Lee, S.K. Lee, and M.-H. Kim
- Published
- 2022
28. Effects of Synchronicity of Carbohydrate and Protein Degradation on Rumen Fermentation Characteristics and Microbial Protein Synthesis
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J. K. Seo, M. H. Kim, J. Y. Yang, H. J. Kim, C. H. Lee, K. H. Kim, and Jong K. Ha
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Enzyme ,Formaldehyde ,Synchronicity ,Rumen Fermentation ,Microbial Protein Synthesis ,Animal culture ,SF1-1100 ,Animal biochemistry ,QP501-801 - Abstract
A series of in vitro studies were carried out to determine i) the effects of enzyme and formaldehyde treatment on the degradation characteristics of carbohydrate and protein sources and on the synchronicity of these processes, and ii) the effects of synchronizing carbohydrate and protein supply on rumen fermentation and microbial protein synthesis (MPS) in in vitro experiments. Untreated corn (C) and enzyme-treated corn (EC) were combined with soy bean meal with (ES) and without (S) enzyme treatment or formaldehyde treatment (FS). Six experimental feeds (CS, CES, CFS, ECS, ECES and ECFS) with different synchrony indices were prepared. Highly synchronous diets had the greatest dry matter (DM) digestibility when untreated corn was used. However, the degree of synchronicity did not influence DM digestibility when EC was mixed with various soybean meals. At time points of 12 h and 24 h of incubation, EC-containing diets showed lower ammonia-N concentrations than those of C-containing diets, irrespective of the degree of synchronicity, indicating that more efficient utilization of ammonia-N for MPS was achieved by ruminal microorganisms when EC was offered as a carbohydrate source. Within C-containing treatments, the purine base concentration increased as the diets were more synchronized. This effect was not observed when EC was offered. There were significant effects on VFA concentration of both C and S treatments and their interactions. Similar to purine concentrations, total VFA production and individual VFA concentration in the groups containing EC as an energy source was higher than those of other groups (CS, CES and CFS). The results of the present study suggested that the availability of energy or the protein source are the most limiting factors for rumen fermentation and MPS, rather than the degree of synchronicity.
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- 2013
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29. Factors Affecting the Time Taken to Determine Brain Death in Patients with Impending Brain Death
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Wonhyun Cho, Young-Soo Kim, Dohyung Kim, Tae-Won Yang, Jeongrim Lee, M H Kim, and Oh-Young Kwon
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Pediatrics ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,organ transplantation ,craniotomy ,Mean age ,Organ transplantation ,Transplantation ,03 medical and health sciences ,0302 clinical medicine ,Neurology ,medicine ,brain death ,In patient ,Original Article ,030212 general & internal medicine ,Neurology (clinical) ,Organ donation ,movement ,business ,030217 neurology & neurosurgery ,Craniotomy ,time - Abstract
Background and purpose The increased demand for donor organs has made it crucial to keep the organs of patients with impending brain death (PWIBDs) suitable for transplantation during the process of determining brain death. This study aimed to identify the time taken to determine brain death (TT-BD) in PWIBDs and the associated influencing factors. Methods This study analyzed data collected by the Korean Organ Donation Agency from 15 hospitals in the Yeongnam region of South Korea. There were 414 PWIBDs eligible for inclusion in this study. The data consisted of the TT-BD for PWIBDs and the potential variables influencing the TT-BD. Results The mean age of the 414 PWIBDs was 48.9 years, and 120 of them were female (29.0%). The mean TT-BD was 8.5 days. The presence of spontaneous movements (SMs) and craniotomy significantly affected the TT-BD. The mean TT-BDs were 13.9 and 8.2 days in the PWIBDs with and without SMs, respectively, and 9.8 and 8.0 days in the PWIBDs with and without craniotomy, respectively. Conclusions The SMs in PWIBDs and a craniotomy performed immediately before starting the process of determining brain death seem to be related to lengthening the TT-BD.
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- 2020
30. Role of gamma knife radiosurgery for recurrent or residual World Health Organization grade II and III intracranial meningiomas
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Chang Jin Kim, M. H. Kim, Do Hoon Kwon, Young Hyun Cho, Jeong Hoon Kim, and Sung Woo Roh
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Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Gamma knife radiosurgery ,Gamma knife ,Radiosurgery ,World Health Organization ,World health ,Meningioma ,03 medical and health sciences ,0302 clinical medicine ,Meningeal Neoplasms ,medicine ,Humans ,Aged ,Retrospective Studies ,business.industry ,Role ,General Medicine ,Middle Aged ,medicine.disease ,Treatment Outcome ,030220 oncology & carcinogenesis ,Female ,Surgery ,Neurology (clinical) ,Radiology ,Neoplasm Recurrence, Local ,business ,030217 neurology & neurosurgery ,Follow-Up Studies - Abstract
Background: To analysis the role of gamma knife radiosurgery (GKRS) in treatment of the recurrent or residual World Health Organization (WHO) grade II and III meningiomas.Methods: Between 1995 and ...
- Published
- 2020
31. Reflex and Spontaneous Movements of Patients in the Process of Determining Brain Death
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Do-Hyung Kim, Youngsoo Kim, Oh-Young Kwon, Soo-Kyoung Kim, Juhyeon Kim, Won Hyun Cho, Jeongrim Lee, Tae-Won Yang, and M H Kim
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business.industry ,Movement (music) ,Spontaneous movements ,Reflex ,Medicine ,business ,Process (anatomy) ,Neuroscience - Published
- 2019
32. Status and Prospects of the LHCf and RHICf experiments
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Yuki Shimizu, Yoshitaka Itow, Byungsik Hong, Kenta Sato, S. B. Ricciarini, Takashi Sako, Shoji Torii, Paolo Papini, Y. Goto, I. Nakagawa, M. Ueno, M. H. Kim, R. Seidl, Massimo Bongi, Raffaello D'Alessandro, Eugenio Berti, W. C. Turner, Alessia Tricomi, Moe Kondo, Hiroaki Menjo, Kiyoshi Tanida, Ken Ohashi, Yasushi Muraki, Katsuaki Kasahara, T. Tamura, Alessio Tiberio, G. Castellini, Maurice Haguenauer, Kenji Yoshida, Yutaka Matsubara, Lorenzo Bonechi, Nobuyuki Sakurai, and O. Adriani
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Physics ,Physics::Instrumentation and Detectors ,High Energy Physics::Experiment ,Detectors and Experimental Techniques ,Nuclear Experiment ,Particle Physics - Experiment - Abstract
Precise understanding of hadronic interactions at high energies is a key to improve mass composition measurements of very high energy cosmic-rays and to solve the muon excess issue observed in high energy cosmic-ray experiments using an air-shower technique. The LHCf and RHICf experiments measures the differential production cross sections of very forward neutral particle as photons, neutral pions and neutrons at LHC and RHIC, respectively. These data are critically important to test and tune hadronic interaction models used for air-shower simulations. In this presentation, we introduce the recent results of both the experiments as well as our future operation plans. LHCf published an updated result of forward neutron measurement at pp, $\sqrt{s}$ = 13 TeV. From the observed neutron energy spectra, we also obtained the average inelasticity, which is one of the key parameters for air shower development, as 0.536 +0.031-0.037. In addition, several analysis are on-going; neutral pion measurement at pp, $\sqrt{s}$ = 13 TeV, central- forward correlation analysis with LHCf+ATLAS, photon measurement by RHICf. LHCf plans to have operations at $pp$ and $p$O during the LHC-Run3 period. At pp collisions, new silicon readout system will be introduced to improve the read-out speed, and 10 times more statistics of the previous operation in 2015 will be obtained. Thanks to high statistics, rare particles such as $\eta$, $K^0_s$ and $\Lambda$ will be addressed also. We also plan another operation at RHIC in 2024 with a new detector. The detector, a calorimeter composed of tungsten, Si pad and pixel layers, will have a much wider acceptance and higher sensitivity of $K^0_s$ measurement than the current detector.
- Published
- 2021
33. An Artificial Intelligence Algorithm-Based Smartphone Application Can Help to Monitor Cough in Real Time
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M.-S. Yang, B.-K. Kim, M.-H. Kim, S.-H. Kim, C. Song, S.-Y. Kang, J.-W. Kwon, J.-S. Shim, S.M. Lee, H.-K. Park, M.R. Sher, and H.-W. Park
- Subjects
Computer science ,Real-time computing ,Smartphone application - Published
- 2021
34. Parallel algorithm for traveling salesman problem on SIMD machines using simulated annealing.
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C. S. Jeong and M. H. Kim
- Published
- 1990
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35. A knowledge and data base for software systems.
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Luis Miguel, M. H. Kim, and C. V. Ramamoorthy
- Published
- 1990
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36. Fast parallel simulated annealing for traveling salesman problem.
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C. S. Jeong and M. H. Kim
- Published
- 1990
- Full Text
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37. Efficacy and Safety of Honey Bee Venom (Apis mellifera) Dermal Injections to Treat Osteoarthritis Knee Pain and Physical Disability: A Randomized Controlled Trial
- Author
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Christopher M H Kim, Vicki J Conrad, Anna Jakubowska, Lydie L Hazan, and Agustin J Latorre
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medicine.medical_specialty ,animal structures ,Physical disability ,business.industry ,fungi ,food and beverages ,Venom ,Honey bee ,Osteoarthritis ,Physical function ,medicine.disease ,complex mixtures ,law.invention ,Honey bee venom ,Knee pain ,Complementary and alternative medicine ,Randomized controlled trial ,law ,Internal medicine ,behavior and behavior mechanisms ,medicine ,medicine.symptom ,business - Abstract
Objectives: To evaluate purified honey bee (Apis mellifera) venom (HBV) biotherapy for the treatment of osteoarthritis (OA) knee pain and physical function. Design and Patients: Five hundr...
- Published
- 2019
38. Pediatric Intracranial Aneurysms: Favorable Outcomes Despite Rareness and Complexity
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M. H. Kim, Seungjoo Lee, Byung Duk Kwun, Jae Sung Ahn, Jung Cheol Park, Do Hoon Kwon, Wonhyoung Park, and Heui Seung Lee
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Male ,medicine.medical_specialty ,Adolescent ,Ruptured aneurysms ,Glasgow Outcome Scale ,Aneurysm, Ruptured ,Neurosurgical Procedures ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Aneurysm ,medicine.artery ,medicine ,Humans ,Initial treatment ,Endovascular treatment ,Child ,Retrospective Studies ,business.industry ,Incidence (epidemiology) ,Intracranial Aneurysm ,medicine.disease ,Surgery ,Child, Preschool ,030220 oncology & carcinogenesis ,Cohort ,Female ,Neurology (clinical) ,Internal carotid artery ,business ,Carotid Artery, Internal ,030217 neurology & neurosurgery - Abstract
Objective Pediatric intracranial aneurysms (IAs) are rare and differ from their adult counterparts in terms of their aneurysmal characteristics, presentation, treatment, and outcomes. Their treatment is often more difficult and complex compared with that of adults. However, studies outlining the clinical effect of pediatric IAs remain sparse. Methods We retrospectively reviewed the data from patients aged ≤18 years admitted to our hospital from 2000 to 2017 with a diagnosis of IAs. Results From the sample of 8207 patients with an IA diagnosis, 26 patients with 33 IAs were involved. Our cohort included 17 males and 9 females, with a mean age of 12.5 years. The mean follow-up duration was 4 years and 3 months. Seven patients (26.92%) were assumed to have a traumatic origin for their IAs. Ruptured aneurysms were more common than unruptured ones (61.53% vs. 38.46%). Complex features were observed in 14 aneurysms (42.42%). Initially, microsurgical and endovascular treatment were both performed in 10 patients (38.46%). A good recovery was obtained in 16 patients (61.54%) as determined by the Glasgow outcome scale scores at the 6-month follow-up visits. The complete obliteration of aneurysms was observed in 17 patients (65.38%). Endovascular treatment was the initial treatment in 3 patients with incomplete obliteration. Conclusions The treatment of pediatric IAs is challenging and technically demanding owing to their discrete nature compared with adult IAs and the need for greater surgical skills. We found a male predominance, with internal carotid artery bifurcation as the most frequent location of the aneurysms. Despite the greater incidence of ruptured and complex aneurysm cases, many patients had experienced a good recovery at the 6-month follow-up examinations.
- Published
- 2019
39. Performance of prototype neutron detectors for Large Acceptance Multi-Purpose Spectrometer at RAON
- Author
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H. H. Shim, Gyeonghwan Bak, H. S. Lee, Young Jun Kim, M. H. Kim, Byungsik Hong, Young-Jin Kim, B. Mulilo, Kyong Sei Lee, M. S. Ryu, Jamin Jo, Jung Keun Ahn, Jong Won Lee, Hanseul Lee, and Dong Ho Moon
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Physics ,Nuclear and High Energy Physics ,Spectrometer ,010308 nuclear & particles physics ,Astrophysics::High Energy Astrophysical Phenomena ,Nuclear Theory ,Scintillator ,Neutron radiation ,01 natural sciences ,Nuclear physics ,0103 physical sciences ,Physics::Accelerator Physics ,Incident energy ,Neutron detection ,High Energy Physics::Experiment ,Neutron ,Cosmic muons ,Nuclear Experiment ,010306 general physics ,Instrumentation - Abstract
The performance of the prototype modules of neutron detectors for the Large Acceptance Multi-Purpose Spectrometer (LAMPS) was investigated, using cosmic muons and neutron beams at 65 and 392 MeV, provided by the Research Center for Nuclear Physics (RCNP). The timing and position resolutions were estimated using cosmic muons as 309 ps and 4.8 cm, respectively. The energy resolution depended on the incident energy of neutrons: 1.3% at 65 MeV and 3.1% at 392 MeV. The neutron-detection efficiency also showed weak energy dependence as it decreased from (9.0 ± 1.6)% at 65 MeV to (6.3 ± 1.0)% at 392 MeV.
- Published
- 2019
40. Impact of leader‐member‐exchange and team‐member‐exchange on nurses’ job satisfaction and turnover intention
- Author
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Y.‐J. Yi and M.‐H. Kim
- Subjects
Adult ,Male ,Attitude of Health Personnel ,Interprofessional Relations ,media_common.quotation_subject ,Personnel Turnover ,Organizational culture ,Job Satisfaction ,InformationSystems_GENERAL ,03 medical and health sciences ,0302 clinical medicine ,Nursing ,Republic of Korea ,Humans ,Quality (business) ,030212 general & internal medicine ,Cooperative Behavior ,General Nursing ,media_common ,ComputingMilieux_THECOMPUTINGPROFESSION ,030504 nursing ,Multilevel model ,Attendance ,Middle Aged ,Organizational Culture ,ComputingMilieux_GENERAL ,Leadership ,Job performance ,Turnover intention ,Female ,Job satisfaction ,Descriptive research ,0305 other medical science ,Psychology - Abstract
Aim To investigate the impacts of leader-member exchange and team-member exchange on job satisfaction and turnover intention of nurses. Background Leader-member exchange refers to the quality of relationships between leaders and members of a team and studies on this have generally focused on the aspect of member-leader-member exchanges. In nursing, the latter can refer to a situation where nurses (members) evaluate their relationship with their head nurse (leader). Member-leader-member exchange affects job satisfaction and turnover intention of nurses. However, even though all of these types of exchanges are important, few studies have examined their effects on job satisfaction and the turnover intention of nurses. Methods Participants in this descriptive study were 40 head nurses and 284 clinical nurses working at three hospitals in Korea. Data were collected from a questionnaire and analysed using hierarchical multiple regression. Results Leader-leader-member exchange, member-leader-member exchange, and team-member exchange had a positive effect on job satisfaction. However, only leader-leader-member exchange and member-leader-member exchange affected turnover intention. Conclusions The impacts of leader-leader-member exchange, team-member exchange, and member-leader-member exchange on job satisfaction were confirmed. To reduce turnover intention, our study found it is more important to improve leader-member exchange than team-member exchange. Implications for nursing practice In health organizations, there is an important need to focus on the communication and exchange relationships between leaders and their staff, well as among the members, to increase job satisfaction. This will assist leaders to play an important role in lowering nurses' turnover intention and create an organizational culture in which nurses can communicate well with them. Implications for nursing policy Policy changes are needed so that the components of job performance evaluation for nurse leaders also include attendance at regular programmes, such as training to improve their leadership and communication skills, and consultations with their staff members.
- Published
- 2018
41. J-PARC E07: Systematic Study of Double Strangeness System with Hybrid Emulsion Method
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Megumi Naruki, R. Kiuchi, Kazuya Watanabe, S. H. Hwang, A. Koshikawa, Y. Sasaki, J. W. Lee, K. Ito, A. Iskendir, Yuki Sato, A. N. L. Nyaw, T. Nanamura, T. Takeda, Shoichi Hasegawa, S. Y. Matsumoto, Junya Yoshida, Yuki Fujikawa, M. Ichikawa, Masahiro Yoshimoto, Manabu Moritsu, Takayoshi Kawai, Hiroki Ito, K. Miwa, Hitoshi Takahashi, Y. Ogura, Hiroyuki Ekawa, C. S. Yoon, K. Imai, K. Inaba, D. H. Zhang, H. Kanauchi, W. S. Jung, Yoshiro Takahashi, Hitoshi Sugimura, Kazuma Nakazawa, T. Hashimoto, Manami Fujita, J. Y. Sohn, Jihwa Lee, Shunsuke Kanatsuki, K. Tanida, H. Sako, T. L. Ma, T. Hayakawa, A. T. Moe, M. Hirose, S. Kinbara, D. Nakashima, M. H. Kim, K. Oue, Y. Nakada, T. J. Moon, M. Minakawa, Myint Kyaw Soe, T. Takahashi, K. Agari, E. Umezaki, Toyoki Watabe, Seongbae Yang, S. Ashikaga, Y. C. Han, Yoshikazu Ishikawa, Mifuyu Ukai, M. Ohashi, Masaharu Ieiri, Kazuhiro Suzuki, Aye Moh Moh Theint, Kensuke Kobayashi, M. M. Soe, K. Hosomi, Manami Nakagawa, K. Hicks, S. Hoshino, Kotaro Shirotori, Yuya Akazawa, S. Y. Ryu, S. H. Kim, E. Hayata, B. Bassalleck, A. Kasagi, Z. Zhang, J. K. Ahn, J. Pochodzalla, Khin Than Tint, Shuhei Hayakawa, T. O. Yamamoto, Takeshi Koike, Y. Toyama, S. Sato, S. Ozawa, N. Fujioka, Ryotaro Honda, Yoko Endo, Y. Ichikawa, T. Akaishi, K. Hoshino, Erina Hirose, S. Bleser, Y. Nagase, Hitoshi Tamura, F. Schupp, Hidetaka Kobayashi, and R. Goto
- Subjects
Nuclear physics ,Physics ,Emulsion ,J-PARC ,Strangeness - Published
- 2021
42. Observation of Coulomb-Assisted Nuclear Bound State of Ξ−–N14 System
- Author
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S. Bleser, Hitoshi Sugimura, S H Hayakawa, T. Takeda, T. L. Ma, H. Kanauchi, D. H. Zhang, Junya Yoshida, T. Hayakawa, Z. Zhang, Khin Than Tint, M. Minakawa, M. H. Kim, M. Hirose, T. J. Moon, S. Y. Matsumoto, R. Kiuchi, T. Takahashi, Manami Nakagawa, E. Hayata, Jihwa Lee, Y. Nakada, Hitoshi Tamura, F. Schupp, Hidetaka Kobayashi, Hiroyuki Ekawa, K. Agari, Yudai Ichikawa, M. Ohashi, Kotaro Shirotori, Yoko Endo, B. Bassalleck, A. Kasagi, Satoshi Sato, R. Goto, E. Umezaki, K. Ito, Manabu Moritsu, S. Ashikaga, Yuya Akazawa, Masahiro Yoshimoto, Yoshikazu Ishikawa, K. Miwa, Hiroyuki Sako, Yuki Fujikawa, M. Ichikawa, J. Pochodzalla, S. Y. Ryu, A. T. Moe, Kenichi Imai, Hiroki Ito, Kazuya Watanabe, Takashi Yamamoto, S. H. Hwang, K. Inaba, S. Ozawa, N. Fujioka, S. H. Kim, Hitoshi Takahashi, Erina Hirose, Shoichi Hasegawa, Y. Nagase, R Honda, Seongbae Yang, K. Hicks, S. Hoshino, T. Hashimoto, J. Y. Sohn, T. Akaishi, Yuki Sato, A. N. L. Nyaw, T. Nanamura, Shunsuke Kanatsuki, Y. Toyama, Aye Moh Moh Theint, M. M. Soe, Myint Kyaw Soe, Takeshi Koike, Y Han, J. K. Ahn, Kenji Hosomi, Kensuke Kobayashi, S. Kinbara, K. Hoshino, Megumi Naruki, A. Koshikawa, K. Tanida, C. S. Yoon, Manami Fujita, D. Nakashima, K. Oue, Toyoki Watabe, W. S. Jung, Kazuma Nakazawa, Takayoshi Kawai, Y. Ogura, Mifuyu Ukai, and Kazuhiro Suzuki
- Subjects
Physics ,Binding energy ,Hyperon ,General Physics and Astronomy ,State (functional analysis) ,Coupling (probability) ,01 natural sciences ,0103 physical sciences ,Bound state ,Coulomb ,Absorption (logic) ,Atomic physics ,010306 general physics ,Energy (signal processing) - Abstract
In an emulsion-counter hybrid experiment performed at J-PARC, a Ξ^{-} absorption event was observed which decayed into twin single-Λ hypernuclei. Kinematic calculations enabled a unique identification of the reaction process as Ξ^{-}+^{14}N→_{Λ}^{10}Be+_{Λ}^{5}He. For the binding energy of the Ξ^{-} hyperon in the Ξ^{-}-^{14}N system a value of 1.27±0.21 MeV was deduced. The energy level of Ξ^{-} is likely a nuclear 1p state which indicates a weak ΞN-ΛΛ coupling.
- Published
- 2021
43. Observation of Variations in Cosmic Ray Single Count Rates During Thunderstorms and Implications for Large-Scale Electric Field Changes
- Author
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R. U. Abbasi, T. Abu-Zayyad, M. Allen, Y. Arai, R. Arimura, E. Barcikowski, J. W. Belz, D. R. Bergman, S. A. Blake, I. Buckland, R. Cady, B. G. Cheon, J. Chiba, M. Chikawa, T. Fujii, K. Fujisue, K. Fujita, R. Fujiwara, M. Fukushima, R. Fukushima, G. Furlich, N. Globus, R. Gonzalez, W. Hanlon, M. Hayashi, N. Hayashida, K. Hibino, R. Higuchi, K. Honda, N. Husseini, D. Ikeda, T. Inadomi, N. Inoue, T. Ishii, H. Ito, D. Ivanov, H. Iwakura, A. Iwasaki, H. M. Jeong, S. Jeong, H. Johnson, C. C. H. Jui, K. Kadota, F. Kakimoto, O. Kalashev, K. Kasahara, S. Kasami, H. Kawai, S. Kawakami, S. Kawana, K. Kawata, I. Kharuk, E. Kido, H. B. Kim, J. H. Kim, M. H. Kim, S. W. Kim, Y. Kimura, S. Kishigami, Y. Kubota, S. Kurisu, V. Kuzmin, M. Kuznetsov, Y. J. Kwon, K. H. Lee, R. LeVon, B. Lubsandorzhiev, J. P. Lundquist, K. Machida, H. Matsumiya, T. Matsuyama, J. N. Matthews, R. Mayta, J. Mazich, M. Minamino, K. Mukai, I. Myers, P. Myers, S. Nagataki, K. Nakai, R. Nakamura, T. Nakamura, Y. Nakamura, A. Nakazawa, E. Nishio, T. Nonaka, K. O’Brien, H. Oda, S. Ogio, M. Ohnishi, H. Ohoka, Y. Oku, T. Okuda, Y. Omura, M. Ono, R. Onogi, A. Oshima, S. Ozawa, I. H. Park, M. Potts, M. S. Pshirkov, J. Remington, D. C. Rodriguez, G. I. Rubtsov, D. Ryu, H. Sagawa, R. Sahara, Y. Saito, N. Sakaki, T. Sako, N. Sakurai, K. Sano, K. Sato, T. Seki, K. Sekino, P. D. Shah, Y. Shibasaki, F. Shibata, N. Shibata, T. Shibata, H. Shimodaira, B. K. Shin, H. S. Shin, D. Shinto, J. D. Smith, P. Sokolsky, N. Sone, B. T. Stokes, T. A. Stroman, Y. Takagi, Y. Takahashi, M. Takamura, M. Takeda, R. Takeishi, A. Taketa, M. Takita, Y. Tameda, H. Tanaka, K. Tanaka, M. Tanaka, Y. Tanoue, S. B. Thomas, G. B. Thomson, P. Tinyakov, I. Tkachev, H. Tokuno, T. Tomida, S. Troitsky, R. Tsuda, Y. Tsunesada, Y. Uchihori, S. Udo, T. Uehama, F. Urban, T. Wong, M. Yamamoto, K. Yamazaki, J. Yang, K. Yashiro, F. Yoshida, Y. Yoshioka, Y. Zhezher, and Z. Zundel
- Subjects
High Energy Astrophysical Phenomena (astro-ph.HE) ,Physics - Atmospheric and Oceanic Physics ,High Energy Physics - Experiment (hep-ex) ,Astrophysics::High Energy Astrophysical Phenomena ,Atmospheric and Oceanic Physics (physics.ao-ph) ,FOS: Physical sciences ,Astrophysics - High Energy Astrophysical Phenomena ,High Energy Physics - Experiment - Abstract
We present the first observation by the Telescope Array Surface Detector (TASD) of the effect of thunderstorms on the development of cosmic ray single count rate intensity over a 700 km$^{2}$ area. Observations of variations in the secondary low-energy cosmic ray counting rate, using the TASD, allow us to study the electric field inside thunderstorms, on a large scale, as it progresses on top of the 700 km$^{2}$ detector, without dealing with the limitation of narrow exposure in time and space using balloons and aircraft detectors. In this work, variations in the cosmic ray intensity (single count rate) using the TASD, were studied and found to be on average at the $\sim(0.5-1)\%$ and up to 2\% level. These observations were found to be both in excess and in deficit. They were also found to be correlated with lightning in addition to thunderstorms. These variations lasted for tens of minutes; their footprint on the ground ranged from 6 to 24 km in diameter and moved in the same direction as the thunderstorm. With the use of simple electric field models inside the cloud and between cloud to ground, the observed variations in the cosmic ray single count rate were recreated using CORSIKA simulations. Depending on the electric field model used and the direction of the electric field in that model, the electric field magnitude that reproduces the observed low-energy cosmic ray single count rate variations was found to be approximately between 0.2-0.4 GV. This in turn allows us to get a reasonable insight on the electric field and its effect on cosmic ray air showers inside thunderstorms.
- Published
- 2021
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- View/download PDF
44. POS0856 CLINICAL UTILITY OF BREATH-HOLDING TEST FOR MEASURING CARDIOPULMONARY FUNCTION IN PATIENTS WITH SYSTEMIC SCLEROSIS
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Eunwon Lee, J. W. Park, J. Yeo, M. H. Kim, and Joo Kyung Park
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Rheumatology ,business.industry ,Anesthesia ,Immunology ,Immunology and Allergy ,Medicine ,In patient ,Cardiopulmonary function ,business ,General Biochemistry, Genetics and Molecular Biology ,Test (assessment) - Abstract
Background:Interstitial lung disease (ILD) and pulmonary arterial hypertension (PAH) are major causes of death in systemic sclerosis (SSc). Six-minute-walk test (6MWT) is a standard outcome measure for exercise capacity in cardiopulmonary diseases. However, the results of 6MWT may not reflect real cardiopulmonary function of SSc patients in whom musculoskeletal system is frequently inflicted.Objectives:This study aimed to evaluate the clinical utility of breath-holding test (BHT) in evaluating cardiopulmonary function in SSc patients, as compared with 6MWT.Methods:Seventy-two patients with SSc were prospectively enrolled and underwent BHT and 6MWT with measurement of Borg score and Scleroderma Health Assessment Questionnaire (SHAQ). Data on diffusing capacity for carbon monoxide (DLCO, %), forced vital capacity (FVC, % and liters), and ejection fraction and pulmonary arterial systolic pressure (PASP) measured by transthoracic echocardiography (TTE), were also collected. For BHT, participants were required to make a maximum expiration followed by a maximum inspiration and to hold the breath as long as possible at maximum inspiratory level. This procedure was repeated three times, with 5-minute intervals. 6MWT was performed according to the American Thoracic Society guidelines. Pearson’s correlation test was applied to demonstrate the relationship between BHT results and each clinical parameter.Results:Among 72 (66 female) patients, mean (SD) age was 57.1 (11.1) years, modified Rodnan skin score 10.6 (10.5), SHAQ 0.64 (0.61) and 6MWT distance 473.5 (95.5) m. Mean BHT time was 35.05 (14.90) sec at the first time, 38.92 (16.14) sec at the second time, and 41.11 (17.71) sec at the third time. The BHT time showed a statistically significant negative correlation with Borg scale (pre-test, r = -0.336, p = 0.002; post-test, r = -0.252, p = 0.034; Figure 1 and Table 1), while 6MWT showed a negative correlation with only post-test Borg scale (pre-test, r = -0.113 p = 0.343; post-test, r = -0.351 p = 0.002; Table 1). The BHT time was positively correlated with DLCO (%, r = 0.409, p < 0.001) and FVC (liters, r = 0.402, p < 0.001) (Table 1). We also found a statistically significant correlation between BHT time and SHAQ score (r = -0.451, p < 0.001; Table 1). However, EF and PASP by TTE showed no significant relationship with BHT time (EF, r = -0.108, p = 0.374; PASP, r = -0.246, p = 0.054; Table 1).Table 1.Pearson’s correlation coefficients (r) for the relation between BHT and clinical parameters in comparison to 6MWT.Pre-test Borg scalePost-test Borg scaleDLCO(%)FVC(L)FVC(%)FVC/DLCOEF(%)PSAP(mm Hg)SHAQ (score)BHT (sec)-0.366**-0.252*0.409***0.402**0.191-0.244***-0.108-0.246-0.451***6MWT (m)-0.113-0.351**0.297*0.321**0.063-0.250*0.137-0.354**-0.531***BHT, breath-holding test; 6MWT, 6-minute-walk test; DLCO, diffusing capacity for carbon monoxide; FVC, forced vital capacity; EF, ejection fraction estimated by transthoracic echocardiography; SHAQ, Scleroderma Health Assessment Questionnaire.* p < 0.05, ** p < 0.01, *** p < 0.001Figure 1.Association of Borg dyspnea scale with breath-holding time.Conclusion:The BHT is a simple, safe, and less time-consuming test, reflective of pulmonary parameters and SHAQ, as compared with 6MWT. Our results suggest that the BHT might be a useful surrogate marker of cardiopulmonary capacity in SSc patients.References:[1]Villalba WO, Sampaio-Barros PD, Pereira MC, Cerqueira EM, Leme CA, Jr., Marques-Neto JF, et al. Six-minute walk test for the evaluation of pulmonary disease severity in scleroderma patients. Chest. 2007;131(1):217-22.[2]Garin MC, Highland KB, Silver RM, Strange C. Limitations to the 6-minute walk test in interstitial lung disease and pulmonary hypertension in scleroderma. J Rheumatol. 2009;36(2):330-6.[3]Barnai M, Laki I, Gyurkovits K, Angyan L, Horvath G. Relationship between breath-hold time and physical performance in patients with cystic fibrosis. Eur J Appl Physiol. 2005;95(2-3):172-8.Acknowledgements:This study would not have been possible without help from research assistant, Sung-Soon Cho.Disclosure of Interests:Jina Yeo: None declared, Mi Hyeon Kim: None declared, Jun Won Park: None declared, Jin Kyun Park: None declared, Eun Bong Lee Consultant of: Pfizer, Grant/research support from: GC Pharma and Handok Inc.
- Published
- 2021
45. Observation of Coulomb-Assisted Nuclear Bound State of Ξ^{-}-^{14}N System
- Author
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S H, Hayakawa, K, Agari, J K, Ahn, T, Akaishi, Y, Akazawa, S, Ashikaga, B, Bassalleck, S, Bleser, H, Ekawa, Y, Endo, Y, Fujikawa, N, Fujioka, M, Fujita, R, Goto, Y, Han, S, Hasegawa, T, Hashimoto, T, Hayakawa, E, Hayata, K, Hicks, E, Hirose, M, Hirose, R, Honda, K, Hoshino, S, Hoshino, K, Hosomi, S H, Hwang, Y, Ichikawa, M, Ichikawa, K, Imai, K, Inaba, Y, Ishikawa, H, Ito, K, Ito, W S, Jung, S, Kanatsuki, H, Kanauchi, A, Kasagi, T, Kawai, M H, Kim, S H, Kim, S, Kinbara, R, Kiuchi, H, Kobayashi, K, Kobayashi, T, Koike, A, Koshikawa, J Y, Lee, T L, Ma, S Y, Matsumoto, M, Minakawa, K, Miwa, A T, Moe, T J, Moon, M, Moritsu, Y, Nagase, Y, Nakada, M, Nakagawa, D, Nakashima, K, Nakazawa, T, Nanamura, M, Naruki, A N L, Nyaw, Y, Ogura, M, Ohashi, K, Oue, S, Ozawa, J, Pochodzalla, S Y, Ryu, H, Sako, S, Sato, Y, Sato, F, Schupp, K, Shirotori, M M, Soe, M K, Soe, J Y, Sohn, H, Sugimura, K N, Suzuki, H, Takahashi, T, Takahashi, T, Takeda, H, Tamura, K, Tanida, A M M, Theint, K T, Tint, Y, Toyama, M, Ukai, E, Umezaki, T, Watabe, K, Watanabe, T O, Yamamoto, S B, Yang, C S, Yoon, J, Yoshida, M, Yoshimoto, D H, Zhang, and Z, Zhang
- Abstract
In an emulsion-counter hybrid experiment performed at J-PARC, a Ξ^{-} absorption event was observed which decayed into twin single-Λ hypernuclei. Kinematic calculations enabled a unique identification of the reaction process as Ξ^{-}+^{14}N→_{Λ}^{10}Be+_{Λ}^{5}He. For the binding energy of the Ξ^{-} hyperon in the Ξ^{-}-^{14}N system a value of 1.27±0.21 MeV was deduced. The energy level of Ξ^{-} is likely a nuclear 1p state which indicates a weak ΞN-ΛΛ coupling.
- Published
- 2020
46. Transverse Single-Spin Asymmetry for Very Forward Neutral Pion Production in Polarized p+p Collisions at s=510 GeV
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Takashi Sako, Yoshitaka Itow, Jongmin Lee, M. H. Kim, T. Ljubicic, N. Sakurai, R. Seidl, O. Adriani, K. Sato, Y. Makino, Eugenio Berti, Hiroaki Menjo, Raffaello D'Alessandro, I. Nakagawa, A. Ogawa, K. Tanida, Shoji Torii, Y. Goto, Lorenzo Bonechi, Q. D. Zhou, M. Ueno, K. Kasahara, J. S. Park, Alessia Tricomi, and Byung-Sik Hong
- Subjects
Physics ,media_common.quotation_subject ,General Physics and Astronomy ,Asymmetry ,Momentum ,Nuclear physics ,Transverse plane ,Pion ,Pseudorapidity ,High Energy Physics::Experiment ,Nuclear Experiment ,Relativistic Heavy Ion Collider ,STAR detector ,media_common ,Spin-½ - Abstract
Transverse single-spin asymmetries of very forward neutral pions generated in polarized p+p collisions allow us to understand the production mechanism in terms of perturbative and nonperturbative strong interactions. During 2017, the RHICf Collaboration installed an electromagnetic calorimeter in the zero-degree region of the STAR detector at the Relativistic Heavy Ion Collider (RHIC) and measured neutral pions produced at pseudorapidity larger than 6 in polarized p+p collisions at sqrt[s]=510 GeV. The large nonzero asymmetries increasing both in longitudinal momentum fraction x_{F} and transverse momentum p_{T} have been observed at low transverse momentum p_{T}
- Published
- 2020
47. Treatment outcome and risk factors associated with diffuse axonal injury in patients with moderate to severe head injury
- Author
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Suk-Kyung Hong, Sang Ryong Jeon, M. H. Kim, Seungjoo Lee, and Sung Woo Roh
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medicine.medical_specialty ,Univariate analysis ,Subarachnoid hemorrhage ,business.industry ,Traumatic brain injury ,Diffuse axonal injury ,Head injury ,Diffuse Axonal Injury ,Revised Trauma Score ,medicine.disease ,Magnetic Resonance Imaging ,Treatment Outcome ,Hematoma ,Risk Factors ,Internal medicine ,medicine ,Craniocerebral Trauma ,Humans ,Surgery ,Neurology (clinical) ,Stage (cooking) ,business - Abstract
Aim Diffuse axonal injury (DAI) is an important determining factor of morbidity and mortality after traumatic brain injury (TBI). However, its clinical outcome remains a subject of debate. Material and methods A total of 992 TBI patients visited our hospital between 2011 and 2016. Thirty-seven patients diagnosed with DAI were enrolled in this study and stratified by DAI stage: stage I, 20 patients (54.1%); stage II, 4 patients (10.8%); and stage III, 13 patients (35.1%). Results The mean age and the median follow-up period were 45.43 years and 13 months, respectively. Patient demographic data and clinical findings on admission showed no differences according to DAI stage, except for the revised trauma score (RTS) (p = 0.026). In univariate analysis, stages I and II vs. III (p = 0.001) and stages I vs. II and III (p = 0.019), transfusion within 24 hours of visit (p = 0.033), shock or cardiac arrest (p = 0.006), traumatic subarachnoid hemorrhage (T-SAH) (p = 0.011), and subdural hematoma (SDH) (p = 0.009) were significantly correlated with Glasgow outcome score (GOS). In multivariate analysis, DAI stage I and II vs. III (p = 0.005) and SDH (p = 0.040) were significant. Conclusion Clinically, stage II was more correlated with stage I, rather than stage III. Stage III showed a much poorer outcome compared to stages I and II. Magnetic resonance imaging (MRI) should be promptly performed in all TBI patients when a patient's level of consciousness and cranial computed tomography (CT) does not match, as there is a possibility of stage III DAI.
- Published
- 2020
48. Early (≤48 Hours) versus Late (>48 Hours) Surgery in Spinal Cord Injury: Treatment Outcomes and Risk Factors for Spinal Cord Injury
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Suk-Kyung Hong, M. H. Kim, Sang Ryong Jeon, Sung Woo Roh, and Seungjoo Lee
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Adult ,Male ,medicine.medical_specialty ,Time Factors ,Adolescent ,Treatment outcome ,Thoracic Vertebrae ,Time-to-Treatment ,Cohort Studies ,Young Adult ,03 medical and health sciences ,Early surgery ,0302 clinical medicine ,Spine surgery ,Risk Factors ,Humans ,Medicine ,Spinal cord injury ,Spinal Cord Injuries ,Aged ,Retrospective Studies ,Aged, 80 and over ,030222 orthopedics ,Lumbar Vertebrae ,business.industry ,Significant difference ,American Spinal Injury Association ,Retrospective cohort study ,Guideline ,Middle Aged ,Decompression, Surgical ,medicine.disease ,Surgery ,Treatment Outcome ,Cervical Vertebrae ,Female ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
Objectives Surgical management of spinal cord injury (SCI) is challenging. There is no standard guideline regarding the timing of surgery, although physicians have prioritized early surgery over the past decades. Although better outcomes have been observed from these studies, the definition of early surgery has been controversial, although mostly limited to 24-hours after injury. For some hospitals, this early surgery could be difficult to implement in practice. Hence, we re-evaluated the timing of early surgery as surgery within 48 hours and investigated the surgical outcomes of SCI depending on whether surgery was performed early (≤48 hours) or late (>48 hours). The primary outcomes were improvement in the American Spinal Injury Association Impairment Scale (AIS) grade in early and late surgery groups. Methods This study was a retrospective cohort study in individuals aged 15–85 years, who underwent surgery for SCI between 2005 and 2016. The rate of AIS grade improvements was measured at 6 months after injury. Of the 86 enrolled patients, 31 (mean, 40.9 ± 12.64 hours) and 55 (mean, 168.25 ± 93.01 hours) patients were assigned to the early and late surgery groups, respectively. Results AIS grade improvement was significantly greater in the early than in the late group (P = 0.039). In the early group, there was no significant difference in neurologic improvements among the AIS B, C, and D groups, but the AIS A group showed a significant improvement (P = 0.015). This finding was not observed in the late group (P = 0.060). AIS grade improvement was also significantly greater in the incomplete SCI group than in the complete SCI group, for all measurements (early, P = 0.007, late, P = 0.009). Other factors that significantly affected clinical outcomes were AIS grade on admission and the level of the injury.
- Published
- 2018
49. CU03-1001, 50% ethanol-extract of Moutan radices cortex and Cinnamomi ramulus (1:1) inhibited laser-induced choroidal neovascularization (CNV) in Brown Norway rats
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Y-G Kwon, C-S Kim, K Jo, Ji-Yul Kim, Jinmoo Kim, S-H Jung, M-H Kim, S-W Hyun, and IS Lee
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chemistry.chemical_compound ,medicine.anatomical_structure ,Ethanol ,Choroidal neovascularization ,chemistry ,Cortex (anatomy) ,medicine ,BROWN NORWAY ,Pharmacology ,medicine.symptom - Published
- 2019
50. Correlation between Crossed Cerebellar Diaschisis and Prognosis of Functional Ambulation in Subacute Stroke Patients
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N. R. Yun, J. H. Kim, S. A. Park, Y. H. Lim, M. C. Joo, and M. H. Kim
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Crossed cerebellar diaschisis ,medicine.medical_specialty ,business.industry ,Internal medicine ,Subacute stroke ,medicine ,Cardiology ,business ,medicine.disease ,Stroke - Published
- 2018
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