753 results on '"M. A., Almutairi"'
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2. Bangladesh,Saudi Arabia : Ambassador of the Kingdom of Saudi Arabia His Excellency Mr. Abdullah M. H. Almutairi paid a courtesy call on the Honble State Minister for Foreign Affairs Mr. Md. Shahriar Alam
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Ambassadors ,Cabinet officials ,Business, international - Abstract
Ambassador of the Kingdom of Saudi Arabia His Excellency Mr. Abdullah M. H. Almutairi paid a courtesy call on the Honble State Minister for Foreign Affairs Mr. Md. Shahriar Alam, [...]
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- 2017
3. SUSTAINABILITY OF SUPPLY CHAIN UNILEVER CASE STUDY
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Yousef M H Almutairi
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- 2023
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4. Effect of substrate temperature and precursor salt molarities on the nickel oxide physical properties
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F. M. M. Almutairi, N. Al-Khalli, N. B. Arkook, N. M. K. Sebhi, and M. S. Aida
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Atomic and Molecular Physics, and Optics - Published
- 2022
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5. An Efficient Signal Processing Algorithm for Detecting Abnormalities in EEG Signal Using CNN
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Thalakola Syamsundararao, A. Selvarani, R. Rathi, N. Vini Antony Grace, D. Selvaraj, Khalid M. A. Almutairi, Wadi B. Alonazi, K. S. A. Priyan, and Ramata Mosissa
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Epilepsy ,Article Subject ,Seizures ,Humans ,Electroencephalography ,Signal Processing, Computer-Assisted ,Radiology, Nuclear Medicine and imaging ,Algorithms - Abstract
Electroencephalography (EEG) is crucial for epilepsy detection; however, detecting abnormalities takes experience and knowledge. The electroencephalogram (EEG) is a technology that measures brain motion and represents the brain’s function. EEG is an effective instrument for deciphering the brain’s complicated activity. The information contained in the EEG signal pertains to the electric functioning of the brain. Neurologists have typically used direct visual inspection to detect epileptogenic abnormalities. This method is time-consuming, restricted by technical artifacts, produces varying findings depending on the reader’s level of experience, and is ineffective at detecting irregularities. As a result, developing automated algorithms for detecting anomalies in EEGs associated with epilepsy is critical. The construction of a novel class of convolutional neural networks (CNNs) for detecting aberrant waveforms and sensors in epilepsy EEGs is described in this research. In this study, EEG signals are analyzed using a convolutional neural network (CNN). For the automatic detection of abnormal and normal EEG indications, a novel deep one-dimensional convolutional neural network (1D CNN) model is suggested in this paper. The regular, pre-ictal, and seizure categories are detected using this approach. The proposed model achieves an accuracy of 85.48% and a reduced categorization error rate of 14.5%.
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- 2022
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6. The Prevalence of Depression among Medical Students: A Worldwide Literature Review
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Abdullah J. A. Alomran, Fawaz Majed Ata'Allah Sh Salman, Abboud Mohammad Alhussain, Salman S. S. S. S. A. Alazemi, Mohammad R. M. R. H. Alajmi, Bandar B. J. M. M. Almutairi, and Abdulaziz H. M. M. M. Alajmi
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education - Abstract
Stress is one of the main factors that might lead to depression in the long term; medical students are susceptible to stress and depression more than other students. Aim: to look at the prevalence of depression among medical students. Methodology: The authors looked at published studies on the internet about the depression rates among medical students in different areas around the world. Results: Most of the literature showed that there is a significant prevalence of depression among students during medical school. Conclusion: Due to high rates of depression among medical students, coping strategies for stress and depression should be offered to medical students to prevent future complications.
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- 2021
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7. The underrepresentation of females in antihypertensive medication over the years: a scoping review
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Z Mohseni-Alsalhi, M A M Vesseur, S A J S Laven, E W P Vaes, N Wilmes, D A M Meijs, E M Van Luik, C J R Dikovec, J Wiesenberg, M F Almutairi, E B N J Janssen, S De Haas, M E A Spaanderman, and C Ghossein-Doha
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Cardiology and Cardiovascular Medicine - Abstract
Background Hypertension is one of the leading global risk factors for cardiovascular disease-related morbidity and mortality. Females have historically been underrepresented in clinical trials resulting in presumed sex-related disparities in antihypertensive treatment effects. The past decade, widespread attention has been paid to this shortcoming aiming at increasing females' representation in clinical trials. Purpose To investigate whether in studies investigating the effect of antihypertensive drugs 1) the representation of females and 2) presentation of sex-stratified data has increased over the past decades. Methods We performed a scoping review after systematically searching PubMed and Embase for studies evaluating the effects of the five major groups of antihypertensive medication from inception (1945) until May 2020. The review was registered in Prospero database. Studies were only included if they 1) investigated one class of the five main groups of antihypertensive medications (beta-blockers, angiotensin converting enzyme inhibitors, angiotensin receptor blockers, calcium channel blockers, and diuretics, 2) human studies, 3) investigated adults ≥18 years of age, 4) were written in English or Dutch. We excluded articles if 1) only abstract was available and full report was not found, 2) unsuitable study design, 3) no reference group included, 4) outcome not related to cardiovascular health, 5) no registration of specific dose and duration information. The primary outcome was the proportion of included females over time, stratified per decade. The secondary outcome was whether sex-stratification was reported. Linear regression analysis with beta coefficient (β) and 95% CI was performed to explore the associations between the percentage of females included in the studies over time. Results The search strategy resulted in 73,867 potential articles. After study selection based on title/abstract and full text, 2,079 original studies were eligible for our study. These included 1,395,264 adults of which the mean percentage of females participating in all included studies was 27.9% (Figure 1, Table 1). The percentage of females participating in antihypertensive studies showed a slight increase each year by 0.4% (95% CI 0.36–0.53, P Conclusion Despite yearly increase in female participation in antihypertensive studies, females still only account for only one third of the study population. Moreover, less than 10% of studies report sex stratified data. Considering the global burden of hypertension, more differentiated sex-specific attention remains critically needed. Funding Acknowledgement Type of funding sources: None.
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- 2022
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8. Nature of Enhanced Brønsted Acidity Induced by Extraframework Aluminum in an Ultrastabilized Faujasite Zeolite: An In Situ NMR Study
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Emiel J. M. Hensen, Brahim Mezari, Pieter C. M. M. Magusin, Sami M. T. Almutairi, Evgeny A. Pidko, Inorganic Materials & Catalysis, and EIRES Chem. for Sustainable Energy Systems
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In situ ,chemistry.chemical_element ,02 engineering and technology ,engineering.material ,010402 general chemistry ,01 natural sciences ,Medicinal chemistry ,Article ,Coatings and Films ,chemistry.chemical_compound ,Energy(all) ,Aluminium ,Electronic ,Journal Article ,Optical and Magnetic Materials ,Physical and Theoretical Chemistry ,Zeolite ,Benzene ,Faujasite ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Surfaces ,General Energy ,Deuterium ,chemistry ,engineering ,Sodalite ,0210 nano-technology ,Brønsted–Lowry acid–base theory - Abstract
The enhancing effect of extraframework Al (EFAl) species on the acidity of bridging hydroxyl groups in a steam-calcined faujasite zeolite (ultrastabilized Y, USY) was investigated by in situ monitoring the H/D exchange reaction between benzene and deuterated zeolites by 1H MAS NMR spectroscopy. This exchange reaction involves Brønsted acid sites (BAS) located in sodalite cages and supercages. In a reference faujasite zeolite free from EFAl, both populations of BAS are equally and relatively slowly reactive toward C6H6. In USY, in stark contrast, the H/D exchange of sodalite hydroxyl groups is significantly faster than that of hydroxyl groups located in the faujasite supercages, even though benzene has only access to the supercages. This evidences selective enhancement of BAS near Lewis acidic EFAl species, which according to the NMR findings are located in the faujasite sodalite cages.
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- 2021
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9. MRI Evaluation of Acute Abdominal and Pelvic Pain in Pregnant Patients
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Amira A. A. Abuteir, Maha M. H. Almutairi, Sharifa M. Hadi, and Rufida E. Ahmed
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medicine.medical_specialty ,business.industry ,Pelvic pain ,medicine ,General Medicine ,Radiology ,medicine.symptom ,business - Published
- 2021
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10. Stigmatization and discrimination against people living with HIV/AIDS: Knowledge, attitudes, and practices of healthcare workers in the primary healthcare centers in Madinah, Saudi Arabia, 2022
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Hani H O, Alharbi, Sami A R, Al-Dubai, Rami M H, Almutairi, and Mohammed H, Alharbi
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There are very few studies in Saudi Arabia on stigmatization and discrimination against people living with HIV/AIDS (PLWHA), a critical step for the prevention and control of HIV. The aim of this study was to assess the level of stigmatization and discrimination against PLWHA by healthcare workers (HCWs) as well as their knowledge, attitude, and practices (KAP).This cross-sectional study included 182 HCWs at primary healthcare centers in Medina, Saudi Arabia. The validated short version of the Healthcare Provider HIV/AIDS Stigma Scale and the AIDS Attitude Scale were used in this research. Student'sMost participants were males (58.2%) and aged more than 30 years (60.4%). The tendency to stigmatizing behavior was present in 24.2%-68.17% of the participants, and discriminatory practice was present in 11.5%-50% of the participants. In multiple linear regression analysis, factors that independently predicted the knowledge score were being a doctor compared to nurses (This study found that stigmatization and discrimination were less prevalent in HCWs who had good HIV-related knowledge and had received in-service training for PLWHA. The results highlight the significance of continuing education and training opportunities for HCWs to provide effective and appropriate treatment to PLWHA.
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- 2022
11. Dense Convolutional Neural Network for Detection of Cancer from CT Images
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S. V. N. Sreenivasu, S. Gomathi, M. Jogendra Kumar, Lavanya Prathap, Abhishek Madduri, Khalid M. A. Almutairi, Wadi B. Alonazi, D. Kali, and S. Arockia Jayadhas
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ComputingMethodologies_PATTERNRECOGNITION ,Article Subject ,General Immunology and Microbiology ,Neoplasms ,Image Processing, Computer-Assisted ,Humans ,Reproducibility of Results ,General Medicine ,Neural Networks, Computer ,Tomography, X-Ray Computed ,General Biochemistry, Genetics and Molecular Biology - Abstract
In this paper, we develop a detection module with strong training testing to develop a dense convolutional neural network model. The model is designed in such a way that it is trained with necessary features for optimal modelling of the cancer detection. The method involves preprocessing of computerized tomography (CT) images for optimal classification at the testing stages. A 10-fold cross-validation is conducted to test the reliability of the model for cancer detection. The experimental validation is conducted in python to validate the effectiveness of the model. The result shows that the model offers robust detection of cancer instances that novel approaches on large image datasets. The simulation result shows that the proposed method provides analyzes with 94% accuracy than other methods. Also, it helps to reduce the detection errors while classifying the cancer instances than other methods the several existing methods.
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- 2022
12. Impact of ANN in Revealing of Viral Peptides
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M. Rajkumar, Shankar Nayak Bhukya, N. Ahalya, G. Elumalai, K. Sivanandam, Khalid M. A. Almutairi, Wadi B. Alonazi, S. R. Soma, and Markos Makiso Urugo
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Antifungal Agents ,General Immunology and Microbiology ,Article Subject ,Computer Simulation ,Neural Networks, Computer ,General Medicine ,Peptides ,Algorithms ,General Biochemistry, Genetics and Molecular Biology - Abstract
All organisms contain antimicrobial peptides (AMPs), which are a critical component of the innate immune system. These chemicals have the ability to suppress the growth of a variety of fungi, bacteria, and viruses. Because AMPs interact with structural components of the microbial cell membrane and have a wide range of cellular targets, bacteria are unlikely to be able to develop resistance to them in the short term. The underlying structure of AMPs is critical in determining the selectivity with which they target their respective targets. As far as we know, peptides have not been tested in a lab to see if they can fight bacteria, fungus, and viruses in real life. In this paper, we develop an artificial neural network (ANN) using a back propagation neural network (BPNN) that enables optimal classification of tendency of a peptide sequence that involves the activities of antifungal, antibacterial, or antiviral. The BPNN is trained on the datasets collected across different repositories and then the overfitting is avoided using particle swarm optimization (PSO) algorithm. Hence, at the time of testing, the BPNN clearly finds the predicted samples belonging to the same classes and this avoids the problem of finding the false positives. The simulation is conducted to test the efficacy of the model against various metrics that includes accuracy, precision, recall, and f1-measure. The effectiveness of the BPNN-PSO model in classifying instances at a faster rate than other techniques is demonstrated by its performance. The principle is straightforward, it is not difficult to programme, it converges more quickly, and it generally offers a superior solution.
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- 2022
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13. An Artificial Intelligence-Based Bio-Medical Stroke Prediction and Analytical System Using a Machine Learning Approach
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R. Pitchai, Bhasker Dappuri, P. V. Pramila, M. Vidhyalakshmi, S. Shanthi, Wadi B. Alonazi, Khalid M. A. Almutairi, R. S. Sundaram, and Ibsa Beyene
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Machine Learning ,Stroke ,Support Vector Machine ,General Computer Science ,Article Subject ,Artificial Intelligence ,General Mathematics ,General Neuroscience ,Humans ,General Medicine ,Algorithms - Abstract
Stroke-related disabilities can have a major negative effect on the economic well-being of the person. When left untreated, a stroke can be fatal. According to the findings of this study, people who have had strokes generally have abnormal biosignals. Patients will be able to obtain prompt therapy in this manner if they are carefully monitored; their biosignals will be precisely assessed and real-time analysis will be performed. On the contrary, most stroke diagnosis and prediction systems rely on image analysis technologies such as CT or MRI, which are not only expensive but also hard to use. In this study, we develop a machine learning algorithm for the prediction of stroke in the brain, and this prediction is carried out from the real-time samples of electromyography (EMG) data. The study uses synthetic samples for training the support vector machine (SVM) classifier and then the testing is conducted in real-time samples. To improve the accuracy of prediction, the samples are generated using the data augmentation principle, which supports training with vast data. The simulation is conducted to test the efficacy of the model, and the results show that the proposed classifier achieves a higher rate of classification accuracy than the existing methods. Furthermore, it is seen that the rate of precision, recall, and f-measure is higher in the proposed SVM than in other methods.
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- 2022
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14. Deep Neural Networks for Optimal Selection of Features Related to Flu
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B. Tarakeswara Rao, V.N. Lakshmana Kumar, D. Padmapriya, Kumud Pant, Tejaswini B, Wadi B. Alonazi, Khalid M. A. Almutairi, null D.Raj, and null Ramesh Shahabadkar
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Complementary and alternative medicine ,Article Subject - Abstract
In recent times, humans who have been exposed to influenza A viruses (IAV) may not become hostile. Despite the fact that KLRD1 has been discovered as an influenza susceptibility biomarker, it remains to be seen if pre-exposure host gene expression can predict flu symptoms. In this paper, we enable the examination of flu using deep neural networks from input human gene expression datasets with various subtype viruses. This study enables the utilization of these datasets to forecast the spread of flu and can provide the necessary steps to eradicate the flu. The simulation is conducted to test the efficiency of the model in predicting the spread against various input datasets. The results of the simulation show that the proposed method offers a better prediction ability of 2.98% more than other existing methods in finding the spread of flu.
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- 2022
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15. Conceptual artificial intelligence framework to improving English as second language
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Alexander Gegov, Farzad Arabikhan, Aminah F. D. M. F. Almutairi, and Mo Adda
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education ,05 social sciences ,language-learning ,050301 education ,styling ,02 engineering and technology ,Language acquisition ,artificial intelligence ,intelligent tutoring systems ,English as Second Language ,Engineering education ,0202 electrical engineering, electronic engineering, information engineering ,Mathematics education ,020201 artificial intelligence & image processing ,Psychology ,0503 education - Abstract
English has become a global language in modern day world. It is widely spoken among the non-native English communities as well. However, due to the lack of resources, such as, teaching literature and skilled English teachers, the teaching of English language becomes inefficient. Educational institutions and non-native English students are equally affected by these problems. In order to efficiently cope with the aforementioned issues, we propose an AI-based English learning framework. The proposed AI-based framework combines the previously proposed algorithms and other newly developed techniques to enhance the language learning. The proposed framework enables the individual learners to interact with the framework for improving and enhancing the process of learning English language. In addition, the proposed system has the capability to effectively cope with the lack of resources available to the educational institutes providing English learning courses. In addition, we also perform data collection and develop new modules that are integrated in the proposed framework. We assess the proposed framework by allowing a group of participants to learn English language. These participants are non-native speakers from a foreign land. The results make it evident, that the proposed framework assists the students in learning English as a foreign language.
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- 2020
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16. MRI Evaluation of Acute Abdominal and Pelvic Pain in Pregnant Patients
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M. Hadi, Sharifa, primary, M. H. Almutairi, Maha, additional, A. A. Abuteir, Amira, additional, and E. Ahmed, Rufida, additional
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- 2021
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17. Iron Pathophysiology in Stroke
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Mohammed M A, Almutairi, Grace, Xu, and Honglian, Shi
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Stroke ,Oxidative Stress ,Hepcidins ,Iron ,Humans - Abstract
Ischemic and hemorrhagic stroke are the common types of stroke that lead to brain injury neurological deficits and mortality. All forms of stroke remain a serious health issue, and there is little successful development of drugs for treating stroke. Incomplete understanding of stroke pathophysiology is considered the main barrier that limits this research progress. Besides mitochondria and free radical-producing enzymes, labile iron is an important contributor to oxidative stress. Although iron regulation and metabolism in cerebral stroke are not fully understood, much progress has been achieved in recent years. For example, hepcidin has recently been recognized as the principal regulator of systemic iron homeostasis and a bridge between inflammation and iron regulation. This review discusses recent research progress in iron pathophysiology following cerebral stroke, focusing molecular regulation of iron metabolism and potential treatment targets.
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- 2019
18. Crystal structure of 4-(dimethylamino)-1-(prop-2-yn-1-yl)pyridin-1-ium perchlorate, C10H13ClN2O4
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Mouslim Messali, Mohamed Reda Aouad, M. Saud Almutairi, Nadjet Rezki, and Ismail Warad
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Crystallography ,Crystal structure ,010402 general chemistry ,010403 inorganic & nuclear chemistry ,Condensed Matter Physics ,01 natural sciences ,Medicinal chemistry ,0104 chemical sciences ,Inorganic Chemistry ,Perchlorate ,chemistry.chemical_compound ,chemistry ,QD901-999 ,General Materials Science - Abstract
C10H13ClN2O4, orthorhombic, Pnma, a = 14.903(2) Å, b = 9.1004(15) Å, c = 8.7560(14) Å, V = 1187.5(3) Å3, Z = 4, Rint = 0.036, R gt(F) = 0.0284, wRref (F2 ) = 0.0795, T = 296 K.
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- 2018
19. Influence of Extraframework Aluminum on the Brønsted Acidity and Catalytic Reactivity of Faujasite Zeolite
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Pieter C. M. M. Magusin, Marcello Stefano Rigutto, Sami M. T. Almutairi, Evgeny A. Pidko, Georgy A. Filonenko, Emiel J. M. Hensen, Brahim Mezari, and Inorganic Materials & Catalysis
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Ion exchange ,Chemistry ,Organic Chemistry ,Inorganic chemistry ,Infrared spectroscopy ,Faujasite ,engineering.material ,Catalysis ,Inorganic Chemistry ,Adsorption ,engineering ,Reactivity (chemistry) ,Physical and Theoretical Chemistry ,Zeolite ,Brønsted–Lowry acid–base theory - Abstract
A series of faujasite zeolites was modified by extraframework Al (AlEF) with the goal to investigate the influence of such species on the intrinsic Brønsted acidity and catalytic activity towards paraffin cracking. The chemical state of AlEF and zeolite acidity were investigated by 27Al MAS NMR and COads IR spectroscopy, H/D exchange reaction, and propane cracking. Strongly acidic defect-free Y zeolites were obtained by substitution of framework Al by Si with (NH4)2SiF6. In accordance with the next-nearest-neighbor model, the intrinsic acidity of the protons increased with decreasing framework Al density. This increased acidity was evidenced by an increased shift of the OH stretching vibration upon CO adsorption in COads IR spectroscopy and by an increased H/D exchange rate in H/D exchange reactions with perdeuterobenzene. All of the acid sites in these zeolites were of equal strength beyond a certain Si/Al ratio. The increased acidity resulted in an enhanced propane cracking activity. Modification of a model dealuminated Y zeolite by AlEF only resulted in a small fraction of cationic AlEF species, because it was difficult to control the ion exchange process. In comparison, commercial ultrastabilized Y zeolites contained less AlEF and these species were predominantly present in cationic form. The rate of propane cracking strongly correlated to the concentration of Brønsted acid sites perturbed by cationic AlEF species. The results of MQMAS 27Al NMR spectroscopy confirmed the presence of sites perturbed by AlEF and unaffected framework Al sites. Zeolites with higher intrinsic cracking activities contained a higher proportion of perturbed sites. Although COads IR and H/D exchange methods proved to be suitable methods to probe the acidity of Y zeolites free from AlEF, they were less suitable to predict the reactivity if the Brønsted acid sites were affected by cationic AlEF species.
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- 2013
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20. Triangle of Safety Technique: A New Approach to Laparoscopic Cholecystectomy
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Abdulrahman F. M. S. Almutairi and Yousef A. M. S. Hussain
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Adult ,Male ,medicine.medical_specialty ,Adolescent ,medicine.medical_treatment ,lcsh:Surgery ,Gallbladder Diseases ,Dissection (medical) ,Cystic artery ,Cohort Studies ,Young Adult ,medicine.artery ,Electrocoagulation ,medicine ,Humans ,lcsh:RC799-869 ,Laparoscopic cholecystectomy ,Aged ,Retrospective Studies ,Hepatology ,Common bile duct ,Methodology Report ,business.industry ,Dissection ,lcsh:RD1-811 ,Middle Aged ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Cholecystectomy, Laparoscopic ,Cystic duct ,lcsh:Diseases of the digestive system. Gastroenterology ,Female ,Cholecystectomy ,Bile Ducts ,Peritoneum ,business ,Gallbladder wall ,Artery - Abstract
Backgrounds and Study Aims. Common bile duct (CBD) injury is one of the most serious complications of laparoscopic cholecystectomy (LC). Misidentification of the CBD during dissection of the Calot's triangle can lead to such injuries. The aim of the authors in this study is to present a new safe triangle of dissection. Patients and Method. 501 patients under went LC in the following approach; The cystic artery is identified and mobilized from the gall bladder (GB) medial wall down towards the cystic duct which would simultaneously divide the medial GB peritoneal attachment. This is then followed by dividing the lateral peritoneal attachment. The GB will be unfolded and the borders of the triangle of safety (TST) are achieved: cystic artery medially, cystic duct laterally and the gallbladder wall superiorly. The floor of the triangle is then divided to delineate both cystic duct and artery in an area relatively far from CBD. Results. There were little significant immediate or delayed complications. The mean operating time was 68 minutes, nearly equivalent to the conventional method. Conclusions. Dissection at TST appears to be a safe procedure which clearly demonstrates the cystic duct and may help to reduce the CBD injuries.
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- 2009
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21. STRATEGIC MANAGEMENT ROLE IN BOOSTING HOTEL PERFORMANCE.
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N., Kaliappen, C. L., Suan, S. S., Almutairi, and M. A., Almutairi
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STRATEGIC planning ,MARKET orientation ,COMPETITOR orientation ,MIDDLE managers ,ORGANIZATIONAL performance - Abstract
Copyright of Polish Journal of Management Studies is the property of Czestochowa University of Technology, Faculty of Management and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2019
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22. Evaluation of a Low-threshold Exercise And Protein supplementation intervention for Women (LEAP-W) experiencing homelessness and addiction: Protocol for a single-arm mixed methods feasibility study.
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Kennedy, Fiona, Murray, Deirdre, Ní Cheallaigh, Clíona, Romero-Ortuno, Roman, and Broderick, Julie
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PHYSICAL mobility ,EVIDENCE gaps ,HOMELESS persons ,EXERCISE therapy ,FRAILTY ,FRAIL elderly - Abstract
Background: Frailty is a complex multi-dimensional state of increased vulnerability to adverse outcomes and is associated with older age but there is growing evidence of accelerated ageing and frailty in non-geriatric populations, including those experiencing socio-economic deprivation and extreme social exclusion, such as people experiencing homelessness. Addiction, as a coping mechanism for prior trauma, is common among people who are homeless and can have a gendered dimension. Women experiencing homelessness and addiction have unique needs which require a gendered approach. The aim of this study is to evaluate the feasibility and impact of an exercise intervention to target the known physical functioning deficits and frailty which this population experiences. Methods: This quantitatively driven, sequential single-arm mixed-methods feasibility study will evaluate the feasibility and impact of a low threshold trauma informed exercise intervention on physical functioning and frailty in women experiencing homelessness and addiction. Physical function (10m Walk Test, 2Min Walk Test, Single Leg Stance, Chair Stand Test, hand grip dynamometry), frailty (Clinical Frailty Scale and the SHARE-Frailty Instrument) and nutritional status (Mini-Nutritional Status), pain (Numerical Rating Scale) and quality of life (SF 12-V2) will be evaluated. The 10-week intervention will involve a 3-times weekly exercise programme with protein supplementation. Following this, qualitative interviews, which will be thematically analysed using Braun & Clarke methodology, will be conducted. This study will be conducted in Dublin from February to July 2024. Discussion: Little is known about frailty-focussed interventions in women experiencing homelessness and addiction. This proposed study will help to increase the knowledge base regarding the physical health burden and frailty experienced by this vulnerable population and will deliver a targeted intervention with a gendered dimension to mitigate its affects. The findings of this research will help narrow the research gap and will guide clinicians and policy makers to implement unique gender-based treatment strategies for this population. (300). Clinical trials.gov number: NCT05700305. [ABSTRACT FROM AUTHOR]
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- 2025
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23. Dual Therapeutic Potential of Bioengineered Ag-doped HAp Nanocomposites Against Proteus mirabilis and MCF-7 Breast Cancer Cell Line.
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Selvam, Suvetha, Devasagayam, Alycia, and Mani, Arun Kumar
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Globally, the major threat is the rise of antimicrobial-resistant diseases and the increasing incidence of cancer, both of which are leading causes of death due to a lack of effective therapies. Nanocomposites (NCs) have recently emerged as an alternative therapeutic agent for the development of novel medications. The current study demonstrates the fast production of Ag-HAp NCs with an aqueous bark extract of Acacia nilotica and evaluates their antiquorum sensing and anticancer activities. UV-vis spectroscopy, Fourier-transformed infrared spectroscopy, X-ray diffraction analysis, zeta sizer, field emission scanning electron microscopy, and high-resolution transmission electron microscopy were used to evaluate the physicochemical and morphological observations of Ag-HAp NCs. The biofabricated NCs demonstrated the ability to inhibit the violacein production in bioreporter strain Chromobacterium violaceum and mitigate the virulent factors in multidrug-resistant Proteus mirabilis. Sub-MIC concentrations of 2% Ag-HAp NCs (80 µg/mL) efficiently decreased the quorum sensing regulated virulence factors such as biofilm formation, exopolysaccharide synthesis, urease, hemolysin, and cell motility, that contribute to antibiotic resistance. Furthermore, an invitro cytotoxicity study of 2% Ag-HAp NCs revealed exceptional anticancer potential against the MCF-7 cell line using MTT assay. The microscopic studies (ROS and DAPI assay) demonstrated that the synthesized NCs elicit cellular cytotoxicity at a low dosage (IC
50 − 23.2 µg/mL). All experiments were carried out in triplicate (n = 3) to establish the statistical significance. Thus, phyto-mediated synthesized 2% Ag-HAp NCs are environmentally acceptable and non-toxic nanomaterials suitable for biomedical applications. [ABSTRACT FROM AUTHOR]- Published
- 2025
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24. Phytocompounds from Phyllanthus acidus (L.) Skeels in the management of Monkeypox Virus infections.
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Datta, Sutapa, Sarkar, Indrani, Goswami, Nabajyoti, Mahanta, Saurov, Borah, Probodh, and Sen, Arnab
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- 2025
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25. Foliar feeding of citric acid mitigates artificial urine and NaCl-induced saline stress in hydroponic sugar beets.
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Iqbal, Muhammad Aamir, Tarikuzzaman, Mohammad, Atique, Muhammad Saad, Tulona, Zannatul Ferdous, and Lynam, Joan G.
- Abstract
In lunar and deep-space farming, saline stress (SS) induced by human urine in hydroponically grown vegetables constitutes one of the prime concerns in its utilization for plant nutrition. Therefore, an indoor hydroponic trial was performed to assess the effectiveness of foliar feeding of citric acid (CA, 50 µM as two sprays at 26 days and 38 days after germination using a common hand-held sprayer) and the control treatment (a standardized plant nutrient with 10% synthetic urine replacement and 50 mM NaCl-induced SS) for sugar beets. The response variables included vegetative growth traits of sugar beets, such as the height of plants and stem girth along with lengths and fresh weights of leaves, roots, and whole plants. The recorded findings demonstrated that at the fourth week of germination, CA foliar feeding did not produce a statistically significant impact on the leaf width and plant height of sugar beets. However, CA produced 17%, 14%, and 35% taller plants at the six, eight, and ten weeks of germination, respectively. Likewise, the control treatment recorded 32% and 30% smaller leaf widths of sugar beets compared to the CA foliar feeding treatment at the 8th and 10th weeks of germination, respectively. In addition, it was found that CA foliar feeding was effective in enhancing the stem length and root length by 16% and 38%, respectively compared to the control under SS. Moreover, CA foliar feeding enhanced stem diameter (26%) and root fresh weight (29%) compared to the control treatment. As far as leaf length and fresh weight along with whole plant fresh weight were concerned, foliar feeding of CA demonstrated its effectiveness by producing 32%, 21%, and 42% greater values, respectively compared to the control treatment. Therefore, CA foliar feeding could serve as a potent strategy to mitigate the deleterious effects of saline stress and boost the vegetative growth of hydroponically grown sugar beets. [ABSTRACT FROM AUTHOR]
- Published
- 2025
- Full Text
- View/download PDF
26. XGBoost Based Multiclass NLOS Channels Identification in UWB Indoor Positioning System.
- Author
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Majeed, Ammar Fahem, Arsat, Rashidah, Baharudin, Muhammad Ariff, Abdul Latiff, Nurul Mu'azzah, and Albaidhani, Abbas
- Subjects
INDOOR positioning systems ,SEARCH algorithms ,LOCATION-based services ,GENETIC algorithms ,MACHINE learning ,BOOSTING algorithms - Abstract
Accurate non-line of sight (NLOS) identification technique in ultra-wideband (UWB) location-based services is critical for applications like drone communication and autonomous navigation. However, current methods using binary classification (LOS/NLOS) oversimplify real-world complexities, with limited generalisation and adaptability to varying indoor environments, thereby reducing the accuracy of positioning. This study proposes an extreme gradient boosting (XGBoost) model to identify multi-class NLOS conditions. We optimise the model using grid search and genetic algorithms. Initially, the grid search approach is used to identify the most favourable values for integer hyperparameters. In order to achieve an optimised model configuration, the genetic algorithm is employed to fine-tune the floating-point hyperparameters. The model evaluations utilise a wide-ranging dataset of real-world measurements obtained with a Qorvo DW1000 UWB device, covering various indoor scenarios. Experimental results show that our proposed XGBoost achieved the highest overall accuracy of 99.47%, precision of 99%, recall of 99%, and an F-score of 99% on an open-source dataset. Additionally, based on a local dataset, the model achieved the highest performance, with an accuracy of 96%, precision of 96%, recall of 97%, and an F-score of 97%. In contrast to current machine learning methods in the literature, the suggestion model enhances classification accuracy and effectively addresses the NLOS/LOS identification as a multiclass propagation channel. This approach provides a robust solution with generalisation and adaptability across various dataset types and environments for more reliable and accurate indoor positioning technologies. [ABSTRACT FROM AUTHOR]
- Published
- 2025
- Full Text
- View/download PDF
27. Prevalence of Bullying among Primary School Pupils in Al-Najaf City, Iraq.
- Author
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Abed AL-Shibli, Essam Najim and AL-Nasrawii, Maytham Salim
- Subjects
BULLYING prevention ,PRIMARY schools ,HEALTH outcome assessment ,MEDICAL personnel ,MEDICAL care - Abstract
Background: Bullying is a harmful behavior that involves repeated aggressive actions intended to cause harm or distress to an individual. It is a major public health concern affecting children and adolescents. There is no local relevant study regarding this issue. Objectives: To determine the prevalence of bullying in primary schools. Materials and methods: A cross-sectional study was carried out from 1
st September 2023 to the 10th of April 2024 for a sample consisting of 1216 pupils. The sample of the present study was a group of pupils in fifth and sixth primary school classes for both sexes; those were found in the selected schools out of 201 schools currently found at Al-Najaf city, Iraq. The data collecting tools were direct interviews with the participants and a questionnaire composed of two parts, the first consisting of the demographic characteristics data and the second being the bullying items among primary school pupils. Results: The prevalence of bullying was 81.7%. The study shows 3.5% bullyer, 37.3% bullied, 41% bullyer/victim, and 18.3% were non-victims non bullyer. With the exception of the number of close friends in class, all other items were related to (P-value < 0.05) the prevalence of bullying roles (bullyer, bullied, and bullyer/victim). Conclusion: The study found a high prevalence of bullying among primary school students in Najaf City, which is concerning. An inverse relationship between protective factors and the prevalence of bullying has been identified. To address this, teachers should dedicate class time to discussing the harms of bullying and promote tolerance, while also supporting strategies to reduce school violence. [ABSTRACT FROM AUTHOR]- Published
- 2025
- Full Text
- View/download PDF
28. Efficient degradation of organic pollutants without any external assistance over a wide pH range using carbon vacancy-modified Fe–N–C catalysts.
- Author
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Li, Feng, Zhao, Kairen, Jin, Yan, and Li, Baoxin
- Published
- 2024
- Full Text
- View/download PDF
29. Seed Biotechnologies in Practicing Sustainable Agriculture: Insights and Achievements in the Decade 2014–2024.
- Author
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Tiwari, Pragya and Park, Kyeung-Il
- Subjects
SUSTAINABLE agriculture ,MULTIWALLED carbon nanotubes ,SEED technology ,CROPS ,SUSTAINABILITY - Abstract
While agricultural crops remain at the forefront of addressing global food demands and malnutrition, depleting resources, fluctuating climatic conditions, and the adverse impact of biotic/abiotic stresses define a major challenge. Plant seeds comprise an important starting material for plant propagation, in vitro generation, and conservation, and are crucial factors in determining the quality and yield of the desired crops. The expanding horizon of precision agriculture suggests that high-quality seeds could promote crop productivity up to 15–20 percent, attributed to emerging biotechnological innovations in seed science and research. In addition, seed science comprises an integral aspect of sustainable development goals (SDGs), and plays a crucial role in Climate Action (SDG 13) and Zero hunger (SDG 2). While synthetic seed technologies highlight prospects in the propagation and conservation of key plant species, seed biopriming to address environmental stresses is innovative in climate-smart agriculture. The article discusses key developments in advanced seed biotechnologies, ranging from nano-enabled seed treatments to the non-coding RNA-mediated determination of seed traits and genetic manipulation of seeds for quality improvement. Research employing multi-omics, bioinformatics, and seed biopharming for the enhanced production of high-value metabolites is opening new avenues in seed biology and biotechnology research. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
30. Cómo aborda el modelo de conservación de Levine las necesidades específicas de las mujeres posparto en relación con la actividad física? : revisión sistemática.
- Author
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Toyibah, Afnani, Kurniasari Solikhah, Fitriana, Hamarno, Rudi, Utami, Ngesti W., Iafi Almutairi, Reem, and Surya Aditya, Ronal
- Subjects
POSTNATAL care ,MEDICAL personnel ,ENERGY conservation ,DATABASE searching ,CINAHL database - Abstract
Copyright of Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación is the property of Federacion Espanola de Asociaciones de Docentes de Educacion Fisica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
- Full Text
- View/download PDF
31. Enhanced structural, magnetic, and dielectric properties in Cr3+-substituted Mg0.5R0.5Fe1.5Cr0.5O4 (R = Cu, Zn) ferrites.
- Author
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Parajuli, D., Raju, M. K., Reddy, T. Amaranatha, Shanmukhi, P. S. V., Ratnaraju, M., Chohan, Jasgurpreet Singh, Murali, N., Samatha, K., Ramesh, Avala, and Manepalli, R. K. N. R.
- Subjects
DIELECTRIC properties ,POLARIZED electrons ,MAGNETIC properties ,ELECTROMAGNETIC shielding ,LATTICE constants - Abstract
This study examines the structural, microstructural, magnetic, and dielectric properties of Cr
3+ -substituted ferrites, specifically Mg0.5 Cu0.5 Fe1.5 Cr0.5 O4 and Mg0.5 Zn0.5 Fe1.5 Cr0.5 O4 , synthesized using the solid-state reaction method. Structural and phase purity assessments were conducted via x-ray diffraction (XRD), Scanning Electron Microscopy (SEM), Fourier Transform Infrared (FTIR) spectroscopy, and Vibrating Sample Magnetometry. XRD patterns confirmed the formation of a single-phase cubic spinel structure in both ferrites, with derived lattice parameters (8.402 and 8.497 Å) and crystallite sizes (44.70 and 30.05 nm) supporting consistent structural integrity. SEM analysis in association with ImageJ software showed grain sizes between 732 and 324 nm, while FTIR spectra revealed characteristic tetrahedral and octahedral vibration bands. Notably, the saturation magnetization increased significantly with Cu2+ concentration, from 38.67 to 60.45 emu/g, indicating an enhancement in magnetic properties. The dielectric behavior, analyzed over a 100–105 Hz range, exhibited Maxwell–Wagner interfacial polarization and electron hopping effects between Fe2+ and Fe3+ ions, contributing to typical dispersion patterns. This improvement in magnetic and dielectric properties, particularly in the Cu-doped samples, underscores the effectiveness of Cr3+ substitution in tuning material characteristics. The findings suggest that these modified ferrites hold promise for high-frequency electronic applications, such as inductors, transformers, and electromagnetic interference shielding materials, where both magnetic stability and efficient dielectric performance are critical. This research contributes valuable insights into the development of advanced ferrites for multifunctional electronic devices. [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
- View/download PDF
32. Psychosocial Experience of Patients with Diabetes Mellitus: An Interpretative Phenomenological Analysis.
- Author
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Ubaidillah, Zaqqi, Wulandari, Ratna, and Ruhyanudin, Faqih
- Subjects
PEOPLE with diabetes ,ANXIETY ,SOCIAL support ,SELF-consciousness (Awareness) ,MENTAL health - Abstract
Psychological problems experienced by diabetic patients need to be known and handled properly by health workers because distress will have a negative impact on the patient's diabetes management behavior. This study aims to capture and describe in detail the psychosocial experience of diabetes patients. This research is qualitative research with a phenomenological approach. Purposive sampling was used to select participants who had an experience following the phenomenon and research objectives. The number of participants in this study was 10 participants. This research was conducted in the Malang City Ciptomulyo Health Center area from March to May 2021. The analysis of this research was interpretative psychological analysis (IPA). The four themes of the psychosocial experience found in people with diabetes mellitus are fear and worry when diagnosed with diabetes, sad and disturbed by changes in body appearance and function, social support providing appeasement and self-awareness and support of others for diabetes management. Living with diabetes can be a difficult and overwhelming experience that often leads to fear and anxiety. Furthermore, the physical changes caused by diabetes can disrupt daily routines and affect mental health. Health workers should address both the physical and psychological effects of diabetes and encourage patients to take responsibility for their treatment to improve overall health. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
33. Mental Health Literacy and Attitudes Towards Mental Health Problems Among College Students, Nepal.
- Author
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Poudel, Dev Bandhu, Sharif, Loujain Saud, Acharya, Samjhana, Mahsoon, Alaa, Sharif, Khalid, and Wright, Rebecca
- Subjects
HEALTH attitudes ,PEARSON correlation (Statistics) ,HEALTH literacy ,MENTAL illness ,HEALTH self-care - Abstract
(1) Background: Research on mental health literacy (MHL) and attitudes toward mental health problems (ATMHP) among non-medical college students in Nepal is limited. This study examined the relationship between MHL and ATMHP, considering demographic variables and familiarity with mental health issues; (2) Methods: We conducted a cross-sectional survey with 385 college students from Chitwan and Kathmandu, Nepal, using opportunity sampling. Descriptive and inferential statistics examined demographic differences, while Pearson's correlation assessed relationships among latent variables; (3) Results: No relationship was found between MHL and ATMHP (r = −0.01, p = 0.92). Females had greater awareness of stereotypes (p = 0.025, g = 0.24). Hotel management students showed better self-help strategies (p = 0.036, d = 0.46). Public college students scored higher in self-help strategies than government (p = 0.036, d = −0.32) and private college students (p = 0.02, d = −0.32). Non-employed students outperformed employed ones in self-help strategies (p = 0.002, g = −0.46). Other demographic factors showed no significant relationships; (4) Conclusions: MHL and ATMHP were unrelated, indicating that increasing MHL alone may not improve attitudes. Multidimensional interventions combining education and experiential learning are needed. Certain demographic factors influenced stereotypes and self-help strategies, while others showed no significant impact. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
34. Vision-based approach for human motion detection and smart appliance control.
- Author
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Swami, Siddharth, Singh, Rajesh, Gehlot, Anita, Iqbal, Mohammed Ismail, Sharma, Sameer Dev, Kumar, Dharmendra, and Shah, Sanjeev Kumar
- Published
- 2024
- Full Text
- View/download PDF
35. Weizmannia coagulans BC99 affects valeric acid production via regulating gut microbiota to ameliorate inflammation and oxidative stress responses in Helicobacter pylori mice.
- Author
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Zhai, Shirui, Gao, Yinyin, Jiang, Yiru, Li, Yuwan, Fan, Qiuxia, Tie, Shanshan, Wu, Ying, and Gu, Shaobin
- Subjects
GUT microbiome ,VALERIC acid ,GASTRIC mucosa ,COLONIZATION (Ecology) ,OXIDATIVE stress ,HELICOBACTER pylori - Abstract
Helicobacter pylori is a highly prevalent pathogen in human gastric mucosa epithelial cells with strong colonization ability. Weizmannia coagulans is a kind of active microorganism that is beneficial to the improvement of host gut microbiota balance and can prevent and treat intestinal diseases. We investigated the beneficial effects of W. coagulans BC99 in H. pylori infected mice and measured inflammation response, oxidative stress, and gut microbiota. Results showed that BC99 could alleviate the gastric inflammation, inhibit the increasing of inflammation parameters endotoxin, interleukin‐10, transforming growth factor‐β, and interferon‐γ and oxidative stress myeloperoxidase and malondialdehyde, promote the levels of superoxide dismutase and catalase. Furthermore, 16S rRNA gene sequencing analysis revealed that BC99 reversed the change of gut microbiota by reducing the abundance of Olsenella, Candidatus_Saccharimonas, Monoglobus, and increasing the abundance of Tyzzerella. Meanwhile, BC99 caused elevated levels of Ligilactobacillus and Lactobacillus. In view of the beneficial effect of BC99 on the content of short‐chain fatty acid, valeric acid with sodium valerate interfered with H. pylori infection in mice found that valeric acid had a good restorative effect of H. pylori infection relating inflammation and oxidative stress responses. These results suggest that W. coagulans BC99 can be used as a potential probiotic to prevent and treat H. pylori infection by regulating the inflammation, oxidative stress, and gut microbiota. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
36. Cómo se centra la perspectiva de las partes interesadas en la enfermería universitaria en enfermería deportiva?: estudio cualitativo en el desarrollo curricular.
- Author
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Yusuf, Ah, Aditya, Ronal Surya, Rahmatika, Qory Tifani, Budi Sunaryo, Eri Yanuar Akhmad, Masfi, Achmad, Afiani, Nurma, Widjayanti, Yhenti, Ramadhan, Muhammad Putra, Evi, Nurul, AlMutairi, Reem Iafi, Alruwaili, Abdullah Saleh, and Al Razeeni, Daifallah M.
- Subjects
CAREER development ,NURSING education ,STAKEHOLDER analysis ,PHENOMENOLOGY ,NURSES ,NURSES' attitudes - Abstract
Copyright of Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación is the property of Federacion Espanola de Asociaciones de Docentes de Educacion Fisica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
37. Potential biological and optoelectronic applications of AgO:ZnO nanocomposite synthesized by green approach.
- Author
-
Talib, Waleed R., Sudhakaran, Ashwin, Sudhakaran, Allwin, and Mohammed, Raghad S.
- Abstract
This study aimed to estimate the potential optoelectronic and biological properties of AgO:ZnO nanocomposite synthesized by an environmentally friendly method. The synthesis of nanocomposite was carried out by reducing silver nitrate with Salvia hispanica extra, and zinc nitrate was mixed to produce the nanocomposite. An extensive examination was carried out on the physical and biological characteristics of the synthesized nanocomposite using several approaches. The EDX analysis confirmed the purity of the synthesized sample via the presence of elements Ag, Zn, and O only in the nanocomposite. The crystal structure of nanocomposite with hexagonal phase and average crystallite size of 56.8 nm was confirmed by X-ray diffraction. The formation of fibrous AgO:ZnO nanoparticles with an average diameter of 1.021 ± 0.6 μm was indicated by field-emission scanning electron microscopy examination. The optical property investigation revealed that the nanocomposite had a wide absorption band with an absorption peak at 425 nm. The observed phenomenon was attributable to the occurrence of electronic transitions within the material. The direct bandgap energy of 2.90 eV and the Urbach energy of 0.456 eV for the nanocomposite demonstrated the presence of defect states in the bandgap region. The measured values of the conduction band edge (E
CB ) and valence band edge (EVB ) additionally revealed the material's electronic structure. The biological potential of AgO:ZnO nanocomposite was evaluated by the agar well diffusion technique against Gram-positive and Gram-negative bacteria and a fungus. The extensive investigation of the AgO:ZnO nanocomposite's characteristics has shown its potential for use in a wide range of photonic, optoelectronic, and biological applications. [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
- View/download PDF
38. Wind and Photovoltaic Power Generation Forecasting for Virtual Power Plants Based on the Fusion of Improved K-Means Cluster Analysis and Deep Learning.
- Author
-
Qiu, Zhichao, Tian, Ye, Luo, Yanhong, Gu, Taiyu, and Liu, Hengyu
- Abstract
Virtual power plants (VPPs) have emerged as an innovative solution for modern power systems, particularly for integrating renewable energy sources. This study proposes a novel prediction approach combining improved K-means clustering with Time Convolutional Networks (TCNs), a Bi-directional Gated Recurrent Unit (BiGRU), and an attention mechanism to enhance the forecasting accuracy of wind and photovoltaic power generation in VPPs. The proposed TCN-BiGRU-Attention model demonstrates superior predictive performance compared to traditional models, achieving high accuracy and robustness. These results provide a reliable basis for optimizing VPP operations and integrating renewable energy sources effectively. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
39. Biogenic biocompatible silver nanoparticles: a promising antibacterial agent.
- Author
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Chandraker, Sandip Kumar and Kumar, Ravindra
- Published
- 2024
- Full Text
- View/download PDF
40. Awareness of Mental Health, Attitudes about Mental Illness, and Utilization Barriers of Mental Health Services among Adults in Najran Region, Kingdom of Saudi Arabia.
- Author
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Hafez, Sameer Hamdy, Mohamed, Noha Ahmed, Osman Abdalla, Abdalla Mohamed Ahmed, Gomaa, Salma Mohammed, Mohammed Ahmed, Khalda Ahmed, Merghani Ahmed, Magda Mubarak, Mohamed, Ishraga A., Ahmed Balola, Hamza Hussain, Abdullah Alwadei, Hanan Saad, Abdelrahman Ahmed, Mohammed Ateeg, Suleman, Ahood Mofarh, and Elrefaey, Samah Ramadan
- Subjects
COMPETENCY assessment (Law) ,MENTAL illness treatment ,HEALTH literacy ,HEALTH services accessibility ,CROSS-sectional method ,ATTITUDES toward illness ,MENTAL health services ,QUESTIONNAIRES ,RESEARCH methodology ,PSYCHOMETRICS ,ADULT education workshops ,ADULTS - Abstract
Background: Lack of awareness and negative perceptions regarding mental well-being and mental diseases among high-risk population prevents them from seeking help. Purpose: The aim of the current study is to assess awareness of mental health, attitudes towards mental illness, and utilization barriers of mental health services among adults in Najran region, Kingdom of Saudi Arabia. Methods: To meet the study's objectives, a crosssectional design was employed, utilizing a convenience sample of 400 participants. The research involved a validated survey tool that featured structured questions covering demographic information, the Mental Health Knowledge Questionnaire (MHKQ), the Community Attitudes Toward Mental Illness Inventory (CAMI), which includes 40 Likertscale items, and the Barriers to Mental Health Services Questionnaire. Results: The results of the current study revealed that most of the participants had unsatisfactory knowledge: 245 (61.3%). A significant majority showed negative attitudes toward mental illness: 290 (72.5%). The main barriers to accessing mental health services were; stigma: 135 participants (33.7%), unwanted intervention concerns: 82 (20.5%), financial problems: 78 (19.5%), access difficulties: 45 (11.3%), and confidentiality concerns: 60 participants (15%). Furthermore, a significant positive connection existed between knowledge scores and positive attitudes (r=0.598, p= 0.0001). Conclusion: The current study shed light on the concerning lack of knowledge and the prevalent negative attitudes among the studied sample. The main barriers to accessing mental health services were stigma, unwanted intervention concerns, and financial issues. Implications for Nursing: The findings underscore the urgent need for targeted interventions to address these issues, such as organizing workshops and seminars to educate the public about mental health, as well as about mental illness, and promote positive mental health practices. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
41. Nanotechnology for sustainability of agriculture and environment: Green synthesis and application of nanoparticles -- A review.
- Author
-
KANWAL, ANJALI, SHARMA, INDU, SINGH, RAJ, and RANA, M. K.
- Subjects
SUSTAINABLE agriculture ,HEAVY metal toxicology ,NATURAL resources ,CROP yields ,AGRICULTURAL climatology ,PRECISION farming - Abstract
Moreover, with the continuous population increase worldwide, there is more demand of food and other daily necessities, which require double agriculture production to provide adequate food for humanity from the same available natural resources. Therefore, looking for new techniques to combat various challenges is instantly needed to sustain crop production and provide enough food for humanity. The use of nanotechnology in agriculture field represents an important tool for consistent production of agriculture crops and assists farmers with new practice management systems such as precision agriculture systems, the aim of which is to increase productivity and reduce expenses. Nanotechnology plays an important role in altering agriculture food production. The particles ranging from 1 to 100 nm are accounted as nanoparticles, which usually have high surface energy, big surface area and quantum quarantine. Most notably, nanoparticles increase crop yield by increasing the effectiveness of agricultural inputs to enable site-targeted, controlled nutrient delivery, assuring the least amounts of agroinputs needed. Additionally, the main aim in agricultural production is to facilitate plants' faster adaptation to the increasingly severe climate change factors, such as high temperatures, low water availability, salinity, alkalinity and environmental pollution with heavy metals, without jeopardizing the delicate ecosystems that are currently in place. This review illustrates the effect of numerous nanoparticles on diverse plants of many concentrations, sizes and shapes. The molecular and genetic response to NPs, their method of action and their interactions with biomolecules should be the main areas of study in the future. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
42. Melatonin Dose-Mediated Increment in Growth, Floral Production, Essential Oils Yield and Composition in Marigold.
- Author
-
Yousif, Muhammad, Ahmad, Tanveer, Alasasfa, Muawya A., Al Zoubi, Omar Mahmoud, Saeed, Tahir, Ahmad, Iftikhar, and Iqbal, Muhammad A.
- Subjects
ESSENTIAL oils ,RF values (Chromatography) ,SOMATOTROPIN ,ANALYTICAL chemistry ,MARIGOLDS - Abstract
Globally, African marigold (MG) derived essential oils (EOs) have attained an immense economic pertinence in the flavor, fragrance, food, medicinal, and floricultural industries, which necessitate boosting its production on a commercial scale. Therefore, we aimed to assess varying levels (0, 50, 100, 150, and 200 mg L
-1 ) of exogenously applied melatonin (MT) as a growth hormone to trigger growth, flower yield, and EOs of MG. The MT was applied as a foliar spray after thirty days of transplantation of MG plants and repeated thrice at fifteen-day intervals. The results depicted that exogenous MT (150 mg L-1 ) recorded the maximum plant height and leaves number along with fresh and dry weights of leaves and roots. The same treatment exhibited 66%, 64%, and 18% higher flower fresh and dry weights and flower yield respectively, than the control. Additionally, MT remained effective in reducing days taken to bud emergence and flowering, while flower retention duration increased by 11 days. Following the trend of vegetative growth traits, foliar-applied MT (150 mg L-1 ) remained unmatched in terms of physiological attributes (transpiration rate, stomatal conductance, chlorophyll a, and b contents) of MG. Moreover, for EOs extracted from fresh and dry flowers and leaves, this treatment remained effective by producing 77%, 73%, 53%, and 85% higher content, respectively than the control. Finally, the chemical profiling analyses detected eighty-seven chemical constituents (Caryophyllene oxide was the most dominant compound, and cis-Z-alpha-Bisabolene epoxide followed it) in MG flowers. In terms of the retention time of different chemical compounds in MG flowers, Calarene epoxide had the highest retention time of 19.75 minutes among major compounds. Based on these results, 150 mg L-1 dose of MT may be recommended to growers for boosting MG growth, floral yield and EOs content sustainably. [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
- View/download PDF
43. Application of cisplatin and other platinum-containing drugs in cancer therapy: Comprehensive review.
- Author
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A.S, Arul Prishya, Chopra, Lalita, Manikanika, Bose, Diotima, Chauhan, Ashish Singh, Alhadrawi, Merwa, Chauhan, Abhineet, and Kumar, Dharminder
- Published
- 2024
- Full Text
- View/download PDF
44. Biomaterial amendments improve nutrient use efficiency and plant growth.
- Author
-
Ying LIU, MANZOOR, Natasha, Miao HAN, Kun ZHU, and Gang WANG
- Subjects
GREENHOUSE gases ,SUSTAINABLE agriculture ,CLIMATE change mitigation ,SOIL amendments ,AGRICULTURE ,MICROBIAL inoculants - Abstract
The achievement of global food security faces exceptional challenges due to the rapid population growth, land degradation and climate change. Current farming practices, including mineral fertilizers and synthetic pesticides, alone are becoming insufficient to ensure long-term food security and ecosystem sustainability. The lack of robustness and reliability of conventional approaches warrants efforts to develop novel alternative strategies. Bio-based management strategies offer promising alternatives for improving soil health and food productivity. For example, microbial inoculants can enhance nutrient availability, crop production and stress resistance while also remediating contaminated soils. Nanobiotechnology is a promising strategy that has great potential for mitigating biotic and abiotic stresses on plant toward sustainable agriculture. Biochar (including modified biochar) serves as an effective microbial carrier, improving nutrient availability and plant growth. Also, biochar amendments have been demonstrated to have great potential facilitating soil organic carbon sequestration and mitigating greenhouse gas emissions and therefore contribute to climate change mitigation efforts. This review examines the integration of microbial inoculants, nano-fertilizers and biochar, which demonstrates as a promising strategy to enhance soil health, crop productivity and environmental sustainability. However, overcoming challenges related to their mass production, application and potential risks remains crucial. Future research should focus on optimizing these bioamendment strategies, evaluating their economic viability and developing robust regulatory frameworks to ensure safe and effective agricultural implementation. [ABSTRACT FROM AUTHOR]
- Published
- 2025
- Full Text
- View/download PDF
45. Multi band multi polarised fractal antenna for white space TV band.
- Author
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Sharma, Richa, De, Asok, and Raghava, N.S.
- Subjects
ANTENNAS (Electronics) ,ELECTROMAGNETIC waves ,ANTENNA design ,SNOWFLAKES ,BANDWIDTHS - Abstract
Designing a fractal antenna for white space TV band frequencies is the main goal of the suggested work. In this design 4 iteration Koch snowflakes patch is used to get multiband. As the number of iterations increased size of the antenna is going to reduce. Further 4
th iteration Koch snowflakes slots have been created in the patch. By introducing a fourth iteration cross slot into the ground plane, three bands have been created. Circular polarisation is attained through the incorporation of cross slots in the ground plane, inducing a phase shift between vertically and horizontally polarised electromagnetic waves. The antenna primarily operates within the last frequency bands (686–806 MHz) with linear polarisation. However, it can also function in the initial frequency band (487–540 MHz) with left-hand circular polarisation. The physical size if antenna is reduced by 38 mm with a gain of 4.5dBi. Axial ratio bandwidth (481–552 MHz) is 71 MHz. Axial ratio bandwidth is 18 MHz more as compared to impedance bandwidth. The same antenna can work in linear polarisation as well as circular polarisation. Multi-polarised, multiband antenna with impedance bandwidth of 10.3% (1st band) and 16.08% (last band) is designed for white space TV band frequencies. [ABSTRACT FROM AUTHOR]- Published
- 2025
- Full Text
- View/download PDF
46. Chitosan-based NPK nanostructure for reducing synthetic NPK fertilizers and improving rice productivity and nutritional indices.
- Author
-
Elshayb, Omnia M., Ghazy, Hassnaa A., Wissa, Mariam T., Farroh, Khaled Y., Wasonga, Daniel O., and Seleiman, Mahmoud F.
- Subjects
SUSTAINABLE agriculture ,NITROGEN fertilizers ,SYNTHETIC fertilizers ,FERTILIZER application ,AGRICULTURAL productivity - Abstract
Researchers have repeatedly emphasized how urgently we have to decrease the massive nitrogen fertilizer consumption to support agricultural productivity and maintain a sustainable ecosystem. Using chitosan (CS) as a carrier for slow release is considered a potential tool for reducing synthetic fertilizer and improving crop productivity. Therefore, two field experiments were arranged in a randomized complete block design to investigate the effects of seven treatments including synthetic fertilizer and exogenous application of chitosan-based NPK nano-structure (Ch/NPs-NPK) on growth, productivity, and nutrient uptake traits of rice as a worldwide strategy crop during 2022 and 2023 growing seasons. The experimental treatments were: T1 = full recommended synthetic NPK (recommended urea, superphosphate, potassium sulfate; control treatment), T2 = 70% of T1 + Ch/NPs-NPK 100 ppm, T3 = 70% of T1+ Ch/NPs-NPK 200 ppm, T4 = 70% of T1+ Ch/NPs-NPK 300 ppm, T5 = 30% of T1+ Ch/NPs-NPK 100 ppm, T6 = 30% of T1+ Ch/NPs-NPK 200 ppm, and T7 = 30% of T1 + Ch/NPs-NPK 300 ppm. The results revealed that T4 (i.e., 70% of recommended NPK+ Ch/NPs-NPK 300 ppm) and T1 (full recommended synthetic NPK) resulted in the highest and most significant growth and yield traits of rice as well as nutrient grain contents compared to other treatments. Therefore, combining 70% of recommended NPK with Ch/NPs-NPK 300 ppm as an exogenous application can be a smart choice for reducing synthetic NPK fertilizers by 30% in paddy fields without producing a significant decline in terms of growth, yield characteristics, or nutrient grain contents when applying the full recommended synthetic NPK. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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47. I engage in physical activity while operating a wheelchair.: a systematic review of stroke patients.
- Author
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Yunus, Moch, Wahyudi, Nanang Tri, Darmawan, Arief, Ihsan, Nurul, Jamil, Mohd, Sulistyorini, Anita, Aditya, Ronal Surya, Nurzahra, Fesya Khaifa, Alruwaili, Abdullah Saleh, Al Razeeni, Daifallah M., and AlMutairi, Reem Iafi
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STROKE patients ,PHYSICAL activity ,WHEELCHAIRS ,MEDICAL personnel ,STROKE - Abstract
Copyright of Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación is the property of Federacion Espanola de Asociaciones de Docentes de Educacion Fisica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
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48. Assessment of the in vitro metabolic stability of CEP-37440, a selective FAK/ALK inhibitor, in HLMs using fast UPLC–MS/MS method: in silico metabolic lability and DEREK alerts screening.
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Attwa, Mohamed W., AlRabiah, Haitham, Abdelhameed, Ali S., and Kadi, Adnan A.
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ANAPLASTIC lymphoma kinase ,FOCAL adhesion kinase ,ORGANS (Anatomy) ,LIVER microsomes ,PERMUTATION groups - Abstract
Introduction: CEP-37440 was synthesized and supplied by the research and development division of Teva Branded Pharmaceutical Products (West Chester, PA, United States). CEP-37440 represents a newly developed compound that exhibits selectivity inhibition of Focal Adhesion Kinase and Anaplastic Lymphoma Kinase FAK/ALK receptors, demonstrating novel characteristics as an orally active inhibitor. The simultaneous inhibition of ALK and FAK can effectively address resistance and enhance the therapeutic efficacy against tumors through a synergistic mechanism. Methods: The objective of this research was to create an LC-MS/MS method that is precise, efficient, environmentally friendly, and possesses a high level of sensitivity for the quantification of CEP-37440 in human liver microsomes (HLMs). The aforementioned approach was subsequently employed to evaluate the metabolic stability of CEP-37440 in HLMs in an in vitro setting. The validation procedures for the LC-MS/MS analytical method in the HLMs were performed following the bio-analytical method validation guidelines set out by the US-FDA. The AGREE program was utilized to assess the ecological impacts of the current LC-MS/MS methodology. Results and Discussion: The calibration curve linearity was seen in the range of 1–3000 ng/mL. The inter-day accuracy (% RE) exhibited a range of −2.33% to 3.22%, whilst the intra-day accuracy demonstrated a range of −4.33% to 1.39%. The inter-day precision (% RSD) exhibited a range of 0.38% to 3.60%, whilst the intra-day precision demonstrated a range of 0.16% to 6.28%. The determination of the in vitro half-life (t
1/2 ) and moderate intrinsic clearance (Clint ) of CEP-37440 yielded values of 23.24 min and 34.74 mL/min/kg, respectively. The current manuscript is considered the first analytical study for CEP-37440 quantification with the application to metabolic stability assessment. These results suggest that CEP-37440 can be categorized as a pharmaceutical agent with a moderate extraction ratio. Consequently, it is postulated that the administration of CEP-37440 to patients may not lead to the accrual of dosages within the human organs. According to in silico P450 metabolic and DEREK software, minor structural alterations to the ethanolamine moiety or substitution of the group in drug design have the potential to enhance the metabolic stability and safety profile of novel derivatives in comparison to CEP-37440. [ABSTRACT FROM AUTHOR]- Published
- 2024
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49. Blocking ACSL6 Compromises Autophagy via FLI1‐Mediated Downregulation of COLs to Radiosensitize Lung Cancer.
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Ding, Wen, Bao, Shijun, Zhao, Qingwei, Hao, Wei, Fang, Kai, Xiao, Yanlan, Lin, Xiaoting, Zhao, Zhemeng, Xu, Xinyi, Cui, Xinyue, Yang, Xiwen, Yao, Liuhuan, Jin, Hai, Zhang, Kun, and Guo, Jiaming
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TRANSCRIPTION factors ,LUNG cancer ,AUTOPHAGY ,CANCER radiotherapy ,TUMOR growth - Abstract
Lung cancer (LC) is the leading cause of cancer‐related mortality worldwide. Radiotherapy is the main component of LC treatment; however, its efficacy is often limited by radioresistance development, resulting in unsatisfactory clinical outcomes. Here, we found that LC radiosensitivity is up‐regulated by decreased expression of long‐chain acyl‐CoA synthase 6 (ACSL6) after irradiation. Deletion of ACSL6 results in significant elevation of Friend leukemia integration 1 transcription factor (FLI1) and a marked decline of collagens (COLs). Blocking of ACSL6 impairs the tumor growth and upregulates FLI1, which reduces the levels of COLs and compromises irradiation‐induced autophagy, leading to considerable therapeutic benefits during radiotherapy. Moreover, the direct interaction between ACSL6 and FLI1 and engagement between FLI1 and COLs indicates the involvement of the ACSL6‐FLI1‐COL axis. Finally, the potently adjusted autophagy flux reduces its otherwise contributive capability in surviving irradiation stress and leads to satisfactory radiosensitization for LC radiotherapy. These results demonstrate that enhanced ACSL6 expression promotes the aggressive performance of irradiated LC through increased FLI1‐COL‐mediated autophagy flux. Thus, the ACSL6‐FLI1‐Col‐autophagy axis may be targeted to enhance the radiosensitivity of LC and improve the management of LC in radiotherapy. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
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50. Solution-Processed Thin Film Transparent Photovoltaics: Present Challenges and Future Development.
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Liu, Tianle, Almutairi, Munerah M. S., Ma, Jie, Stewart, Aisling, Xing, Zhaohui, Liu, Mengxia, Hou, Bo, and Cho, Yuljae
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SEMICONDUCTOR nanocrystals ,SOLAR panels ,ELECTRICAL energy ,ELECTROCHROMIC windows ,SOLAR energy - Abstract
Highlights: Recent advancement in solution-processed thin film transparent photovoltaics (TPVs) is summarized, including perovskites, organics, and colloidal quantum dots. Pros and cons of the emerging TPVs are analyzed according to the materials characteristics and the application requirements on the aesthetics and energy generation. Promising TPV applications are discussed with emphasis on agrivoltaics, smart windows and facades. Electrical energy is essential for modern society to sustain economic growths. The soaring demand for the electrical energy, together with an awareness of the environmental impact of fossil fuels, has been driving a shift towards the utilization of solar energy. However, traditional solar energy solutions often require extensive spaces for a panel installation, limiting their practicality in a dense urban environment. To overcome the spatial constraint, researchers have developed transparent photovoltaics (TPV), enabling windows and facades in vehicles and buildings to generate electric energy. Current TPV advancements are focused on improving both transparency and power output to rival commercially available silicon solar panels. In this review, we first briefly introduce wavelength- and non-wavelength-selective strategies to achieve transparency. Figures of merit and theoretical limits of TPVs are discussed to comprehensively understand the status of current TPV technology. Then we highlight recent progress in different types of TPVs, with a particular focus on solution-processed thin-film photovoltaics (PVs), including colloidal quantum dot PVs, metal halide perovskite PVs and organic PVs. The applications of TPVs are also reviewed, with emphasis on agrivoltaics, smart windows and facades. Finally, current challenges and future opportunities in TPV research are pointed out. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
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