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Purpose: There is an urgent need for teacher preparation programs to equip teachers to teach in innovative and transformative ways, meeting the needs of diverse learners. Coaching is an instrumental tool for supporting change and development, especially in contexts with decentralized teacher preparation guidelines. Design/methodology/approach: This multicase study examines cross-institutional programmatic innovations for coaching teacher candidates (TCs) and centering equity using improvement science and equity coaching. The authors explore the networked improvement community's (NIC's) examination of problems of practice through plan-do-study-act cycles in three coaching contexts within and across seven institutions. Findings: Qualitative methods revealed that adapting coaching protocols can center equity and build equity-focused practices. This work highlights revisions to coaching within and across teacher preparation programs (TPPs), which the authors hope inspires extending equity-centered coaching and improvement science to new contexts. This cross-case analysis revealed program innovations for coaches, digital technologies and alignment. Practical implications: This study addresses ongoing challenges faced by TPPs in the United States, including TCs' understandings of equity in teaching and decentralized teacher preparation that results in varied and incongruent understandings about quality teaching. This study builds on previous scholarship that examines shifts in coaching practices by disrupting silos in TPPs as examined innovations. Originality/value: The paper offers a unique view of cross-institutional collaboration in coaching to improve transformative teaching experiences in teacher preparation field experiences.

Let \(G\) be a simple graph of order \(n\) with eigenvalues \(\lambda_1,\lambda_2,\cdots,\lambda_n\) and normalized Laplacian eigenvalues \(\mu_1,\mu_2,\cdots,\mu_n\). The Estrada index and normalized Laplacian Estrada index are defined as \(EE(G)=\sum_{k=1}^ne^{\lambda_k}\) and \(\mathcal{L}EE(G)=\sum_{k=1}^ne^{\mu_k-1}\), respectively. We establish upper and lower bounds to \(EE\) and \(\mathcal{L}EE\) for edge-independent random graphs, containing the classical Erdös-Rényi graphs as special cases.

Actualmente, en el noreste de la Península Ibérica, se conocen muy pocos restos humanos pertenecientes a las primeras comunidades agricultoras y pastoriles de inicios del neolítico. Buena parte de las evidencias que tenemos provienen de contextos arqueológicos excavados con anterioridad a los años 80, lo que supone que no se dispone del mismo acerbo de análisis que se realizan en la actualidad. La excavación realizada en Ca lEstrada viene a rellenar en parte ese vacío aportando no sólo dos nuevos enterramientos, sino también toda una serie de análisis tanto del continente como del contenido de las sepulturas. Su estudio nos ha permitido conocer biológicamente a dos de los sujetos protagonistas de aquella su historia, cómo fueron inhumados y qué objetos les acompañaban. Estamos, sin duda, ante una de las primeras evidencias funerarias de lo que ha venido a denominarse como la Cultura de los Sepulcros de fosa.

Abstract Purpose Women diagnosed with ductal carcinoma in situ (DCIS) face confusion and uncertainty about treatment options. The objective of this study was to determine whether there are differences in decisional conflict about treatment by age and race/ethnicity. Methods A cross-sectional survey was conducted of women (age ≥ 18) diagnosed with DCIS enrolled at Kaiser Permanente of Southern California. The Decisional Conflict Scale (DCS) measured personal perceptions of decision uncertainty, values clarity, and effective decision-making. We used a multivariable regression to study whether age, race, and ethnicity were associated with patient-reported DCS. Results 45% (N = 1395) of women who received the online survey, participated. The mean age was 56 (± 9.6) years, the majority were white. Compared to women younger than 50, women aged 60–69 reported lower overall DCS scores (-5.4; 95% CI -1.5 to -9.3). Women > 70 had lower values clarity scores (-9.0; 95% CI -2.8 to -15.2) about their treatment compared to women aged 50–59 and 60–69 (-7.1; 95% CI -2.9 to -11.3 and − 7.2; 95% CI -2.9 to -11.5) and likewise, lower effective decision-making scores (-5.4; 95% CI -1.7 to -9.2 and − 5.2; 95% CI -1.4 to -9.0) compared to women 70). Age based tailored discussions about treatment options, health education, and supportive decision-making interventions/tools may reduce decision conflict in future DCIS patients. Trade registration The IRB number is 10678.

Se realizó una revisión para conocer las principales manifestaciones de los síndromes frontales y prefrontales dependientes del tipo de lesión, sitio, etiología y extensión de la misma. Existen muchas causas potenciales de los síndromes del lóbulo frontal, que incluyen lesiones cerebrales traumáticas, accidentes cerebrovasculares, infecciones, tumores y afecciones degenerativas. Las opciones de tratamiento dependerán de la causa subyacente y pueden incluir medicamentos, terapia conductual y otras formas de rehabilitación.

Se describieron los principales hallazgos actuales relacionados con el proceso del envejecimiento. Para ello se realizó una revisión de artículos actualizados que abordan la temática. para valorar la necesidad de la educación en torno a esta etapa de la vida, desde la neuropsicología, en donde se enfatiza la importancia de un manejo integral, ya que se observa al individuo dentro de un contexto sociocultural que impacta en su funcionamiento cerebral. Conocer el desarrollo en el envejecimiento normal proporciona pautas para el abordaje integral del adulto mayor.

Se abordaron los tratamientos más frecuentes tanto farmacológicos como psicológicos y recientemente cognitivos para el trastorno por abuso con y sin substancias, así como los diferentes hallazgos neuropsicológicos relacionados con esta patología en población adulta. Las consecuencias tanto de la ingesta moderada y crónica afectan a todas las esferas del ser humano, además de tener consecuencias estructurales, de comportamiento, psicológicas y cognitivas a largo plazo, muchas de ellas irreversibles.

We describe a new generation of the high-performance GEOS-Chem (GCHP) global model of atmospheric composition developed as part of the GEOS-Chem version 13 series. GEOS-Chem is an open-source grid-independent model that can be used online within a meteorological simulation or offline using archived meteorological data. GCHP is an offline implementation of GEOS-Chem driven by NASA Goddard Earth Observing System (GEOS) meteorological data for massively parallel simulations. Version 13 offers major advances in GCHP for ease of use, computational performance, versatility, resolution, and accuracy. Specific improvements include (i) stretched-grid capability for higher resolution in user-selected regions, (ii) more accurate transport with new native cubed-sphere GEOS meteorological archives including air mass fluxes at hourly temporal resolution with spatial resolution up to C720 (∼ 12 km), (iii) easier build with a build system generator (CMake) and a package manager (Spack), (iv) software containers to enable immediate model download and configuration on local computing clusters, (v) better parallelization to enable simulation on thousands of cores, and (vi) multi-node cloud capability. The C720 data are now part of the operational GEOS forward processing (GEOS-FP) output stream, and a C180 (∼ 50 km) consistent archive for 1998–present is now being generated as part of a new GEOS-IT data stream. Both of these data streams are continuously being archived by the GEOS-Chem Support Team for access by GCHP users. Directly using horizontal air mass fluxes rather than inferring from wind data significantly reduces global mean error in calculated surface pressure and vertical advection. A technical performance demonstration at C720 illustrates an attribute of high resolution with population-weighted tropospheric NO2 columns nearly twice those at a common resolution of 2∘ × 2.5∘.

Introduction Type 2 diabetes mellitus (T2DM) is a powerful risk factor for cardiovascular disease (CVD), conferring a greater relative risk in women than men. We sought to examine sex differences in cardiometabolic risk factors and management in the contemporary cohort represented by the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE).Research design and methods GRADE enrolled 5047 participants (1837 women, 3210 men) with T2DM on metformin monotherapy at baseline. The current report is a cross-sectional analysis of baseline data collected July 2013 to August 2017.Results Compared with men, women had a higher mean body mass index (BMI), greater prevalence of severe obesity (BMI≥40 kg/m2), higher mean LDL cholesterol, greater prevalence of low HDL cholesterol, and were less likely to receive statin treatment and achieve target LDL, with a generally greater prevalence of these risk factors in younger women. Women with hypertension were equally likely to achieve blood pressure targets as men; however, women were less likely to receive ACE inhibitors or angiotensin receptor blockers. Women were more likely to be divorced, separated or widowed, and had fewer years of education and lower incomes.Conclusions This contemporary cohort demonstrates that women with T2DM continue to have a greater burden of cardiometabolic and socioeconomic risk factors than men, particularly younger women. Attention to these persisting disparities is needed to reduce the burden of CVD in women.Trial registration number ClinicalTrials.gov (NCT01794143)

The purpose of our study is to understand the attitude of the university students and teachers on the proposed ‘No Homework Policy” bill and how it could impact their studies and personal lives. The main objective was focused on (1) understanding the impact of the “No Homework Policy” bill to the students and teachers if the said policy bill will be implemented, (2) knowing the struggles of the students and teachers when it comes to homework, and (3) finding out the possible solution that could be implemented to lessen the struggles of both students and teachers regarding homework. A phenomenological design was used as an approach to conduct this study. Based on the results, most of the students are in favor of the said proposed bill. However, some teachers are against or undecided about it. The results also showed that the said proposed bill could affect both students and teachers in a positive and also a negative way. This study does not only help the student to realize how homework can impact their academic performances but also support the teacher to improve the capacity of their teaching skills and be aware of the struggles of the students with regards to homework.

Abstract Background Childhood obesity represents a global public health crisis: the number of obese children and adolescents (aged 5–19 years) worldwide has risen tenfold in the past four decades. The vast majority of overweight and obese children live in high-income countries, and low socio-economic status (SES) is a significant risk factor. Family Based Interventions (FBI) have demonstrated positive results in preventing obesity, although these results are strongly influenced by SES. Moreover, we still poorly understand how FBI can determine a positive trend in weight status in low-income communities. Therefore, there is an urgent need to define and evaluate innovative and multi-target projects to reduce obesity risk behaviors and health inequalities and the present study aims to present the study protocol of FIVALIN a FBI that pretends to achieve this goal. Methods We will conduct a quasi-experimental design within 60 Community Child Centers (CCC) in Barcelona metropolitan area. Each cluster (CCC) will be assigned by convenience to the intervention and control groups. For the whole study, a total of 810 children aged 8–12 years and 600 parents will be recruited during 3 consecutive editions (1st – 2019/2020; 2nd – 2020/2021; 3rd – 2021/2022) of 10 months each. The action is a regular multicomponent health-promotion intervention targeting children, families, and CCC. All activities are based on the Motivational Interviewing (MI) approach and will focus on promoting good dietary habits, physical activity, appropriate screen time and sleep duration, and psychological well-being. The control group participate in a unique workshop on general awareness of healthy lifestyles for families. We will perform a comparative analysis of the evolution of weight status, healthy lifestyles, and socioeconomic variables, between the intervention and control groups. Discussion There is a need for more evidence on how to target and evaluate holistic interventions in low SES families. Our multi-targeting intervention for obesity prevention tackles risky behaviors that go beyond diet and physical activity (PA). Therefore, future interventions can effectively promote all the behavioral domains that determine trends in the weight status. Trial registration ISRCTN Registry: ISRCRN12682870 . Registered 9 July 2020. Retrospectively registered. Protocol version: 30 April 2021, version 5.

The combustion of pure H2 in engines is still troublesome, needing further research and development. Using H2 and diesel in a dual-fuel compression ignition engine appears as a more feasible approach. Here we report an experimental assessment of performance and emissions for a single-cylinder, four-stroke, air-cooled compression ignition engine operating with neat diesel and H2-diesel dual-fuel. Previous studies typically show the performance and emissions for a specific operation condition (i.e. a fixed engine speed and torque) or a limited operating range. Our experiments covered engine speeds of 3000 and 3600 rpm and torque levels of 3 and 7 Nm. An in-house designed and built alkaline cell generated the H2 used for the partial substitution of diesel. Compared with neat diesel, the results indicate that adding H2 decreased the air-fuel equivalence ratio and the Brake Specific Diesel Fuel Consumption Efficiency by around 14–29 % and 4–31 %. In contrast, adding H2 increased the Brake Fuel Conversion Efficiency by around 3–36 %. In addition, the Brake Thermal Efficiency increased in the presence of H2 in the range of 3–37 % for the lower engine speed and 27–43 % for the higher engine speed compared with neat diesel. The dual-fuel mode resulted in lower CO and CO2 emissions for the same power output. The emissions of hydrocarbons decreased with H2 addition, except for the lower engine speed and the higher torque. However, the dual-fuel operation resulted in higher NOx emissions than neat diesel, with 2–6 % and 19–48 % increments for the lower and higher engine speeds. H2 emerges as a versatile energy carrier with the potential to tackle current energy and emissions challenges; however, the dual-fuel strategy requires careful management of NOx emissions.

Recent multidrug resistance in Pseudomonas aeruginosa has favoured the adaptation and dissemination of worldwide high-risk strains. In June 2018, 15 P. aeruginosa strains isolated from patients and a contaminated multi-dose meropenem vial were characterized to assess their association to an outbreak in a Mexican paediatric hospital. The strains were characterized by antibiotic susceptibility profiling, virulence factors’ production, and biofilm formation. The clonal relationship among isolates was determined with pulse-field gel electrophoresis (PFGE) and multi-locus sequence typing (MLST) sequencing. Repressor genes for the MexAB-OprM efflux pump were sequenced for haplotype identification. Of the strains, 60% were profiled as extensively drug-resistant (XDR), 33% as multidrug-resistant (MDR), and 6.6% were classified as sensitive (S). All strains presented intermediate resistance to colistin, and 80% were sensitive to aztreonam. Pyoverdine was the most produced virulence factor. The PFGE technique was performed for the identification of the outbreak, revealing eight strains with the same electrophoretic pattern. ST235 and ten new sequence types (STs) were identified, all closely related to ST233. ST3241 predominated in 26.66% of the strains. Twenty-five synonymous and seventeen nonsynonymous substitutions were identified in the regulatory genes of the MexAB-OprM efflux pump, and nalC was the most variable gene. Six different haplotypes were identified. Strains from the outbreak were metallo-β-lactamases and phylogenetically related to the high-risk clone ST233.