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P005 Dupilumab treatment normalizes skin barrier function in children aged 6 to 11 years with mode... Michael J. Cork 1, Donald Y.M. Leung 2, Peck Ong 3, Simon G. Danby 1, Marco Ramirez-Gama... 1 Sheffield Dermatology Research University of Sheffield, Department of Infection Immunity an... B Objectives: b To report the effect of dupilumab treatment in paediatric patients aged 6-11 years with moderate-to-severe atopic dermatitis (AD) on skin barrier function, clinician- and patient-reported outcomes. The lesions affected the upper leg (2 patients), neck (1 patient), shoulder (1 patient) and forehead (1 patient). P020 Dupilumab significantly improves patient reported outcomes in pediatric AD patients < 12 y... Michele Ramien 1,2, Danielle Marcoux 3,4, Eulalia Baselga 5, Marlies de Graaf 6, Alan D.... 1 Alberta Children's Hospital, Pediatrics and Medicine, Calgary, Canada; 2 University of Calg... B Objectives: b Dupilumab has proven to be effective in improving patient-reported outcomes for atopic dermatitis (AD) in paediatric patients in clinical trials. Comparison of epicardial adipose tissue thickness of paediatric patients with concomitant mod... Eduard Ambarchian 1, Vladislav Ivanchikov 1, Anastasia Kuzminova 1, Anna Shandra 1, Nikol... 1 Pediatrics and Child Health Research Institute in Petrovsky National Research Centre of Sur... B Objectives: b to identify the difference in the thickness of epicardial adipose tissue (EA) in the groups of patients with and without psoriasis B Method: b a total of 30 patients in the age between 8 and 16 years were separated in 2 groups of 15 people. The epidemiological, clinical and radiological characteristics of the patients are described, as well as their treatment and clinical course during the years of follow-up. B Results: b 8 paediatric patients and 1 adult patient with cerebral/spinal arteriovenous malformations or fistulas were identified. [Extracted from the article]

B Results b : Sixty patients (47.25%) had negative microscopy of skin scrapings examination, 30 patients (23.62%) had a positive result, and 37 patients (29.13%) have not been tested. In the 28 group-patient with negative microscopy of skin scrapings and negative dermoscopy exam, the epidemiological context was certain for 26 patients, with at least one infected member of the household, and only 10 patients have previously followed a scabicide treatment. P016 Assessment of the condition of pediatric patients with atopic dermatitis (AD) taken for thera... Eduard Ambarchian 1, Vladislav Ivanchikov 1, Anastasia Kuzminova 1, Nikolay Murashkin 2 1 Central Clinical Hospital of the Russian Academy of Sciences, Department of Dermatology, Mo... B Objectives b : Assessing the initial indicators of the atopic dermatitis severity of pediatric patients, the disease impact on the life quality of patients and their family members before the start of dupilumab therapy. Regarding the 60 patient-group with negative microscopy of skin scrapings, the dermoscopy exam was suggestive in 32 patients, while 28 patients presented no characteristic findings for I S. scabiei i infection on dermoscopy examination. In the 30 patients with positive microscopy of skin scraping, the dermoscopy highlighted a "delta-wing jet" sign followed by a burrow, suggestive for I S. scabiei i infection in 11 patients, while in the 37 patient-group that had not been tested, 19 patients presented a positive dermoscopy examination. [Extracted from the article]

The article describes the case of a 25-year-old White female with a transient systemic lupus erythematosus mimic caused by an acute Coxsackie B4 infection. Highlights include a lymphohistiocytic dermatitis with interphase pathology shown by anatomopathological examination, mildly elevated inflammatory markers shown by laboratory testing, and treatment with non-steroidal anti-inflammatory drugs and glucocorticoids.