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31 results on '"Ish, Jennifer"'

1. Outdoor Air Pollution Exposure and Ovarian Cancer Incidence in a United States-Wide Prospective Cohort Study

Author

Ish, Jennifer L., Chang, Che-Jung, Bookwalter, Deborah B., Jones, Rena R., M. O'Brien, Katie, Kaufman, Joel D., Sandler, Dale P., and White, Alexandra J.

Subjects
Statistics, Risk factors, Environmental aspects, Health aspects, Air pollution -- Statistics -- Health aspects, Ovarian cancer -- Statistics -- Risk factors -- Environmental aspects
Abstract

Introduction Outdoor air pollution is classified as a Group 1 carcinogen based primarily on evidence of associations with lung cancer. (1) It has increasingly been associated with a higher incidence [...]

Published
2024
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5. Susceptible windows of exposure to fine particulate matter and fetal growth trajectories in the Spanish INMA (INfancia y Medio Ambiente) birth cohort

Author

Chen, Wei-Jen, Rector, Alison M., Guxens, Monica, Iniguez, Carmen, Swartz, Michael D., Symanski, Elaine, Ibarluzea, Jesús, Ambros, Albert, Estarlich, Marisa, Lertxundi, Aitana, Riano-Galán, Isolina, Sunyer, Jordi, Fernandez-Somoano, Ana, Chauhan, Suneet P., Ish, Jennifer, and Whitworth, Kristina W.

Published
2023
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8. Exposure to per- and polyfluoroalkyl substances and breast cancer risk: a systematic review and meta-analysis of epidemiologic studies.

Author

Chang, Che-Jung, Ish, Jennifer L, Chang, Vicky C, Daniel, Meklit, Jones, Rena R, and White, Alexandra J

Subjects
*BREAST tumor risk factors, *RISK assessment, *HORMONE receptor positive breast cancer, *RESEARCH funding, *META-analysis, *DESCRIPTIVE statistics, *POSTMENOPAUSE, *SYSTEMATIC reviews, *CONFIDENCE intervals, *COMPARATIVE studies, *FLUOROCARBONS, *CELL receptors
Abstract

We synthesized the epidemiologic evidence on the associations between per- and polyfluoroalkyl substances (PFAS) exposure and breast cancer risk. Our systematic review and meta-analysis included 18 and 11 articles, respectively, covering studies up to February 2023. The summary relative risks (RRs) estimated by random-effects meta-analyses did not support an association between PFAS and overall breast cancer risk (eg, a natural log (ln)-unit increase in serum/plasma concentrations [ng/mL] for perfluorooctanoate [PFOA] RR = 0.95; 95% CI, 0.77-1.18; perfluorooctane sulfonate [PFOS] RR = 0.98; 95% CI, 0.87-1.11). However, when limiting to studies that assessed exposures prior to a breast cancer diagnosis, we observed a positive association with PFOA (a ln-unit increase, RR = 1.16; 95% CI, 0.96-1.40). We also observed some possible heterogeneous associations by tumor estrogen and progesterone receptor status among postmenopausal breast cancer cases. No meaningful changes were observed after excluding the studies with high risk of bias (Tier 3). Based on the evaluation tool developed by the National Toxicology Program, given the heterogeneity across studies and the variability in timing of exposure measurements, the epidemiologic evidence needed to determine the association between PFAS exposure and breast cancer remains inadequate. Our findings support the need for future studies with improved study designs to determine this association. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Opportunities, challenges, and future directions for simulation modeling the effects of structural racism on cancer mortality in the United States: a scoping review

Author

Jayasekera, Jinani, primary, El Kefi, Safa, additional, Fernandez, Jessica R, additional, Wojcik, Kaitlyn M, additional, Woo, Jennifer M P, additional, Ezeani, Adaora, additional, Ish, Jennifer L, additional, Bhattacharya, Manami, additional, Ogunsina, Kemi, additional, Chang, Che-Jung, additional, Cohen, Camryn M, additional, Ponce, Stephanie, additional, Kamil, Dalya, additional, Zhang, Julia, additional, Le, Randy, additional, Ramanathan, Amrita L, additional, Butera, Gisela, additional, Chapman, Christina, additional, Grant, Shakira J, additional, Lewis-Thames, Marquita W, additional, Dash, Chiranjeev, additional, Bethea, Traci N, additional, and Forde, Allana T, additional

Published
2023
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13. Susceptible windows of exposure to fine particulate matter and fetal growth trajectories in the Spanish INMA (INfancia y Medio Ambiente) birth cohort

Author

Medicina preventiva y salud pública, Prebentzio medikuntza eta osasun publikoa, Chen, Wei-Jen, Rector, Alison, Guxens, Mònica, Iñiguez, Carmen, Swartz, Michael D., Symanski, Elaine, Ibarluzea Maurolagoitia, Jesús María, Ambros, Albert, Estarlich, Marisa, Lertxundi Manterola, Aitana, Riaño Galán, Isolina, Sunyer, Jordi, Fernández Somoano, Ana, Chauhan, Suneet P. J., Ish, Jennifer, Whitworth, Kristina W., Medicina preventiva y salud pública, Prebentzio medikuntza eta osasun publikoa, Chen, Wei-Jen, Rector, Alison, Guxens, Mònica, Iñiguez, Carmen, Swartz, Michael D., Symanski, Elaine, Ibarluzea Maurolagoitia, Jesús María, Ambros, Albert, Estarlich, Marisa, Lertxundi Manterola, Aitana, Riaño Galán, Isolina, Sunyer, Jordi, Fernández Somoano, Ana, Chauhan, Suneet P. J., Ish, Jennifer, and Whitworth, Kristina W.

Abstract

While prior studies report associations between fine particulate matter (PM2.5) exposure and fetal growth, few have explored temporally refined susceptible windows of exposure.We included 2328 women from the Spanish INMA Project from 2003 to 2008. Longitudinal growth curves were constructed for each fetus using ultrasounds from 12, 20, and 34 gestational weeks. Z-scores representing growth trajectories of biparietal diameter, femur length, abdominal circumference (AC), and estimated fetal weight (EFW) during early (0-12 weeks), mid-(12-20 weeks), and late (20-34 weeks) pregnancy were calcu-lated. A spatio-temporal random forest model with back-extrapolation provided weekly PM2.5 exposure estimates for each woman during her pregnancy. Distributed lag non-linear models were implemented within the Bayesian hierarchical framework to identify susceptible windows of exposure for each outcome and cumulative effects [13cum, 95% credible interval (CrI)] were aggregated across adjacent weeks. For comparison, general linear models evaluated associations between PM2.5 averaged across multi-week periods (i.e., weeks 1-11, 12-19, and 20-33) and fetal growth, mutually adjusted for exposure during each period. Results are presented as %change in z-scores per 5 mu g/m3 in PM2.5, adjusted for covariates.Weeks 1-6 [13cum =-0.77%, 95%CrI (-1.07%,-0.47%)] were identified as a susceptible window of exposure for reduced late pregnancy EFW while weeks 29-33 were positively associated with this outcome [13cum = 0.42%, 95%CrI (0.20%, 0.64%)]. A similar pattern was observed for AC in late pregnancy. In linear regression models, PM2.5 exposure averaged across weeks 1-11 was associated with reduced late pregnancy EFW and AC; but, positive associations between PM2.5 and EFW or AC trajectories in late pregnancy were not observed.PM2.5 exposures during specific weeks may affect fetal growth differentially across pregnancy and such as-sociations may be missed by averaging exposure across multi-week

Published
2023

14. Identifying Sensitive Windows of Exposure to NO2 and Fetal Growth Trajectories in a Spanish Birth Cohort

Author

Whitworth, Kristina W., Rector, Alison, Ish, Jennifer, Chauhan, Suneet P.J., Ibarluzea, Jesús, Guxens Junyent, Mònica, Swartz, Michael D., Symanski, Elaine, Iñiguez, Carmen, Child and Adolescent Psychiatry / Psychology, and Erasmus MC other

Subjects
nitrogen dioxide, Epidemiology, air pollution, Gestational Age, ultrasonography, sensitive window, distributed lag non-linear models, Ultrasonography, Prenatal, Fetal Development, Maternal Exposure, Pregnancy, Birth Weight, Humans, Birth Cohort, Female, fetal growth, SDG 15 - Life on Land
Abstract

Background: We previously identified associations between trimester-specific NO2 exposures and reduced fetal growth in the Spanish INfancia y Medio Ambiente (INMA) project. Here, we use temporally refined exposure estimates to explore the impact of narrow (weekly) windows of exposure on fetal growth. Methods: We included 1,685 women from INMA with serial ultrasounds at 12, 20, and 34 gestational weeks. We measured biparietal diameter (BPD), femur length, and abdominal circumference (AC) and from them calculated estimated fetal weight (EFW). We calculated z-scores describing trajectories of each parameter during early (0-12 weeks), mid (12-20 weeks), and late (20-34 weeks) pregnancy, based on longitudinal growth curves from mixed-effects models. We estimated weekly NO2 exposures at each woman's residence using land-use regression models. We applied distributed lag nonlinear models to identify sensitive windows of exposure. We present effect estimates as the percentage change in fetal growth per 10 μg/m3 increase in NO2 exposure, and we calculated cumulative effect estimates by aggregating estimates across adjacent lags. Results: We identified weeks 5-12 as a sensitive window for NO2 exposure on late EFW (cumulative β = -3.0%; 95% CI = -4.1%, -1.9%). We identified weeks 6-19 as a sensitive window for late growth in BPD (cumulative β = -2.0%; 95% CI = -2.7%, -1.4%) and weeks 8-13 for AC (cumulative β = -0.68%; 95% CI = -0.97%, -0.40%). We found suggestive evidence that third trimester NO2 exposure is associated with increased AC, BPD, and EFW growth in late pregnancy. Conclusions: Our findings are consistent with the hypothesis that NO2 exposure is associated with alterations in growth of EFW, BPD, and AC dependent on the specific timing of exposure during gestation. This work was supported by grant R01ES028842 from NIH/NIEHS; grants Red INMA G03/176, CB06/02/004; FIS-FEDER: PI03/1615, PI04/1509, PI04/1112, PI04/1931, PI05/1079, PI05/1052, PI06/0867, PI06/1213, PI07/0314, PI09/02647, PI11/01007, PI11/02591, PI11/02038, PI13/1944, PI13/2032, PI14/00891, PI14/01687, PI16/1288, PI17/00663, FIS-PI18/01142 incl. FEDER funds; Miguel Servet-FEDER CP11/00178, CP15/00025, CPII16/00051, CPII18/00018, and CP16/00128 from Instituto de Salud Carlos III, grant 1999SGR 00241from Generalitat de Catalunya-CIRIT, grant FP7-ENV-2011 cod 282957 and HEALTH.2010.2.4.5-1 from the EU Commission, grant UGP-15-230, UGP-15-244, and UGP-15-249 from Generalitat Valenciana: FISABIO, grant 2005111093 from Alicia Koplowitz Foundation 2017, Department of Health of the Basque Government, grant DFG06/002 from the Provincial Government of Gipuzkoa, and annual agreements with the municipalities of the study area (Zumarraga, Urretxu, Legazpi, Azkoitia y Azpeitia y Beasain). We also acknowledge support from the Spanish Ministry of Science and Innovation and the State Research Agency through the “Centro de Excelencia Severo Ochoa 2019-2023” Program (CEX2018-000806-S), and support from the Generalitat de Catalunya through the CERCA Program.

Published
2022
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15. Correction: Maternal occupational exposure to chemicals and child cognitive function

Author

Ish, Jennifer, primary, Symanski, Elaine, additional, Gimeno Ruiz de Porras, David, additional, Casas, Maribel, additional, Delclos, George L., additional, Guxens, Mònica, additional, Ibarluzea, Jesús M., additional, Iñiguez, Carmen, additional, Lertxundi, Aitana, additional, Rebagliato, Marisa, additional, Swartz, Michael D., additional, and Whitworth, Kristina W., additional

Published
2022
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16. Maternal occupational exposures and fetal growth in a Spanish birth cohort

Author

Ish, Jennifer, Gimeno Ruiz de Porras, David, Symanski, Elaine, Ballester, Ferran, Casas, Maribel, Delclos, George L., Guxens, Mònica, Ibarluzea Maurolagoitia, Jesús María, Iñiguez, Carmen, Santa Marina Rodríguez, Loreto, Swartz, Michael D., Whitworth, Kristina W., Ish, Jennifer, Gimeno Ruiz de Porras, David, Symanski, Elaine, Ballester, Ferran, Casas, Maribel, Delclos, George L., Guxens, Mònica, Ibarluzea Maurolagoitia, Jesús María, Iñiguez, Carmen, Santa Marina Rodríguez, Loreto, Swartz, Michael D., and Whitworth, Kristina W.

Abstract

While the epidemiologic literature suggests certain maternal occupational exposures may be associated with reduced measures of size at birth, the occupational literature employing fetal biometry data to assess fetal growth is sparse. The present study examines associations between maternal occupational exposures and ultrasound-measured fetal growth. We included 1,739 singleton pregnancies from the INfancia y Medio Ambiente (INMA) project (2003-2008). At 32 weeks of pregnancy, interviewers ascertained mothers' employment status and assessed job-related physical loads, work schedules, and job strain during pregnancy. Job titles were linked to a job-exposure matrix to estimate exposure to 10 endocrine disrupting chemical (EDC) groups. We calculated z-scores from longitudinal growth curves representing trajectories from 0-12, 12-20 and 20-34 gestational weeks for abdominal circumference (AC), biparietal diameter (BPD), femur length (FL), and estimated fetal weight (EFW). Linear mixed models clustered by IMNA region (i.e., Gipuzkoa, Sabadell, Valencia) were used to examine associations between occupational exposures and fetal growth. Effect estimates are presented as percentage change in fetal growth. There was limited evidence of associations between work-related non-chemical stressors and fetal growth. We observed associations of similar magnitude between multiple EDC groups and decreased EFW trajectories during 20-34 gestational weeks (phthalates: -1.4% [-3.5, 0.6%]; alkylphenolic compounds (APCs): -1.1% [-2.3, 0.1%]; miscellaneous chemicals: -1.5% [-3.7, 0.8%]), while miscellaneous chemicals were associated with increased BPD from 12-20 weeks (2.1% [0.8, 3.5%]). Notably, 67% of women exposed to phthalates were hairdressers; 68% of women exposed to APCs worked as domestic cleaners. In conclusion, we found limited evidence that maternal occupational exposures impact fetal growth. Further research should consider the combined impact of multiple workplace exposures.

Published
2022

17. Maternal occupational exposures and fetal growth in a Spanish birth cohort

Author

Ish, Jennifer, primary, Gimeno Ruiz de Porras, David, additional, Symanski, Elaine, additional, Ballester, Ferran, additional, Casas, Maribel, additional, Delclos, George L., additional, Guxens, Mònica, additional, Ibarluzea, Jesús, additional, Iñiguez, Carmen, additional, Santa-Marina, Loreto, additional, Swartz, Michael D., additional, and Whitworth, Kristina W., additional

Published
2022
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19. Identifying Sensitive Windows of Exposure to NO2 and Fetal Growth Trajectories in a Spanish Birth Cohort.

Author

Whitworth, Kristina W., Rector, Alison, Ish, Jennifer, Chauhan, Suneet P. J., Ibarluzea, Jesus, Guxens, Monica, Swartz, Michael D., Symanski, Elaine, and Iniguez, Carmen

Abstract

Background: We previously identified associations between trimester-specific NO2 exposures and reduced fetal growth in the Spanish INfancia y Medio Ambiente (INMA) project. Here, we use temporally refined exposure estimates to explore the impact of narrow (weekly) windows of exposure on fetal growth. Methods: We included 1,685 women from INMA with serial ultrasounds at 12, 20, and 34 gestational weeks. We measured biparietal diameter (BPD), femur length, and abdominal circumference (AC) and from them calculated estimated fetal weight (EFW). We calculated z-scores describing trajectories of each parameter during early (0-12 weeks), mid (12-20 weeks), and late (20-34 weeks) pregnancy, based on longitudinal growth curves from mixed-effects models. We estimated weekly NO2 exposures at each woman's residence using land-use regression models. We applied distributed lag nonlinear models to identify sensitive windows of exposure. We present effect estimates as the percentage change in fetal growth per 10 [mu]g/m3 increase in NO2 exposure, and we calculated cumulative effect estimates by aggregating estimates across adjacent lags. Results: We identified weeks 5-12 as a sensitive window for NO2 exposure on late EFW (cumulative [beta] = -3.0%; 95% CI = -4.1%, -1.9%). We identified weeks 6-19 as a sensitive window for late growth in BPD (cumulative [beta] = -2.0%; 95% CI = -2.7%, -1.4%) and weeks 8-13 for AC (cumulative [beta] = -0.68%; 95% CI = -0.97%, -0.40%). We found suggestive evidence that third trimester NO2 exposure is associated with increased AC, BPD, and EFW growth in late pregnancy. Conclusions: Our findings are consistent with the hypothesis that NO2 exposure is associated with alterations in growth of EFW, BPD, and AC dependent on the specific timing of exposure during gestation. [ABSTRACT FROM AUTHOR]

Published
2022
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22. Maternal occupational exposures and fetal growth in a Spanish birth cohort

Author

Jennifer Ish, David Gimeno Ruiz de Porras, Elaine Symanski, Ferran Ballester, Maribel Casas, George L. Delclos, Mònica Guxens, Jesús Ibarluzea, Carmen Iñiguez, Loreto Santa-Marina, Michael D. Swartz, Kristina W. Whitworth, Child and Adolescent Psychiatry / Psychology, European Commission, Ish, Jennifer, Gimeno Ruiz de Porras, David, Symanski, Elaine, Ballester Díez, Ferran, Casas Sanahuja, Maribel, Delclos, George L., Guxens Junyent, Mònica, Ibarluzea, Jesús, Iñiguez, Carmen, Santa Marina, Loreto, Swartz, Michael D., and Whitworth, Kristina W.

Subjects
Multidisciplinary, Antigen-presenting cells, Infant, Newborn, Gestational Age, Jobs, occupational exposure, Endocrine Disruptors, Ultrasonography, Prenatal, infant, newborn, Fetal Development, Phthalates, Psychological stress, Maternal Exposure, Pregnancy, maternal exposure, Occupational Exposure, Birth, Cohort studies, Birth Weight, Humans, Birth Cohort, Female, pregnancy, Chemical disruption, ultrasonography, prenatal
Abstract

While the epidemiologic literature suggests certain maternal occupational exposures may be associated with reduced measures of size at birth, the occupational literature employing fetal biometry data to assess fetal growth is sparse. The present study examines associations between maternal occupational exposures and ultrasound-measured fetal growth. We included 1,739 singleton pregnancies from the INfancia y Medio Ambiente (INMA) project (2003-2008). At 32 weeks of pregnancy, interviewers ascertained mothers' employment status and assessed job-related physical loads, work schedules, and job strain during pregnancy. Job titles were linked to a job-exposure matrix to estimate exposure to 10 endocrine disrupting chemical (EDC) groups. We calculated z-scores from longitudinal growth curves representing trajectories from 0-12, 12-20 and 20-34 gestational weeks for abdominal circumference (AC), biparietal diameter (BPD), femur length (FL), and estimated fetal weight (EFW). Linear mixed models clustered by IMNA region (i.e., Gipuzkoa, Sabadell, Valencia) were used to examine associations between occupational exposures and fetal growth. Effect estimates are presented as percentage change in fetal growth. There was limited evidence of associations between work-related non-chemical stressors and fetal growth. We observed associations of similar magnitude between multiple EDC groups and decreased EFW trajectories during 20-34 gestational weeks (phthalates: -1.4% [-3.5, 0.6%]; alkylphenolic compounds (APCs): -1.1% [-2.3, 0.1%]; miscellaneous chemicals: -1.5% [-3.7, 0.8%]), while miscellaneous chemicals were associated with increased BPD from 12-20 weeks (2.1% [0.8, 3.5%]). Notably, 67% of women exposed to phthalates were hairdressers; 68% of women exposed to APCs worked as domestic cleaners. In conclusion, we found limited evidence that maternal occupational exposures impact fetal growth. Further research should consider the combined impact of multiple workplace exposures. This work was supported by grants from the National Institutes of Health/National Institute of Environmental Health Sciences (R01ES028842, PI: KWW), Instituto de Salud Carlos III (Red INMA G03/176, CB06/02/0041; FIS-FEDER: PI03/1615, PI04/1509, PI04/1112, PI04/1931, PI05/1079, PI05/1052, PI06/0867, PI06/1213, PI07/0314, PI09/02647, PI11/01007, PI11/02591, PI11/02038, PI13/1944, PI13/2032, PI14/00891, PI14/01687, PI16/1288, PI17/00663, FIS-PI18/01142 incl. FEDER funds; Miguel Servet-FEDER CP11/00178, CP15/00025, CPII16/00051, CPII18/00018, and CP16/00128), Generalitat de Catalunya-CIRIT 1999SGR 00241, EU Commission (FP7-ENV-2011 cod 282957 and HEALTH.2010.2.4.5-1), Generalitat Valenciana: FISABIO (UGP 15-230, UGP-15-244, and UGP-15-249) and Conselleria d’Educació AICO/2020/285, and Alicia Koplowitz Foundation 2017, Department of Health of the Basque Government (2005111093), Provincial Government of Gipuzkoa (DFG06/002), and annual agreements with the municipalities of the study area (Zumarraga, Urretxu, Legazpi, Azkoitia y Azpeitia y Beasain). We also acknowledge support from the Spanish Ministry of Science and Innovation and the State Research Agency through the “Centro de Excelencia Severo Ochoa 2019-2023” Program (CEX2018-000806-S), and support from the Generalitat de Catalunya through the CERCA Program. JI, DGRdP, and GLD were partly supported by the Southwest Center for Occupational and Environmental Health (SWCOEH), the Centers for Disease Control and Prevention (CDC) National Institute for Occupational Safety and Health (NIOSH) Education and Research Center (T42OH008421) at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health. KWW and ES were supported in part by the by the Gulf Coast Center for Precision Environmental Health (GC-CPEH) at Baylor College of Medicine (P30ES030285). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Published
2021

25. NJ NATIVE MARK KAMINE CREATES SOME OF THE SHOWS YOU TALK ABOUT

Subjects
General interest, News, opinion and commentary
Abstract

Byline: Cindy Schweich Handler Mark Kamine's work takes him to a lot of high-profile locations, including Wailea in Maui, Taormina in Sicily, and Kearny in Hudson County. While Kearny isn't [...]

Published
2024

26. A Shadow's Bliss : A Novel of Georgian England

Author

Patricia Veryan and Patricia Veryan

Abstract

She had dreamed of that magical experience called falling in love. And, dreaming, she had conjured up a dashing and handsome gentleman...A far cry from Crazy Jack, a penniless and nameless vagrant, haunted by disgrace and the shadow of some terrible tragedy. Dreams are all that the graceful Jennifer Britewell has had of love and marriage since a childhood accident left her barren. Now, try as she might, the generous lady cannot bring herself to believe the town gossip about'Crazy Jack.'It would be beneath her to consider him anything but a servant. But when he allows her to see traces of his honesty, intelligence, and gallantry, all warnings of her possible disgrace fade into the mists of Cornwall...

Published
2015

27. Event Brief of Q4 2009 M&T Bank Corporation Earnings Conference Call - Final

Subjects
Banks (Finance) -- Reports, Financial markets -- Reports, Real property -- Reports, Business
Abstract

PARTICIPANTS . Don MacLeod, M&T Bank Corporation, VP of IR . Rene Jones, M&T Bank Corporation, EVP & CFO . Steven Alexopoulos, JPMorgan Chase & Co., Analyst . Ken Zerbe, [...]

Published
2010

28. Q4 2009 M&T Bank Corporation Earnings Conference Call - Final

Subjects
Banks (Finance), Business
Abstract

OPERATOR: Good afternoon. I'll be your conference operator today. At this time, I would like to welcome everyone to the M&T Bank fourth quarter 2009 earnings conference call. All lines [...]

Published
2010

30. A test of love for labor and management

Author

Brantley, Ben

Subjects
The Pajama Game (Play) -- Theater reviews, Theater -- Theater reviews
Abstract

She's a sassy, grown-up tomboy with the coltishness of a girl and the heart of a woman. He's a handsome man with a handsome voice and a virile, straight-spined strut. […]

Published
2002

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