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Your search keyword '"ISAAC, DEBRA L."' showing total 28 results
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28 results on '"ISAAC, DEBRA L."'

1. Feasibility of Sildenafil for the Prevention of Right Heart Failure Following Continuous-Flow Left Ventricular Assist Device Implantation: The REVAD Trial

Author

Fine, Nowell M., primary, Litwin, Owen, additional, Kent, William D.T., additional, Holloway, Daniel D., additional, Roy, Jill, additional, Miller, Robert J.H., additional, Chih, Sharon, additional, Davey, Ryan A., additional, Isaac, Debra L., additional, Sharma, Nakul, additional, Lyons, Kristin J., additional, and Howlett, Jonathan G., additional

Published
2023
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6. The 2014 Canadian Cardiovascular Society Heart Failure Management Guidelines Focus Update: Anemia, Biomarkers, and Recent Therapeutic Trial Implications

Author

Moe, Gordon W., Ezekowitz, Justin A., O'Meara, Eileen, Lepage, Serge, Howlett, Jonathan G., Fremes, Steve, Al-Hesayen, Abdul, Heckman, George A., Abrams, Howard, Ducharme, Anique, Estrella-Holder, Estrellita, Grzeslo, Adam, Harkness, Karen, Koshman, Sheri L., McDonald, Michael, McKelvie, Robert, Rajda, Miroslaw, Rao, Vivek, Swiggum, Elizabeth, Virani, Sean, Zieroth, Shelley, Arnold, J.Malcolm O., Ashton, Tom, D'Astous, Michel, Chan, Michael, De, Sabe, Dorian, Paul, Giannetti, Nadia, Haddad, Haissam, Isaac, Debra L., Kouz, Simon, Leblanc, Marie-Hélène, Liu, Peter, Ross, Heather J., Sussex, Bruce, and White, Michel

Published
2015
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7. The 2013 Canadian Cardiovascular Society Heart Failure Management Guidelines Update: Focus on Rehabilitation and Exercise and Surgical Coronary Revascularization

Author

Moe, Gordon W., Ezekowitz, Justin A., O'Meara, Eileen, Howlett, Jonathan G., Fremes, Steve E., Al-Hesayen, Abdul, Heckman, George A., Ducharme, Anique, Estrella-Holder, Estrellita, Grzeslo, Adam, Harkness, Karen, Lepage, Serge, McDonald, Michael, McKelvie, Robert S., Nigam, Anil, Rajda, Miroslaw, Rao, Vivek, Swiggum, Elizabeth, Virani, Sean, Van Le, Vy, Zieroth, Shelley, Arnold, J. Malcolm O., Ashton, Tom, D'Astous, Michel, Dorian, Paul, Giannetti, Nadia, Haddad, Haissam, Isaac, Debra L., Kouz, Simon, Leblanc, Marie-Hélène, Liu, Peter, Ross, Heather J., Sussex, Bruce, and White, Michel

Published
2014
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8. The 2012 Canadian Cardiovascular Society Heart Failure Management Guidelines Update: Focus on Acute and Chronic Heart Failure

Author

McKelvie, Robert S., Moe, Gordon W., Ezekowitz, Justin A., Heckman, George A., Costigan, Jeannine, Ducharme, Anique, Estrella-Holder, Estrellita, Giannetti, Nadia, Grzeslo, Adam, Harkness, Karen, Howlett, Jonathan G., Kouz, Simon, Leblanc, Kori, Mann, Elizabeth, Nigam, Anil, O'Meara, Eileen, Rajda, Miroslaw, Steinhart, Brian, Swiggum, Elizabeth, Le, Vy Van, Zieroth, Shelley, Arnold, J. Malcolm O., Ashton, Tom, D'Astous, Michel, Dorian, Paul, Haddad, Haissam, Isaac, Debra L., Leblanc, Marie-Hélène, Liu, Peter, Rao, Vivek, Ross, Heather J., and Sussex, Bruce

Published
2013
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9. The Veins and Ventricular Preload

Author

Tyberg, John V., Wang, Steven Y., Scott-Douglas, Nairne W., Robinson, Vincent J. B., Chihara, Eiichi, Semeniuk, Lisa M., Isaac, Debra L., Belenkie, Israel, Manyari, Dante E., Maruyama, Yukio, editor, Hori, Masatsugu, editor, and Janicki, Joseph S., editor

Published
1997
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10. The 2011 Canadian Cardiovascular Society Heart Failure Management Guidelines Update: Focus on Sleep Apnea, Renal Dysfunction, Mechanical Circulatory Support, and Palliative Care

Author

McKelvie, Robert S., Moe, Gordon W., Cheung, Anson, Costigan, Jeannine, Ducharme, Anique, Estrella-Holder, Estrellita, Ezekowitz, Justin A., Floras, John, Giannetti, Nadia, Grzeslo, Adam, Harkness, Karen, Heckman, George A., Howlett, Jonathan G., Kouz, Simon, Leblanc, Kori, Mann, Elizabeth, O'Meara, Eileen, Rajda, Miroslav, Rao, Vivek, Simon, Jessica, Swiggum, Elizabeth, Zieroth, Shelley, Arnold, J. Malcolm O., Ashton, Tom, D'Astous, Michel, Dorian, Paul, Haddad, Haissam, Isaac, Debra L., Leblanc, Marie-Hélène, Liu, Peter, Sussex, Bruce, and Ross, Heather J.

Published
2011
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11. Extensive environmental contamination and prolonged severe acute respiratory coronavirus-2 (SARS CoV-2) viability in immunosuppressed recent heart transplant recipients with clinical and virologic benefit with remdesivir

Author

Rajakumar, Irina, primary, Isaac, Debra L., additional, Fine, Nowell M., additional, Clarke, Brian, additional, Ward, Linda P., additional, Malott, Rebecca J., additional, Pabbaraju, Kanti, additional, Gill, Kara, additional, Berenger, Byron M., additional, Lin, Yi-Chan, additional, Evans, David H., additional, and Conly, John M., additional

Published
2021
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13. Acute Precipitants of Congestive Heart Failure Exacerbations

Author

Tsuyuki, Ross T., McKelvie, Robert S., Arnold, J. Malcolm O., Avezum, Álvaro, Jr, Barretto, Antônio C. P., Carvalho, Antonio C. C., Isaac, Debra L., Kitching, Allan D., Piegas, Leopoldo S., Teo, Koon K., and Yusuf, Salim

Published
2001

23. A sensitive approach

Author

Chih, Sharon, primary, Ross, Heather J., additional, Tinckam, Kathryn, additional, McDonald, Michael A., additional, and Isaac, Debra L., additional

Published
2012
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26. Assessment and Treatment of Thyroid Function in Heart Failure Clinics - Incidence of Abnormal Thyroid Function and Impact on Heart Failure Decompensation.

Author

Shafran, Daniel M. and Isaac, Debra L.

Subjects
*THYROID diseases, *HEART diseases, *HEART failure, *THYROID gland function tests, *ENDOCRINE function tests, *CLINICS
Abstract

Abnormal thyroid function (TF) is associated with cardiac dysfunction and may result in decompensation in patients with pre-existing heart failure (HF). International HF guidelines recommend routine assessment and treatment of TF. It is unclear to what extent TF is monitored in Canadian clinics, what the incidence of abnormal TF is in HF patients, and how TF abnormalities impact outcomes. METHODS: Retrospective review was performed for all patients managed at 3 hospital-based HF clinics in Calgary from November 2010 to January 2011. RESULTS: Charts of 773 patients were reviewed. Of these, 719 (93.0%) patients had some documentation of Thyroid Function Tests (TFTs); 592 (76.6%) had TFTs in the previous 12 months, and 54 (7.0%) had no record of TFTs. 21.3% (165) of patients had documented abnormal TF. Of 658 patients with normal TFTs (treated or not), 30.2% (199) decompensated compared to 41.0% (25) with abnormal TFTs (P=0.1109). Decompensation rates in patients with normal TFTs versus patients whose TFTs were abnormal or never measured were 30.2% (199) and 47.8% (55) respectively (P=0.0003). CONCLUSIONS: TF abnormalities are common in Calgary HF Clinic patients. The rate of HF decompensation is significantly lower in patients with normal TFTs than in those with unmeasured or abnormal TFTs. Further investigation is required to further evaluate the role of assessment and treatment of TF in reducing HF decompensation. [ABSTRACT FROM AUTHOR]

Published
2012

28. Host-microbe interactions in the pathogenesis and clinical course of sarcoidosis.

Author

Inaoka, Pleiades T., Shono, Masato, Kamada, Mishio, and Espinoza, J. Luis

Subjects
SARCOIDOSIS, ETIOLOGY of diseases, HUMAN microbiota, THERAPEUTICS, LYMPH nodes, IMMUNE response
Abstract

Sarcoidosis is a rare inflammatory disease characterized by the development of granulomas in various organs, especially in the lungs and lymph nodes. Clinics of the disease largely depends on the organ involved and may range from mild symptoms to life threatening manifestations. Over the last two decades, significant advances in the diagnosis, clinical assessment and treatment of sarcoidosis have been achieved, however, the precise etiology of this disease remains unknown. Current evidence suggests that, in genetically predisposed individuals, an excessive immune response to unknown antigen/s is crucial for the development of sarcoidosis. Epidemiological and microbiological studies suggest that, at least in a fraction of patients, microbes or their products may trigger the immune response leading to sarcoid granuloma formation. In this article, we discuss the scientific evidence on the interaction of microbes with immune cells that may be implicated in the immunopathogenesis of sarcoidosis, and highlight recent studies exploring potential implications of human microbiota in the pathogenesis and the clinical course of sarcoidosis. [ABSTRACT FROM AUTHOR]

Published
2019
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