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3. Breaking barriers: holistic assessment of ability to work in patients with sarcoidosis

Author

Drent, Marjolein, Russell, Anne-Marie, Saketkoo, Lesley Ann, Spagnolo, Paolo, Veltkamp, Marcel, Wells, Athol U, Goh, Nicole, Holland, Anne, Hochreiter, Johann, Kock, Selene, Verheyen, Karolien, Verbraecken, Johan, Cantin, André, Gillson, Ashley, Hambly, Nathan, Kolb, Martin, Bendstrup, Elisabeth, Leistiko, Anna, Møller, Janne, Kaarteenaho, Riitta, Crestani, Bruno, Israël-Biet, Dominique, Cohen Aubart, Fleur, Nunes, Hilario, Valeyre, Dominique, Bonella, Francesco, Buschulte, Katharina, Costabel, Ulrich, Kortsen, Peter, Kreuter, Michael, Luedike, Peter, Quadder, Bernd, Braune, Renate, Skowasch, Dirk, Antoniou, Katerina, Bouros, Demosthenes, Gogali, Athena, Margaritopoulos, George A., Papakosta, Despoina, Papiris, Spyros A, Manali, Effrosyni D, Tzouvelekis, Argyris, Tzilas, Vasilios, Agrawal, Aditya, Kashyap, Surender, Tyagi, Vijay Narain, Unnati, Desai, Abedini, Atefeh, Phelan, Sean, Bargagli, Elena, Cinetto, Francesco, Confalonieri, Marco, Confalonieri, Paola, Harari, Sergio, Luppi, Fabrizio, Martone, Filippo, Palmieri, Anna, Rottoli, Paola, Salton, Francesco, Scarpa, Ricardo, Tana, Claudio, Tomassetti, Sara, Azuma, Arata, Inui, Naoki, Nakamura, Yutaro, Inoue, Yoshikazu, Tanino, Yoshinori, Muhammad, Noorul Afidza, van Beek, Frouke, den Boer, Lenze, Boomars, Karin, Bresser, Paul, Claessen, Laura, Elfferich, Marjon, Erckens, Roel, van Helmondt, Sanne, Karakaya, Bekir, Grutters, Jan C., Hoitsma, Elske, Illy, Károly, Jansen, Tim L, Kahlmann, Vivienne, Knoet, Chris, Korenromp, Ingrid, Lenssen, Ton, Maassen vd Brinkdrs, Karen, Mager, Johannes Jurgen, Marcellis, Rik, Miedema, Jelle, Möller, Trudeke, Moonen, Linda A.A., Moor, Karen, Mostard, Rémy L.M., Nienhuis, Willemien, Nossent, Esther, Paulus, Michelle, Ponds, Rudolf, Nossent, George, Quanjel, Marian, Rottenberg, Felix, van de Sande, Jonathan S.O., Segers, Ruud, Soechitram, Shalini D., van Staa, AnneLoes, Strookappe, Bert, Swaans, Martin, van den Toorn, Leon, van de Ven, Marjo J.T., Voortman, Mareye, Vorselaars, Adriane Dore Marie, Vente, Lenneke, Wijnen, Petal A., Wijsenbeek, Marlies, De Vries, Jolanda, van Zanten, Arthur, Durheim, Michael, Rasch-Halvorsen, Øystein, Tøndell, Anders, Dubaniewicz, Anna, Piotrowski, Wojciech, Roter, Bartlomiej, Robalo Cordeiro, Carlos, Alfaro, Tiago, Strambu, Irina, Vizel, Alexander, Cano, Rafael, Balcells, Eva, Castillo, Diego, Francesqui, Joel, Mañá, Juan, Molina, Maria, Ojanguren, Inigo, Rodriguez Portal, Jose Antonio, Sellares, Jacobo, Arkema, Elizabeth, Darlington, Pernilla, Eldhagen, Per, Elfström, Katinka, Grunewald, Johan, Kullberg, Susanna, Rivera, Natalia V, Rossides, Marios, Werner, Joanna, Dincer, Irem, Koç, Gülcan, Yucesan, Canan, Ozdemir Kumbasar, Ozlem, Birring, Surinder, Boyd, Jeanette, Casimo, Leo, Huntley, Christopher, Kouranos, Vasileios, Newton, Jaqui, Spencer, Lisa, Spears, Mark, Barreras, Paula, Cozier, Yvette, Crouser, Elliott, Harper, Logan, James, W. Ennis, Maier, Lisa, Liao, Shu-Yi, Morgenthau, Adam, Obi, Ogugua Ndili, Patel, Divya, Rivera, Frank, Rossman, Milton D., Sharp, Michelle, Sharma, Maggie, Schupp, Jonas C., Stern, Barney J., Sweiss, Nadera, Tavee, Jinny, Zank, Daniel, Gumeniuk, Galyna, Gavrysyuk, Volodymyr, and Merenkova, Levgeniia

Published
2024
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4. Reliability parameters of the Timed 25-Foot-Walk (T25FW) in patients with Multiple Sclerosis: Lower walking speed is associated with greater Smallest Detectable Change

Author

Revalidatiegeneeskunde Onderzoek, Oosterveer, Daniëlla M., Wouda, Natasja C., Volker, Gerard, van den Berg, Christel, Terluin, Berend, Hoitsma, Elske, Revalidatiegeneeskunde Onderzoek, Oosterveer, Daniëlla M., Wouda, Natasja C., Volker, Gerard, van den Berg, Christel, Terluin, Berend, and Hoitsma, Elske

Published
2024

5. Cognitive functioning as a predictor of employment status in relapsing-remitting multiple sclerosis: a 2-year longitudinal study

Author

van Gorp, Dennis A.M., van der Hiele, Karin, Heerings, Marco A.P., Jongen, Peter J., van der Klink, Jac J.L., Reneman, Michiel F., Arnoldus, Edo P.J., Beenakker, Ernesto A.C., van Eijk, Jeroen J.J., Frequin, Stephan T.F.M., de Gans, Koen, Hoitsma, Elske, Mostert, Jop P., Verhagen, Wim I.M., Zemel, Désirée, Visser, Leo H., and Middelkoop, Huub A.M.

Published
2019
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6. Breaking barriers: holistic assessment of ability to work in patients with sarcoidosis

Author

Goh, Nicole, Holland, Anne, Hochreiter, Johann, Kock, Selene, Verheyen, Karolien, Verbraecken, Johan, Cantin, André, Gillson, Ashley, Hambly, Nathan, Kolb, Martin, Bendstrup, Elisabeth, Leistiko, Anna, Møller, Janne, Kaarteenaho, Riitta, Crestani, Bruno, Israël-Biet, Dominique, Cohen Aubart, Fleur, Nunes, Hilario, Valeyre, Dominique, Bonella, Francesco, Buschulte, Katharina, Costabel, Ulrich, Kortsen, Peter, Kreuter, Michael, Luedike, Peter, Quadder, Bernd, Braune, Renate, Skowasch, Dirk, Antoniou, Katerina, Bouros, Demosthenes, Gogali, Athena, Margaritopoulos, George A., Papakosta, Despoina, Papiris, Spyros A, Manali, Effrosyni D, Tzouvelekis, Argyris, Tzilas, Vasilios, Agrawal, Aditya, Kashyap, Surender, Tyagi, Vijay Narain, Unnati, Desai, Abedini, Atefeh, Phelan, Sean, Bargagli, Elena, Cinetto, Francesco, Confalonieri, Marco, Confalonieri, Paola, Harari, Sergio, Luppi, Fabrizio, Martone, Filippo, Palmieri, Anna, Rottoli, Paola, Salton, Francesco, Scarpa, Ricardo, Tana, Claudio, Tomassetti, Sara, Azuma, Arata, Inui, Naoki, Nakamura, Yutaro, Inoue, Yoshikazu, Tanino, Yoshinori, Muhammad, Noorul Afidza, van Beek, Frouke, den Boer, Lenze, Boomars, Karin, Bresser, Paul, Claessen, Laura, Elfferich, Marjon, Erckens, Roel, van Helmondt, Sanne, Karakaya, Bekir, Grutters, Jan C., Hoitsma, Elske, Illy, Károly, Jansen, Tim L, Kahlmann, Vivienne, Knoet, Chris, Korenromp, Ingrid, Lenssen, Ton, Maassen vd Brinkdrs, Karen, Mager, Johannes Jurgen, Marcellis, Rik, Miedema, Jelle, Möller, Trudeke, Moonen, Linda A.A., Moor, Karen, Mostard, Rémy L.M., Nienhuis, Willemien, Nossent, Esther, Paulus, Michelle, Ponds, Rudolf, Nossent, George, Quanjel, Marian, Rottenberg, Felix, van de Sande, Jonathan S.O., Segers, Ruud, Soechitram, Shalini D., van Staa, AnneLoes, Strookappe, Bert, Swaans, Martin, van den Toorn, Leon, van de Ven, Marjo J.T., Voortman, Mareye, Vorselaars, Adriane Dore Marie, Vente, Lenneke, Wijnen, Petal A., Wijsenbeek, Marlies, De Vries, Jolanda, van Zanten, Arthur, Durheim, Michael, Rasch-Halvorsen, Øystein, Tøndell, Anders, Dubaniewicz, Anna, Piotrowski, Wojciech, Roter, Bartlomiej, Robalo Cordeiro, Carlos, Alfaro, Tiago, Strambu, Irina, Vizel, Alexander, Cano, Rafael, Balcells, Eva, Castillo, Diego, Francesqui, Joel, Mañá, Juan, Molina, Maria, Ojanguren, Inigo, Rodriguez Portal, Jose Antonio, Sellares, Jacobo, Arkema, Elizabeth, Darlington, Pernilla, Eldhagen, Per, Elfström, Katinka, Grunewald, Johan, Kullberg, Susanna, Rivera, Natalia V, Rossides, Marios, Werner, Joanna, Dincer, Irem, Koç, Gülcan, Yucesan, Canan, Ozdemir Kumbasar, Ozlem, Birring, Surinder, Boyd, Jeanette, Casimo, Leo, Huntley, Christopher, Kouranos, Vasileios, Newton, Jaqui, Spencer, Lisa, Spears, Mark, Barreras, Paula, Cozier, Yvette, Crouser, Elliott, Harper, Logan, James, W. Ennis, Maier, Lisa, Liao, Shu-Yi, Morgenthau, Adam, Obi, Ogugua Ndili, Patel, Divya, Rivera, Frank, Rossman, Milton D., Sharp, Michelle, Sharma, Maggie, Schupp, Jonas C., Stern, Barney J., Sweiss, Nadera, Tavee, Jinny, Zank, Daniel, Gumeniuk, Galyna, Gavrysyuk, Volodymyr, Merenkova, Levgeniia, Drent, Marjolein, Russell, Anne-Marie, Saketkoo, Lesley Ann, Spagnolo, Paolo, Veltkamp, Marcel, and Wells, Athol U

Published
2024
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7. Prospective trial of natalizumab personalised extended interval dosing by therapeutic drug monitoring in relapsing-remitting multiple sclerosis (NEXT- MS).

Author

Toorop, Alyssa A., van Lierop, Zoë Y. G. J., Gelissen, Liza M. Y., Hoitsma, Elske, Zeinstra, Esther M. P. E., van Rooij, Luuk C., van Munster, Caspar E. P., Vennegoor, Anke, Mostert, Jop P., Wokke, Beatrijs H. A., Kalkers, Nynke F., Hoogervorst, Erwin L. J., van Eijk, Jeroen J. J., Roosendaal, Christiaan M., Kragt, Jolijn J., Eurelings, Marijke, van Genugten, Jessie, Nielsen, Jessica, Sinnige, L. G. F., and Kloosterziel, Mark E.

Subjects
NATALIZUMAB, DRUG monitoring, JOHN Cunningham virus, MULTIPLE sclerosis, DISEASE relapse, PROGRESSIVE multifocal leukoencephalopathy, COVID-19 pandemic
Published
2024
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8. Prospective trial of natalizumab personalised extended interval dosing by therapeutic drug monitoring in relapsing-remitting multiple sclerosis (NEXT-MS)

Author

Toorop, Alyssa A, primary, van Lierop, Zoë YGJ, additional, Gelissen, Liza MY, additional, Hoitsma, Elske, additional, Zeinstra, Esther MPE, additional, van Rooij, Luuk C, additional, van Munster, Caspar EP, additional, Vennegoor, Anke, additional, Mostert, Jop P, additional, Wokke, Beatrijs HA, additional, Kalkers, Nynke F, additional, Hoogervorst, Erwin LJ, additional, van Eijk, Jeroen JJ, additional, Roosendaal, Christiaan M, additional, Kragt, Jolijn J, additional, Eurelings, Marijke, additional, van Genugten, Jessie, additional, Nielsen, Jessica, additional, Sinnige, LGF, additional, Kloosterziel, Mark E, additional, Arnoldus, Edo PJ, additional, van Dijk, Gert W, additional, Bouvy, Willem H, additional, Wessels, Mark HJ, additional, Boonkamp, Lynn, additional, Strijbis, Eva MM, additional, van Oosten, Bob W, additional, De Jong, Brigit A, additional, Lissenberg-Witte, Birgit I, additional, Barkhof, Frederik, additional, Moraal, Bastiaan, additional, Teunissen, Charlotte E, additional, Rispens, Theo, additional, Uitdehaag, Bernard MJ, additional, Killestein, Joep, additional, and van Kempen, Zoé LE, additional

Published
2023
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10. Decrease of natalizumab drug levels after switching from intravenous to subcutaneous administration in patients with multiple sclerosis

Author

Toorop, Alyssa A, primary, van Kempen, Zoé L E, additional, Steenhuis, Maurice, additional, Nielsen, Jessica, additional, Sinnige, L G F, additional, van Dijk, Gert, additional, Roosendaal, Christiaan M, additional, Arnoldus, Edo P J, additional, Hoitsma, Elske, additional, Lissenberg-Witte, Birgit I, additional, de Jong, Brigit A, additional, Oosten, Bob W van, additional, Strijbis, Eva M M, additional, Uitdehaag, Bernard M J, additional, Rispens, Theo, additional, and Killestein, Joep, additional

Published
2023
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14. Multiple Sclerosis Work Difficulties Questionnaire--Dutch Version

Author

van Egmond, Elianne, primary, van Gorp, Dennis, additional, Honan, Cynthia, additional, Heerings, Marco, additional, Jongen, Peter, additional, van der Klink, Jac, additional, Reneman, Michiel, additional, Beenakker, Ernesto, additional, Frequin, Stephan, additional, de Gans, Koen, additional, Hengstman, Gerald, additional, Hoitsma, Elske, additional, Mostert, Jop, additional, Verhagen, Wim, additional, Zemel, Désirée, additional, Middelkoop, Huub, additional, Visser, Leo, additional, and van der Hiele, Karin, additional

Published
2021
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18. A Dutch validation study of the Multiple Sclerosis Work Difficulties Questionnaire in relapsing remitting multiple sclerosis.

Author

van Egmond, Elianne, van Gorp, Dennis, Honan, Cynthia, Heerings, Marco, Jongen, Peter, van der Klink, Jac, Reneman, Michiel, Beenakker, Ernesto, Frequin, Stephan, de Gans, Koen, Hengstman, Gerald, Hoitsma, Elske, Mostert, Jop, Verhagen, Wim, Zemel, Désirée, Middelkoop, Huub, Visser, Leo, and van der Hiele, Karin

Subjects
MULTIPLE sclerosis, STATISTICS, KRUSKAL-Wallis Test, WORK environment, LABOR productivity, RESEARCH evaluation, CONFIDENCE intervals, RESEARCH methodology evaluation, RESEARCH methodology, SELF-evaluation, FUNCTIONAL status, QUALITY of work life, AGE distribution, CASE-control method, MANN Whitney U Test, COGNITION, PSYCHOMETRICS, PSYCHOLOGICAL tests, MULTITRAIT multimethod techniques, SEX distribution, QUESTIONNAIRES, EMPLOYMENT, FACTOR analysis, SCALE analysis (Psychology), QUALITY of life, CHI-squared test, DESCRIPTIVE statistics, RESEARCH funding, LOGISTIC regression analysis, PREDICTIVE validity, STATISTICAL correlation, DATA analysis, FATIGUE (Physiology), DATA analysis software, EDUCATIONAL attainment
Abstract

The current study aimed to evaluate the psychometric properties of the Dutch version of the Multiple Sclerosis Work Difficulties Questionnaire-23 (MSWDQ-23). Two hundred and thirty-nine employed persons with multiple sclerosis (MS) and 59 healthy controls completed the MSWDQ-23. To verify the factor structure, a confirmatory factor analysis was conducted. To assess construct validity, the MSWDQ-23 scores were correlated to measures of physical disability, fatigue, cognitive and neuropsychiatric problems, depression, health-related quality of life, and work-related variables. MSWDQ-23 scores were compared within different age groups, gender, education levels, and job types. Predictive validity was assessed using a logistic regression analysis to predict a deterioration in employment status after one year based on MSWDQ-23 scores. The internal consistency of the MSWDQ-23 was acceptable (α = 0.913, 95% CI = 0.897–0.928) and the results indicated a fair fit. The MSWDQ-23 showed acceptable construct validity, confirming 94% of the hypotheses. The total scale and the psychological/cognitive subscale were able to predict a deterioration in employment status after one year (χ2(1)=18.164, p < 0.001). The Dutch version of the MSWDQ-23 is a valid and internally consistent instrument to measure self-reported work difficulties in persons with MS. The Dutch version of the 23-item Multiple Sclerosis Work Difficulties Questionnaire (MSWDQ-23) is a reliable and valid tool to measure self-reported work difficulties in people with multiple sclerosis (MS). More psychological and cognitive work difficulties are predictive of a deteriorated employment status after one year. The MSWDQ-23 is a helpful tool for researchers and (occupational) health professionals to identify current work difficulties in persons with MS and identify persons at risk for a deterioration in employment one year later. [ABSTRACT FROM AUTHOR]

Published
2021
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19. Determination Of The Smallest Detectable Change (Sdc) And The Minimal Important Difference (Mid) For The Small Fiber Neuropathy Screening List (Sfnsl) In Sarcoidosis

Author

Voortman, Mareye, Beekman, Emmylou, Drent, Marjolein, Hoitsma, Elske, De Vries, Jolanda, Promovendi PHPC, RS: CAPHRI - R3 - Functioning, Participating and Rehabilitation, and Faculteit FHML Centraal

Subjects
Pulmonary and Respiratory Medicine, SYMPTOMS, Sarcoidosis, small fiber neuropathy, FATIGUE ASSESSMENT SCALE, DIAGNOSTIC-CRITERIA, QUESTIONNAIRE, smallest detectable change, VALIDATION, RESPONSIVENESS, minimal important difference (MID), Smallest detectable change, Internal Medicine, Immunology and Allergy, sarcoidosis, HEALTH-STATUS, neurosarcoidosis, Small fiber neuropathy screening list (SFNSL), ARA 290, smallest detectable change (SDC), minimal important difference, Minimal important difference, Small fiber neuropathy, METHODOLOGICAL QUALITY, SYSTEM, small fiber neuropathy screening list (SFNSL)
Abstract

Background: Previous studies found that 40-60% of the sarcoidosis patients suffer from small fiber neuropathy (SFN), substantially affecting quality of life. SFN is difficult to diagnose, as a gold standard is still lacking. The need for an easily administered screening instrument to identify sarcoidosis-associated SFN symptoms led to the development of the SFN Screening List (SFNSL). The usefulness of any questionnaire in clinical management and research trials depends on its interpretability. Obtaining a clinically relevant change score on a questionnaire requires that the smallest detectable change (SDC) and minimal important difference (MID) are known. Objectives: The aim of this study was to determine the SDC and MID for the SFNSL in patients with sarcoidosis. Methods: Patients with neurosarcoidosis and/or sarcoidosis-associated SFN symptoms (N=138) included in the online Dutch Neurosarcoidosis Registry participated in a prospective, longitudinal study. Anchor-based and distribution-based methods were used to estimate the MID and SDC, respectively. Results: The SFNSL was completed both at baseline and at 6-months' follow-up by 89/138 patients. A marginal ROC curve (0.6) indicated cut-off values of 3.5 points, with 73% sensitivity and 49% specificity for change. The SDC was 11.8 points. Conclusions: The MID on the SFNSL is 3.5 points for a clinically relevant change over a 6-month period. The MID can be used in the follow-up and management of SFN-associated symptoms in patients with sarcoidosis, though with some caution as the SDC was found to be higher.

Published
2018

20. A Dutch validation study of the Multiple Sclerosis Work Difficulties Questionnaire in relapsing remitting multiple sclerosis

Author

van Egmond, Elianne, primary, van Gorp, Dennis, additional, Honan, Cynthia, additional, Heerings, Marco, additional, Jongen, Peter, additional, van der Klink, Jac, additional, Reneman, Michiel, additional, Beenakker, Ernesto, additional, Frequin, Stephan, additional, de Gans, Koen, additional, Hengstman, Gerald, additional, Hoitsma, Elske, additional, Mostert, Jop, additional, Verhagen, Wim, additional, Zemel, Désirée, additional, Middelkoop, Huub, additional, Visser, Leo, additional, and van der Hiele, Karin, additional

Published
2019
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23. VALIDATION OF THE KING'S SARCOIDOSIS QUESTIONNAIRE (KSQ) IN A DUTCH SARCOIDOSIS POPULATION

Author

van Manen, Mirjam J. G., van Manen, Mirjam J. G., Wapenaar, Monique, Strookappe, Bert, Drent, Marjolein, Elfferich, Marjon, de Vries, Jolanda, Gosker, Harry R., Birring, Surinder S., Patel, Amit S., van den Toorn, Leon, van den Blink, Bernt, Boomars, Karin, Hoitsma, Elske, Wijsenbeek, Marlies S., van Manen, Mirjam J. G., van Manen, Mirjam J. G., Wapenaar, Monique, Strookappe, Bert, Drent, Marjolein, Elfferich, Marjon, de Vries, Jolanda, Gosker, Harry R., Birring, Surinder S., Patel, Amit S., van den Toorn, Leon, van den Blink, Bernt, Boomars, Karin, Hoitsma, Elske, and Wijsenbeek, Marlies S.

Published
2016

26. Sarcoidosis and Pain Caused by Small-Fiber Neuropathy

Author

Heij, Lara, Dahan, Albert, and Hoitsma, Elske

Subjects
Article Subject
Abstract

Sarcoidosis is a chronic inflammatory illness and small-fiber neuropathy (SFN) is one of the disabling and often chronic manifestations of the disease. SFN presents with peripheral pain and symptoms of autonomic dysfunction. The character of the pain can be burning or shooting. Besides, allodynia and hyperesthesia can exist. Diagnosis is usually made on the basis of clinical features, in combination with abnormal specialized tests. The aim of treatment is often to reduce pain; however, total pain relieve is seldom achieved. The role of TNF-α in the pathogenesis of SFN in sarcoidosis appears interesting to explore. Novel therapeutic agents such as ARA 290, a nonhematopoietic erythropoietin analogue with potent anti-inflammatory and tissue protective properties, are interesting to explore in the treatment of SFN in sarcoidosis.

Published
2012
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38. Response to letter 'Lymphocyte counts and the risk of COVID-19 in people with MS'.

Author

Loonstra, Floor C, van Kempen, Zoé LE, Strijbis, Eva M, Killestein, Joep, Hoitsma, Elske, and Mostert, Jop P

Subjects
NEUROMYELITIS optica, LYMPHOCYTE count, COVID-19, COVID-19 pandemic, AT-risk people
Abstract

It has been suggested to avoid drug-induced lymphopenia as this might be a risk factor for contracting COVID-19 or for a more severe COVID-19 course in MS patients.[2] In a French COVID-19 MS cohort, lymphocyte counts prior to COVID-19 were not associated with the severity of COVID-19 course.[3] However, when excluding fingolimod-induced lymphopenia, the authors did find an association with more severe course of COVID-19 and lymphopenia. With interest we read the comments of Evangelou and Garjani regarding our report of coronavirus disease 2019 (COVID-19) in the Dutch MS population.[1] In our cohort, we could not find an association regarding lymphopenia and severity of COVID-19 course. We collected lymphocyte counts that were sampled half a year prior to the first COVID-19 case in the Netherlands in patients without known COVID-19 infection later on during the pandemic. [Extracted from the article]

Published
2021
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39. Acknowledgement to Referees.

Subjects
ACOSTA, Maria, ACTA Neuropathologica (Periodical)
Abstract

People that the editorial board of the journal would like to thank for their assistance in the creation of its January 1, 2008 issue are mentioned.

Published
2008
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