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2 results on '"Hepatitis Delta Virus drug effects"'

1. Endpoints and New Options for Treatment of Chronic Hepatitis D

Author

Lok, Anna S, Negro, Francesco, Asselah, Tarik, Farci, Patrizia, and Rizzetto, Mario

Subjects
ddc:616, Treatment Outcome, Hepatitis D, Chronic / diagnosis, Hepatitis D, Chronic / therapy, Antiviral Agents / therapeutic use, Humans, ddc:616.07, Hepatitis Delta Virus / drug effects, Biomarkers
Published
2021

2. Impact of Tenofovir on Hepatitis Delta Virus Replication in the Swiss Human Immunodeficiency Virus Cohort Study

Author

Huldrych F. Günthard, Alexandra Calmy, Patrick Schmid, Andri Rauch, Franziska Suter-Riniker, Nicole Friolet, Gilles Wandeler, Roland Sahli, Andrew Atkinson, Enos Bernasconi, Alexander Lüthi, Matthias Cavassini, Darius Moradpour, Manuel Battegay, Charles Béguelin, University of Zurich, and Béguelin, Charles

Subjects
Male, viruses, Human immunodeficiency virus (HIV), HIV Infections, Virus Replication, medicine.disease_cause, 2726 Microbiology (medical), 10234 Clinic for Infectious Diseases, Cohort Studies, 0302 clinical medicine, Medicine, 030212 general & internal medicine, ddc:616, Chronic/complications/virology, virus diseases, Middle Aged, Viral Load, Hepatitis B, Hepatitis D, Infectious Diseases, Coinfection, Female, 030211 gastroenterology & hepatology, Hepatitis Delta Virus, Hepatitis D/virology, Viral load, HIV Infections/complications/drug therapy, Switzerland, Cohort study, Adult, Microbiology (medical), Hepatitis B virus, Anti-HIV Agents, 610 Medicine & health, Virus, 03 medical and health sciences, Hepatitis B, Chronic, Tenofovir/therapeutic use, Humans, Hepatitis B virus/isolation & purification, Tenofovir, Hepatitis Delta Virus/drug effects/isolation & purification/physiology, Virus Replication/drug effects, business.industry, 2725 Infectious Diseases, biochemical phenomena, metabolism, and nutrition, medicine.disease, Virology, Viral replication, Anti-HIV Agents/therapeutic use, business
Abstract

We analyzed changes in hepatitis B virus and hepatitis delta virus (HDV) viral loads (VL) during tenofovir-containing antiretroviral therapy among patients with a replicating HDV infection in the Swiss HIV Cohort Study. Only 28.6% experienced a ≥2.0 log reduction in HDV RNA, and 14.3% had undetectable HDV VL within 5 years.

Published
2017
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