1,509 results on '"Hengstler, Jan G."'
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2. Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food
3. Role of albumin in the metabolism and excretion of ochratoxin A
4. Acetaminophen overdose causes a breach of the blood–bile barrier in mice but not in rats
5. Integrated data from intravital imaging and HPLC–MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats
6. Correction: Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food
7. EDI3 knockdown in ER-HER2+ breast cancer cells reduces tumor burden and improves survival in two mouse models of experimental metastasis
8. Basal MET phosphorylation is an indicator of hepatocyte dysregulation in liver disease
9. Basic concepts of mixture toxicity and relevance for risk evaluation and regulation
10. PFASs–restriction proposal commentary on ECHA’s Annex XV restriction report, proposal for a restriction, March 2023
11. Comparative metabolism of aflatoxin B1 in mouse, rat and human primary hepatocytes using HPLC–MS/MS
12. Guidance for statistical design and analysis of toxicological dose–response experiments, based on a comprehensive literature review
13. The TGF-β1 target WISP1 is highly expressed in liver cirrhosis and cirrhotic HCC microenvironment and involved in pro- and anti-tumorigenic effects
14. Loss of Toll-like receptor 9 protects from hepatocellular carcinoma in murine models of chronic liver disease
15. Transcriptome-based prediction of drugs, inhibiting cardiomyogenesis in human induced pluripotent stem cells
16. Alterations in the hepatocyte epigenetic landscape in steatosis
17. Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+ breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth
18. Proteome analysis of monocytes implicates altered mitochondrial biology in adults reporting adverse childhood experiences
19. G × E interactions as a basis for toxicological uncertainty
20. PBTK modeling of the pyrrolizidine alkaloid retrorsine to predict liver toxicity in mouse and rat
21. The impact of physical fitness, social life, and cognitive functions on work ability in middle-aged and older adults
22. Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis
23. Induction of steatosis in primary human hepatocytes recapitulates key pathophysiological aspects of metabolic dysfunction-associated steatotic liver disease
24. Model predicts fundamental role of biomechanical control of cell cycle progression during liver regeneration after partial hepatectomy
25. Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation
26. Classification of hepatotoxicity of compounds based on cytotoxicity assays is improved by additional interpretable summaries of high-dimensional gene expression data
27. Risk assessment of parabens in a transcriptomics-based in vitro test
28. Ricin: an ancient toxicant, but still an evergreen
29. Sublethal necroptosis signaling promotes inflammation and liver cancer
30. Genome-wide Association Study of Bladder Cancer Reveals New Biological and Translational Insights
31. Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A
32. Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins
33. Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity
34. Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes
35. Chronic stress is associated with specific path integration deficits
36. Evaluation of the genotoxic potential of acrylamide: Arguments for the derivation of a tolerable daily intake (TDI value)
37. Digital twin demonstrates significance of biomechanical growth control in liver regeneration after partial hepatectomy
38. Stellungnahme zu Acetaldehyd als Aromastoff: Aspekte der Risikobewertung
39. OS-088-YI Selective ablation of Caspase 8 in hepatocytes ameliorates development of metabolic dysfunction-associated steatohepatitis following hepatocyte-specific JNK deletion
40. LBP-017 Liver-kidney crosstalk: the influence of hepatic oxalate release on kidney gluconeogenesis
41. Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds—a hypothesis
42. Recent research on Novichok
43. Identification of an FXR-modulated liver-intestine hybrid state in iPSC-derived hepatocyte-like cells
44. In memoriam Thomas Gebel
45. Long-term prognostic significance of HER2-low and HER2-zero in node-negative breast cancer
46. In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay
47. td2pLL: An intuitive time-dose-response model for cytotoxicity data with varying exposure durations
48. Importance of Xenobiotic Metabolism: Mechanistic Considerations Relevant for Regulation
49. Do Carcinogens Have a Threshold Dose? The Pros and Cons
50. Automated Detection of Portal Fields and Central Veins in Whole-Slide Images of Liver Tissue
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