Search

Objectives: To identify the dermatological system drugs that may be prescribed by Chinese dermatological nurses through expert consensus.

To evaluate the effects of calcium supplementation on bone mineral density in children.

Aim: To assess the effectiveness of decision aids in the treatment, prevention and screening of breast cancer patients. Design: A systematic review and meta‐analysis. Methods: The review protocol was registered in the CRD Prospero database(CRD42020173028). A literature search was carried out in five databases: PubMed, Cochrane, EMBASE, Scopus and Web of science data in January 2020. We used The Cochrane risk bias assessment tool to evaluate the literature quality of included trials and the Review Manager 5.2 software to analyse data. Results: We included 22 studies. Compared with the conventional methods, decision aids reduced treatment decision conflicts and had no significant effect on screening decision conflicts (WMD=−2.25, 95% CI = ‐ 2.64,‐1.87, p <.0001; WMD=−1.37, 95% CI = ‐ 3.57,0.83, p =.22). Three were no statistical differences in participants' anxiety, decision regret, knowledge, informed choice and decision‐making satisfaction between the two groups. [ABSTRACT FROM AUTHOR]

Density functional theory calculations combined with the energy and building-block decomposition analyses have been carried out to investigate the structures, stability orders, redox potentials and proton binding of the six Baker–Figgis isomers (α, β, γ, α*, β* and γ*) of [(SbO6)W18O54(OH)2]9− {H2SbW18} and [(NaF6)W18O54(OH)2]7− {H2NaW18} anions at the level of PBEsol-D3/TZP. Both bonding energy and Gibbs free energy analyses exhibit that the two non-classical Wells–Dawson (WD) species behave quite differently from each other. The pyroanimonate {H2SbW18}, with a stability order of γ* ＞ β* ＞ α ＞ α* ＞ β ＞ γ, is a non-classical WD species, while the hexafluoride {H2NaW18} (α ＞ β ＞ γ ＞ γ* ＞ β* ＞ α*) is a transition intermediate between classical and non-classical WD types, possessing both non-classical ([XW18O60(OH)2]n−, X = I, Te and W) and classical [Si2W18O62]8− properties. Energy decomposition analyses (EDA) reveal that spatial arrangement (Ehost), host–guest fragment interaction energy (FIE), and structural distortion energy (DE) are three key factors governing the relative stability of isomers; among these, DE is always dominant, while FIE and Ehost are subordinated but are still important. Building-block decomposition analyses (BDA) disclose that the octahedral {MO6} units of the equatorial belt, particularly the staggered belt, are always more distorted than those of the two polar caps inside each structure. The theoretical redox potentials demonstrate that the oxidizing power increases with a trend of α ＜ β ＜ γ and α* ＜ β* ＜ γ* for both species, and the first redox potential is closely related to the energy level of the LUMO of each anion. Evaluation of the proton inclusion energies suggests that {H2NaW18} can only embed two protons, while {H2SbW18} may encapsulate four; the number of embedded protons is controlled by both the charge of the heteroatom X and the volume of the tetrahedral {O4}/{OF3} cavity. [ABSTRACT FROM AUTHOR]

As the most important document, the validity of the security target is mostly dependent on the accuracy of security problem definition. However there Is no necessary model and method in the security problem definition process. To reduce the subjectivity, taking IC card international terminal production applied in the online payment as the research object, a method of the threat definition was proposed based on the threat modeling method of the security development lifecycle (SDL) and threat tree analyzing. Furthermore, the definition method and considerations of other contents in security problem definition were illustrated. This paper will lay a foundation for the proposal of accurate security counter-measures in security target. [ABSTRACT FROM AUTHOR]

Dermatomyositis ( DM) is a polygenic disorder characterized by inflammation of skeletal muscle and skin. To date, the exact etiopathogenesis of DM remains elusive. To explore the genetic basis of DM, we conducted genome-wide genotyping analysis of 127 patients and 1566 healthy controls by Illumina Human OmniZhongHua-8 BeadChips in the Chinese Han population. We investigated whether the three SNP (, and ) at 6p21.32 in the HLA- DPB1 gene were significantly associated with DM ( P < 5 × 10−8) and identified two susceptibility loci at 7q34 ( PIP, , P = 7.45 × 10−7, odds ratio [ OR] = 2.71) and 10q24.2 ( CPN1, , P = 9.04 × 10−7, OR = 4.39) with suggestive evidence. We imputed 6674 classical human leukocyte antigen ( HLA) alleles, amino acids and SNP from the discovery dataset, and stepwise analysis revealed that HLA- DPB1*17 in class II HLA genes were significantly associated with DM susceptibility. This study represents the first genome-wide association study ( GWAS) of DM in the Chinese Han population. For the first time, HLA- DPB1 was found to be associated with DM in this population. Moreover, we identified two novel suggestive susceptibility loci ( PIP and CPN1) and confirmed four previously reported genes ( DMB, DQA1, DQB1 and DRB1) having potential associations with DM in the Chinese Han population. Our GWAS results in this population should provide important information regarding the genetic etiopathogenesis of DM and facilitate the development of new therapies for the treatment of DM and the prevention of DM progression. [ABSTRACT FROM AUTHOR]

Based on the features of the forest products trading information, a compound keywords vector space model was utilized to represent the user interest model of the forest products trading information website. Every compound keyword in the vector space consists of three keywords, which are supply and demand classification, the name of the forest product and the production place, and some information about the specifications, price and the company name of the forest products. Every compound keyword has a user interest value. The learning and updating of the user interest model were reaiized through the browsing, registering and releasing behaviors of the users and introducing the forgetting factors for the interest values, respectively. The perssstent interests and the temporary interests of the users were distinguished by introducing a temporary interests group. Finally, the recommendation algorithms based on the contents itering were proposed based on our user interest model, and its advantage was demonstrated by comparison experiments [ABSTRACT FROM AUTHOR]

Akabane virus (AKAV) has been detected in a variety of host species in China, but there are only limited records of its occurrence in goats. However, more attention needs to be paid to understanding the diversity of viruses in this species. The aim of the study was to explore the genotype characteristics and variation trend of AKAV and their relationship with virulence in Yunnan, China. Blood samples were collected from goats during routine surveillance of goat diseases in Yunnan province in 2019. The AKAV CX-01 strain was isolated using BHK-21 cells. To understand pathogenicity, the virus was intraperitoneally (IP) and intracerebrally (IC) inoculated into suckling mice and tissue samples were subsequently analysed histopathologically and immunohistochemically. Akabane virus CX-01 strain induced encephalitis and impairment of the central nervous system with fatal consequences. Phylogenetic analysis based on the ORF sequences of the small segments indicated that the AKAV isolate used was most closely related to the GD18134/2018 Chinese midge and bovine NM BS/1strains, while phylogenetic analysis based on the medium segments showed a close relationship between CX-01 and the Chinese GLXCH01 strain. The CX-01 isolate was related to AKAV genogroup Ia and probably originated from a recombination of different strains. [ABSTRACT FROM AUTHOR]

Copyright of China Harbour Engineering is the property of Editorial Office of China Harbour Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)