8 results on '"Friman, Bo"'
Search Results
2. From Neolithic Boom-and-Bust to Iron Age Peak and Decline: Population and Settlement Dynamics in Southern Sweden Inferred from Summed Radiocarbon Dates.
- Author
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Friman, Bo and Lagerås, Per
- Subjects
- *
RADIOCARBON dating , *UPLANDS , *POPULATION , *IRON Age - Abstract
This article presents 6637 radiocarbon dates from archaeological sites in southernmost Sweden, from 9000 cal bc to the present. Based on summed probability distributions (SPDs) of the calibrated radiocarbon dates, the authors consider long-term trends in settlement and human population. Most dates are from the fertile and densely populated plains of south-western Scania, but coastal lowlands and forested uplands are also represented, allowing for a discussion of the relationship between central and peripheral areas. The authors distinguish between different types of archaeological contexts and features and between different types of dated material, so as to better understand the processes behind population and settlement change. They highlight three periods and phenomena revealed by the SPDs: a strong population increase at the onset of the Neolithic (4000–3700 cal bc), followed by a sharp decline; a steady and long-lasting expansion from the Early Bronze Age to the Roman Iron Age (1500 cal bc–cal ad 200); and a decrease in the Nordic Late Iron Age (seventh century ad), particularly in recently colonized upland areas. The SPDs presented provide a new framework for archaeology in southern Sweden and offer an empirical basis for discussion of long-term trends in settlement and population development. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
3. Att stå på egna ben
- Author
-
Friman, Bo
- Subjects
Malmö ,pit-system ,village ,central functions ,collective ,long-house ,ancestor cult ,possession ,social bonds ,Archaeology ,egalitarian ,Early Iron Age ,elite ,individual ,farm ,manifestation ,Mellanbyn - Abstract
The dissertation can be divided into two parts, the first of which is a detailed analysis of three excavations concerning Mellanbyn in southern Malmö. In the second part I study the more general development of society, relating Mellanbyn to the surrounding area as well as to the region as a whole during Late Bronze Age and the Early Iron Age. The aim can be summed up as being to study the development of society from an individual–collective and egalitarian–elite perspective in the Late Bronze Age and the Early Iron Age. My work is geared to trying to understand changes in the world of ideas, patterns of action and social organization on the basis of changes in settlement, the use of the landscape and deposition patterns of objects. Southern Malmö is inhabited by a seemingly egalitarian settlement with small farming units based on cultivation of hulled barley during phase 1 (800 BC – 400 BC). Egalitarian and collective structures are visible and settlement spread to colonize all the plateaus and heights in the area during phase 2 (350 BC – 100 BC). Farms with collective animal husbandry has acquired a more important role and begun to gain an economic advantage. During phase 3-4 (200 BC – the birth of Christ) the settlement began to be concentrated in village-like structures. The interpretation is that an agricultural reform took place at roughly the same time in two different areas with a view to freeing larger areas of land for tillage and grazing. The process must have been staged by an emerging elite. During phases 5–6 (The birth of Christ – 250 AD) settlement reached its peak in the number of long-houses and farms. The agrarian elite manifested their position and their belonging to the place by construction of large farms and long-houses, sacrificing their agricultural surplus and prestige objects. The major votive ceremonies took place at Mellanbyn. More workshop sites became significant during this period in southern Scandinavia, and this was where new power centres grew up and were consolidated in the Late Roman Iron Age. New elite was founded on the control and trade chiefly of Roman goods but also on the control of the indigenous manufacture of metal objects. Mellanbyn’s lack of important contact networks and control over the production of valuable and prestigious objects also led to its fall in the Late Roman Iron Age. It brought down with it the farms that were directly dependent on it. On the other hand, some areas still had continuous settlement after Mellanbyn ceased to exist as a place with central functions.
- Published
- 2008
4. The effect of tadalafil on psychosocial outcomes in Swedish men with erectile distress: a multicentre, non-randomised, open-label clinical study.
- Author
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Fugl-Meyer, K. S., Stothard, D., Belger, M., Toll, A., Berglund, O., Eliasson, T., and Fugl-Meyer, A. R.
- Subjects
PHOSPHODIESTERASES ,SEXUAL dysfunction ,ENZYME inhibitors ,IMPOTENCE ,THERAPEUTICS ,BIOTECHNOLOGY - Abstract
A multicentre, non-randomised, open-label study assessed whether personal distress caused by erectile dysfunction (ED) affected psychosocial outcomes of tadalafil treatment. Eligible Swedish men at least 18 years old reporting ≥3-month history of ED were stratified into two groups (manifest or mild/no distress) based upon a distress question administered at enrolment. Tadalafil 20 mg was taken as needed for 8 weeks. The primary outcome was the difference between the two distress groups in change from baseline in the Psychological and Interpersonal Relationship Scales (PAIRS) spontaneity domain. Secondary outcome measures were PAIRS sexual self-confidence and time concerns domains, Life Satisfaction (LiSat-11) checklist and a Global Assessment of Treatment Response. The study also assessed tolerability. Of 662 men enrolled, 88% had manifest distress and 12% had mild/no distress. Baseline-to-endpoint changes for PAIRS domains were not significantly different between groups. Baseline-to-endpoint changes in LiSat-11 items were not significantly different between groups except for satisfaction with sexual life. Compared with men without ED, below normal baseline satisfaction with partner relationship and family life were normalised at endpoint. Over 90% of men reported improved erection and ability to engage in sexual activity. The most common treatment-emergent adverse events were headache, myalgia, dyspepsia, flushing and back pain. One man discontinued because of myalgia; 630 (95%) completed the study. In conclusion, erectile distress levels vary among patients with ED and distress can affect intra-familiar aspects of life, which may have implications for clinical practise. However, distress does not appear to hinder improvement in both mechanical and psychosocial outcomes of tadalafil treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2006
- Full Text
- View/download PDF
5. Att stå på egna ben.
- Abstract
The dissertation can be divided into two parts, the first of which is a detailed analysis of three excavations concerning Mellanbyn in southern Malmö. In the second part I study the more general development of society, relating Mellanbyn to the surrounding area as well as to the region as a whole during Late Bronze Age and the Early Iron Age. The aim can be summed up as being to study the development of society from an individual–collective and egalitarian–elite perspective in the Late Bronze Age and the Early Iron Age. My work is geared to trying to understand changes in the world of ideas, patterns of action and social organization on the basis of changes in settlement, the use of the landscape and deposition patterns of objects. Southern Malmö is inhabited by a seemingly egalitarian settlement with small farming units based on cultivation of hulled barley during phase 1 (800 BC – 400 BC). Egalitarian and collective structures are visible and settlement spread to colonize all the plateaus and heights in the area during phase 2 (350 BC – 100 BC). Farms with collective animal husbandry has acquired a more important role and begun to gain an economic advantage. During phase 3-4 (200 BC – the birth of Christ) the settlement began to be concentrated in village-like structures. The interpretation is that an agricultural reform took place at roughly the same time in two different areas with a view to freeing larger areas of land for tillage and grazing. The process must have been staged by an emerging elite. During phases 5–6 (The birth of Christ – 250 AD) settlement reached its peak in the number of long-houses and farms. The agrarian elite manifested their position and their belonging to the place by construction of large farms and long-houses, sacrificing their agricultural surplus and prestige objects. The major votive ceremonies took place at Mellanbyn. More workshop sites became significant during this period in southern Scandinavia, and this was where new power ce
- Published
- 2008
6. Inhibition of integrin αVβ6 changes fibril thickness of stromal collagen in experimental carcinomas.
- Author
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Olof Olsson, P., Gustafsson, Renata, Salnikov, Alexei V., Göthe, Maria, Zeller, Kathrin S., Friman, Tomas, Baldetorp, Bo, Koopman, Louise A., Weinreb, Paul H., Violette, Shelia M., Kalamajski, Sebastian, Heldin, Nils-Erik, and Rubin, Kristofer
- Subjects
ADENOCARCINOMA ,CANCER treatment ,CANCER chemotherapy ,DRUG therapy ,IMATINIB ,DRUG efficacy ,TRANSFORMING growth factors-beta ,EXTRACELLULAR matrix ,INTEGRINS - Abstract
Background: Chemotherapeutic efficacy can be improved by targeting the structure and function of the extracellular matrix (ECM) in the carcinomal stroma. This can be accomplished by e.g. inhibiting TGF-β1 and -β3 or treating with Imatinib, which results in scarcer collagen fibril structure in xenografted human KAT-4/HT29 (KAT-4) colon adenocarcinoma. Methods: The potential role of α
V β6 integrin-mediated activation of latent TGF-β was studied in cultured KAT-4 and Capan-2 human ductal pancreatic carcinoma cells as well as in xenograft carcinoma generated by these cells. The monoclonal αV β6 integrin-specific monoclonal antibody 3G9 was used to inhibit the αV β6 integrin activity. Results: Both KAT-4 and Capan-2 cells expressed the αV β6 integrin but only KAT-4 cells could utilize this integrin to activate latent TGF-β in vitro. Only when Capan-2 cells were co-cultured with human F99 fibroblasts was the integrin activation mechanism triggered, suggesting a more complex, fibroblast-dependent, activation pathway. In nude mice, a 10-day treatment with 3G9 reduced collagen fibril thickness and interstitial fluid pressure in KAT-4 but not in the more desmoplastic Capan-2 tumors that, to achieve a similar effect, required a prolonged 3G9 treatment. In contrast, a 10-day direct inhibition of TGF-β1 and -β3 reduced collagen fibril thickness in both tumor models. Conclusion: Our data demonstrate that the αV β6 -directed activation of latent TGF-β plays a pivotal role in modulating the stromal collagen network in carcinoma, but that the sensitivity to αV β6 inhibition depends on the simultaneous presence of alternative paths for latent TGF-β activation and the extent of desmoplasia. [ABSTRACT FROM AUTHOR]- Published
- 2018
- Full Text
- View/download PDF
7. The Liminal Horse : Equitation and Boundaries
- Author
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Rena Maguire, Anastasija Ropa, Rena Maguire, and Anastasija Ropa
- Subjects
- Liminality, Horses--History
- Abstract
The historical horse is at once material and abstract, as is the notion of the border. Borders and frontiers are not only markers delineating geographical spaces but also mental constructs: there are borders between order and disorder, between what is permitted and what is prohibited. Boundaries and liminal spaces also exist in the material, economic, political, moral, legal and religious spheres. In this volume, the contributing authors explore the theme of the liminality of the horse in all of these historical arenas, asking how does one reconcile the very different roles played by the horse in human history?
- Published
- 2021
8. The Agrarian History of Sweden : From 4000 BC to AD 2000
- Author
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Janken Myrdal, Mats Morell, Janken Myrdal, and Mats Morell
- Subjects
- Agriculture--Sweden--History
- Abstract
Comprehensive and concise, this account details the agrarian history of Sweden - as it is defined by its present national borders - from the Neolithic times to present day. Key historical concepts and events are discussed, including the introduction of planned agriculture alongside the domestication of animals; the feudal relationships and interactions between men and women, various age groups, and different social classes during the Middle Ages; the changes brought about by industrialism and the development of political democracy; the effects of World Wars I and II; and Sweden's inclusion in the European Union in 1995. This study also examines the interdependence between agriculture and other industries as well as the relationship between agriculture and politics on a local, regional, national, and international level.
- Published
- 2011
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