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21 results on '"Feasey, Helena R. A."'

3. Tuberculosis Immunoreactivity Surveillance in Malawi (Timasamala)—A protocol for a cross-sectional Mycobacterium tuberculosis immunoreactivity survey in Blantyre, Malawi

Author

Rickman, Hannah M., primary, Phiri, Mphatso D., additional, Feasey, Helena R. A., additional, Mbale, Hannah, additional, Nliwasa, Marriott, additional, Semphere, Robina, additional, Chagaluka, George, additional, Fielding, Katherine, additional, Mwandumba, Henry C., additional, Horton, Katherine C., additional, Nightingale, Emily S., additional, Henrion, Marc Y. R., additional, Mbendera, Kuzani, additional, Mpunga, James A., additional, Corbett, Elizabeth L., additional, and MacPherson, Peter, additional

Published
2024
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7. Impact of active case-finding for tuberculosis on case-notifications in Blantyre, Malawi: A community-based cluster-randomised trial (SCALE)

Author

Feasey, Helena R. A., primary, Khundi, McEwen, additional, Soko, Rebecca Nzawa, additional, Bottomley, Christian, additional, Chiume, Lingstone, additional, Burchett, Helen E. D., additional, Nliwasa, Marriott, additional, Twabi, Hussein H., additional, Mpunga, James A., additional, MacPherson, Peter, additional, and Corbett, Elizabeth L., additional

Published
2023
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8. Prevalence of bacteriologically-confirmed pulmonary tuberculosis in urban Blantyre, Malawi 2019–20: Substantial decline compared to 2013–14 national survey

Author

Feasey, Helena R. A., primary, Khundi, McEwen, additional, Nzawa Soko, Rebecca, additional, Nightingale, Emily, additional, Burke, Rachael M., additional, Henrion, Marc Y. R., additional, Phiri, Mphatso D., additional, Burchett, Helen E., additional, Chiume, Lingstone, additional, Nliwasa, Marriott, additional, Twabi, Hussein H., additional, Mpunga, James A., additional, MacPherson, Peter, additional, and Corbett, Elizabeth L., additional

Published
2023
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10. Impact of community-wide tuberculosis active case finding and HIV testing on tuberculosis trends in Malawi

Author

Burke, Rachael M, primary, Nliwasa, Marriott, additional, Dodd, Peter J, additional, Feasey, Helena R, additional, Khundi, McEwen, additional, Choko, Augustine, additional, Nzawa-Soko, Rebecca, additional, Mpunga, James, additional, Webb, Emily L, additional, Fielding, Katherine, additional, MacPherson, Peter, additional, and Corbett, Elizabeth L, additional

Published
2023
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11. Impact of Community-Wide Tuberculosis Active Case Finding and Human Immunodeficiency Virus Testing on Tuberculosis Trends in Malawi.

Author

Burke, Rachael M, Nliwasa, Marriott, Dodd, Peter J, Feasey, Helena R A, Khundi, McEwen, Choko, Augustine, Nzawa-Soko, Rebecca, Mpunga, James, Webb, Emily L, Fielding, Katherine, MacPherson, Peter, and Corbett, Elizabeth L

Subjects
HIV infection epidemiology, TUBERCULOSIS epidemiology, DIAGNOSIS of HIV infections, TUBERCULOSIS diagnosis, PUBLIC health surveillance, CONFIDENCE intervals, COMMUNITY health services, MEDICAL screening, POPULATION geography, AIDS serodiagnosis, COMPARATIVE studies, TIME series analysis, DESCRIPTIVE statistics, DISEASE prevalence, RESEARCH funding, ADULTS
Abstract

Background Tuberculosis case-finding interventions are critical to meeting World Health Organization End TB strategy goals. We investigated the impact of community-wide tuberculosis active case finding (ACF) alongside scale-up of human immunodeficiency virus (HIV) testing and care on trends in adult tuberculosis case notification rates (CNRs) in Blantyre, Malawi. Methods Five rounds of ACF for tuberculosis (1–2 weeks of leafleting, door-to-door enquiry for cough and sputum microscopy) were delivered to neighborhoods ("ACF areas") in North-West Blantyre between April 2011 and August 2014. Many of these neighborhoods also had concurrent HIV testing interventions. The remaining neighborhoods in Blantyre City ("non-ACF areas") provided a non-randomized comparator. We analyzed TB CNRs from January 2009 until December 2018. We used interrupted time series analysis to compare tuberculosis CNRs before ACF and after ACF, and between ACF and non-ACF areas. Results Tuberculosis CNRs increased in Blantyre concurrently with start of ACF for tuberculosis in both ACF and non-ACF areas, with a larger magnitude in ACF areas. Compared to a counterfactual where pre-ACF CNR trends continued during ACF period, we estimated there were an additional 101 (95% confidence interval [CI] 42 to 160) microbiologically confirmed (Bac+) tuberculosis diagnoses per 100 000 person-years in the ACF areas in 3 and a half years of ACF. Compared to a counterfactual where trends in ACF area were the same as trends in non-ACF areas, we estimated an additional 63 (95% CI 38 to 90) Bac + diagnoses per 100 000 person-years in the same period. Conclusions Tuberculosis ACF was associated with a rapid increase in people diagnosed with tuberculosis in Blantyre. [ABSTRACT FROM AUTHOR]

Published
2023
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12. Neighbourhood prevalence-to-notification ratios for adult bacteriologically-confirmed tuberculosis reveals hotspots of underdiagnosis in Blantyre, Malawi

Author

Khundi, McEwen, primary, Carpenter, James R., additional, Corbett, Elizabeth L., additional, Feasey, Helena R. A., additional, Soko, Rebecca Nzawa, additional, Nliwasa, Marriott, additional, Twabi, Hussein, additional, Chiume, Lingstone, additional, Burke, Rachael M., additional, Horton, Katherine C., additional, Dodd, Peter J., additional, Cohen, Ted, additional, and MacPherson, Peter, additional

Published
2022
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13. Do community-based active case-finding interventions have indirect impacts on wider TB case detection and determinants of subsequent TB testing behaviour? A systematic review

Author

Feasey, Helena R. A., primary, Burke, Rachael M., additional, Nliwasa, Marriott, additional, Chaisson, Lelia H., additional, Golub, Jonathan E., additional, Naufal, Fahd, additional, Shapiro, Adrienne E., additional, Ruperez, Maria, additional, Telisinghe, Lily, additional, Ayles, Helen, additional, Miller, Cecily, additional, Burchett, Helen E. D., additional, MacPherson, Peter, additional, and Corbett, Elizabeth L., additional

Published
2021
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14. Pattern of abnormalities amongst chest X‐rays of adults undergoing computer‐assisted digital chest X‐ray screening for tuberculosis in Peri‐Urban Blantyre, Malawi: A cross‐sectional study

Author

Twabi, Hussein H., primary, Semphere, Robina, additional, Mukoka, Madalo, additional, Chiume, Lingstone, additional, Nzawa, Rebecca, additional, Feasey, Helena R. A., additional, Lipenga, Trancizeo, additional, MacPherson, Peter, additional, Corbett, Elizabeth L., additional, and Nliwasa, Marriott, additional

Published
2021
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15. Additional file 1 of Durations of asymptomatic, symptomatic, and care-seeking phases of tuberculosis disease with a Bayesian analysis of prevalence survey and notification data

Author

Ku, Chu-Chang, MacPherson, Peter, Khundi, McEwen, Nzawa Soko, Rebecca H., Feasey, Helena R. A., Nliwasa, Marriott, Horton, Katherine C., Corbett, Elizabeth L., and Dodd, Peter J.

Abstract

Additional file 1. Supplementary materials including: Sources of data; Model details; Inference on delay and duration, posterior distribution by country sensitivity analysis

Published
2021
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17. Tuberculosis Diagnosis Cascade in Blantyre, Malawi: A Prospective Cohort Study

Author

Feasey, Helena R A, primary, Corbett, Elizabeth L, additional, Nliwasa, Marriott, additional, Mair, Luke, additional, Divala, Titus H, additional, Kamchedzera, Wala, additional, Khundi, McEwen, additional, Burchett, Helen E D, additional, Webb, Emily L, additional, Maheswaran, Hendramoorthy, additional, Squire, S Bertel, additional, and MacPherson, Peter, additional

Published
2020
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18. Provider-initiated HIV testing and TB screening in the era of universal coverage: Are the right people being reached? A cohort study in Blantyre, Malawi

Author

Mair, Luke, primary, Corbett, Elizabeth L., additional, Feasey, Helena R. A., additional, Kamchedzera, Wala, additional, Khundi, McEwen, additional, Lalloo, David G., additional, Maheswaran, Hendramoorthy, additional, Nliwasa, Marriott, additional, Squire, S. Bertel, additional, Webb, Emily L., additional, and MacPherson, Peter, additional

Published
2020
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19. Effects of Coronavirus Disease Pandemic on Tuberculosis Notifications, Malawi.

Author

Soko, Rebecca Nzawa, Burke, Rachael M., Feasey, Helena R. A., Sibande, Wakumanya, Nliwasa, Marriott, Henrion, Marc Y. R., Khundi, McEwen, Dodd, Peter J., Chu Chang Ku, Kawalazira, Gift, Choko, Augustine T., Divala, Titus H., Corbett, Elizabeth L., MacPherson, Peter, and Ku, Chu Chang

Subjects
COVID-19, COVID-19 pandemic, TUBERCULOSIS, TIME series analysis, PERSONAL protective equipment
Abstract

The coronavirus disease (COVID-19) pandemic might affect tuberculosis (TB) diagnosis and patient care. We analyzed a citywide electronic TB register in Blantyre, Malawi and interviewed TB officers. Malawi did not have an official COVID-19 lockdown but closed schools and borders on March 23, 2020. In an interrupted time series analysis, we noted an immediate 35.9% reduction in TB notifications in April 2020; notifications recovered to near prepandemic numbers by December 2020. However, 333 fewer cumulative TB notifications were received than anticipated. Women and girls were affected more (30.7% fewer cases) than men and boys (20.9% fewer cases). Fear of COVID-19 infection, temporary facility closures, inadequate personal protective equipment, and COVID-19 stigma because of similar symptoms to TB were mentioned as reasons for fewer people being diagnosed with TB. Public health measures could benefit control of both TB and COVID-19, but only if TB diagnostic services remain accessible and are considered safe to attend. [ABSTRACT FROM AUTHOR]

Published
2021
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