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8. Pediatric Aerodigestive Medicine: Advancing Collaborative Care for Children With Oropharyngeal Dysphagia

Author

Krasaelap, Amornluck, primary, Duncan, Daniel R., additional, Sabe, Ramy M. M., additional, Bhardwaj, Vrinda, additional, Lerner, Diana G., additional, Gold, Benjamin D., additional, Boesch, Richard Paul, additional, Faure, Christophe, additional, von Allmen, Daniel, additional, Williams, Dana, additional, Chiou, Eric, additional, DeBoer, Emily, additional, Hysinger, Erik, additional, Maybee, Jennifer, additional, Khlevner, Julie, additional, Larson, Kara, additional, Morris, Kimberly, additional, Jalali, Lauren, additional, McSweeney, Maireade, additional, Brigger, Matthew T., additional, Greifer, Melanie, additional, Rutter, Michael, additional, Williams, Nina, additional, Subramanyan, Ram Kumar, additional, Ryan, Matthew J., additional, Acra, Sari, additional, Pentiuk, Scott, additional, Friedlander, Joel, additional, Sobol, Steven E., additional, Kaul, Ajay, additional, Dorfman, Lev, additional, Darbari, Anil, additional, Prager, Jeremy D., additional, Rosen, Rachel, additional, Cocjin, Jose T., additional, and Mousa, Hayat, additional

Published
2023
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23. The Impact of the AAP BRUE Guidelines on Gastrointestinal Testing and Prescribing Practices

Author

Duncan, Daniel R., Growdon, Amanda S., Liu, Enju, Larson, Kara, Gonzalez, Madeline, Norris, Kerri, and Rosen, Rachel L.

Subjects
Male, Infant, Hospitals, Pediatric, Patient Readmission, Pediatrics, Article, Patient Discharge, United States, Hospitalization, Medically Unexplained Symptoms, Prescriptions, Risk Factors, Practice Guidelines as Topic, Gastroesophageal Reflux, Humans, Female, Practice Patterns, Physicians', Algorithms, Societies, Medical, Boston, Retrospective Studies
Abstract

OBJECTIVES: To determine if hospitalization, testing, diagnosis and management of suspected gastroesophageal reflux, and follow-up visits decreased since introduction of American Academy of Pediatrics guidelines for brief resolved unexplained events (BRUE) s. STUDY DESIGN: We performed a retrospective cohort study of infants with BRUE evaluated at Boston Children’s Hospital in the year before and after guideline implementation to determine if practice patterns have changed. Outcomes included hospitalization rates, frequency of swallow assessments, other diagnostic testing, and reflux diagnoses, cost of care and number of repeat visits. Groups were compared based on whether they presented before or after guideline implementation. RESULTS: 359 subjects (186 pre-, 173 post-guidelines) were identified. There were no significant differences in practice patterns or outcomes before or after guideline implementation. Subjects had mean age 2.53±0.15 months and 80% were hospitalized for 2.49±0.26 days. Each subject had 2.47 diagnostic tests performed and 89% were noncontributory. Despite only13% having videofluoroscopic swallow study performed, 72% showed aspiration/penetration. No subject had gastroesophageal reflux testing, yet reflux was implicated as the cause for admission in 40% of subjects, resulting in increased odds of discharge on acid suppressing medications (OR 2.88, 95% CI 1.68-4.92, P = .0001). In follow-up, 28% of subjects had repeat hospitalizations or emergency room visits for persistent symptoms. CONCLUSIONS: Infants with BRUE continue to undergo low-yield diagnostic testing and after admission remain symptomatic and frequently re-present to medical care. Swallow testing remains infrequent despite its high-yield, reflux continues to be implicated and children are still being discharged on acid suppression despite lack of efficacy.

Published
2019

33. Evaluating the adherence to national guidelines for treatment of gastroesophageal reflux in infants.

Author

Tracy, Michaela S., Duncan, Daniel R., and Rosen, Rachel L.

Subjects
*GASTROESOPHAGEAL reflux, *INFANTS, *PEDIATRIC clinics
Abstract

Abbreviations GERD Gastroesophageal reflux disease GI Gastroenterology H2RA H2 antagonist PCP Primary care physician PPI Proton pump inhibitor Many infants with fussiness or spitting-up are prescribed acid suppression therapy with proton pump inhibitors (PPIs) and H2 antagonists (H2RAs) despite data suggesting these therapies do not improve symptoms over placebo.1,2 Furthermore, there are risks with acid suppression treatment, including increasing rates of gastroenteritis, pneumonia and necrotising enterocolitis.3 In 2018, the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) and the European Society of Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) released updated clinical practice guidelines for the management of gastroesophageal reflux disease (GERD) for infants.4 The guidelines recommend thickening and trial of hypoallergenic formula as first-line therapies for the treatment of GERD in infants, as well as referral to gastroenterology (GI) clinician prior to starting acid suppression. Also, the patients in this study had severe enough symptoms to require referral to GI clinic; thus, our data does not capture changes made by primary care providers for patients who had symptom resolution. [Extracted from the article]

Published
2022
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34. A critical role for macrophages in neovessel formation and the development of stenosis in tissue‐engineered vascular grafts

Author

Hibino, Narutoshi, primary, Yi, Tai, additional, Duncan, Daniel R., additional, Rathore, Animesh, additional, Dean, Ethan, additional, Naito, Yuji, additional, Dardik, Alan, additional, Kyriakides, Themis, additional, Madri, Joseph, additional, Pober, Jordan S., additional, Shinoka, Toshiharu, additional, and Breuer, Christopher K., additional

Published
2011
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35. Determining the fate of seeded cells in venous tissue‐engineered vascular grafts using serial MRI

Author

Harrington, Jamie K., primary, Chahboune, Halima, additional, Criscione, Jason M., additional, Li, Alice Y., additional, Hibino, Narutoshi, additional, Yi, Tai, additional, Villalona, Gustavo A., additional, Kobsa, Serge, additional, Meijas, Dane, additional, Duncan, Daniel R., additional, Devine, Lesley, additional, Papademetri, Xenophon, additional, Shin'oka, Toshiharu, additional, Fahmy, Tarek M., additional, and Breuer, Christopher K., additional

Published
2011
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36. Tissue‐engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel

Author

Hibino, Narutoshi, primary, Villalona, Gustavo, additional, Pietris, Nicholas, additional, Duncan, Daniel R., additional, Schoffner, Adam, additional, Roh, Jason D., additional, Yi, Tai, additional, Dobrucki, Lawrence W., additional, Mejias, Dane, additional, Sawh‐Martinez, Rajendra, additional, Harrington, Jamie K., additional, Sinusas, Albert, additional, Krause, Diane S., additional, Kyriakides, Themis, additional, Saltzman, W. Mark, additional, Pober, Jordan S., additional, Shin'oka, Toshiharu, additional, and Breuer, Christopher K., additional

Published
2011
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38. Cell-Seeding Techniques in Vascular Tissue Engineering

Author

Villalona, Gustavo A., primary, Udelsman, Brooks, additional, Duncan, Daniel R., additional, McGillicuddy, Edward, additional, Sawh-Martinez, Rajendra F., additional, Hibino, Narutoshi, additional, Painter, Christopher, additional, Mirensky, Tamar, additional, Erickson, Benjamin, additional, Shinoka, Toshiharu, additional, and Breuer, Christopher K., additional

Published
2010
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42. Baseball Prospectus 2022

Author

Baseball Prospectus and Baseball Prospectus

Subjects
Baseball players--Rating of--United States, Baseball--Statistics, Baseball--Statistical methods
Abstract

The 2022 edition of The New York Times Bestselling Guide.PLAY BALL! The 27th edition of this industry-leading baseball annual contains all of the important statistics, player predictions and insider-level commentary that readers have come to expect, along with significant improvements to several statistics that were created by, and are exclusive to, Baseball Prospectus, and an expanded focus on international players and teams.Baseball Prospectus 2022 provides fantasy players and insiders alike with prescient PECOTA projections, which The New York Times called “the überforecast of every player's performance.”With more than 50 Baseball Prospectus alumni currently working for major-league baseball teams, nearly every organization has sought the advice of current or former BP analysts, and readers of Baseball Prospectus 2022 will understand why!

Published
2022

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