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4. Breast-Feeding and Childhood-Onset Type 1 Diabetes: A pooled analysis of individual participant data from 43 observational studies

Author

Cardwell, Chris R., Stene, Lars C., Ludvigsson, Johnny, Rosenbauer, Joachim, Cinek, Ondrej, Svensson, Jannet, Perez-Bravo, Francisco, Memon, Anjum, Gimeno, Suely G., Wadsworth, Emma J.K., Strotmeyer, Elsa S., Goldacre, Michael J., Radon, Katja, Chuang, Lee-Ming, Parslow, Roger C., Chetwynd, Amanda, Karavanaki, Kyriaki, Brigis, Girts, Pozzilli, Paolo, UrbonaitĖ, Brone, Schober, Edith, Devoti, Gabriele, Sipetic, Sandra, Joner, Geir, Ionescu-Tirgoviste, Constantin, de Beaufort, Carine E., Harrild, Kirsten, Benson, Victoria, Savilahti, Erkki, Ponsonby, Anne-Louise, Salem, Mona, Rabiei, Samira, and Patterson, Chris C.

Published
2012
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5. Interbirth Interval Is Associated With Childhood Type 1 Diabetes Risk

Author

Cardwell, Chris R., Svensson, Jannet, Waldhoer, Thomas, Ludvigsson, Johnny, Sadauskaitė-Kuehne, Vaiva, Roberts, Christine L., Parslow, Roger C., Wadsworth, Emma J.K., Brigis, Girts, Urbonaitė, Brone, Schober, Edith, Devoti, Gabriele, Ionescu-Tirgoviste, Constantin, de Beaufort, Carine E., Soltesz, Gyula, and Patterson, Chris C.

Published
2012
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6. Birth order and childhood type 1 diabetes risk: a pooled analysis of 31 observational studies

Author

Cardwell, Chris R, Stene, Lars C, Joner, Geir, Bulsara, Max K, Cinek, Ondrej, Rosenbauer, Joachim, Ludvigsson, Johnny, Svensson, Jannet, Goldacre, Michael J, Waldhoer, Thomas, Jarosz-Chobot, Przemysława, Gimeno, Suely GA, Chuang, Lee-Ming, Roberts, Christine L, Parslow, Roger C, Wadsworth, Emma JK, Chetwynd, Amanda, Brigis, Girts, Urbonaitė, Brone, Šipetić, Sandra, Schober, Edith, Devoti, Gabriele, Ionescu-Tirgoviste, Constantin, de Beaufort, Carine E, Stoyanov, Denka, Buschard, Karsten, Radon, Katja, Glatthaar, Christopher, and Patterson, Chris C

Published
2011
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7. Maternal Age at Birth and Childhood Type 1 Diabetes: A Pooled Analysis of 30 Observational Studies

Author

Cardwell, Chris R., Stene, Lars C., Joner, Geir, Bulsara, Max K., Cinek, Ondrej, Rosenbauer, Joachim, Ludvigsson, Johnny, Jané, Mireia, Svensson, Jannet, Goldacre, Michael J., Waldhoer, Thomas, Jarosz-Chobot, Przemysława, Gimeno, Suely G.A., Chuang, Lee-Ming, Parslow, Roger C., Wadsworth, Emma J.K., Chetwynd, Amanda, Pozzilli, Paolo, Brigis, Girts, Urbonaitė, Brone, Šipetić, Sandra, Schober, Edith, Devoti, Gabriele, Ionescu-Tirgoviste, Constantin, de Beaufort, Carine E., Stoyanov, Denka, Buschard, Karsten, and Patterson, Chris C.

Published
2010

8. Lifestyles and socio-cultural factors among children aged 6-8 years from five Italian towns: The MAPEC-LIFE study cohort

Author

Bagordo, Francesco, De Donno, Antonella, Grassi, Tiziana, Guido, Marcello, Devoti, Gabriele, Ceretti, Elisabetta, Zani, Claudia, Feretti, Donatella, Villarini, Milena, Moretti, Massimo, Salvatori, Tania, Carducci, Annalaura, Verani, Marco, Casini, Beatrice, Bonetta, Sara, Carraro, Elisabetta, Schilirò, Tiziana, Bonizzoni, Silvia, Bonetti, Alberto, Gelatti, Umberto, Serio, Francesca, De Giorgi, Mattia, Idolo, Adele, Verri, Tiziano, Covolo, Loredana, Donato, Francesco, Festa, Andrea, Limina, Rosa Maria, Zerbini, Ilaria, Fatigoni, Cristina, Levorato, Sara, Monarca, Silvano, Vannini, Samuele, Donzelli, Gabriele, Bruni, Beatrice, Palomba, Giacomo, Bonetta, Silvia, Gea, Marta, Gilli, Giorgio, Pignata, Cristina, Romanazzi, Valeria, Furia, Camilla, Codenotti, Roberta, Colombi, Paolo, Crottini, Stefano, Gaffurini, Laura, Zagni, Licia, Bagordo, Francesco, De Donno, Antonella, Grassi, Tiziana, Guido, Marcello, Devoti, Gabriele, Ceretti, Elisabetta, Zani, Claudia, Feretti, Donatella, Villarini, Milena, Moretti, Massimo, Salvatori, Tania, Carducci, Annalaura, Verani, Marco, Casini, Beatrice, Bonetta, Sara, Carraro, Elisabetta, Schilirò, Tiziana, Bonizzoni, Silvia, Bonetti, Alberto, Gelatti, Umberto, Serio, Francesca, De Giorgi, Mattia, Idolo, Adele, Verri, Tiziano, Covolo, Loredana, Donato, Francesco, Festa, Andrea, Limina, Rosa Maria, Zerbini, Ilaria, Fatigoni, Cristina, Levorato, Sara, Monarca, Silvano, Vannini, Samuele, Donzelli, Gabriele, Bruni, Beatrice, Palomba, Giacomo, Bonetta, Silvia, Gea, Marta, Gilli, Giorgio, Pignata, Cristina, Romanazzi, Valeria, Furia, Camilla, Codenotti, Roberta, Colombi, Paolo, Crottini, Stefano, Gaffurini, Licia, Zagni, Licia, Donzelli, Gabriela, Gaffurini, Laura, and Zagni, Licia.

Subjects
Male, Parents, Passive smoking, Health Status, Health Behavior, 010501 environmental sciences, medicine.disease_cause, 01 natural sciences, Air pollution, Children, Exposure, Lifestyles, MAPEC-LIFE Study, Questionnaire, Public Health, Environmental and Occupational Health, Cohort Studies, 0302 clinical medicine, Surveys and Questionnaires, Epidemiology, Medicine, 030212 general & internal medicine, Child, MAPEC_LIFE Study, Family Characteristics, Children, Lifestyles, Exposure, Air pollution, Questionnaire, MAPEC_LIFE Study, lcsh:Public aspects of medicine, Italy, Cohort, Female, Seasons, Public Health, Research Article, medicine.medical_specialty, 03 medical and health sciences, Environmental health, Humans, Cities, Life Style, 0105 earth and related environmental sciences, business.industry, Public health, Environmental and Occupational Health, lcsh:RA1-1270, Anthropometry, medicine.disease, Lifestyle, Obesity, Socioeconomic Factors, Tobacco Smoke Pollution, Residence, Biostatistics, business
Abstract

Background Lifestyles profoundly determine the quality of an individual’s health and life since his childhood. Many diseases in adulthood are avoidable if health-risk behaviors are identified and improved at an early stage of life. The aim of the present research was to characterize a cohort of children aged 6–8 years selected in order to perform an epidemiological molecular study (the MAPEC_LIFE study), investigate lifestyles of the children that could have effect on their health status, and assess possible association between lifestyles and socio-cultural factors. Methods A questionnaire composed of 148 questions was administered in two different seasons to parents of children attending 18 primary schools in five Italian cities (Torino, Brescia, Pisa, Perugia and Lecce) to obtain information regarding the criteria for exclusion from the study, demographic, anthropometric and health information on the children, as well as some aspects on their lifestyles and parental characteristics. The results were analyzed in order to assess the frequency of specific conditions among the different seasons and cities and the association between lifestyles and socio-economic factors. Results The final cohort was composed of 1,164 children (50.9 boys, 95.4% born in Italy). Frequency of some factors appeared different in terms of the survey season (physical activity in the open air, the ways of cooking certain foods) and among the various cities (parents’ level of education and rate of employment, sport, traffic near the home, type of heating, exposure to passive smoking, ways of cooking certain foods). Exposure to passive smoking and cooking fumes, obesity, residence in areas with heavy traffic, frequency of outdoor play and consumption of barbecued and fried foods were higher among children living in families with low educational and/or occupational level while children doing sports and consuming toasted bread were more frequent in families with high socio-economic level. Conclusions The socio-economic level seems to affect the lifestyles of children enrolled in the study including those that could cause health effects. Many factors are linked to the geographical area and may depend on environmental, cultural and social aspects of the city of residence.

Published
2017

10. The MAPEC_LIFE Study: indoor/outdoor air pollution exposure and lifestyles of the prospective cohort

Author

De Donno Antonella, Bagordo Francesco, Zani C, Ceretti E, Villarini M, Vannini S, Carducci A, Casini B, Bonetta Sara, Schilirò T, Bonizzoni S, Bonetti A, Grassi Tiziana, Guido Marcello, Devoti Gabriele, Gelatti U, DE DONNO, Maria Antonella, Bagordo, Francesco, Zani, C, Ceretti, E, Villarini, M, Vannini, S, Carducci, A, Casini, B, Bonetta, Sara, Schilirò, T, Bonizzoni, S, Bonetti, A, Grassi, Tiziana, Guido, Marcello, Devoti, Gabriele, and Gelatti, U

Published
2016

11. Exposure to air pollution and lifestyles of children partecipating in the MAPEC_LIFE (Monitoring Air Pollution Effects on Children for Supporting public health policy) study

Author

GRASSI, Tiziana, DE DONNO, Maria Antonella, BAGORDO, Francesco, GUIDO, Marcello, DEVOTI, Gabriele, Ceretti, E, Viola, Gcv, Moretti, M, Levorato, S, Carducci, A, Verani, M, Bonetta, Sa, Bonetta, Si, Bonetti, A, Gelatti, U., Grassi, Tiziana, DE DONNO, Maria Antonella, Bagordo, Francesco, Ceretti, E, Viola, Gcv, Moretti, M, Levorato, S, Carducci, A, Verani, M, Bonetta, Sa, Bonetta, Si, Bonetti, A, Guido, Marcello, Devoti, Gabriele, and Gelatti, U.

Published
2016

12. Feasibility and reliability of a questionnaire for evaluation of the exposure to indoor and outdoor air pollutants, diet and physical activity in 6-8-year-old children

Author

Zani, C, Donato, F, Grioni, S, Viola, G. C. V, Ceretti, E, Feretti, D, Festa, A, Bonizzoni, S, Bonetti, A, Monarca, S, Villarini, M, Levorato, S, Carducci, A, Verani, M, Casini, B, Carraro, E, Gilli, G, Bonetta, S, Gelatti, U, Covolo, L, Levaggi, R, Limina, RM, Mazzoleni, G, Zerbini, I, Furia, C, Marrese, MR, Colombi, P, Mario, E, Braga, F, Fatigoni, C, Moretti, M, Vannini, S, Bruni, B, Caponi, E, Donzelli, G, Tumolo, MR, Romanazzi, V, Pignata, C, Schilirò T., DE DONNO, Maria Antonella, GRASSI, Tiziana, IDOLO, ADELE, BAGORDO, Francesco, GUIDO, Marcello, DEVOTI, Gabriele, SERIO, FRANCESCA, Zani, C, Donato, F, Grioni, S, Viola, G. C. V, Ceretti, E, Feretti, D, Festa, A, Bonizzoni, S, Bonetti, A, Monarca, S, Villarini, M, Levorato, S, Carducci, A, Verani, M, Casini, B, DE DONNO, Maria Antonella, Grassi, Tiziana, Idolo, Adele, Carraro, E, Gilli, G, Bonetta, S, Gelatti, U, Covolo, L, Levaggi, R, Limina, Rm, Mazzoleni, G, Zerbini, I, Furia, C, Marrese, Mr, Colombi, P, Mario, E, Braga, F, Fatigoni, C, Moretti, M, Vannini, S, Bruni, B, Caponi, E, Donzelli, G, Bagordo, Francesco, Guido, Marcello, Devoti, Gabriele, Tumolo, Mr, Serio, Francesca, Romanazzi, V, Pignata, C, and Schilirò, T.

Subjects
Male, Reproducibility of Result, Environmental Exposure, Health Survey, Motor Activity, Reliability, Food-frequency questionnaire, Diet, Health Statu, Feasibility Studie, Italy, Parent, Air Pollution, Indoor, Surveys and Questionnaires, Female, Repeatability, Child, Children, Environmental Monitoring, Human
Abstract

The MAPEC-Life project aims to study the biological effects of early exposure to air pollutants on the oral mucosa cells of school-age children in five Italian cities. A questionnaire was created to evaluate the association between outdoor and indoor airborne pollutants, lifestyle, diet and biomarker effects. The feasibility and reliability of the questionnaire were evaluated.

Published
2015

13. Incidence and trends of childhood Type 1 diabetes worldwide 1990–1999

Author

THE DIAMOND PROJECT GROUP, BESSAOUD K, BOUDRAA G, DE ROPOLO MM, DE SEREDAY M, MARTI ML, MOSER M, LAPERTOSA S, DAMIANO M, VERGE C, HOWARD N, SCHOBER E, JORDAN O, WEETS I, GORUS F, COECKELBERGHS M, ROOMAN R, VAN GAAL L, FRANCO LJ, FERREIRA SRG, LISBOA HPK, KURTZ LA, GRAEBIN R, KUTZKE L, RODRIGES C, SAVOVA R, CHRISTOV V, IOTOVA V, TZANEVA V, PACAUD D, TOTH E, TAN MH, CARRASCO E, PEREZ F, ZE Y, BO Y, CHEN S, FU L, DENG L, SHEN S, TENG K, WANG C, JIAN H, JU J, YAN C, DENG Y, LI C, ZHANG Y, LIU Y, LONG X, ZHEN Z, SUN Z, WANG B, WONG G, ORREGO OV, ASCHNER P, DIAZ DIAZ O, DE ACOSTA OM, CINEK O, VAVRINEC J, OLSEN BS, SVENDSEN AJ, KREUTZFELDT J, LUND E, TULL ES, SELMAN GEARA A, ALMONTE AS, PODAR T, TUOMILEHTO J, KARVONEN M, NOTKOLA IL, MOLTCHANOVA E, TASKINEN O, LEVY MARCHAL C, CZERNICHOW P, KOCAVA M, NEU A, EHEHALT S, ROSENBAUER J, GIANI G, ICKS A, BARTSOCAS C, VAZEOU A, SOLTESZ G, LARON Z, GORDON O, ALBAG Y, SHAMIS I, PURRELLO F, ARPI M, FICHERA G, MANCUSO M, LUCENTI C, CHIUMELLO G, BRUNO G, PAGANO G, SONGINI M, CASU A, MARINARO A, FRONGIA P, ZEDDA MA, MILIA A, TENCONI MT, POZZILLI P, VISALLI N, SEBASTIANI L, MARIETTI G, BUZZETTI R, CHERUBINI V, OKUNO A, HARADA S, MATSUURA N, MIKI E, MIYAMOTO S, SASAKI N, MIMURA G, SHALTOUT A, QABAZRD M, AL KHAWARI M, BRIGIS G, DZIVITE I, KADIKI O, URBONAITE B, DE BEAUFORT C, GAREEBOO H, RUEDA OA, REESER M, ELLIOTT R, SCOTT R, WILLIS J, DARLOW B, JONER G, RAFIQUE G, JAWAD F, JIMENEZ J, PALACIOS CM, CANETE F, VERA J, ALMIRON R, BENITEZ GE, ESPINOLA CS, SECLEN S, WOZNICKA D, SZYBINSKI Z, PLACZKIEWICZ E, JAROSZ CHOBOT P, MENEZES C, PINA EA, RUAS MMA, RODRIGUES FJC, ABREU S, IONESCU TIRGOVISTE C, SHUBNIKOV E, MICHALKOVA D, BARK L, HLAVA P, MIKULECKY M, KRZISNIK C, BATTELINO T, URSIC NB, KOTNIK P, KO KW, CASTELL C, GODAY A, MAGZOUB M, DAHLQUIST G, SCHOENLE E, NAGATI K, KHALIFA FB, BURDEN A, RAYMOND N, MILLWARD BA, ZHAO H, PATTERSON CC, CARSON D, HADDEN D, SMAIL P, MCSPORRAN B, WAUGH N, BINGLEY P, MCKINNEY PA, FELTBOWER RG, BODANSKY HJ, CAMPBELL F, LAPORTE RE, LIBMAN I, ROSEMAN J, RAHMAN SMA, DE LLADO TF, LIPTON R, JORGE AM, GUNCZLER P, LANES R., DEVOTI, Gabriele, THE DIAMOND PROJECT, Group, Bessaoud, K, Boudraa, G, DE ROPOLO, Mm, DE SEREDAY, M, Marti, Ml, Moser, M, Lapertosa, S, Damiano, M, Verge, C, Howard, N, Schober, E, Jordan, O, Weets, I, Gorus, F, Coeckelberghs, M, Rooman, R, VAN GAAL, L, Franco, Lj, Ferreira, Srg, Lisboa, Hpk, Kurtz, La, Graebin, R, Kutzke, L, Rodriges, C, Savova, R, Christov, V, Iotova, V, Tzaneva, V, Pacaud, D, Toth, E, Tan, Mh, Carrasco, E, Perez, F, Ze, Y, Bo, Y, Chen, S, Fu, L, Deng, L, Shen, S, Teng, K, Wang, C, Jian, H, Ju, J, Yan, C, Deng, Y, Li, C, Zhang, Y, Liu, Y, Long, X, Zhen, Z, Sun, Z, Wang, B, Wong, G, Orrego, Ov, Aschner, P, DIAZ DIAZ, O, DE ACOSTA, Om, Cinek, O, Vavrinec, J, Olsen, B, Svendsen, Aj, Kreutzfeldt, J, Lund, E, Tull, E, SELMAN GEARA, A, Almonte, A, Podar, T, Tuomilehto, J, Karvonen, M, Notkola, Il, Moltchanova, E, Taskinen, O, LEVY MARCHAL, C, Czernichow, P, Kocava, M, Neu, A, Ehehalt, S, Rosenbauer, J, Giani, G, Icks, A, Bartsocas, C, Vazeou, A, Soltesz, G, Laron, Z, Gordon, O, Albag, Y, Shamis, I, Purrello, F, Arpi, M, Fichera, G, Mancuso, M, Lucenti, C, Chiumello, G, Bruno, G, Pagano, G, Songini, M, Casu, A, Marinaro, A, Frongia, P, Zedda, Ma, Milia, A, Tenconi, Mt, Devoti, Gabriele, Pozzilli, P, Visalli, N, Sebastiani, L, Marietti, G, Buzzetti, R, Cherubini, V, Okuno, A, Harada, S, Matsuura, N, Miki, E, Miyamoto, S, Sasaki, N, Mimura, G, Shaltout, A, Qabazrd, M, AL KHAWARI, M, Brigis, G, Dzivite, I, Kadiki, O, Urbonaite, B, DE BEAUFORT, C, Gareeboo, H, Rueda, Oa, Reeser, M, Elliott, R, Scott, R, Willis, J, Darlow, B, Joner, G, Rafique, G, Jawad, F, Jimenez, J, Palacios, Cm, Canete, F, Vera, J, Almiron, R, Benitez, Ge, Espinola, C, Seclen, S, Woznicka, D, Szybinski, Z, Placzkiewicz, E, JAROSZ CHOBOT, P, Menezes, C, Pina, Ea, Ruas, Mma, Rodrigues, Fjc, Abreu, S, IONESCU TIRGOVISTE, C, Shubnikov, E, Michalkova, D, Bark, L, Hlava, P, Mikulecky, M, Krzisnik, C, Battelino, T, Ursic, Nb, Kotnik, P, Ko, Kw, Castell, C, Goday, A, Magzoub, M, Dahlquist, G, Schoenle, E, Nagati, K, Khalifa, Fb, Burden, A, Raymond, N, Millward, Ba, Zhao, H, Patterson, Cc, Carson, D, Hadden, D, Smail, P, Mcsporran, B, Waugh, N, Bingley, P, Mckinney, Pa, Feltbower, Rg, Bodansky, Hj, Campbell, F, Laporte, Re, Libman, I, Roseman, J, Rahman, Sma, DE LLADO, Tf, Lipton, R, Jorge, Am, Gunczler, P, and Lanes, R.

Subjects
Male, Adolescent, type 1 diabetes, Incidence, Endocrinology, Diabetes and Metabolism, Infant, Newborn, Infant, Global Health, World Health Organization, trend, Diabetes Mellitus, Type 1, Endocrinology, Child, Preschool, geographical distribution, incidence, Internal Medicine, Humans, epidemiology, Female, Child
Abstract

Aims. To examine incidence and trends of Type 1 diabetes worldwide for the period 1990–1999. Methods. The incidence of Type 1 diabetes (per 100000/year) was analysed in children aged ≤ 14 years from 114 populations in 112 centres in 57 countries. Trends in the incidence of Type 1 diabetes were analysed by fitting Poisson regression models to the dataset. Results. A total of 43013 cases were diagnosed in the study populations of 84 million children. The age-adjusted incidence of Type 1 diabetes among 112 centres (114 populations) varied from 0.1 per 100000/year in China and Venezuela to 40.9 per 100000/year in Finland. The average annual increase in incidence calculated from 103 centres was 2.8% (95% CI 2.4–3.2%). During the years 1990–1994, this increase was 2.4% (95% CI 1.3–3.4%) and during the second study period of 1995–1999 it was slightly higher at 3.4% (95% CI 2.7– 4.3%). The trends estimated for continents showed statistically significant increases all over the world (4.0% in Asia, 3.2% in Europe and 5.3% in North America), except in Central America and the West Indies where the trend was a decrease of 3.6%. Only among the European populations did the trend in incidence diminish with age. Conclusions. The rising incidence of Type 1 diabetes globally suggests the need for continuous monitoring of incidence by using standardized methods in order to plan or assess prevention strategies.

Published
2006
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14. Birth order and childhood type 1 diabetes risk:a pooled analysis of 31 observational studies

Author

Cardwell, Chris R., Stene, Lars C., Joner, Geir, Bulsara, Max K., Cinek, Ondrej, Rosenbauer, Joachim, Ludvigsson, Johnny, Svensson, Jannet, Goldacre, Michael J., Waldhoer, Thomas, Jarosz-Chobot, Przemyslawa, Gimeno, Suely G. A., Chuang, Lee-Ming, Roberts, Christine L., Parslow, Roger C., Wadsworth, Emma J. K., Chetwynd, Amanda, Brigis, Girts, Urbonaite, Brone, Sipetic, Sandra, Schober, Edith, Devoti, Gabriele, Ionescu-Tirgoviste, Constantin, de Beaufort, Carine E., Stoyanov, Denka, Buschard, Karsten, Radon, Katja, Glatthaar, Christopher, Patterson, Chris C., Cardwell, Chris R., Stene, Lars C., Joner, Geir, Bulsara, Max K., Cinek, Ondrej, Rosenbauer, Joachim, Ludvigsson, Johnny, Svensson, Jannet, Goldacre, Michael J., Waldhoer, Thomas, Jarosz-Chobot, Przemyslawa, Gimeno, Suely G. A., Chuang, Lee-Ming, Roberts, Christine L., Parslow, Roger C., Wadsworth, Emma J. K., Chetwynd, Amanda, Brigis, Girts, Urbonaite, Brone, Sipetic, Sandra, Schober, Edith, Devoti, Gabriele, Ionescu-Tirgoviste, Constantin, de Beaufort, Carine E., Stoyanov, Denka, Buschard, Karsten, Radon, Katja, Glatthaar, Christopher, and Patterson, Chris C.

Abstract

Background The incidence rates of childhood onset type 1 diabetes are almost universally increasing across the globe but the aetiology of the disease remains largely unknown. We investigated whether birth order is associated with the risk of childhood diabetes by performing a pooled analysis of previous studies. Methods Relevant studies published before January 2010 were identified from MEDLINE, Web of Science and EMBASE. Authors of studies provided individual patient data or conducted pre-specified analyses. Meta-analysis techniques were used to derive combined odds ratios (ORs), before and after adjustment for confounders, and investigate heterogeneity. Results Data were available for 6 cohort and 25 case-control studies, including 11 955 cases of type 1 diabetes. Overall, there was no evidence of an association prior to adjustment for confounders. After adjustment for maternal age at birth and other confounders, a reduction in the risk of diabetes in second- or later born children became apparent [fully adjusted OR = 0.90 95% confidence interval (CI) 0.83-0.98; P = 0.02] but this association varied markedly between studies (I-2 = 67%). An a priori subgroup analysis showed that the association was stronger and more consistent in children < 5 years of age (n = 25 studies, maternal age adjusted OR = 0.84 95% CI 0.75, 0.93; I-2 = 23%). Conclusion Although the association varied between studies, there was some evidence of a lower risk of childhood onset type 1 diabetes with increasing birth order, particularly in children aged < 5 years. This finding could reflect increased exposure to infections in early life in later born children.

Published
2011

15. Maternal age at birth and childhood type 1 diabetes:a pooled analysis of 30 observational studies

Author

Cardwell, Chris R., Stene, Lars C., Joner, Geir, Bulsara, Max K., Cinek, Ondrej, Rosenbauer, Joachim, Ludvigsson, Johnny, Jane, Mireia, Svensson, Jannet, Goldacre, Michael J., Waldhoer, Thomas, Jarosz-Chobot, Przemyslawa, Gimeno, Suely G. A., Chuang, Lee-Ming, Parslow, Roger C., Wadsworth, Emma J. K., Chetwynd, Amanda, Pozzilli, Paolo, Brigis, Girts, Urbonaite, Brone, Sipetic, Sandra, Schober, Edith, Devoti, Gabriele, Ionescu-Tirgoviste, Constantin, de Beaufort, Carine E., Stoyanov, Denka, Buschard, Karsten, Patterson, Chris C., Cardwell, Chris R., Stene, Lars C., Joner, Geir, Bulsara, Max K., Cinek, Ondrej, Rosenbauer, Joachim, Ludvigsson, Johnny, Jane, Mireia, Svensson, Jannet, Goldacre, Michael J., Waldhoer, Thomas, Jarosz-Chobot, Przemyslawa, Gimeno, Suely G. A., Chuang, Lee-Ming, Parslow, Roger C., Wadsworth, Emma J. K., Chetwynd, Amanda, Pozzilli, Paolo, Brigis, Girts, Urbonaite, Brone, Sipetic, Sandra, Schober, Edith, Devoti, Gabriele, Ionescu-Tirgoviste, Constantin, de Beaufort, Carine E., Stoyanov, Denka, Buschard, Karsten, and Patterson, Chris C.

Abstract

OBJECTIVE-The aim if the study was to investigate whether children born to older mothers have an increased risk of type 1 diabetes by performing a pooled analysis of previous studies using individual patient data to adjust for recognized confounders. RESEARCH DESIGN AND METHODS-Relevant studies published before June 2009 were identified from MEDLINE, Web of Science, and EMBASE. Authors of studies were contacted and asked to provide individual patient data or conduct prespecified analyses. Risk estimates of type 1 diabetes by maternal age were calculated for each study, before and after adjustment for potential confounders. Meta-analysis techniques were used to derive combined odds ratios and to investigate heterogeneity among studies. RESULTS-Data were available for 5 cohort and 25 case-control studies, including 14,724 cases of type 1 diabetes. Overall, there was, on average, a 5% (95% CI 2-9) increase in childhood type 1 diabetes odds per 5-year increase in maternal age (P = 0.006), but there was heterogeneity among studies (heterogeneity I-2 = 70%). In studies with a low risk of bias, there was a more marked increase in diabetes odds of 10% per 5-year increase in maternal age. Adjustments for potential confounders little altered these estimates. CONCLUSIONS-There was evidence of a weak but significant linear increase in the risk of childhood type 1 diabetes across the range of maternal ages, but the magnitude of association varied between studies. A very small percentage of the increase in the incidence of childhood type 1 diabetes in recent years could be explained by increases in maternal age. Diabetes 59:486-494, 2010

Published
2010

16. Breast-feeding and childhood-onset type 1 diabetes: a pooled analysis of individual participant data from 43 observational studies

Author

Cardwell, Chris R, Stene, Lars C, Ludvigsson, Johnny, Rosenbauer, Joachim, Cinek, Ondrej, Svensson, Jannet, Perez-Bravo, Francisco, Memon, Anjum, Gimeno, Suely G, Wadsworth, Emma J K, Strotmeyer, Elsa S, Goldacre, Michael J, Radon, Katja, Chuang, Lee-Ming, Parslow, Roger C, Chetwynd, Amanda, Karavanaki, Kyriaki, Brigis, Girts, Pozzilli, Paolo, Urbonaite, Brone, Schober, Edith, Devoti, Gabriele, Sipetic, Sandra, Joner, Geir, Ionescu-Tirgoviste, Constantin, de Beaufort, Carine E, Harrild, Kirsten, Benson, Victoria, Savilahti, Erkki, Ponsonby, Anne-Louise, Salem, Mona, Rabiei, Samira, Patterson, Chris C, Cardwell, Cr, Stene, Lc, Ludvigsson, J, Rosenbauer, J, Cinek, O, Svensson, J, Perez Bravo, F, Memon, A, Gimeno, Sg, Wadsworth, Ej, Strotmeyer, E, Goldacre, Mj, Radon, K, Chuang, Lm, Parslow, Rc, Chetwynd, A, Karavanaki, K, Brigis, G, Pozzilli, P, Urbonaité, B, Schober, E, Devoti, Gabriele, Sipetic, S, Joner, G, Ionescu Tirgoviste, C, de Beaufort, Ce, Harrild, K, Benson, V, Savilahti, E, Ponsoney, Al, Salem, M, Rabiei, S, and Patterson, C. C.

Subjects
Medicin och hälsovetenskap, Multidisciplinaire, généralités & autres [D99] [Sciences de la santé humaine], type 1 diabetes, breast-feeding, Medical and Health Sciences, observational studies, Multidisciplinary, general & others [D99] [Human health sciences], childhood
Abstract

OBJECTIVE-To investigate if there is a reduced risk of type 1 diabetes in children breastfed or exclusively breastfed by performing a pooled analysis with adjustment for recognized confounders. less thanbrgreater than less thanbrgreater thanRESEARCH DESIGN AND METHODS-Relevant studies were identified from literature searches using MEDLINE, Web of Science, and EMBASE. Authors of relevant studies were asked to provide individual participant data or conduct prespecified analyses. Meta-analysis techniques were used to combine odds ratios (ORs) and investigate heterogeneity between studies. less thanbrgreater than less thanbrgreater thanRESULTS-Data were available from 43 studies including 9,874 patients with type 1 diabetes. Overall, there was a reduction in the risk of diabetes after exclusive breast-feeding for andgt;2 weeks (20 studies; OR = 0.75, 95% CI 0.64-0.88), the association after exclusive breast-feeding for andgt;3 months was weaker (30 studies; OR = 0.87, 95% CI 0.75-1.00), and no association was observed after (nonexclusive) breast-feeding for andgt;2 weeks (28 studies; OR = 0.93, 95% CI 0.81-1.07) or andgt;3 months (29 studies; OR = 0.88, 95% CI 0.78-1.00). These associations were all subject to marked heterogeneity (I-2 = 58, 76, 54, and 68%, respectively). In studies with lower risk of bias, the reduced risk after exclusive breast-feeding for andgt;2 weeks remained (12 studies; OR = 0.86, 95% CI 0.75-0.99), and heterogeneity was reduced (I-2 = 0%). Adjustments for potential confounders altered these estimates very little. less thanbrgreater than less thanbrgreater thanCONCLUSIONS-The pooled analysis suggests weak protective associations between exclusive breast-feeding and type 1 diabetes risk. However, these findings are difficult to interpret because of the marked variation in effect and possible biases (particularly recall bias) inherent in the included studies. Funding Agencies|National Institutes of Health|R01-DK-46498R01-DK-42316|Chinese Foundation of Health||Department of Health, Executive Yuan, Republic of China|DOH91-TD1167|Ministry for Science and Technology of the Republic of Serbia|175042|German Research Foundation|HE 234/1-1|Research Council of Norway|148359/330

Published
2012

17. Nuovi indirizzi per la prevenzione delle malattie cardiocircolatorie

Author

TENCONI MT, GRUPPO DI LAVORO SITI PER LA PREVENZIONE DELLE MALATTIE CARDIOVASCOLARI E. DEL DIABETE, DEVOTI, Gabriele, Tenconi, Mt, GRUPPO DI LAVORO SITI PER LA PREVENZIONE DELLE MALATTIE CARDIOVASCOLARI E., DEL DIABETE, and Devoti, Gabriele

Abstract

Le malattie cardiovascolari rappresentano attualmente la prima causa di morte e di disabilità nel nostro paese. Come fattori di rischio modificabili sono stati indicati l’elevata colesterolemia LDL, l’ipertensione, il fumo di tabacco, il diabete mellito e/o la sindrome metabolica e la sedentarietà, la cui prevalenza può considerarsi elevata tra la popolazione adulta. La prevenzione deve iniziare precocemente con il coinvolgimento della popolazione per l’acquisizione di uno stile di vita sano nelle comunità scolastiche e lavorative e con interventi di promozione della salute. È inoltre consigliato lo screening dei soggetti “a rischio” tra la popolazione mediante l’utilizzazione della “carta del rischio cardiovascolare” e il trattamento delle condizioni di rischio da parte degli operatori dei servizi sanitari di base a cui la popolazione fa riferimento.

Published
2008

18. L'abitudine al fumo tra gli studenti dai 13 ai 18 anni di età in Lombardia

Author

S. SACCO, M. BONFANTI, F. RONCAROLO, L. MACCHI, A. PAVAN, M.T. TENCONI, DEVOTI, Gabriele, S., Sacco, Devoti, Gabriele, M., Bonfanti, F., Roncarolo, L., Macchi, A., Pavan, and Tenconi, M. T.

Subjects
adolescenti, scuola, fumo di tabacco
Abstract

Obiettivo: descrivere la prevalenza dell’abitudine al fumo tra gli studenti lombardi dai 13 ai 18 anni di età e valutare alcuni determinanti a essa correlati. Disegno: la rilevazione dei dati è stata effettuata mediante questionari anonimi, somministrati all’inizio dell’anno scolastico 2005-2006. Setting: lo studio è stato effettuato su 3593 classi di terza nella scuola secondaria di primo grado e su 2893 classi di seconda e di quinta nella scuola secondaria di secondo grado, campionate tra tutte le scuole della Lombardia. Partecipanti: lo studio ha interessato 11494 studenti lombardi di 13, 15 e 18 anni. Outcome principali: la prevalenza di fumatori abituali tra gli studenti delle tre età considerate è rispettivamente pari a 6%, 26,5% e 33,2%. Risultati: gli alunni fumatori dichiarano in percentuale più elevata di avere uno scarso rendimento scolastico e di ricevere più di 15 euro come mancia settimanale. Il numero di fumatori tra i componenti della famiglia e gli amici appare sempre più elevato per gli studenti che fumano. Il tasso di disoccupazione del padre risulta maggiore tra gli scolari fumatori, mentre, per quanto riguarda la condizione lavorativa della madre, si verifica la situazione opposta. Entrambi i genitori degli alunni che fumano tendono ad avere un livello d’istruzione inferiore. Conclusione: una sorveglianza regionale organizzata e sistematica evidenzierebbe alcune caratteristiche dell’abitudine al fumo tra gli studenti adolescenti utili per impostare programmi di educazione sanitaria e valutare la ricaduta della prevenzione già in atto. Inoltre, essa potrebbe rivestire il ruolo di un intervento di sensibilizzazione verso il problema.

Published
2008

19. Sorveglianza dell’abitudine al fumo nell’età evolutiva

Author

DEVOTI, Gabriele, TENCONI MT, BONFANTI M, RONCAROLO F, MACCHI L., Devoti, Gabriele, Tenconi, Mt, Bonfanti, M, Roncarolo, F, and Macchi, L.

Subjects
studenti, fumo di tabacco
Abstract

La Regione Lombardia ha attuato dal 2005 un programma di sorveglianza dell’abitudine al fumo tra i giovani in collaborazione con la Sezione di Igiene del Dipartimento di Medicina Preventiva, Occupazionale e di Comunità dell’Università di Pavia. Il programma prevede il rilievo dell’abitudine al fumo a cadenza quadriennale mediante la somministrazione di un questionario a un campione rappresentativo di studenti di III media inferiore, II e V media superiore della Regione Lombardia. A tale scopo all’inizio dell’anno scolastico 2005-2006 sono stati reclutati 12000 studenti delle classi interessate mediante un campionamento a “cluster”, utilizzando i dati forniti dal Ministero dell’Istruzione (110 classi di III media, 229 di II superiore e 262 di V superiore), scelte a caso tra le scuole della provincia di ciascuna Azienda Sanitaria Locale in base alla percentuale di studenti presenti nel territorio e per le superiori ulteriormente suddiviso in base alla tipologia di Istituto. La somministrazione del questionario autocompilato è stata eseguita a scuola dagli operatori sanitari di tutte le 15 Aziende Sanitarie della Lombardia. Hanno partecipato all’indagine 11470 studenti, 6050 maschi e 5420 femmine (2478 di III media inferiore, 4462 di II superiore e 4530 di V superiore). La prevalenza di fumatori abituali (almeno 1 sigaretta alla settimana) in III media inferiore è risultata del 6% (per i maschi 6,6% e per le femmine 5,4%). Il numero medio di sigarette fumate alla settimana è di 9 sigarette; il 43,4% dei ragazzi fuma ogni giorno. In II media superiore la prevalenza di fumatori aumenta considerevolmente, raggiungendo il 26,5% (M=26,9% e F=26,3%) con una media di circa 8 sigarette fumate al giorno; l’80% fuma tutti i giorni. In V superiore la prevalenza aumenta ulteriormente fino al 33,2% (33,9% M e 32,7% F). Il numero medio di sigarette fumate al giorno è sovrapponibile a quello degli studenti di II e l’84,4% dei fumatori asserisce di fumare tutti i giorni.

Published
2006

21. Diabetes Incidence in 0- to 14-Year Age-Group in Italy

Author

CARLE F, GESUITA R, BRUNO G, COPPA GV, FALORNI A, LORINI R, MARTINUCCI ME, POZZILLI P, PRISCO F, SONGINI M, TENCONI MT, CHERUBINI V, THE RIDI STUDY GROUP, PIFFER S, FRANCHINI S, BIANCHI L, CERUTTI F, MERLETTI F, PAGANO G, COTELLESSA M, MINICUCCI L, BARBIERI P, D’ANNUNZIO G, BAZZANO S, TONI S, REALI MS, MEDICI A, IUGHETTI L, PREDIERI B, BALLI F, VISALLI N, SEBASTIANI L, MARIETTI G, SANTEUSANIO F, DE GIORGI G, SANTILLI E, IANNILLI A, PINELLI A, MASCIOLI G, ALTOBELLI E, CHIARELLI F, TUMINI S, IAFUSCO D, DE FELICE E, INGENITO N, CASU A, FRONGIA P, MARINARO A., DEVOTI, Gabriele, Carle, F, Gesuita, R, Bruno, G, Coppa, Gv, Falorni, A, Lorini, R, Martinucci, Me, Pozzilli, P, Prisco, F, Songini, M, Tenconi, Mt, Cherubini, V, THE RIDI STUDY, Group, Piffer, S, Franchini, S, Bianchi, L, Cerutti, F, Merletti, F, Pagano, G, Cotellessa, M, Minicucci, L, Barbieri, P, Devoti, Gabriele, D’Annunzio, G, Bazzano, S, Toni, S, Reali, M, Medici, A, Iughetti, L, Predieri, B, Balli, F, Visalli, N, Sebastiani, L, Marietti, G, Santeusanio, F, DE GIORGI, G, Santilli, E, Iannilli, A, Pinelli, A, Mascioli, G, Altobelli, E, Chiarelli, F, Tumini, S, Iafusco, D, DE FELICE, E, Ingenito, N, Casu, A, Frongia, P, and Marinaro, A.

Subjects
incidence, registry, Type 1 diabetes mellitu
Abstract

Objective. The Registry for Type 1 Diabetes Mellitus in Italy (RIDI) Study Group was established to coordinate the registries of type 1 diabetes in Italy. This report is based on 3,606 children younger than 15 years diagnosed with type 1 diabetes and prospectively registered during 1990-1999 by nine centers, covering > 35% of the Italian population. Research design and methods. Registries were pooled in four geographic macro-areas: north, central, south and insular. The completeness of registration was assessed by the capture-recapture method. Poisson regression analysis was used to evaluate temporal trend in incidence. Results. Large variation in incidence were confirmed not only between Sardegna and the mainland but also among peninsular areas. In Sardegna, there was an excess of boys (the boy-to-girl incidence ratio was 1.4). The overall incidence showed average increases of 3.6% (p

Published
2004

27. Incidence variation and trends of childhood type 1 diabetes in ITALY

Author

CHERUBINI V, CARLE F, GESUITA R, PINELLI A, KANTAR A, CERUTTI F, PAGANO G, BRUNO G, MAZZELLA M, BARBIERI P, LORINI R, DANNUNZIO G, TENCONI MT, FRONGIA P, CASU A, SONGINI M, VISALLI N, MARIETTI G, POZZILLI P, FALORNI A, PICCHIO MI, DE GIORGI G, PRISCO F, IAFUSCO D, INGENITO N, RIDI CO ORDINATING CENTRE, UNIVERSITY OF ANCONA, ITALY, DEVOTI, Gabriele, Cherubini, V, Carle, F, Gesuita, R, Pinelli, A, Kantar, A, Cerutti, F, Pagano, G, Bruno, G, Mazzella, M, Barbieri, P, Lorini, R, Devoti, G, D’Annunzio, G, Tenconi, Mt, Frongia, P, Casu, A, Songini, M, Visalli, N, Marietti, G, Pozzilli, P, Falorni, A, Picchio, Ml, De Giorgi, G, Prisco, F, Iafusco, Dario, Ingenito, N, ordinating Centre, RIDI C. o., University of, Ancona, Italy, Devoti, Gabriele, Dannunzio, G, Picchio, Mi, DE GIORGI, G, Iafusco, D, RIDI CO ORDINATING, Centre, and UNIVERSITY OF, Ancona

Published
2000

30. Incidence of Childhood Type 1 Diabetes Worlwide

Author

KARVONEN M, VIIK KAJANDER M, MOLTCHANOVA E, LIBMAN I, LAPORTE R, TUOMILEHTO J, THE DIABETES MONDIALE DIAMOND PROJECT GROUP, BESSAOUD K, BOUDRAA G, DE ROPOLO MM, DE SEREDAY M, MARTI ML, MOSER M, LAPERTOSA S, DAMIANO M, VERGE C, HOWARD N, SCHOBER E, JORDAN O, WEETS I, GORUS F, COECKELBERGHS M, ROOMAN R, VAN GAAL L, FRANCO LJ, FERREIRA SRG, LISBOA HPK, KURTZ LA, GRAEBIN R, KUTZKE L, RODRIGES C, SAVOVA R, CHRISTOV V, IOTOVA V, TZANEVA V, PACAUD D, TOTH E, TAN MH, CARRASCO E, PEREZ F, ZE Y, BO Y, CHEN S, FU L, DENG L, SHEN S, TENG K, WANG C, JIAN H, JU J, YAN C, DENG Y, LI C, ZHANG Y, LIU Y, LONG X, ZHEN Z, SUN Z, WANG B, WONG G, ORREGO OV, ASCHNER P, DIAZ DIAZ O, DE ACOSTA OM, CINEK O, VAVRINEC J, OLSEN BS, SVENDSEN AJ, KREUTZFELDT J, LUND E, TULL ES, SELMAN GEARA A, ALMONTE AS, PODAR T, NOTKOLA IL, TASKINEN O, LEVY MARCHAL C, CZERNICHOW P, KOCAVA M, NEU A, EHEHALT S, ROSENBAUER J, GIANI G, ICKS A, BARTSOCAS C, VAZEOU A, SOLTESZ G, LARON Z, GORDON O, ALBAG Y, SHAMIS I, PURRELLO F, ARPI M, FICHERA G, MANCUSO M, LUCENTI C, CHIUMELLO G, BRUNO G, PAGANO G, SONGINI M, CASU A, MARINARO A, FRONGIA P, ZEDDA MA, MILIA A, TENCONI MT, POZZILLI P, VISALLI N, SEBASTIANI L, MARIETTI G, BUZZETTI R, CHERUBINI V, OKUNO A, HARADA S, MATSUURA N, MIKI E, MIYAMOTO S, SASAKI N, MIMURA G, SHALTOUT A, AL KHAWARI M, BRIGIS G, DZIVITE I, KADIKI O, URBONAITE B, DE BEAUFORT C, GAREEBOO H, RUEDA OA, REESER M, ELLIOTT R, SCOTT R, WILLIS J, DARLOW B, JONER G, RAFIQUE G, JIMENEZ J, PALACIOS CM, CANETE F, VERA J, ALMIRON R, BENITEZ GE, ESPINOLA CS, SECLEN S, WOZNICKA D, SZYBINSKI Z, PLACZKIEWICZ E, RUAS MMA, RODRIGUES FJC, ABREU S, IONESCU TIRGOVISTE C, SHUBNIKOV E, MICHALKOVA D, BARK L, HLAVA P, MIKULECKY M, KRZISNIK C, BATTELINO T, URSIC NB, KOTNIK P, KO KW, CASTELL C, DAHLQUIST G, SCHOENLE E, NAGATI K, KHALIFA FB, BURDEN A, RAYMOND N, MILLWARD BA, ZHAO H, PATTERSON CC, CARSON D, HADDEN D, SMAIL P, MCSPORRAN B, WAUGH N, BINGLEY P, MCKINNEY PA, FELTBOWER RG, BODANSKY HJ, CAMPBELL F, ROSEMAN J., DEVOTI, Gabriele, Karvonen, M, VIIK KAJANDER, M, Moltchanova, E, Libman, I, Laporte, R, Tuomilehto, J, THE DIABETES MONDIALE DIAMOND PROJECT, Group, Bessaoud, K, Boudraa, G, DE ROPOLO, Mm, DE SEREDAY, M, Marti, Ml, Moser, M, Lapertosa, S, Damiano, M, Verge, C, Howard, N, Schober, E, Jordan, O, Weets, I, Gorus, F, Coeckelberghs, M, Rooman, R, VAN GAAL, L, Franco, Lj, Ferreira, Srg, Lisboa, Hpk, Kurtz, La, Graebin, R, Kutzke, L, Rodriges, C, Savova, R, Christov, V, Iotova, V, Tzaneva, V, Pacaud, D, Toth, E, Tan, Mh, Carrasco, E, Perez, F, Ze, Y, Bo, Y, Chen, S, Fu, L, Deng, L, Shen, S, Teng, K, Wang, C, Jian, H, Ju, J, Yan, C, Deng, Y, Li, C, Zhang, Y, Liu, Y, Long, X, Zhen, Z, Sun, Z, Wang, B, Wong, G, Orrego, Ov, Aschner, P, DIAZ DIAZ, O, DE ACOSTA, Om, Cinek, O, Vavrinec, J, Olsen, B, Svendsen, Aj, Kreutzfeldt, J, Lund, E, Tull, E, SELMAN GEARA, A, Almonte, A, Podar, T, Notkola, Il, Taskinen, O, LEVY MARCHAL, C, Czernichow, P, Kocava, M, Neu, A, Ehehalt, S, Rosenbauer, J, Giani, G, Icks, A, Bartsocas, C, Vazeou, A, Soltesz, G, Laron, Z, Gordon, O, Albag, Y, Shamis, I, Purrello, F, Arpi, M, Fichera, G, Mancuso, M, Lucenti, C, Chiumello, G, Bruno, G, Pagano, G, Songini, M, Casu, A, Marinaro, A, Frongia, P, Zedda, Ma, Milia, A, Tenconi, Mt, Devoti, Gabriele, Pozzilli, P, Visalli, N, Sebastiani, L, Marietti, G, Buzzetti, R, Cherubini, V, Okuno, A, Harada, S, Matsuura, N, Miki, E, Miyamoto, S, Sasaki, N, Mimura, G, Shaltout, A, AL KHAWARI, M, Brigis, G, Dzivite, I, Kadiki, O, Urbonaite, B, DE BEAUFORT, C, Gareeboo, H, Rueda, Oa, Reeser, M, Elliott, R, Scott, R, Willis, J, Darlow, B, Joner, G, Rafique, G, Jimenez, J, Palacios, Cm, Canete, F, Vera, J, Almiron, R, Benitez, Ge, Espinola, C, Seclen, S, Woznicka, D, Szybinski, Z, Placzkiewicz, E, Ruas, Mma, Rodrigues, Fjc, Abreu, S, IONESCU TIRGOVISTE, C, Shubnikov, E, Michalkova, D, Bark, L, Hlava, P, Mikulecky, M, Krzisnik, C, Battelino, T, Ursic, Nb, Kotnik, P, Ko, Kw, Castell, C, Dahlquist, G, Schoenle, E, Nagati, K, Khalifa, Fb, Burden, A, Raymond, N, Millward, Ba, Zhao, H, Patterson, Cc, Carson, D, Hadden, D, Smail, P, Mcsporran, B, Waugh, N, Bingley, P, Mckinney, Pa, Feltbower, Rg, Bodansky, Hj, Campbell, F, and Roseman, J.

Published
2000

36. Role of body mass index in the prediction of all cause mortality in over 62000 men and women. The Italian RIFLE Pooling Project

Author

SECCARECCIA F, LANTI M, MENOTTI A, SCANGA M, THE RIFLE RESEARCH GROUP, FARCHI G, CONTI S, MARENCO G, FALCHERO M, FERRARIO M, CESANA GC, TENCONI MT, MUSSI A, DOBRILLA G, DE PETRIS G, ANGELINI GP, OCKOLICSANYI L, TOSO S, AMBROSIO GB, BITTOLO BON G, ALESSANDRINI P, FERUGLIO GA, VANUZZO D, CARULLI N, SALVIOLI GF, GADDI A, D'ADDARO S, ALVISI V, BUZZELLI GP, GIACCHI M, LAURENZI M, SPAGNOLO A, RICCI G, ANTONINI R, ANGELICO F, LALLONI L, ATTILI AF, URBINATI GC, GIAMPAOLI S, MANCINI M, PANICO S, FARINARO E, ALBANO O, MISCIAGNA G, MUNTONI S, STABILINI L, AVELLONE G, DI GARBO G., DEVOTI, Gabriele, Seccareccia, F, Lanti, M, Menotti, A, Scanga, M, THE RIFLE RESEARCH, Group, Farchi, G, Conti, S, Marenco, G, Falchero, M, Ferrario, M, Cesana, Gc, Tenconi, Mt, Mussi, A, Devoti, Gabriele, Dobrilla, G, DE PETRIS, G, Angelini, Gp, Ockolicsanyi, L, Toso, S, Ambrosio, Gb, BITTOLO BON, G, Alessandrini, P, Feruglio, Ga, Vanuzzo, D, Carulli, N, Salvioli, Gf, Gaddi, A, D'Addaro, S, Alvisi, V, Buzzelli, Gp, Giacchi, M, Laurenzi, M, Spagnolo, A, Ricci, G, Antonini, R, Angelico, F, Lalloni, L, Attili, Af, Urbinati, Gc, Giampaoli, S, Mancini, M, Panico, S, Farinaro, E, Albano, O, Misciagna, G, Muntoni, S, Stabilini, L, Avellone, G, and DI GARBO, G.

Published
1998

40. Electrocardiographic Minnesota Code findings predicting short-term mortality in asymptomatic subjects. The Italian RIFLE Pooling Project (Risk Factors and Life Expectancy)

Author

MENOTTI A, SECCARECCIA F, THE RIFLE RESEARCH GROUP, LANTI M, FARCHI G, CONTI S, DIMA F, SCANGA M, MARENCO G, FALCHERO M, FERRARIO M, CESANA GC, TENCONI MT, LADDOMADA MS, DOBRILLA G, DE PETRIS G, ANGELINI GP, OCKOLICSANYI L, TOSO S, AMBROSIO GB, BITTOLO BON G, ALESSANDRINI P, FERUGLIO GA, VANUZZO D, CARULLI N, SALVIOLI GF, GADDI A, D'ADDATO S, ALVISI V, BUZZELLI GP, GIACCHI M, LAURENZI M, SPAGNOLO A, RICCI G, ANTONINI R, ANGELICO F, LALLONI L, ATTILI AF, URBINATI GC, GIAMPAOLI S, MANCINI M, PANICO S, FARINARO E, ALBANO O, MISCIAGNA G, MUNTONI S, STABILINI L, AVELLONE G, DI GARBO G. ., DEVOTI, Gabriele, Menotti, A, Seccareccia, F, THE RIFLE RESEARCH, Group, Lanti, M, Farchi, G, Conti, S, Dima, F, Scanga, M, Marenco, G, Falchero, M, Ferrario, M, Cesana, Gc, Tenconi, Mt, Laddomada, M, Devoti, Gabriele, Dobrilla, G, DE PETRIS, G, Angelini, Gp, Ockolicsanyi, L, Toso, S, Ambrosio, Gb, BITTOLO BON, G, Alessandrini, P, Feruglio, Ga, Vanuzzo, D, Carulli, N, Salvioli, Gf, Gaddi, A, D'Addato, S, Alvisi, V, Buzzelli, Gp, Giacchi, M, Laurenzi, M, Spagnolo, A, Ricci, G, Antonini, R, Angelico, F, Lalloni, L, Attili, Af, Urbinati, Gc, Giampaoli, S, Mancini, M, Panico, S, Farinaro, E, Albano, O, Misciagna, G, Muntoni, S, Stabilini, L, Avellone, G, and DI GARBO, G. .

Published
1997

42. Syndrome X: prevalence in a large population-based study

Author

LIU J, TREVISAN M, MENOTTI A, THE RIFLE RESEARCH GROUP, LANTI M, FARCHI G, CONTI S, SECCARECCIA F, DIMA F, SCANGA M, MARENCO G, FALCHERO M, FERRARIO M, CESANA GC, TENCONI MT, LADDOMADA MS, DOBRILLA G, DE PETRIS G, ANGELINI GP, OCKOLICSANYI L, TOSO S, AMBROSIO GB, BITTOLO BON G, ALESSANDRINI P, FERUGLIO GA, VANUZZO D, CARULLI N, SALVIOLI GF, GADDI A, D'ADDARO S, ALVISI V, BUZZELLI GP, GIACCHI M, LAURENZI M, SPAGNOLO A, RICCI G, ANTONINI R, ANGELICO F, LALLONI L, ATTILI AF, URBINATI GC, GIAMPAOLI S, MANCINI M, PANICO S, FARINARO E, ALBANO O, MISCIAGNA G, MUNTONI S, STABILINI L, AVELLONE G, DI GARBO G. ., DEVOTI, Gabriele, Liu, J, Trevisan, M, Menotti, A, THE RIFLE RESEARCH, Group, Lanti, M, Farchi, G, Conti, S, Seccareccia, F, Dima, F, Scanga, M, Marenco, G, Falchero, M, Ferrario, M, Cesana, Gc, Tenconi, Mt, Laddomada, M, Devoti, Gabriele, Dobrilla, G, DE PETRIS, G, Angelini, Gp, Ockolicsanyi, L, Toso, S, Ambrosio, Gb, BITTOLO BON, G, Alessandrini, P, Feruglio, Ga, Vanuzzo, D, Carulli, N, Salvioli, Gf, Gaddi, A, D'Addaro, S, Alvisi, V, Buzzelli, Gp, Giacchi, M, Laurenzi, M, Spagnolo, A, Ricci, G, Antonini, R, Angelico, F, Lalloni, L, Attili, Af, Urbinati, Gc, Giampaoli, S, Mancini, M, Panico, S, Farinaro, E, Albano, O, Misciagna, G, Muntoni, S, Stabilini, L, Avellone, G, and DI GARBO, G. .

Published
1997

49. Atherosclerosis precursors in northern italian adolescents

Author

MUSSI A, PELISSERO G, IANNELLO G, MARCHI A, BONCOMPAGNI E, CORSI B, TENCONI M.T., DEVOTI, Gabriele, Mussi, A, Pelissero, G, Iannello, G, Devoti, Gabriele, Marchi, A, Boncompagni, E, Corsi, B, and Tenconi, M. T.

Published
1995

50. Mean levels and distributions of some cardiovascular risk factors in Italy in the 1970's and the 1980's. The Italian RIFLE Pooling Project. Risk Factors and Life Expectancy

Author

MENOTTI A, SECCARECCIA F, LANTI M, THE RIFLE PROJECT RESEARCH GROUP, FARCHI G, CONTI S, DIMA F, SCANGA M, MARENCO G, FALCHERO M, IDEO G, PODDA M, FERRARIO M, CESANA GC, TENCONI MT, MUSSI A, DOBRILLA G, DE PETRIS G, ANGELINI GP, OCKOLICSANYI L, TOSO S, AMBROSIO GB, BITTOLO BON G, ALESSANDRINI P, FERUGLIO GA, VANUZZO D, CARULLI N, SALVIOLI GF, GADDI A, D'ADDARO S, ALVISI V, BUZZELLI GP, GIACCHI M, LAURENZI M, SPAGNOLO A, RICCI G, ANTONINI R, ANGELICO F, LALLONI L, ATTILI AF, URBINATI GC, GIAMPAOLI S, MANCINI M, PANICO S, FARINARO E, ALBANO O, MISCIAGNA G, MUNTONI S, STABILINI L, AVELLONE G, DI GARBO G. ., DEVOTI, Gabriele, Menotti, A, Seccareccia, F, Lanti, M, THE RIFLE PROJECT RESEARCH, Group, Farchi, G, Conti, S, Dima, F, Scanga, M, Marenco, G, Falchero, M, Ideo, G, Podda, M, Ferrario, M, Cesana, Gc, Tenconi, Mt, Mussi, A, Devoti, Gabriele, Dobrilla, G, DE PETRIS, G, Angelini, Gp, Ockolicsanyi, L, Toso, S, Ambrosio, Gb, BITTOLO BON, G, Alessandrini, P, Feruglio, Ga, Vanuzzo, D, Carulli, N, Salvioli, Gf, Gaddi, A, D'Addaro, S, Alvisi, V, Buzzelli, Gp, Giacchi, M, Laurenzi, M, Spagnolo, A, Ricci, G, Antonini, R, Angelico, F, Lalloni, L, Attili, Af, Urbinati, Gc, Giampaoli, S, Mancini, M, Panico, S, Farinaro, E, Albano, O, Misciagna, G, Muntoni, S, Stabilini, L, Avellone, G, and DI GARBO, G. .

Published
1995

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