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1. Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as an antimalarial strategy

2. Arginine catabolism is essential to polymyxin dependence in Acinetobacter baumannii

3. On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity

4. Promising antimalarial hits from phenotypic screens: a review of recently-described multi-stage actives and their modes of action

5. Current and emerging target identification methods for novel antimalarials

6. Integrated metabolomic and transcriptomic analyses of the synergistic effect of polymyxin–rifampicin combination against Pseudomonas aeruginosa

7. Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites

8. Cell biological analysis reveals an essential role for Pfcerli2 in erythrocyte invasion by malaria parasites

9. Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition

10. Comparative metabolomics revealed key pathways associated with the synergistic killing of multidrug-resistant Klebsiella pneumoniae by a bacteriophage-polymyxin combination

11. The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism

12. Targeting malaria parasites with novel derivatives of azithromycin

13. Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway

14. Non‐canonical metabolic pathways in the malaria parasite detected by isotope‐tracing metabolomics

15. Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation

16. Retargeting azithromycin analogues to have dual-modality antimalarial activity

17. Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution

18. Multi-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii

19. CoviRx: A User-Friendly Interface for Systematic Down-Selection of Repurposed Drug Candidates for COVID-19

20. Use of Human Lung Tissue Models for Screening of Drugs against SARS-CoV-2 Infection

21. Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast

22. Red Blood Cell BCL-xL Is Required for Plasmodium falciparum Survival: Insights into Host-Directed Malaria Therapies

24. Polymyxins Bind to the Cell Surface of Unculturable Acinetobacter baumannii and Cause Unique Dependent Resistance

25. Sulfoxide‐Containing Polymer‐Coated Nanoparticles Demonstrate Minimal Protein Fouling and Improved Blood Circulation

26. System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion.

27. Mechanistic Insights From Global Metabolomics Studies into Synergistic Bactericidal Effect of a Polymyxin B Combination With Tamoxifen Against Cystic Fibrosis MDR Pseudomonas aeruginosa

28. Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy

29. Comparative Metabolomics Reveals Key Pathways Associated With the Synergistic Killing of Colistin and Sulbactam Combination Against Multidrug-Resistant Acinetobacter baumannii

30. Comparative Metabolomics and Transcriptomics Reveal Multiple Pathways Associated with Polymyxin Killing in Pseudomonas aeruginosa

31. Dietary fibre reverses adverse post-stroke outcomes in mice via short-chain fatty acids and its sensing receptors GPR41, GPR43 and GPR109A

33. Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy

34. Peroxide Antimalarial Drugs Target Redox Homeostasis in Plasmodium falciparum Infected Red Blood Cells

35. Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition

36. ThePlasmodium falciparumartemisinin resistance-associated protein Kelch 13 is required for formation of normal cytostomes

37. Metabolomes and Lipidomes of the Infective Stages of the Gastrointestinal nematodes, Nippostrongylus brasiliensis and Trichuris muris

38. Measuring Sulforaphane and Its Metabolites in Human Plasma: A High Throughput Method

39. TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei.

40. Metabolic Analyses Revealed Time-Dependent Synergistic Killing by Colistin and Aztreonam Combination Against Multidrug-Resistant Acinetobacter baumannii

41. Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei.

42. Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues.

43. Synergistic Killing of Polymyxin B in Combination With the Antineoplastic Drug Mitotane Against Polymyxin-Susceptible and -Resistant Acinetobacter baumannii: A Metabolomic Study

44. Dynamic Protein Corona of Gold Nanoparticles with an Evolving Morphology

45. Key signaling networks are dysregulated in patients with the adipose tissue disorder, lipedema

46. Mesenteric lymphatic dysfunction promotes insulin resistance and represents a potential treatment target in obesity

47. Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana.

48. Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate

49. Systematic Down-Selection of Repurposed Drug Candidates for COVID-19

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