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The Judd-Ofelt analysis is essential because it indicates the influence of rare earth ion doping on the host matrix in which they are found. In the present work, the results of the optical characterization of zinc-tellurite glasses doped with Yb3+ are presented, varying the concentrations of Tm3+ and Er3+ by means of UVVIS absorption spectroscopy and refractive index measurements. From these results, the Judd-Ofelt parameters were obtained, which indicated a structural modification with the addition of rare earth ions in the tellurite glassy matrix, due to the rearrangement of the glassy structure and the breaking of Te-O bonds. [ABSTRACT FROM AUTHOR]

In this study, we developed an isothermal fluorometric diagnostic method for DNA virus-generating disorders such as Mpox. Our results showed that the release of a large number of protons during multiplex-LAMP markedly lowered the pH level, which transformed the retinoblastoma (Rb) linear ssDNA into i-motifs. Consequently, thiazole orange (TO; a fluorometric probe sensitive to the i-motif) boosted the signal-on fluorescence because of its ability to bind selectively to i-motifs. This multiplex-LAMP/i-motif-TO system enabled simultaneous detection aimed at numerous potential targets with remarkable sensitivity (1.47 pg per mL) and efficiency (30 minutes). Our method is expected to enable DNA-virus-related diseases to be efficiently and accurately assessed. [ABSTRACT FROM AUTHOR]

Water erosion poses a significant threat to more than 50% of agricultural land in the Czech Republic. Maize (Zea mays L.) is particularly susceptible to soil erosion, with the bare soil space between maize rows exposed to erosive agents. Intercropping has emerged as a potential solution to mitigate soil erosion risks in maize cultivation. A series of soil erosion field experiments were conducted from 2022 to 2023 using natural rainfall to investigate the influence of selected intercrop mixtures during the growing season on sediment yields and surface runoff volume. The results revealed a gradual decrease in surface runoff volume and sediment yields over the growing season. Significantly reduced surface runoff volume and soil loss were observed in two tested intercropped plots S2 - rye (Secale cereale) and incarnate clover (Trifolium incarnatum); S3 - ryegrass only (Lolium)), compared to a control plot managed conventionally with maize (S1). Surface runoff volume and soil loss from S2 and S3 reached 2.57-43.5% and 1.26-11.65% of the control plot, respectively. These findings highlight the soil conservation effect of intercrop technologies (S2 and S3) in mitigating soil erosion in maize cultivation. The importance of vegetation cover in reducing soil erosion intensified over time. Intercropping holds promise as a sustainable agricultural management strategy for sloping maize fields. [ABSTRACT FROM AUTHOR]

Agricultural landscape management and climate seasonality can influence soil structure, hydraulic conductivity, and air permeability within the context of soil water and soil gas mobility. To investigate this, in situ and laboratory-based data were collected from three agricultural landscape positions within a watershed in eastern Ontario, Canada during a growing season. Macropore classification, water infiltration tests, and air permeability measurements were conducted in situ and standard soil characterizations were carried out on soil samples. Hydraulic conductivity of the soil matrix, based on grain size data, indicated that the highest values were consistently measured in the B horizon at each landscape setting. Macropores were found to be more abundant within uncultivated drainage ditch bank soils, compared to the adjacent cropped fields. Macropores in the ditch bank soils were exclusively consisted of circular biopores, while both circular and linear macropores were observed in the cultivated field soils. Air permeability, vertical hydraulic conductivity, and horizontal hydraulic conductivity were also greater in the uncultivated soils, relative to the cultivated soils. Field saturated hydraulic conductivity measurements offered evidence of anisotropy, likely due to the vertical nature of the macropore features. Macropore disposition and extent varied over the growing season, especially in the cultivated field soils where tillage and field trafficking are physically disruptive. Seasonality of macropore development will influence temporal changes in advection-based mass exchange of gas and water in the vadose zone. Modeling of mass exchange in agricultural soils should consider time variability in macroporosity to more realistically characterize infiltration and soil gas emissions. [ABSTRACT FROM AUTHOR]

Copyright of Acta Biológica Colombiana is the property of Universidad Nacional de Colombia, Facultad de Biologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To describe the characteristics of the number of hectares (located in the UMAs registered in the state of Chihuahua) used for the white-tailed deer free-range production, the level of exploitation of the species, and its economic value. Design/Methodology/Approach: This study determined the number of Units for the Conservation, Management, and Sustainable Use of Wildlife (UMAs) registered in the state of Chihuahua, where white tailed deer had been exploited since 2015. Forty-three municipalities in the state of Chihuahua, with a total of 159 UMAs, were analyzed. Twenty-three randomly selected UMAs were characterized, taking into account the hectares and the presence of white-tailed deer per municipality. Finally, the exploitation value of the species use per community was established in order to determine its exploitation and economic value. Results: The total area used for the exploitation of the white-tailed deer reaches 1,067,380 hectares. Thirtytwo municipalities had potential for the exploitation of white-tailed deer. Thirty-three deer were hunted per season in the 23 UMAs under study, which accounts for a $990,000 Mexican pesos gross income for the state of Chihuahua per season; this exploitation generates a total of 115 temporary jobs for the communities surrounding the 23 UMAs studied. Chihuahua's UMAs welcome a total of 33 white-tailed deer hunters per season. Hunters pay $30,000 to $34,000 Mexican pesos for each white-tailed deer specimen. Study Limitations/Implications: The study provides an overview of the current state of the UMAs in the state of Chihuahua that have a permit for the white-tailed deer hunting exploitation. Each of the UMAs under study has specific characteristics, including: the services offered, the associated hunting species, and the exploitation populations under an integrated sustainability arrangement. This study does not include the benefits of exploiting associated species, such as the collared peccary (Dicotyles tajacu) and the wild turkey (Meleagris gallopavo). Findings/Conclusions: Based on the number of registered UMAs, 32 out of 40 municipalities use 100% of their registered area for the exploitation of white-tailed deer. The white-tailed deer hunting exploitation increases the profitability and productivity of livestock ranches. [ABSTRACT FROM AUTHOR]

The Gynoxyoid clade of the Senecioneae (Asteraceae) until now included the five genera Aequatorium, Gynoxys, Nordenstamia, Paracalia and Paragynoxys as diagnosed using selected morphological characters. In their pre-phylogenetic circumscription, the genera Aequatorium and Paragynoxys were considered to inhabit the northern Andes in contrast to Nordenstamia and Paracalia that occur in the central Andes. The most species-rich genus, Gynoxys, was believed to be distributed throughout the Andes. We use a recently established plastid phylogenomic framework that rendered Gynoxys paraphyletic to further evaluate the delimitation of genera in the Gynoxyoid clade. We examine the morphological variation of all members of the Gynoxyoid to identify characters potentially informative at genus level. This results in a matrix of eleven, mostly multistate characters, including those originally used to diagnose these genera. The ancestral character state inference displays a high level of homoplasy, but nevertheless supports the recognition of four genera. Aequatorium is characterised by white radiate capitula. Paracalia and Paragynoxys share white flowers and floral characteristics, such as flower opening and length of disc flowers lobes, as plesiomorphic states, but differ in habit (scandent shrubs vs. trees). Paracalia also retained white flowers, but its two species are characterised by the absence of outer phyllaries. The genera Gynoxys and Nordenstamia comprise species with yellow capitula which appear to be a derived feature in the Gynoxyoids. The genus Nordenstamia, with eight species, is synonymised under Gynoxys since molecular evidence shows its species nested within various parts of the Gynoxys subclade and the morphological variation of Nordenstamia falls well within that of Gynoxys. With the goal to assign all species to four genera (Aequatorium, Gynoxys, Paracalia and Paragynoxys), we assess the states for the eleven characters for all members of the Gynoxyoids and generate new ETS and ITS sequences for 171 specimens belonging to 49 species to further support their generic placement. We provide a taxonomic treatment for the four genera recognised here including amended diagnoses and morphological descriptions. Furthermore, a species-level taxonomic backbone is elaborated for all genera using electronic tools that list 158 currently accepted names and synonyms (209 names in total) with the respective protologue and type information, as well as notes on the current understanding of species limits. Eleven names are newly synonymised, two are lectotypified and eight are newly transferred to other genera. [ABSTRACT FROM AUTHOR]

The return to equivalent capability was evaluated on a >1000 km oil and gas pipeline corridor on the western Canadian prairies. Resource constraints limited this first phase of sampling to soils more likely damaged by disturbance. Three pipelines were selected to span a 55‐year period of construction. Data were collected from four transects established within each of six randomly chosen quarter sections (each 65 hectares) that included reference sites. Laboratory analysis provided data for organic carbon, pH, calcium carbonate equivalent, sodicity, salinity, and particle size distribution. Field procedures were used to obtain data for topsoil thickness, bulk density, aggregate size distribution, and carbonate distribution. The Canadian Land Suitability Rating System was employed to evaluate and compare the land capability (LSRS rating) of three pipelines to that of adjacent reference capability. Pipeline‐reference differences were detected in the topsoil for soil organic carbon (83% of reference), calcium carbonate equivalent (62% higher), and pH (0.4 units higher), and in the subsoil for bulk density (2% higher) and electrical conductivity (a fivefold increase). Carbonates were observed more frequently on the pipelines than on references. Soil organic carbon increased and electrical conductivity decreased with time since construction. The mode of land capability was class 4 on the corridor and class 3 on references. Residual effects remained. Neither soil conservation and reclamation practices, nor natural recovery had yet achieved equivalent capability for the target soil group, representing 17% of the extent of the corridor. [ABSTRACT FROM AUTHOR]

Temperate grasslands are called the breadbaskets of the world. Due to most continental climate conditions, humus-rich soils have been developed. These soils are very well suited for grain production. This is why extensive conversions from natural steppe to arable land have been implemented in this biome. The Kulunda Steppe, in Southwest Siberia and Central Asia, occupies large parts of the driest regions of the Eurasian Steppe Belt. It was one of the sites of the Virgin Land Campaign realized in the former Soviet Union in the 1950s and 1960s. Intensive agricultural practices have caused significant soil degradation, mainly through humus loss and soil erosion. This results in the degradation of organic carbon, altering the physical and chemical structure of the chestnut soils and impacting their water storage capacity. Against the background of climatic changes, a further intensification of these processes and conditions is to be expected. To stabilize soil carbon and optimize moisture utilization, it is necessary to extensively introduce worldwide experiences in conservation cropping technologies (such as no-till, min-till, and direct seeding) in the area. This study aimed to determine the effects of different cropping systems on soil water storage and water availability. The study’s initial hypothesis was that the soil conservational cropping system has advantages against the traditional deep tillage (24 cm). This hypothesis was based on extensive global experience studying the effects of different agricultural management systems on soil-water balance. In 2013–2016, an experiment was conducted for the first time in the Kulunda steppe to instrumentally measure soil moisture and matrix potential at 30–60–120 cm depth under traditional and conservation technology using innovative meteorological and soil hydrological stations. Statistically significant advantages of no-till over deep tillage (24 cm) in terms of moisture retention were found, confirming the hypothesis of this study. Besides, this groundbreaking study reveals new possibilities for soil monitoring in the region. The acquired data are applicable for predictive models using remote sensing. Moreover, the results on the management effects for the soil water balance provide basic approaches to soil water monitoring, offering important data for evaluating model results and remote sensing products for the region. [ABSTRACT FROM AUTHOR]

Saturated and near-saturated soil hydraulic conductivities Kh (mmh-1) determine the partitioning of precipitation into surface runoff and infiltration and are fundamental to soils' susceptibility to preferential flow. Recent studies found indications that climate factors influence Kh , which is highly relevant in the face of climate change. In this study, we investigated relationships between pedoclimatic factors and Kh and also evaluated effects of land use and soil management. To this end, we collated the Open Tension-disk Infiltrometer Meta-database (OTIM), which contains 1297 individual data entries from 172 different publication sources. We analysed a spectrum of saturated and near-saturated hydraulic conductivities at matric potentials between 0 and 100 mm. We found that methodological details like the direction of the wetting sequence or the choice of method for calculating infiltration rates to hydraulic conductivities had a large impact on the results. We therefore restricted ourselves to a subset of 466 of the 1297 data entries with similar methodological approaches. Correlations between Ks and Kh at higher supply tensions decreased especially close to saturation, indicating a different flow mechanism at and very close to saturation than towards the dry end of the investigated tension range. Climate factors were better correlated with topsoil near-saturated hydraulic conductivities at supply tensions ≥ 30 mm than soil texture, bulk density and organic carbon content. We find it most likely that the climate variables are proxies for soil macropore networks created by the respective biological activity, pedogenesis and climate-specific land use and management choices. Due to incomplete documentation in the source publications of OTIM, we were able to investigate only a few land use types and agricultural management practices. Land use, tillage system and soil compaction significantly influenced Kh , with effect sizes appearing comparable to the ones of soil texture and soil organic carbon. The data in OTIM show that experimental bias is present, introduced by the choice of measurement time relative to soil tillage, experimental design or data evaluation procedures. The establishment of best-practice rules for tension-disk infiltrometer measurements would therefore be helpful. Future studies are needed to investigate how climate shapes soil macropore networks and how land use and management can be adapted to improve soil hydraulic properties. Both tasks require large numbers of new measurement data with improved documentation on soil biology and land use and management history. [ABSTRACT FROM AUTHOR]

Most of the existing research on enterprise tax arrears prediction is based on the financial situation of enterprises. The influence of various relationships among enterprises on tax arrears is not considered. This paper integrates multivariate data to construct an enterprise knowledge graph. Then, the correlations between different enterprises and risk events are selected as the prediction variables from the knowledge graph. Finally, a tax arrears prediction machine learning model is constructed and implemented with better prediction power than earlier studies. The results show that the correlations between enterprises and tax arrears events through the same telephone number, the same E-mail address and the same legal person commonly exist. Based on these correlations, potential tax arrears can be effectively predicted by the machine learning model. A new method of tax arrears prediction is established, which provides new ideas and analysis frameworks for tax management practice. [ABSTRACT FROM AUTHOR]

This paper shows the changes in water sorptivity (Sw) and hydrophobicity following soil contamination with petroleum hydrocarbons (PHs) under different soil moistures. Laboratory experiments were carried out to verify that contamination with PHs reduces Sw, thus affecting the infiltrability, which in practice influences the field water capacity and the availability of water for plants. Soil water repellency (SWR) was estimated by the repellency index (R) and water drop penetration time (WDPT). The increase in PHs contamination contributed to SWR and caused a significant decrease in Sw. With the decrease in moisture, the water sorptivity of the soil increased, reaching its maximum at 0.12–0.15 cm3 cm−3, which was the threshold value in the case of the analysed soil, and then decreased drastically. The R index and the WDPT revealed a similar trend, inversely related to the level of soil contamination with PHs. The increase in SWR and the accompanying decrease in Sw made the soil less resistant to drought. The total amount of water available to plants in the control soil was 19.04%, whereas contamination with PHs equal to 100 g kg−1 caused a decrease to 6.36%. The almost threefold decrease in the total amount of water has a fundamental influence on increasing the risk of soil drought. The results obtained indicated that the interrelationship presented between the level of contamination with PHs, water sorptivity, SWR and soil moisture are the keys to predicting the environmental effects of contamination with PHs. The obtained results indicate that the undertaken remediation measures aimed at restoring the hydrological function of the soil system should be preceded by an assessment of soil hydrophobicity. [ABSTRACT FROM AUTHOR]

Background: Soil compaction can occur due to the intensity of tractor traffic in the tillage process. The objective of this study was to determine the changes in physical, mechanical properties of the soil and plant growth that occurred due to tractor traffic and how it would affect if the addition of organic matter (compost) was added to the soil. Methods: The experimental work was conducted at the Sugarcane Plantation of PTPN II Klumpang at an initial soil moisture content of 24.69% and a bulk density of 1.08 gr/cm3 with compost and no compost then the land is traversed by the tractor with 2,4 and 6 passes. Result: The results of indicate that the tractor trajectory and the addition of compost have a significant effect on soil compaction. The highest values for water content, bulk density, particle density and penetration resistance were obtained at 6 times tractor traffic with soil without compost sowing respectively 35.36%, 1.31 gr/cm3, 1.87 gr/cm3, 9.61 kgf/cm2, while in soil with compost, the values obtained were 33.62%, 1.23 gr/cm3, 1.82 gr/cm3, 9.04 kgf/cm2, respectively. These findings indicated that the application of compost can reduce the level of soil density so that plant growth becomes better and more even rate of plant growth is obtained than without compost. [ABSTRACT FROM AUTHOR]

Physically based distributed hydrological models aim at an adequate representation of hydrological processes, including runoff generation. A significant proportion of runoff is generated through the subsurface, that is, by groundwater flow or unsaturated subsurface stormflow. However, in the case of high rainfall intensity and/or low soil‐surface infiltrability, surface runoff may strongly contribute to total runoff, too, either through saturation excess ("Dunne‐type surface runoff") or infiltration excess ("Hortonian surface runoff"). Both types of surface runoff can be rather important if antecedent wetness is high and parts of the catchment area are saturated (leading to saturation excess), or if the maximum infiltration rate into the soil surface is less than the actual rainfall intensity (resulting in infiltration excess). Even though the latter process can be very important during high‐intensity rainstorms, both for flood generation and for matter transport linked with surface runoff, an appropriate consideration of this process in catchment models is still challenging. Actually, budgeting between the actual rainfall intensity and the soil surface infiltration capacity is required and there are a number of challenges in the details: First, the "real" rainfall intensity may vary tremendously in time increments much smaller than the time step of the model. The soil surface infiltrability can also be significantly reduced, for example, by crusting, compaction or sealing of the soil surface or through hydrophobic effects. Otherwise, soil infiltrability can be strongly enhanced as a consequence of preferential flow paths/macropores caused by, for example, bioturbations or other voids. Finally, there is a high variability of such soil surface features at a small spatial scale, below the typical spatial modelling unit. We present observational data and approaches to deal with these challenges. We show results from combined infiltration/infiltration‐excess experiments and observations at three spatial scales. Then, we present a model approach based on a double‐porosity soil enabling the combined modelling of high infiltration rates and dampened soil moisture distribution after termination of infiltration, as observable in the field. Furthermore, we present an approach to model the effects of soil surface conditions on actual infiltration capacity. These approaches improved the plausibility and explanatory power of the model concerning surface runoff generation and soil moisture dynamics. For instance, model results at the plot and hillslope scales show that it is possible to simulate high infiltration rates jointly with a relatively slow movement of moisture within the soil matrix, field phenomena often observed in the case of heavy rainfall. We also simulate non‐linear and space–time variability effects of soil surface conditions, which can be important for flood generation. [ABSTRACT FROM AUTHOR]

The objective of crime prediction, one of the most important technologies in social computing, is to extract useful information from many existing criminal records to predict the next process-related crime. It can aid the police in obtaining criminal information and warn the public to be vigilant in certain areas. With the rapid growth of big data, the Internet of Things, and other technologies, as well as the increasing use of artificial intelligence in forecasting models, crime prediction models based on deep learning techniques are accelerating. Therefore, it is necessary to classify the existing crime prediction algorithms and compare in depth the attributes and conditions that play an essential role in the analysis of crime prediction algorithms. Existing crime prediction methods can be roughly divided into two categories: those based on conventional machine learning and those based on contemporary deep learning. This survey analyses the fundamental theories and procedures. The most frequently used data sets are then enumerated, and the fundamental procedures of various algorithms are also analyzed in this paper. In light of the insufficient scale of existing data in this field, the ambiguity of data types used to predict crimes, and the absence of public data sets that have a significant impact on the research of algorithm models, this survey proposes the construction of a machine learning-based big data research model to address these issues. Future researchers who will enter this field are provided with a guide to the direction of future research development. [ABSTRACT FROM AUTHOR]

Copyright of Revista FAVE is the property of Universidad Nacional del Litoral and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Individuals with traumatic brain injury (TBI) in Latin America experience high levels of disability and extremely poor functional outcomes, and their informal caregivers play a key role in their rehabilitation and care. OBJECTIVE: To improve TBI rehabilitation through stronger informal caregiving, this study developed and evaluated an evidence-based and culturally appropriate Transition Assistance Program (TAP) for informal caregivers of individuals with TBI in Latin America, specifically targeting the time period before and after the transition from hospital to home. METHODS: A sample of 89 people with a new TBI and their primary informal caregiver (n = 178) was recruited from two hospitals in Mexico City, Mexico, and in Cali, Colombia. Caregivers were randomly assigned to either the TAP group or to a control group receiving the standard care provided by the hospital. Caregivers completed measures of depression and burden, and individuals with TBI completed measures of depression and self-perceived burden on caregivers before hospital discharge and at 2- and 4-month follow ups. RESULTS: Caregivers in the TAP group reported significantly lower burden than those in the control group and marginally lower depression. Individuals with TBI whose caregivers had been in the TAP group reported significantly lower depression than those whose caregivers had been in the control group, and a non-significant but lower self-perceived burden on their caregivers. CONCLUSION: The results suggest that the TAP has strong potential to benefit both TBI caregivers and individuals with TBI during the transition from acute TBI hospitalization to home in Latin America, generally showing small-or medium-sized effects on key outcomes. [ABSTRACT FROM AUTHOR]

Decreasing physical quality of Mollisols in the Argentinean Pampas region is observed due to simplified crop rotations. The main objective of this work was to evaluate the effects of cover cropping management on soil water capture, transport, and storage as compared with different crop rotations with bare fallow in two different and representative Mollisols of the Argentinean Pampas region (one Typic Argiudoll [TA] and one Typic Hapludoll [TH]). Water capture, transport, and storage processes were assessed through soil sorptivity, infiltration tests at different pressures heads, and soil water retention curve determination. In addition, aggregate stability and soil organic carbon (SOC) were determined and the relationship between studied variables and processes was evaluated. It was observed that soybean [Glycine max (L.) Merr.] monocultures jeopardize Mollisols conservation, decreasing water capture and transport and SOC content. The inclusion of cover cropping management increased the soil water transport in the TA and water capture in the TH, as compared with bare fallow rotations. In this sense, our results show that cover cropping could be a suitable management in order to recover degraded soils due to simplified crop rotations in Mollisols from the Argentina Pampas region. Core Ideas: Effects of cover crops on soil hydraulic properties depended on the soil type.Soybean monocultures decreased water capture and transport.Cover crops increased water transport in the Typic Argiudoll.Cover crops increased water capture in the Typic Hapludoll. [ABSTRACT FROM AUTHOR]

Parathyroid hormone-related protein (PTHrP) C-terminal peptides regulate the metabolism of bone cells. PHTrP [107–111] (osteostatin) promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis. In addition to its positive effects on osteoblasts, osteostatin may inhibit bone resorption. The aim of this study was to determine the effects of osteostatin on human osteoclast differentiation and function. We used macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor κB ligand (RANKL) to induce the osteoclast differentiation of adherent human peripheral blood mononuclear cells. Tartrate-resistant acid phosphatase (TRAP) staining was performed for the detection of the osteoclasts. The function of mature osteoclasts was assessed with a pit resorption assay. Gene expression was evaluated with qRT-PCR, and nuclear factor of activated T cells, cytoplasmic 1 (NFATc1) nuclear translocation was studied by immunofluorescence. We observed that osteostatin (100, 250 and 500 nM) decreased the differentiation of osteoclasts in a concentration-dependent manner, but it did not modify the resorptive ability of mature osteoclasts. In addition, osteostatin decreased the mRNA levels of cathepsin K, osteoclast associated Ig-like receptor (OSCAR) and NFATc1. The nuclear translocation of the master transcription factor in osteoclast differentiation NFATc1 was reduced by osteostatin. Our results suggest that the anti-resorptive effects of osteostatin may be dependent on the inhibition of osteoclastogenesis. This study has shown that osteostatin controls human osteoclast differentiation in vitro through the downregulation of NFATc1. [ABSTRACT FROM AUTHOR]

This study evaluated stakeholders' perspectives regarding participation in two hypothetical neuromodulation trials focused on individuals with Alzheimer's disease and related disorders (ADRDs). Stakeholders (i.e., individuals at risk for ADRDs [ n = 56], individuals with experience as a caregiver for someone with a cognitive disorder [ n = 60], and comparison respondents [ n = 124]) were recruited via MTurk. Primary outcomes were willingness to enroll (or enroll one's loved one), feeling lucky to have the opportunity to enroll, and feeling obligated to enroll in two protocols (transcranial magnetic stimulation, TMS; deep brain stimulation, DBS). Relative to the Comparison group, the At Risk group endorsed higher levels of "feeling lucky" regarding both research protocols, and higher willingness to participate in the TMS protocol. These findings provide tentative reassurance regarding the nature of decision making regarding neurotechnology-based research on ADRDs. Further work is needed to evaluate the full range of potential influences on research participation. [ABSTRACT FROM AUTHOR]

In furrow irrigation, the maximum lateral movement of water in ridges is more desirable than the vertical downward movement. This can be achieved by compacting the furrows. Thus, the study examines the impact on furrow soil compaction by tractor wheel trafficking during mechanical operations in the different soil types. In this experiment, the three-wheel tractor compaction includes: 1) control (no soil compaction), 2) compaction through 3-wheel tractor passes, and 3) compaction through 6-wheel passes under three different soil textural classes such as: clay loam, silty clay loam and silty loam soils. The impact of various treatments on clay loam, silty clay loam, and silty loam under 3- and 6-wheel passes showed increased bulk density (7-12%), field capacity (9-19%), ridge storage efficiency (35-38%), water use efficiency (16-20.5%) and decreased soil porosity (7-16%), infiltration (8-20%), and furrow storage efficiency (28-41%) over the control. This study shows comparable results of 6-passes with other studies in which more than 6-passes were used to compact the soil. This study suggested that farmers can maximise water use efficiency by compacting their furrows using 6-passes tractor trafficking. [ABSTRACT FROM AUTHOR]

Parkinson's disease (PD) is one of the most common neurodegenerative diseases. It is characterized pathologically by the aggregation of α-synuclein (αS) in the form of Lewy bodies and Lewy neurites. A major challenge in PD therapy is poor efficiency of drug delivery to the brain due to the blood–brain barrier (BBB). For this reason, nanomaterials, with significant advantages in drug delivery, have gained attention. On the other hand, recent studies have shown that nanoparticles can promote αS aggregation in salt solution. Therefore, we tested if nanoparticles could have the same effect in cell models. We found that nanoparticle can induce cells to form αS inclusions as shown in immunocytochemistry, and detergent-resistant αS aggregates as shown in biochemical analysis; and nanoparticles of smaller size can induce more αS inclusions. Moreover, the induction of αS inclusions is in part dependent on endolysosomal impairment and the affinity of αS to nanoparticles. More importantly, we found that the abnormally high level of endogenous lysosomotropic biomolecules (e.g., sphingosine), due to impairing the integrity of endolysosomes could be a determinant factor for the susceptibility of cells to nanoparticle-induced αS aggregation; and deletion of GBA1 gene to increase the level of intracellular sphingosine can render cultured cells more susceptible to the formation of αS inclusions in response to nanoparticle treatment. Ultrastructural examination of nanoparticle-treated cells revealed that the induced inclusions contained αS-immunopositive membranous structures, which were also observed in inclusions seeded by αS fibrils. These results suggest caution in the use of nanoparticles in PD therapy. Moreover, this study further supports the role of endolysosomal impairment in PD pathogenesis and suggests a possible mechanism underlying the formation of membrane-associated αS pathology. [ABSTRACT FROM AUTHOR]

The saturated soil hydraulic conductivity (Ksat) is a key parameter in many hydrological and climate models. Ksat values are primarily determined from basic soil properties and may vary over several orders of magnitude. Despite the availability of Ksat datasets in the literature, significant efforts are required to combine the data before they can be used for specific applications. In this work, a total of 13 258 Ksat measurements from 1908 sites were assembled from the published literature and other sources, standardized (i.e., units made identical), and quality checked in order to obtain a global database of soil saturated hydraulic conductivity (SoilKsatDB). The SoilKsatDB covers most regions across the globe, with the highest number of Ksat measurements from North America, followed by Europe, Asia, South America, Africa, and Australia. In addition to Ksat , other soil variables such as soil texture (11 584 measurements), bulk density (11 262 measurements), soil organic carbon (9787 measurements), moisture content at field capacity (7382), and wilting point (7411) are also included in the dataset. To show an application of SoilKsatDB, we derived Ksat pedotransfer functions (PTFs) for temperate regions and laboratory-based soil properties (sand and clay content, bulk density). Accurate models can be fitted using a random forest machine learning algorithm (best concordance correlation coefficient (CCC) equal to 0.74 and 0.72 for temperate area and laboratory measurements, respectively). However, when these Ksat PTFs are applied to soil samples obtained from tropical climates and field measurements, respectively, the model performance is significantly lower (CCC = 0.49 for tropical and CCC = 0.10 for field measurements). These results indicate that there are significant differences between Ksat data collected in temperate and tropical regions and Ksat measured in the laboratory or field. The SoilKsatDB dataset is available at 10.5281/zenodo.3752721 and the code used to extract the data from the literature and the applied random forest machine learning approach are publicly available under an open data license. [ABSTRACT FROM AUTHOR]

Objective: To review information related with the reproductive physiology and management of white-tailed deer for reproductive specialists and producers. Design/methodology/approach: The information presented in this document relies on the review of scientific papers and on experience gained in white-tail deer production systems. Results: White-tailed deer is a species with seasonal reproduction and one of the most important hunting species in Mexico. Currently, all reproductive biotechnologies applied to small ruminants can be used in whitetailed deer. Limitations of the study/implications: Information regard the physiology and reproductive management of white-tailed deer is limited, probably due to conditions specific to its production system. Findings/conclusions: Research and publication of information regard the physiology and reproductive management of white-tailed deer is needed. [ABSTRACT FROM AUTHOR]

Several useful animal models for parkinsonism have been developed so far. Haloperidol‐induced catalepsy is often used as a rodent model for the study of motor impairments observed in Parkinson's disease and related disorders and for the screening of potential antiparkinsonian compounds. The objective of this systematic review is to identify publications that used the haloperidol‐induced catalepsy model for parkinsonism and to explore the methodological characteristics and the main questions addressed in these studies. A careful systematic search of the literature was carried out by accessing articles in three different databases: Web of Science, PubMed and SCOPUS. The selection and inclusion of studies were performed based on the abstract and, subsequently, on full‐text analysis. Data extraction included the objective of the study, study design and outcome of interest. Two hundred and fifty‐five articles were included in the review. Publication years ranged from 1981 to 2020. Most studies used the model to explore the effects of potential treatments for parkinsonism. Although the methodological characteristics used are quite varied, most studies used Wistar rats as experimental subjects. The most frequent dose of haloperidol used was 1.0 mg/kg, and the horizontal bar test was the most used to assess catalepsy. The data presented here provide a framework for an evidence‐based approach to the design of preclinical research on parkinsonism using the haloperidol‐induced catalepsy model. This model has been used routinely and successfully and is likely to continue to play a critical role in the ongoing search for the next generation of therapeutic interventions for parkinsonism. [ABSTRACT FROM AUTHOR]

Suicidal behavior is a leading cause of death and often commences during adolescence/young adulthood (15~29 years old). The hippocampus, which consists of multiple functionally specialized subfields, may contribute to the pathophysiology of depression and suicidal behavior. We aimed to investigate the differences of hippocampal subfield volume between major depressive disorder (MDD) patients with and without suicide attempts and healthy controls in adolescents and young adults. A total of 40 MDD suicide attempters (MDD+SA), 27 MDD patients without suicide attempt (MDD-SA), and 37 healthy controls (HC) were recruited. High-resolution T1 MRI images were analyzed with the automated hippocampal substructure module in FreeSurfer 6.0. Volume differences among the groups were analyzed by a generalized linear model controlling for intracranial cavity volume (ICV). The relationship between hippocampal subfield volumes and clinical characteristics (HAM-D and SSI scores) was assessed using two-tailed partial correlation controlling for ICV in MDD+SA and MDD-SA. We found that MDD-SA had significantly smaller bilateral hippocampal fissure volume than HC and MDD+SA. No significant correlation was observed between hippocampal subfield volume and clinical characteristics (HAM-D and SSI scores) in MDD+SA and MDD-SA. Adolescent/young adult suicide attempters with MDD suicide attempters have larger bilateral hippocampal fissures than depressed patients without suicide attempts, independently from clinical characteristics. Within the heterogeneous syndrome of major depressive disorder that holds a risk for suicidality for subgroups, hippocampal morphology may help to explain or possibly predict such risk, yet longitudinal and functional studies are needed for understanding the biological mechanisms underlying. [ABSTRACT FROM AUTHOR]

This article examines the relationship between soil heterogeneity and cellulolytic activity. The investigated substrate was a typical chernozem (black soil). Cellulolytic activity was studied by the application method across a regular grid of 7×15 points (21×45 m). The distance between the measurement points was 3 m. Soil heterogeneity determined by the measurement of soil penetration resistance using a hand penetrometer Eijkelkamp. Measurements of soil penetration resistance were fixed to a depth of 100 cm at intervals of 5 cm. Geostatistical analysis showed a high level of spatial dependence of soil cellulolytic activity. Significant correlations were obtained between the spatial distribution of cellulolytic activity and soil penetration resistance at different depths. The results reflect a significant correlation of soil conditions at different depths. [ABSTRACT FROM AUTHOR]

Parkinson's disease (PD) is characterized by non-motor symptoms as well as motor deficits. The non-motor symptoms rarely appear individually and occur simultaneously with motor deficits or independently. However, a comprehensive research on the non-motor symptoms using an experimental model of PD remains poorly understood. The aim of the current study is to establish a chronic mouse model of PD mimicking the comprehensive non-motor symptoms of human PD by injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and probenecid (MPTP/p). The non-motor and motor symptoms were evaluated by performing buried food, short-term olfactory memory, hot plate, open field, tail suspension, Y maze, novel object recognition, bead expulsion, one-h stool collection, rotarod, rearing, catalepsy, and akinesia tests after 10 injections of MPTP/p into mice. The expression levels of α-synuclein, glial fibrillary acidic protein (GFAP), tyrosine hydroxylase (TH) or DJ-1 were analyzed by Western blotting or immunostaining. MPTP/p-treated mice achieved to reproduce the key features of non-motor symptoms including olfactory deficit, thermal hyperalgesia, anxiety, depression, cognitive decline, and gastrointestinal dysfunction in addition to motor deficits. The MPTP/p-treated mice also showed the high levels of α-synuclein and low levels of TH and DJ-1 in striatum, substantia nigra, olfactory bulb, hippocampus, amygdala, prefrontal cortex, locus coeruleus, or colon. In addition, the expression levels of phosphorylated-α-synuclein and GFAP were elevated in the striatum and substantia nigra in the MPTP/p-treated mice. Taken together, our study clarifies that the chronic MPTP/p-treated mice have a variety of non-motor dysfunctions as well as motor abnormalities by α-synuclein overexpression and dopaminergic depletion. Therefore, the study of comprehensive phenotypes of non-motor symptoms in one PD model would advance in-depth understandings of neuropathological alternations and contribute to future strategies for PD treatment. [ABSTRACT FROM AUTHOR]

Parkinson's disease (PD) is the second most common neurodegenerative disease in the elder population, pathologically characterized by the progressive loss of dopaminergic neurons in the substantia nigra. While the precise mechanisms underlying the pathogenesis of PD remain unknown, various genetic factors have been proved to be associated with PD. To date, at least 23 loci and 19 disease-causing genes for PD have been identified. Although monogenic (often familial) cases account for less than 5% of all PD patients, exploring the phenotypes of monogenic PD can help us understand the disease pathogenesis and progression. Primary motor symptoms are important for PD diagnosis but only detectable at a relatively late stage. Despite typical motor symptoms, various non-motor symptoms (NMS) including sensory complaints, mental disorders, autonomic dysfunction, and sleep disturbances also have negative impacts on the quality of life in PD patients and pose major challenges for disease management. NMS is common in all stages of the PD course. NMS can occur long before the onset of PD motor symptoms or can present in the middle or late stage of the disease accompanied by motor symptoms. Therefore, the profiling and characterization of NMS in monogenic PD may help the diagnosis and differential diagnosis of PD, which thereby can execute early intervention to delay the disease progression. In this review, we summarize the characteristics, clinical phenotypes, especially the NMS of monogenic PD patients carrying mutations of SNCA, LRRK2, VPS35, Parkin, PINK1, DJ-1 , and GBA. The clinical implications of this linkage between NMS and PD-related genes are also discussed. [ABSTRACT FROM AUTHOR]

Parkinson's disease (PD) is one of the most common movement disorders with loss of dopaminergic neurons and the presence of Lewy bodies in certain brain areas. However, it is not clear how Lewy body (inclusion with protein aggregation) formation occurs. Mutations in leucine‐rich repeat kinase 2 (LRRK2) can cause a genetic form of PD and contribute to sporadic PD with the typical Lewy body pathology. Here, we used our recently identified LRRK2 GTP‐binding inhibitors as pharmacological probes to study the LRRK2‐linked ubiquitination and protein aggregation. Pharmacological inhibition of GTP‐binding by GTP‐binding inhibitors (68 and Fx2149) increased LRRK2‐linked ubiquitination predominantly via K27 linkage. Compound 68‐ or Fx2149 increased G2019S‐LRRK2‐linked ubiquitinated aggregates, which occurred through the atypical linkage types K27 and K63. Coexpression of K27R and K63R, which prevented ubiquitination via K27 and K63 linkages, reversed the effects of 68 and Fx2149. Moreover, 68 and Fx2149 also promoted G2019S‐LRRK2‐linked aggresome (Lewy body‐like inclusion) formation via K27 and K63 linkages. These findings demonstrate that LRRK2 GTP‐binding activity is critical in LRRK2‐linked ubiquitination and aggregation formation. These studies provide novel insight into the LRRK2‐linked Lewy body‐like inclusion formation underlying PD pathogenesis. [ABSTRACT FROM AUTHOR]

Copyright of Revista Mexicana de Ciencias Agrícolas is the property of Instituto Nacional de Investigaciones Forestales, Agricolas y Pecuarias and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Latin America has exceptionally high rates of traumatic brain injury (TBI), but very little research has been conducted on longitudinal TBI outcomes in this global region. OBJECTIVE: This study examined whether cognitive dysfunction and social disadaptation in individuals with TBI in Latin America at hospital discharge predict longitudinal trajectories of depression at baseline, 2 months, and 4 months. METHODS: A sample of 109 people with a new TBI was recruited from three hospitals: Mexico City, Mexico, Cali, Colombia and Neiva, Colombia. Participants completed measures of cognitive dysfunction and social disadaptation before hospital discharge and measures of depression at baseline, 2 months, and 4 months. RESULTS: Results suggested that depression scores were found to decrease over time in a quadratic (or U-shaped) fashion, and more significant cognitive dysfunction at hospital discharge was associated with higher longitudinal depression trajectories. Social disadaptation did not exert a unique effect on depression trajectories after controlling for cognitive dysfunction. Depression trajectories changed differentially over time as a function of baseline cognitive dysfunction, such that for those with high cognitive impairment, depression scores started high and then dropped to a moderated range and plateaued, but for individuals with low cognitive dysfunction, depression scores started lower and decreased linearly but moderately. CONCLUSIONS: The results suggest a strong need for neuropsychological assessments and evidence-based cognitive rehabilitation strategies to be implemented immediately after TBI in Latin America, which could exert salubrious effects on depression trajectories over time. [ABSTRACT FROM AUTHOR]

Regulated cell death (RCD) plays a fundamental role in human health and disease. Apoptosis is the best-studied mode of RCD, but the importance of other modes has recently been gaining attention. We have previously demonstrated that adult rat hippocampal neural stem (HCN) cells undergo autophagy-dependent cell death (ADCD) following insulin withdrawal. Here, we show that Parkin mediates mitophagy and ADCD in insulin-deprived HCN cells. Insulin withdrawal increased the amount of depolarized mitochondria and their colocalization with autophagosomes. Insulin withdrawal also upregulated both mRNA and protein levels of Parkin, gene knockout of which prevented mitophagy and ADCD. c-Jun is a transcriptional repressor of Parkin and is degraded by the proteasome following insulin withdrawal. In insulin-deprived HCN cells, Parkin is required for Ca2+ accumulation and depolarization of mitochondria at the early stages of mitophagy as well as for recognition and removal of depolarized mitochondria at later stages. In contrast to the pro-death role of Parkin during mitophagy, Parkin deletion rendered HCN cells susceptible to apoptosis, revealing distinct roles of Parkin depending on different modes of RCD. Taken together, these results indicate that Parkin is required for the induction of ADCD accompanying mitochondrial dysfunction in HCN cells following insulin withdrawal. Since impaired insulin signaling is implicated in hippocampal deficits in various neurodegenerative diseases and psychological disorders, these findings may help to understand the mechanisms underlying death of neural stem cells and develop novel therapeutic strategies aiming to improve neurogenesis and survival of neural stem cells. [ABSTRACT FROM AUTHOR]

Copyright of Colloquium Agrariae is the property of Asociacao Prudentina de Educacao e Cultura (APEC) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Parkinson’s disease (PD) is a neurodegenerative disorder of unknown etiology. The main treatment of PD consists of medication with dopamine-based drugs, which palliate the symptoms but may produce adverse effects after chronic administration. Accordingly, there is a need to develop novel neuroprotective therapies. Several studies suggest that omega-3 polyunsaturated fatty acids (n -3 PUFA) might provide protection against brain damage. Here, we studied several experimental models of PD, using striatal neuronal cultures, striatal slices, and mice, to assess the neuroprotective effects of docosahexaenoic acid (DHA), the main n -3 PUFA in the brain, administered in its triglyceride form (TG-DHA). Hence, we determined the beneficial effects of TG-DHA on neural viability following 6-hydroxydopamine (6-OHDA)-induced neurotoxicity, a well-established PD model. We also implemented a novel mouse behavioral test, the beam walking test, to finely assess mouse motor skills following dopaminergic denervation. This test showed potential as a useful behavioral tool to assess novel PD treatments. Our results indicated that TG-DHA-mediated neuroprotection was independent of the net incorporation of PUFA into the striatum, thus suggesting a tight control of brain lipid homeostasis both in normal and pathological conditions. [ABSTRACT FROM AUTHOR]

Mesoporous Bioactive Glasses (MBGs) are a family of bioceramics widely investigated for their putative clinical use as scaffolds for bone regeneration. Their outstanding textural properties allow for high bioactivity when compared with other bioactive materials. Moreover, their great pore volumes allow these glasses to be loaded with a wide range of biomolecules to stimulate new bone formation. In this study, an MBG with a composition, in mol%, of 80% SiO2-15% CaO-5% P2O5 (Blank, BL) was compared with two analogous glasses containing 4% and 5% of ZnO (4ZN and 5ZN) before and after impregnationwith osteostatin, a C-terminal peptide froma parathyroid hormone-related protein (PTHrP107-111). Zn2+> ions were included in the glass for their bone growth stimulator properties, whereas osteostatin was added for its osteogenic properties. Glasses were characterized, and their cytocompatibility investigated, in pre-osteoblastic MC3T3-E1 cell cultures. The simultaneous additions of osteostatin and Zn2+> ions provoked enhanced MC3T3-E1 cell viability and a higher differentiation capacity, compared with either raw BL or MBGs supplemented only with osteostatin or Zn2+>. These in vitro results show that osteostatin enhances the osteogenic effect of Zn2+>-enriched glasses, suggesting the potential of this combined approach in bone tissue engineering applications. [ABSTRACT FROM AUTHOR]

The glycosylphosphatidylinositol-linked GDNF (glial cell derived neurotrophic factor) receptor alpha (GFRA), a coreceptor that recognizes the GDNF family of ligands, has a crucial role in the development and maintenance of the nervous system. Of the four identified GFRA isoforms, GFRA1 specifically recognizes GDNF and is involved in the regulation of proliferation, differentiation, and migration of neuronal cells. GFRA1 has also been implicated in cancer cell progression and metastasis. Recent findings show that GFRA1 can contribute to the development of chemoresistance in osteosarcoma. GFRA1 expression was induced following treatment of osteosarcoma cells with the popular anticancer drug, cisplatin and induction of GFRA1 expression significantly suppressed apoptosis mediated by cisplatin in osteosarcoma cells. GFRA1 expression promotes autophagy by activating the SRC-AMPK signaling axis following cisplatin treatment, resulting in enhanced osteosarcoma cell survival. GFRA1-induced autophagy promoted tumor growth in mouse xenograft models, suggesting a novel function of GFRA1 in osteosarcoma chemoresistance. [ABSTRACT FROM AUTHOR]