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23 results on '"Bhushan, Sakshi"'

3. Contributors

Author

Agbo, Chinazom P., primary, Aggarwal, Diwakar, additional, Ahmed, Sarfaraz, additional, Almeida, Tamires C., additional, Amjad, Saima, additional, Amparo, Tatiane R., additional, Arshad, Fareeha, additional, Attama, Anthony A., additional, Barve, Kalyani, additional, Bhushan, Sakshi, additional, Brandelli, Adriano, additional, Chaudhari, H.S., additional, Chauhan, Narendra Pal Singh, additional, Chinnam, Sampath, additional, Costa, Paulo C., additional, Delerue-Matos, Cristina, additional, Dhanka, Mukesh, additional, dos Santos, Orlando D.H., additional, Ferreira, Ana Sofia, additional, Garg, Vivek Kumar, additional, Ghosh, Arnab, additional, Gupta, Dhruv Sanjay, additional, Gupta, Manish, additional, Gupta, Vishal, additional, Hassan, Israr Ul, additional, Jadoun, Sapana, additional, Jain, Nishant K., additional, Joshi, Hemant, additional, Kaur, Ginpreet, additional, Kenechukwu, Franklin C., additional, Khan, Amreen, additional, Kiran, Pallavi, additional, Kulkarni, Prachi, additional, Kumar, Akshay, additional, Kumar, Manoj, additional, Kumar, Pawan, additional, Kumar, Rajiv, additional, Kumari, Vibha, additional, Londhe, Vaishali, additional, Lopes, Nathalie Almeida, additional, Luís, Ana Sofia, additional, Macedo, Catarina, additional, Mahdi, Abbas Ali, additional, Mbah, Chukwuemeka C., additional, Mehta, Jinal M., additional, Moin, Afrasim, additional, Naikoo, Gowhar Ahmad, additional, Nnamani, Petra O., additional, Nur, Hadi, additional, Oluwafemi, Oluwatobi S., additional, Onokala, Ozioma B., additional, Oyedeji, Adebola O., additional, Palaniappan, Arunkumar, additional, Pandey, Vaishnavi, additional, Parham, Seyedeh-Shirin, additional, Parham, Shokoh, additional, Parvez, Mohammad K., additional, Pinilla, Cristian Mauricio Barreto, additional, Jaquilin PJ, Rose, additional, Popat, R.R., additional, Prakash, Bhanu, additional, Prasad, Rajendra, additional, Raghuvanshi, Tanya Singh, additional, Rodrigues, Francisca, additional, Ruela, André Luis M., additional, Sak, Katrin, additional, Sandhiya, V., additional, Seibert, Janaína B., additional, Sen, Priya, additional, Shah, Rajvi, additional, Silva, Ana Margarida, additional, Singh, Prem Pratap, additional, de Souza, Gustavo Henrique B., additional, Srivastava, Rohit, additional, Thomas, Sabu, additional, Tuli, Hardeep Singh, additional, Ubaidulla, U., additional, Ugwueze, Mercy E., additional, Umeyor, Chukwuebuka E., additional, Uronnachi, Emmanuel M., additional, Yadav, Hemant K.S., additional, and Yerer, Mukerrem Betul, additional

Published
2023
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4. Phyto nanomedicine for cancer therapy

Author

Gupta, Dhruv Sanjay, primary, Kaur, Ginpreet, additional, Bhushan, Sakshi, additional, Sak, Katrin, additional, Garg, Vivek Kumar, additional, Aggarwal, Diwakar, additional, Joshi, Hemant, additional, Kumar, Pawan, additional, Yerer, Mukerrem Betul, additional, and Tuli, Hardeep Singh, additional

Published
2023
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10. Autophagy Induction by Scutellaria Flavones in Cancer: Recent Advances

Author

Tuli, Hardeep Singh, primary, Bhushan, Sakshi, additional, Kumar, Ajay, additional, Aggarwal, Poonam, additional, Sak, Katrin, additional, Ramniwas, Seema, additional, Vashishth, Kanupriya, additional, Behl, Tapan, additional, Rana, Rashmi, additional, Haque, Shafiul, additional, and Prieto, Miguel A., additional

Published
2023
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11. Natural flavonoids exhibit potent anticancer activity by targeting microRNAs in cancer: A signature step hinting towards clinical perfection

Author

Tuli, Hardeep Singh, primary, Garg, Vivek Kumar, additional, Bhushan, Sakshi, additional, Uttam, Vivek, additional, Sharma, Uttam, additional, Jain, Aklank, additional, Sak, Katrin, additional, Yadav, Vikas, additional, Lorenzo, Jose M., additional, Dhama, Kuldeep, additional, Behl, Tapan, additional, and Sethi, Gautam, additional

Published
2023
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15. In vitroAntioxidant, Antimutagenic and Anti-hemolytic Potency of Allyl Isothiocyanate: A Natural Molecule

Author

Bhushan, Sakshi, Rajput, Sneh, Sharma, Deepak, Kaur, Tajinder, Dhar, Manoj K., and Arora, Saroj

Abstract

AbstractThe cruciferous vegetables are richest sources of isothiocyanates and among them, allyl isothiocyanate (AITC) is one of the major constituents. It has been known to possess various activities of therapeutic interest. Keeping this in view, the present study was planned to investigate antioxidant capacity of AITC using Cupric Reducing Antioxidant Capacity (CUPRAC) Assay, 2, 2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assay, β-Carotene bleaching (BCB) assay and superoxide anion scavenging assay. The antimutagenic potency of AITC was determined by modifying Vibrio harveyibioluminescence assay against direct acting mutagen 4-nitro-o-phenylenediamine (NPD) and indirect acting mutagens 2-acetylaminofluorene (2-AAF), 7,12-Dimethylbenz[a]anthracene (DMBA) in presence and absence of S9. Furthermore, the antihemolytic activity was evaluated using hemolysis assay. Among the different activities carried out, it was observed that AITC exhibited efficient antimutagenic potential against direct acting mutagen NPD and indirect acting mutagens 2-AAF and DMBA in the presence as well as absence of S9 fraction in Vibrio harveyibioluminescence assay. Overall, our results established the efficiency of AITC to act as strong antimutagenic agent, efficient anti-hemolytic agent and mild antioxidant agent thus, making AITC an interesting candidate to be further explored for drug discovery.

Published
2021
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21. Extraction, profiling and bioactivity analysis of volatile glucosinolates present in oil extract of <italic>Brassica juncea</italic> var. <italic>raya</italic>.

Author

Bassan, Priyanka, Bhushan, Sakshi, Kaur, Tajinder, Arora, Rohit, Arora, Saroj, and Vig, Adarsh Pal

Abstract

Cruciferous vegetables are rich source of glucosinolates (GSLs), which in presence of myrosinase enzyme cause hydrolytic cleavage and result in different hydrolytic products like isothiocyanates, thiocyanates, nitriles and epinitriles. The GSLs hydrolytic products are volatile compounds, which are known to exhibit bioactivities like antioxidant, fungicidal, bioherbicidal and anticancer. Among the Brassicaceae family, Brassica juncea is very well known for high content of GSLs. In the present study, the isolation of volatile oil of B. juncea var. raya was done by hydrodistillation method using clevenger apparatus and further there extraction was done by solvents ethyl acetate and dichloromethane. The volatile compounds present in the extract were analysed by gas chromatography/gas chromatography-mass spectrometry (GC/GC-MS). Fatty acid esters, sulphur and/or nitrogen compounds, carbonyl compounds and some other volatile compounds were also identified. Besides the analytical studies, the extracts were analysed for their bioactivities including radical scavenging activity by using DNA nicking assay and cytotoxic effect using different human cancer cell lines viz. breast (MCF-7 and MDA-MB-231), prostate (PC-3), lung (A-549), cervix (HeLa) and colon (HCT116) by MTT assay. The oil extracts were efficiently able to reduce the increase of cancer cells in a dose-dependent manner. Among all cell lines, the most effective anticancer activity was observed in case of breast (MCF-7) cancer cell line. So, MCF-7 cells were used for further mechanistic studies for analysing the mechanism of anticancer activity. Confocal microscopy was done for analysing morphological changes in the cells and the images confirmed the features typical of apoptosis. For evaluating the mode of cell death, spectrofluorometric determination of reactive oxygen species (ROS) and mitochondrial membrane potential (MMP) was done. The volatile oil extract treated MCF-7 cells had a significant increase in number of ROS, also there was a rise in percentage of cells with increased disruption of MMP. So, the present study marks necessary indication that B. juncea (raya) oil extracts significantly induces apoptosis in all the above mentioned cancer cells lines through a ROS-mediated mitochondrial pathway and thus play a remarkable role in death of cancer cells. [ABSTRACT FROM AUTHOR]

Published
2018
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23. UWW lifts suspension of WFI; Sports Ministry to follow?

Subjects
Sports associations, Business, international, Sports, sporting goods and toys industry
Abstract

Byline: SportzPower Team Wrestling's world governing body on Tuesday lifted the suspension it imposed on the Wrestling Federation of India 'with immediate effect'. The development likely paves the way for [...]

Published
2024

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