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6. SARS-COV-2 Pandemic : How to Maintain a COVID-free Hospital

Author

Bassanello, Marco, Farencena, Aldo, Pasqualini, Maria Teresa, D´Aquino, Maurizio, Geretto, Matteo, Tegon, Antonio, and Coli, Ugo

Subjects
Medical
Abstract

The emergence of severe acute respiratory syndrome type 2 coronavirus (SARS-CoV-2) and its complications have demonstrated the devastating impact of a new infectious pathogen since the first months of 2020, especially on Health Systems. The work to maintain a COVID-free hospital in terms of reorganization of operational processes and surveillance against SARS-CoV-2 has allowed us to maintain the structure suitable for activities for non-positive patients. The commitment related to this reorganization (not only in terms of costs) is largely satisfied by the responses to the health needs of non-COVID patients. The results obtained during the First Pandemic phase at the Giovanni XXIII Hospital in Monastier di Treviso have allowed the maintenance of the status of a COVID-free hospital. These results are supported by multiple studies in other parts of the world.

Published
2022

13. Il trauma epatico: dal trattamento conservativo al trapianto di fegato Analisi di centro

Author

Bassanello, Marco

Subjects
trattamento conservativo del trauma epatico, Settore MED/18 - Chirurgia Generale, Trauma epatico, trattamento conservativo del trauma epatico, trattamento chirurgico del trauma epatico, trapianto di fegato per trauma epatico, trattamento chirurgico del trauma epatico, Trauma epatico, trapianto di fegato per trauma epatico
Published
2008

14. Isoniazid-related fulminant hepatic failure in a child: assessment of the native liver's early regeneration after auxiliary partial orthotopic liver transplantation

Author

Cillo, Umberto, primary, Bassanello, Marco, additional, Vitale, Alessandro, additional, D'Antiga, Lorenzo, additional, Zanus, Giacomo, additional, Brolese, Alberto, additional, Burra, Patrizia, additional, Ciarleglio, Francesco Antonio, additional, Guariso, Graziella, additional, Zancan, Lucia, additional, Guido, Maria, additional, and D'Amico, Davide Francesco, additional

Published
2004
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15. Clinical significance of alpha-fetoprotein mRNA in blood of patients with hepatocellular carcinoma

Author

Cillo, Umberto, primary, Navaglia, Filippo, additional, Vitale, Alessandro, additional, Molari, Alfiero, additional, Basso, Daniela, additional, Bassanello, Marco, additional, Brolese, Alberto, additional, Zanus, Giacomo, additional, Montin, Umberto, additional, D'Amico, Francesco, additional, Ciarleglio, Francesco Antonio, additional, Carraro, Amedeo, additional, Bridda, Alessio, additional, Burra, Patrizia, additional, Carraro, Paolo, additional, Plebani, Mario, additional, and D'Amico, Davide Francesco, additional

Published
2004
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16. Growth hormone/insulin-like growth factor 1 axis recovery after liver transplantation: A preliminary prospective study

Author

Bassanello, Marco, primary, De Palo, Elio Franco, additional, Lancerin, Federica, additional, Vitale, Alessandro, additional, Gatti, Rosalba, additional, Montin, Umberto, additional, Ciarleglio, Francesco Antonio, additional, Senzolo, Marco, additional, Burra, Patrizia, additional, Brolese, Alberto, additional, Zanus, Giacomo, additional, D'Amico, Davide Francesco, additional, and Cillo, Umberto, additional

Published
2004
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18. Multimodal therapy before liver transplantation for hepatocellular carcinoma

Author

Vitale, Alessandro, Brolese, Alberto, Zanus, Giacomo, Bassanello, Marco, Montin, Umberto, Gringeri, Enrico, D’Amico, Francesco, Ciarleglio, Francesco Antonio, Carraro, Amedeo, Cappuzzo, Gianluca, Bridda, Alessio, D’Amico, Davide Francesco, and Cillo, Umberto

Subjects
LIVER transplantation, LIVER cancer patients, LIVER cancer, DRUG therapy, THROMBOSIS, TUMORS
Abstract

Abstract: Background:: The use of orthotopic liver transplantation (OLT) for the treatment of patients with hepatocellular carcinoma (HCC) remains controversial because of the risk of both exclusion from the waiting list due to tumor progression and post OLT HCC recurrence. The aim of the present study was to evaluate the effect of an aggressive HCC treatment during the waiting list time on overall and recurrence-free survival of HCC transplanted patients in a single institutional study. Methods:: Since 1991, 40 HCC patients joined the OLT-waiting list. Poorly differentiated HCC cases were excluded, while size and number of nodules were not considered as absolute selection criteria. In all, 90% of the study group had HCC treatment while on the waiting list (transarterial chemoembolization, percutaneous therapies, chemotherapy). Results:: Only one patient (2.5%) was removed from the waiting list after developing neoplastic portal thrombosis 3 months after listing, while 33 (82.5%) underwent to OLT after a median waiting list time of 11 months (range 3–16 months). On histological examination, 42% of the group did not meet the “Milan criteria” and 42% were pTNM stages III and IV. The median follow-up was 42 months. The 5-year actuarial survival rate was 64% and recurrence-free survival was 91%. HCC recurred in only two patients (6%). Conclusions:: The use of routine pre-OLT tumor grading and of an aggressive HCC treatment during the waiting list, in our experience, resulted in a very low risk of pre OLT tumor progression leading to exclusion and of post OLT HCC recurrence. [Copyright &y& Elsevier]

Published
2005
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19. Case Report Syngeneic Living-Donor Liver Transplantation for Hemangioendothelioma: A Clinical Model for Studying Liver Regeneration

Author

Cillo, Umberto, Vitale, Alessandro, Brolese, Alberto, Zanus, Giacomo, Bassanello, Marco, Montin, Umberto, D'Amico, Francesco, Ciarleglio, Francesco Antonio, Iurilli, Vincenzo, Carraro, Paolo, Grigoletto, Francesco, Plebani, Mario, and D'Amico, Davide Francesco

Abstract

A 22-year-old Caucasian patient underwent living-donor liver transplantation (LDLT) for hepatic hemangioendothelioma in a healthy liver. The organ donor was his monozygotic twin brother. Surgery was uneventful in both donor and recipient, who received the same postoperative treatment (i.e. no immunosuppression for the recipient). Although both donor and recipient achieved a full liver function recovery, the volume of the recipient's graft increased much more than the donor's residual liver in the first postoperative month (1.6-fold vs. 1.2-fold). This different growth rate correlated with growth hormone (GH)/insulin growth factor (IGF) axis dynamics: the donor had significantly lower insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2) and insulin-like growth factor binding protein 3 (IGFBP-3) values than the recipient on postoperative days (POD) 3–30, although they had similar GH values. Other potential regenerative factors, e.g. tumor necrosis α, interleukin 6 (IL-6), insulin and C peptide did not correlate with liver regeneration rate. The particular endocrine picture of the graft may be explained by a modified GH-hepatocyte interaction due to cold ischemia during preservation resulting in a higher IGF production. Whether this is a potential molecular tool by means of which transplanted partial livers promote their regeneration remains to be seen in a larger number of patients.

Published
2005
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