Effects of Risperidone on Aberrant Behavior of Persons with Developmental Disabilities: I. A Double-Blind Crossover Study Using Multiple Measures.

The efficacy of the atypical antipsychotic risperidone was evaluated in the treatment of aberrant behavior (e.g., aggression, self-injury) in 20 individuals with developmental disabilities. The study, a double-blind crossover design, identified 50 percent of participants as responders. Naturalistic observations of five participants showed that risperidone was effective in reducing aberrant behavior in four individuals. (Contains references.) (Author/DB)