Back to Search Start Over

Lasting Enhancements in Neural Efficiency by Multi-Session Transcranial Direct Current Stimulation during Working Memory Training

Authors :
Yufeng Ke
Shuang Liu
Long Chen
Xiashuang Wang
Dong Ming
Source :
npj Science of Learning. 2023 8.
Publication Year :
2023

Abstract

The neural basis for long-term behavioral improvements resulting from multi-session transcranial direct current stimulation (tDCS) combined with working memory training (WMT) remains unclear. In this study, we used task-related electroencephalography (EEG) measures to investigate the lasting neurophysiological effects of anodal high-definition (HD)-tDCS applied over the left dorsolateral prefrontal cortex (dlPFC) during a challenging WMT. Thirty-four healthy young adults were randomized to sham or active tDCS groups and underwent ten 30-minute training sessions over ten consecutive days, preceded by a pre-test and followed by post-tests performed one day and three weeks after the last session, respectively, by performing high-load WM tasks along with EEG recording. Multi-session HD-tDCS significantly enhanced the behavioral benefits of WMT. Compared to the sham group, the active group showed facilitated increases in theta, alpha, beta, and gamma task-related oscillations at the end of training and significantly increased P300 response 3 weeks post-training. Our findings suggest that applying anodal tDCS over the left dlPFC during multi-session WMT can enhance the behavioral benefits of WMT and facilitate sustained improvements in WM-related neural efficiency.

Details

Language :
English
ISSN :
2056-7936
Volume :
8
Database :
ERIC
Journal :
npj Science of Learning
Publication Type :
Academic Journal
Accession number :
EJ1431702
Document Type :
Journal Articles<br />Reports - Research
Full Text :
https://doi.org/10.1038/s41539-023-00200-y