An Introduction to Modelling through a Microbial Interaction Application

This paper describes a teaching experiment in a Numerical Methods course for Master of Science students. The experiment uses scientific papers to develop modelling studies in the context of wine fermentation microbial interactions. The course involves theoretical and laboratory classes that focus on implementing numerical methods using Matlab for Initial Value Problems and Boundary Value Problems. The students are asked to formalise the mathematical model and build their own experiments using the information provided in the papers. Additionally, a parameter estimation experiment is organised, which involves generating synthetic data and computing noisy data to estimate the natural death rate of sensitive yeast. The results show that data noise significantly affects the parameter estimate and that scaling the data can help reduce the impact of measurement errors. The presented results can be used to investigate other possible assignments, such as how the evaluation of the Jacobian affects the estimation performance and compare different optimisation algorithms.