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What Is in Your Wallet? Quantitation of Drugs of Abuse on Paper Currency with a Rapid LC-MS/MS Method
- Source :
-
Journal of Chemical Education . Oct 2017 94(10):1522-1526. - Publication Year :
- 2017
-
Abstract
- Laboratory experiments were developed to introduce students to the quantitation of drugs of abuse by high performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). Undergraduate students were introduced to internal standard quantitation and the LC-MS/MS method optimization for cocaine. Cocaine extracted from paper currency was analyzed with a simple and rapid LC-MS/MS method. Students in advanced laboratories determined the amount of amphetamine, methamphetamine, and oxycodone on currency in addition to cocaine. The LC-MS/MS method has a short run time (2.5 min) to allow for a high throughput of student samples.
Details
- Language :
- English
- ISSN :
- 0021-9584
- Volume :
- 94
- Issue :
- 10
- Database :
- ERIC
- Journal :
- Journal of Chemical Education
- Publication Type :
- Academic Journal
- Accession number :
- EJ1159606
- Document Type :
- Journal Articles<br />Reports - Descriptive
- Full Text :
- https://doi.org/10.1021/acs.jchemed.7b00196