Back to Search
Start Over
Clinical Application of DDM/rhBMP-2 in Implant Dentistry
- Publication Year :
- 2019
- Publisher :
- 2019.
-
Abstract
- Recombinant human bone morphogenetic protein-2 (rhBMP-2) is well-known osteoinductive growth factors that can be used along with various carriers. Demineralized dentin matrix (DDM) that has osteoinductive and osteoconductive capacities was developed as potential candidate for rhBMP-2 carrier that has its endogenous growth factors and fulfils the requirements such as controlled release kinetics, biocompatibility, biodegradabilities and bone forming capacity. DDM loaded with rhBMP-2 (DDM/rhBMP-2) have been subjected to in vitro, in vivo studies for the purpose of proving the clinical safety and efficacy. Recently the clinical trials and outcomes of DDM/rhBMP-2 have also proved this composite to be safe and efficient in terms of enhanced bone formation, remodeling capacity and reduced concentration of rhBMP-2 in implant dentistry in Korea. This chapter will introduce the clinical application of DDM/rhBMP-2 in implant dentistry based on the related experimental and clinical researches.
- Subjects :
- Medical
Subjects
Details
- Language :
- English
- Database :
- Open Research Library
- Accession number :
- edsors.cfc62516.4468.4d09.b5e2.3ad9ec2a1001
- Document Type :
- CHAPTER