Back to Search Start Over

Chemoenzymatic Dynamic Kinetic Resolution of Primary Benzylic Amines using Pd0-CalB CLEA as a Biohybrid Catalyst

Authors :
Universidad de Sevilla. Departamento de Química orgánica
Swedish Research Council
Knut and Alice Wallenberg Foundation
Gustafson, Karl P.J.
Görbe, Tamás
Gonzalo Calvo, Gonzalo de
Yuan, Ning
Schreiber, Cynthia L.
Shchukarev, Andrey
Tai, Cheuk Wai
Persson, Ingmar
Zou, Xiaodong
Bäckvall, Jan E.
Universidad de Sevilla. Departamento de Química orgánica
Swedish Research Council
Knut and Alice Wallenberg Foundation
Gustafson, Karl P.J.
Görbe, Tamás
Gonzalo Calvo, Gonzalo de
Yuan, Ning
Schreiber, Cynthia L.
Shchukarev, Andrey
Tai, Cheuk Wai
Persson, Ingmar
Zou, Xiaodong
Bäckvall, Jan E.
Publication Year :
2019

Abstract

Herein, we report on the use a biohybrid catalyst consisting of palladium nanoparticles immobilized on cross-linked enzyme aggregates of lipase B of Candida antarctica (CalB CLEA) for the dynamic kinetic resolution (DKR) of benzylic amines. A set of amines were demonstrated to undergo an efficient DKR and the recyclability of the catalysts was studied. Extensive efforts to further elucidate the structure of the catalyst are presented.

Details

Database :
OAIster
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1458404303
Document Type :
Electronic Resource