Expedited Scientific Research and Reporting (ESRO) at KCE

130 p.
ill.
LIST OF FIGURES 6 -- LIST OF TABLES 7 -- LIST OF ABBREVIATIONS 8 -- SCIENTIFIC REPORT 9 -- 1 RATIONALE 9 -- 2 OBJECTIVES & METHODS 10 -- 3 GENERAL ESRO FRAMEWORK AT KCE 11 -- 3.1 INTRODUCTION 11 -- 3.2 SCREENING AND RANKING RESEARCH REQUESTS 13 -- 3.2.1 Regular annual call 14 -- 3.2.2 Urgent requests 14 -- 3.3 DESIGNING ESRO METHODS IN THE RESEARCH PROTOCOL 18 -- 3.3.1 Project scoping phase 19 -- 3.3.2 Protocol challenge phase 20 -- 3.4 HAVING HUMAN RESOURCES READILY AVAILABLE FOR AD HOC REQUESTS 20 -- 3.5 WHEN IS IT APPROPRIATE TO ABRIDGE OR SKIP THE EXPERT AND STAKEHOLDER MEETINGS? 21 -- 3.6 WHEN IS IT APPROPRIATE TO SKIP PROPOSING CLINICAL OR POLICY RECOMMENDATIONS? 21 -- 3.7 EXPEDITING THE PEER REVIEW OF SCIENTIFIC REPORTS 22 -- 3.8 EXPEDITING THE PEER REVIEW OF REPORT SYNTHESES 23 -- 3.9 REPORTING 23 -- 3.9.1 Synthesis and translation 23 -- 3.9.2 Labelling ESRO reports 23 -- 4 EXPEDITED LITERATURE REVIEWS 24 -- 4.1 WHEN IS IT APPROPRIATE TO SEARCH ONLY MEDLINE? 24 -- 4.1.1 Expedited reviews of RCTs 25 -- 4.1.2 Expedited reviews of non-randomised studies 25 -- 4.2 WHEN IS IT APPROPRIATE TO LIMIT THE SEARCH TO CORE JOURNALS? 26 -- 4.3 WHEN IS IT APPROPRIATE TO OPTIMISE THE PRECISION OF THE SEARCH STRATEGY? 26 -- 4.3.1 Constructing the optimised search strategy 26 -- 4.3.2 Quality assurance 27 -- 4.4 WHEN IS IT APPROPRIATE TO SKIP THE RETRIEVAL OF GREY EVIDENCE? 27 -- 4.5 WHEN IS IT APPROPRIATE TO RELY ON ONE SINGLE REVIEWER? 29 -- 4.6 WHEN IS IT APPROPRIATE TO INCLUDE (PARTLY OR MOSTLY) SURROGATE OR MODELLING STUDIES? 29 -- 4.6.1 Surrogate-based studies 29 -- 4.6.2 Modelling studies 31 -- 4.7 WHEN IS IT APPROPRIATE TO BASE THE REVIEW (PARTLY OR MOSTLY) ON INTERIM RESULTS? 31 -- 4.8 WHEN IS IT APPROPRIATE TO RELY ON A PUBLISHED SYSTEMATIC REVIEW, WITH OR WITHOUT UPDATE? 33 -- 4.8.1 Background 33 -- 4.8.2 Deciding when and whether to conduct an update of an existing systematic review 34 -- 4.8.3 Planning and conducting the update of an existing systematic review 39