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Ultra-Early and Short-Term Tranexamic Acid Treatment in Patients With Good- and Poor-Grade Aneurysmal Subarachnoid Hemorrhage
- Source :
- Tjerkstra, Maud A; Post, René; Germans, Menno R; Vergouwen, Mervyn D I; Jellema, Korne; Koot, Radboud W; Kruyt, Nyika D; Wolfs, Jasper F C; De Beer, Frits C; Kieft, Hans H; Nanda, Dharmin; Van Der Pol, Bram; Roks, Gerwin; De Beer, Frank; Reichman, Loes J A; Brouwers, Paul J A M; Kwa, Vincent I H; Van Der Ree, Taco C; Bienfait, Henri P; Boogaarts, Hieronymus D; Klijn, Catharina J; Visser, Victoria; van den Berg, René; Coert, Bert A; Horn, Janneke; Majoie, Charles B L M; Rinkel, Gabriël J E; Roos, Yvo B W E M; Vandertop, W Peter; Verbaan, Dagmar (2024). Ultra-Early and Short-Term Tranexamic Acid Treatment in Patients With Good- and Poor-Grade Aneurysmal Subarachnoid Hemorrhage. Neurology, 102(12):e209169.
- Publication Year :
- 2024
-
Abstract
- The results of the ULTRA trial showed that ultra-early and short-term treatment with tranexamic acid (TXA) does not improve clinical outcome after aneurysmal subarachnoid hemorrhage (aSAH). Possibly, the lack of a beneficial effect in all patients with aSAH is masked by antagonistic effects of TXA in certain subgroups. In this post hoc subgroup analysis, we investigated the effect of TXA on clinical outcome in patients with good-grade and poor-grade aSAH.
Details
- Database :
- OAIster
- Journal :
- Tjerkstra, Maud A; Post, René; Germans, Menno R; Vergouwen, Mervyn D I; Jellema, Korne; Koot, Radboud W; Kruyt, Nyika D; Wolfs, Jasper F C; De Beer, Frits C; Kieft, Hans H; Nanda, Dharmin; Van Der Pol, Bram; Roks, Gerwin; De Beer, Frank; Reichman, Loes J A; Brouwers, Paul J A M; Kwa, Vincent I H; Van Der Ree, Taco C; Bienfait, Henri P; Boogaarts, Hieronymus D; Klijn, Catharina J; Visser, Victoria; van den Berg, René; Coert, Bert A; Horn, Janneke; Majoie, Charles B L M; Rinkel, Gabriël J E; Roos, Yvo B W E M; Vandertop, W Peter; Verbaan, Dagmar (2024). Ultra-Early and Short-Term Tranexamic Acid Treatment in Patients With Good- and Poor-Grade Aneurysmal Subarachnoid Hemorrhage. Neurology, 102(12):e209169.
- Notes :
- application/pdf, info:doi/10.5167/uzh-260111, English, English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1443058927
- Document Type :
- Electronic Resource