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The Uniqueness of Albumin as a Carrier in Nano Drug Delivery

Authors :
Yash Gupta
Rai, Vishal
Singh, Anushka
Khan, Soban
Bano, Nisha
Yadav, Reena
Yash Gupta
Rai, Vishal
Singh, Anushka
Khan, Soban
Bano, Nisha
Yadav, Reena
Source :
Journal for Research in Applied Sciences and Biotechnology; Vol. 3 No. 1 (2024): February Issue; 7-11; 2583-4053
Publication Year :
2024

Abstract

The quest for precision medicine hinges on targeted drug delivery, minimizing off-target effects while maximizing therapeutic impact. Among nanocarriers, albumin – the most abundant protein in human blood – emerges as a uniquely biocompatible stealth bomber. Its inherent advantages, including exceptional biodegradability, prolonged circulation, and natural affinity for diseased tissues, perfectly align with the goals of personalized medicine. Albumin readily solubilizes poorly soluble drugs, enhancing bioavailability and broadening the therapeutic arsenal. Its versatile surface allows for targeted modifications, enabling dual diagnosis and treatment (theranostics) tailored to individual needs. While challenges remain in optimizing drug loading and targeting specificity, albumin-based nanocarriers hold immense promise for revolutionizing personalized healthcare, delivering potent therapeutics with pinpoint accuracy. The burgeoning field of nanodrug delivery seeks to redefine therapeutic landscapes by engineering nanoscale carriers that meticulously deliver potent drugs to their designated targets, minimizing systemic exposure and maximizing therapeutic efficacy. This pursuit aligns perfectly with the burgeoning field of precision medicine, where personalized treatments demand exquisite control over drug delivery. Within this intricate choreography, albumin, the abundant and versatile protein resident in human plasma, emerges as a maestro, orchestrating a symphony of advantages that make it a prime candidate for nanocarrier construction.

Details

Database :
OAIster
Journal :
Journal for Research in Applied Sciences and Biotechnology; Vol. 3 No. 1 (2024): February Issue; 7-11; 2583-4053
Notes :
application/pdf, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1423747145
Document Type :
Electronic Resource