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Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring:results of a randomised, placebo-controlled trial

Authors :
Tweyongyere, Robert
Mawa, Patrice A.
Kihembo, Macklyn
Jones, Frances M.
Webb, Emily L.
Cose, Stephen
Dunne, David W.
Vennervald, Birgitte J
Elliott, Alison M.
Tweyongyere, Robert
Mawa, Patrice A.
Kihembo, Macklyn
Jones, Frances M.
Webb, Emily L.
Cose, Stephen
Dunne, David W.
Vennervald, Birgitte J
Elliott, Alison M.
Source :
Tweyongyere , R , Mawa , P A , Kihembo , M , Jones , F M , Webb , E L , Cose , S , Dunne , D W , Vennervald , B J & Elliott , A M 2011 , ' Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring : results of a randomised, placebo-controlled trial ' , B M C Infectious Diseases , vol. 11 , no. 234 .
Publication Year :
2011

Abstract

Offspring of women with schistosomiasis may exhibit immune responsiveness to schistosomes due to in utero sensitisation or trans-placental transfer of antibodies. Praziquantel treatment during pregnancy boosts maternal immune responses to schistosome antigens and reduces worm burden. Effects of praziquantel treatment during pregnancy on responses among offspring are unknown.

Details

Database :
OAIster
Journal :
Tweyongyere , R , Mawa , P A , Kihembo , M , Jones , F M , Webb , E L , Cose , S , Dunne , D W , Vennervald , B J & Elliott , A M 2011 , ' Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring : results of a randomised, placebo-controlled trial ' , B M C Infectious Diseases , vol. 11 , no. 234 .
Notes :
application/pdf, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1408245404
Document Type :
Electronic Resource