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Supplementary Information: Cell-specific vulnerability to metabolic failure: the crucial role of parvalbumin expressing neurons in creatine transporter deficiency

Authors :
Ghirardini, Elsa
Sagona, Giulia
Marquez-Galera, Angel
Calugi, Francesco
Navarrón, Carmen M.
Cacciante, Francesco
Chen, Siwei
Di Vetta, Federica
Dadà, Lorenzo
Mazziotti, Raffaele
Lupori, Leonardo
Putignano, Elena
Baldi, Pierre
López-Atalaya, José P.
Pizzorusso, Tommaso
Baroncelli, Laura
Ghirardini, Elsa
Sagona, Giulia
Marquez-Galera, Angel
Calugi, Francesco
Navarrón, Carmen M.
Cacciante, Francesco
Chen, Siwei
Di Vetta, Federica
Dadà, Lorenzo
Mazziotti, Raffaele
Lupori, Leonardo
Putignano, Elena
Baldi, Pierre
López-Atalaya, José P.
Pizzorusso, Tommaso
Baroncelli, Laura
Publication Year :
2023

Abstract

Additional file 1: Supplementary Materials and Methods and Supplementary figures S1, S2, S3, S4, S5, S6, S7, S8. Additional file 2: Table S1. List of differentially expressed genes in bulk RNA-seq. Additional file 3: Table S2. Quantitative PCR validation of top differentially-expressed genes. Additional file 4: Table S3. Gene Ontology analysis for biological process for up- and downregulated genes in bulk RNA-seq. Additional file 5: Table S4. Gene Ontology analysis for cellular component for up- and downregulated genes in bulk RNA-seq. Additional file 6: Table S5. Clusters of protein-protein interactions (PPI) for the corresponding proteins of up- and downregulated genes in bulk RNA-seq. Additional file 7: Table S6. List of population marker genes used for supervised clustering analysis of snRNA-seq data. Additional file 8: Table S7. Quantification of cells belonging to each of the major population clusters in snRNA-seq data. Additional file 9: Table S8. List of differentially expressed genes in major sn-RNAseq clusters. Additional file 10: Table S9. Gene Ontology analysis for biological process for up- and downregulated genes in major sn-RNAseq clusters. Additional file 11: Table S10. Gene Ontology analysis for cellular component for up- and downregulated genes in major sn-RNAseq clusters. Additional file 12: Table S11. Number of reads for each biological replicate in bulk RNA-seq. Additional file 13: Table S12. Primer sequences for qPCR.

Details

Database :
OAIster
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1406079801
Document Type :
Electronic Resource