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Individual participant data meta-analysis to compare EPDS accuracy to detect major depression with and without the self-harm item

Authors :
Qiu, Xia
Wu, Yin
Sun, Ying
Levis, Brooke
Tian, Jizhou
Boruff, Jill T.
Cuijpers, Pim
Ioannidis, John P. A.
Markham, Sarah
Ziegelstein, Roy C.
Vigod, Simone N.
Benedetti, Andrea
Thombs, Brett
He, Chen
Krishnan, Ankur
Bhandari, Parash Mani
Neupane, Dipika
Negeri, Zelalem
Imran, Mahrukh
Rice, Danielle B.
Azar, Marleine
Chiovitti, Matthew J.
Gilbody, Simon A.
Kloda, Lorie B.
Patten, Scott D.
Mitchell, Nicholas
Alvarado, Ruben
Barnes, Jacqueline
Beck, Cheryl Tatano
Bindt, Carola
Correa, Humberto
Castro e Couto, Tiago
Chorwe-Sungani, Genesis
Eapen, Valsamma
Favez, Nicolas
Felice, Ethel
Fellmeth, Gracia
Fernandes, Michelle
Field, Sally
Figueiredo, Barbara
Fisher, Jane R. W.
Green, Eric P.
Honikman, Simone
Howard, Louise M.
Kettunen, Pirjo A.
Kohlhoff, Jane
Kozinszky, Zoltan
Leonardou, Angeliki A.
Maes, Michael
Martinez, Pablo
Rados, Sandra Nakic
Nishi, Daisuke
Pawlby, Susan J.
Rochat, Tamsen J.
Rowe, Heather J.
Sharp, Deborah J.
Skalkidou, Alkistis
Smith-Nielsen, Johanne
Stein, Alan
Su, Kuan-Pin
Sundström Poromaa, Inger
Tadinac, Meri
Tandon, S. Darius
Tendais, Iva
Toereki, Annamaria D.
Tran, Thach
Trevillion, Kylee
Turner, Katherine S.
Vaever, Mette
van Heyningen, Thandi M.
Vega-Dienstmaier, Johann
Wynter, Karen A.
Yonkers, Kimberly
Qiu, Xia
Wu, Yin
Sun, Ying
Levis, Brooke
Tian, Jizhou
Boruff, Jill T.
Cuijpers, Pim
Ioannidis, John P. A.
Markham, Sarah
Ziegelstein, Roy C.
Vigod, Simone N.
Benedetti, Andrea
Thombs, Brett
He, Chen
Krishnan, Ankur
Bhandari, Parash Mani
Neupane, Dipika
Negeri, Zelalem
Imran, Mahrukh
Rice, Danielle B.
Azar, Marleine
Chiovitti, Matthew J.
Gilbody, Simon A.
Kloda, Lorie B.
Patten, Scott D.
Mitchell, Nicholas
Alvarado, Ruben
Barnes, Jacqueline
Beck, Cheryl Tatano
Bindt, Carola
Correa, Humberto
Castro e Couto, Tiago
Chorwe-Sungani, Genesis
Eapen, Valsamma
Favez, Nicolas
Felice, Ethel
Fellmeth, Gracia
Fernandes, Michelle
Field, Sally
Figueiredo, Barbara
Fisher, Jane R. W.
Green, Eric P.
Honikman, Simone
Howard, Louise M.
Kettunen, Pirjo A.
Kohlhoff, Jane
Kozinszky, Zoltan
Leonardou, Angeliki A.
Maes, Michael
Martinez, Pablo
Rados, Sandra Nakic
Nishi, Daisuke
Pawlby, Susan J.
Rochat, Tamsen J.
Rowe, Heather J.
Sharp, Deborah J.
Skalkidou, Alkistis
Smith-Nielsen, Johanne
Stein, Alan
Su, Kuan-Pin
Sundström Poromaa, Inger
Tadinac, Meri
Tandon, S. Darius
Tendais, Iva
Toereki, Annamaria D.
Tran, Thach
Trevillion, Kylee
Turner, Katherine S.
Vaever, Mette
van Heyningen, Thandi M.
Vega-Dienstmaier, Johann
Wynter, Karen A.
Yonkers, Kimberly
Publication Year :
2023

Abstract

Item 10 of the Edinburgh Postnatal Depression Scale (EPDS) is intended to assess thoughts of intentional self-harm but may also elicit concerns about accidental self-harm. It does not specifically address suicide ideation but, nonetheless, is sometimes used as an indicator of suicidality. The 9-item version of the EPDS (EPDS-9), which omits item 10, is sometimes used in research due to concern about positive endorsements of item 10 and necessary follow-up. We assessed the equivalence of total score correlations and screening accuracy to detect major depression using the EPDS-9 versus full EPDS among pregnant and postpartum women. We searched Medline, Medline In-Process and Other Non-Indexed Citations, PsycINFO, and Web of Science from database inception to October 3, 2018 for studies that administered the EPDS and conducted diagnostic classification for major depression based on a validated semi-structured or fully structured interview among women aged 18 or older during pregnancy or within 12 months of giving birth. We conducted an individual participant data meta-analysis. We calculated Pearson correlations with 95% prediction interval (PI) between EPDS-9 and full EPDS total scores using a random effects model. Bivariate random-effects models were fitted to assess screening accuracy. Equivalence tests were done by comparing the confidence intervals (CIs) around the pooled sensitivity and specificity differences to the equivalence margin of delta = 0.05. Individual participant data were obtained from 41 eligible studies (10,906 participants, 1407 major depression cases). The correlation between EPDS-9 and full EPDS scores was 0.998 (95% PI 0.991, 0.999). For sensitivity, the EPDS-9 and full EPDS were equivalent for cut-offs 7-12 (difference range - 0.02, 0.01) and the equivalence was indeterminate for cut-offs 13-15 (all differences - 0.04). For specificity, the EPDS-9 and full EPDS were equivalent for all cut-offs (difference range 0.00, 0.01). The EPDS-9 performs

Details

Database :
OAIster
Notes :
application/pdf, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1399991900
Document Type :
Electronic Resource
Full Text :
https://doi.org/10.1038.s41598-023-29114-w