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Clonal Patterns Between Pouch Neoplasia and Prior Colorectal Neoplasia in Inflammatory Bowel Disease Patients:An Exploratory Cohort Study

Authors :
Te Groen, Maarten
Derikx, Lauranne A.A.P.
van Lierop, Lisa
Ylstra, Bauke
Hoentjen, Frank
Nagtegaal, Iris D.
Simmer, Femke
Te Groen, Maarten
Derikx, Lauranne A.A.P.
van Lierop, Lisa
Ylstra, Bauke
Hoentjen, Frank
Nagtegaal, Iris D.
Simmer, Femke
Source :
Te Groen , M , Derikx , L A A P , van Lierop , L , Ylstra , B , Hoentjen , F , Nagtegaal , I D & Simmer , F 2023 , ' Clonal Patterns Between Pouch Neoplasia and Prior Colorectal Neoplasia in Inflammatory Bowel Disease Patients : An Exploratory Cohort Study ' , Inflammatory Bowel Diseases , vol. 29 , no. 8 , pp. 1347-1351 .
Publication Year :
2023

Abstract

Prior colorectal neoplasia is the strongest predictor of pouch neoplasia in inflammatory bowel disease, but the underlying mechanism is unknown. We observed clonality between colorectal and pouch neoplasia in 30% of patients, indicating that most pouch neoplasia develops clonally independent from prior colorectal lesions.

Details

Database :
OAIster
Journal :
Te Groen , M , Derikx , L A A P , van Lierop , L , Ylstra , B , Hoentjen , F , Nagtegaal , I D & Simmer , F 2023 , ' Clonal Patterns Between Pouch Neoplasia and Prior Colorectal Neoplasia in Inflammatory Bowel Disease Patients : An Exploratory Cohort Study ' , Inflammatory Bowel Diseases , vol. 29 , no. 8 , pp. 1347-1351 .
Notes :
application/pdf, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1398451636
Document Type :
Electronic Resource