Back to Search Start Over

Role of microRNA-122 in hepatic lipid metabolism of the weanling female rat offspring exposed to prenatal and postnatal caloric restriction.

Authors :
Dai, Yun
Dai, Yun
Ghosh, Shubhamoy
Shin, Bo-Chul
Devaskar, Sherin U
Dai, Yun
Dai, Yun
Ghosh, Shubhamoy
Shin, Bo-Chul
Devaskar, Sherin U
Publication Year :
2019

Abstract

We examined the role of hepatocyte micro-RNA-122 and hypothalamic neuropeptides, in weanling (21d) female rats exposed to calorie restriction induced growth restriction either prenatally (IUGR), postnatally (PNGR) or both (IPGR) vs. ad lib fed controls (CON). IUGR were hyperinsulinemic, hyperleptinemic and dyslipidemic with high circulating miR-122. In contrast, PNGR and IPGR displayed insufficient glucose, insulin and leptin amidst high ketones with a dichotomy in circulating miR-122 of PNGR

Details

Database :
OAIster
Notes :
application/pdf
Publication Type :
Electronic Resource
Accession number :
edsoai.on1391599011
Document Type :
Electronic Resource