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Brain stem encephalitis is a rare complication of COVID-19
- Source :
- Shamier , M C , Crijnen , Y S , Bogers , S , IJpelaar , J W , de Vries , J M , van der Jagt , M , Spoor , J K H , von der Thüsen , J H , Schreurs , M W J , GeurtsvanKessel , C H & Titulaer , M J 2023 , ' Brain stem encephalitis is a rare complication of COVID-19 ' , Journal of Neuroimmunology , vol. 374 , 578007 .
- Publication Year :
- 2023
-
Abstract
- Here, we describe the clinical phenotype of SARS-CoV-2-related CNS disease and evaluate the SARS-CoV-2 antibody index as a tool to differentiate between a direct (viral) and indirect etiology. Out of >4000 hospitalized patients with COVID-19, we included 13 patients with neurological symptoms with suspicion of neuroinflammation. On clinical grounds, eight were classified as having a possible/probable relationship between neurological symptoms and COVID-19. A clinically distinctive phenotype of brainstem and cerebellar symptoms was seen in 6/8 patients. As we found a positive SARS-CoV-2 antibody index in 3/5 patients, indicating specific intrathecal SARS-CoV-2 IgG production, a direct link with SARS-CoV-2 is likely.
Details
- Database :
- OAIster
- Journal :
- Shamier , M C , Crijnen , Y S , Bogers , S , IJpelaar , J W , de Vries , J M , van der Jagt , M , Spoor , J K H , von der Thüsen , J H , Schreurs , M W J , GeurtsvanKessel , C H & Titulaer , M J 2023 , ' Brain stem encephalitis is a rare complication of COVID-19 ' , Journal of Neuroimmunology , vol. 374 , 578007 .
- Notes :
- application/pdf, English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1376784038
- Document Type :
- Electronic Resource