Adipose derived stem cells and their importance in surgical treatment of cleft lip and palate: Adipose drived stem cells

Aim: Facial fat grafting has undergone noteworthy changes over time. Many different techniques have been followed by trying to advance the quality of the lipoaspirate and the survival of the fat graft after implantation. Methodology: The current review emphasizes the role of Adipose derived stem cells in autologous fat grafting in the maxillofacial region. Results: Fat transfer techniques have demonstrated utility in the correction of a host of deformities through soft tissue augmentation. More recently, there is evidence that fat grafts harbor stem cells, Adipose derived stem cells and that these pluripotent cells produce factors beneficial for wound healing and regeneration. This autogenous tissue may also improve scar caliber and minimize scar burden. Many researches have recently revealed that infant-derived Adipose derived stem cells are more biologically robust than those obtained from adult tissue. Conclusion: It may be inferred from the above study that fat grafting may appear to enhance the esthetic outcome in the local anatomical region of the cleft.