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Very low prevalence of ultrasound-detected tenosynovial abnormalities in healthy subjects throughout the age range: OMERACT ultrasound minimal disease study.

Authors :
UCL - SSS/IREC/RUMA - Pôle de Pathologies rhumatismales
UCL - (SLuc) Service de rhumatologie
Trickey, Jeanette
Sahbudin, Ilfita
Ammitzbøll-Danielsen, Mads
Azzolin, Irene
Borst, Carina
Bortoluzzi, Alessandra
Bruyn, George Aw
Carron, Philippe
Ciurtin, Coziana
Filippou, Georgios
Fliciński, Jacek
Fodor, Daniela
Gouze, Hélène
Gutierrez, Marwin
Hammer, Hilde Berner
Hauge, Ellen-Margrethe
Iagnocco, Annamaria
Ikeda, Kei
Karalilova, Rositsa
Keen, Helen Isobel
Kortekaas, Marion
La Paglia, Giuliana
Leon, Gustavo
Mandl, Peter
Maruseac, Mihaela
Milchert, Marcin
Mortada, Mohamed Atia
Naredo, Esperanza
Ohrndorf, Sarah
Pineda, Carlos
Rasch, Mads Nyhuus Bendix
Reátegui-Sokolova, Cristina
Sakellariou, Garifallia
Serban, Teodora
Sifuentes-Cantú, Cesar A
Stoenoiu, Maria S
Suzuki, Takeshi
Terslev, Lene
Tinazzi, Ilaria
Vreju, Florentin Ananu
Wittoek, Ruth
D'Agostino, Maria-Antonietta
Filer, Andrew
UCL - SSS/IREC/RUMA - Pôle de Pathologies rhumatismales
UCL - (SLuc) Service de rhumatologie
Trickey, Jeanette
Sahbudin, Ilfita
Ammitzbøll-Danielsen, Mads
Azzolin, Irene
Borst, Carina
Bortoluzzi, Alessandra
Bruyn, George Aw
Carron, Philippe
Ciurtin, Coziana
Filippou, Georgios
Fliciński, Jacek
Fodor, Daniela
Gouze, Hélène
Gutierrez, Marwin
Hammer, Hilde Berner
Hauge, Ellen-Margrethe
Iagnocco, Annamaria
Ikeda, Kei
Karalilova, Rositsa
Keen, Helen Isobel
Kortekaas, Marion
La Paglia, Giuliana
Leon, Gustavo
Mandl, Peter
Maruseac, Mihaela
Milchert, Marcin
Mortada, Mohamed Atia
Naredo, Esperanza
Ohrndorf, Sarah
Pineda, Carlos
Rasch, Mads Nyhuus Bendix
Reátegui-Sokolova, Cristina
Sakellariou, Garifallia
Serban, Teodora
Sifuentes-Cantú, Cesar A
Stoenoiu, Maria S
Suzuki, Takeshi
Terslev, Lene
Tinazzi, Ilaria
Vreju, Florentin Ananu
Wittoek, Ruth
D'Agostino, Maria-Antonietta
Filer, Andrew
Source :
Annals of the rheumatic diseases, Vol. 81, no.2, p. 232-236 (2022)
Publication Year :
2022

Abstract

This study aimed to determine the prevalence of ultrasound-detected tendon abnormalities in healthy subjects (HS) across the age range. Adult HS (age 18-80 years) were recruited in 23 international Outcome Measures in Rheumatology ultrasound centres and were clinically assessed to exclude inflammatory diseases or overt osteoarthritis before undergoing a bilateral ultrasound examination of digit flexors (DFs) 1-5 and extensor carpi ulnaris (ECU) tendons to detect the presence of tenosynovial hypertrophy (TSH), tenosynovial power Doppler (TPD) and tenosynovial effusion (TEF), usually considered ultrasound signs of inflammatory diseases. A comparison cohort of patients with rheumatoid arthritis (RA) was taken from the Birmingham Early Arthritis early arthritis inception cohort. 939 HS and 144 patients with RA were included. The majority of HS (85%) had grade 0 for TSH, TPD and TEF in all DF and ECU tendons examined. There was a statistically significant difference in the proportion of TSH and TPD involvement between HS and subjects with RA (HS vs RA p<0.001). In HS, there was no difference in the presence of ultrasound abnormalities between age groups. Ultrasound-detected TSH and TPD abnormalities are rare in HS and can be regarded as markers of active inflammatory disease, especially in newly presenting RA.

Details

Database :
OAIster
Journal :
Annals of the rheumatic diseases, Vol. 81, no.2, p. 232-236 (2022)
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1372953519
Document Type :
Electronic Resource