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AUY922 effectively overcomes MET- And AXL-mediated resistance to EGFR-TKI in lung cancer cells

Authors :
Bivona, Trever
Bivona, Trever
Choi, YJ
Kim, SY
So, KS
Baek, IJ
Kim, WS
Choi, SH
Lee, JC
Bivona, TG
Rho, JK
Choi, CM
Bivona, Trever
Bivona, Trever
Choi, YJ
Kim, SY
So, KS
Baek, IJ
Kim, WS
Choi, SH
Lee, JC
Bivona, TG
Rho, JK
Choi, CM
Publication Year :
2015

Abstract

© 2015, public library of science. All rights reserved.The activation of bypass signals, such as MET and AXL, has been identified as a possible mechanism of EGFR-TKI resistance. Because various oncoproteins depend on HSP90 for maturation and stability, we

Details

Database :
OAIster
Publication Type :
Electronic Resource
Accession number :
edsoai.on1367639380
Document Type :
Electronic Resource