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Factors Associated with Unfavourable Treatment Outcomes in Patients with Tuberculosis: A 16-Year Cohort Study (2005-2020), Republic of Karakalpakstan, Uzbekistan
- Source :
- International Journal of Environmental Research and Public Health; 1660-4601; 23; 18; 12827; ~International Journal of Environmental Research and Public Health~~~~~1660-4601~23~18~~12827
- Publication Year :
- 2021
-
Abstract
- Contains fulltext : 242604.pdf (Publisher’s version ) (Open Access)<br />Tuberculosis (TB) remains a public health burden in the Republic of Karakalpakstan, Uzbekistan. This region-wide retrospective cohort study reports the treatment outcomes of patients registered in the TB electronic register and treated with first-line drugs in the TB Programme of the Republic of Karakalpakstan from 2005-2020 and factors associated with unfavourable outcomes. Among 35,122 registered patients, 24,394 (69%) patients were adults, 2339 (7%) were children, 18,032 (51%) were male and 19,774 (68%) lived in rural areas. Of these patients, 29,130 (83%) had pulmonary TB and 7497 (>22%) had been previously treated. There were 7440 (21%) patients who had unfavourable treatment outcomes. Factors associated with unfavourable treatment outcomes included: increasing age, living in certain parts of the republic, disability, pensioner status, unemployment, being HIV-positive, having pulmonary TB, and receiving category II treatment. Factors associated with death included: being adult and elderly, living in certain parts of the republic, having a disability, pensioner status, being HIV-positive, and receiving category II treatment. Factors associated with failure included: being adolescent, female, having pulmonary TB. Factors associated with loss to follow-up included: being male, disability, pensioner status, unemployment, receiving category II treatment. In summary, there are sub-groups of patients who need special attention in order to decrease unfavourable treatment outcomes.
Details
- Database :
- OAIster
- Journal :
- International Journal of Environmental Research and Public Health; 1660-4601; 23; 18; 12827; ~International Journal of Environmental Research and Public Health~~~~~1660-4601~23~18~~12827
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1366864166
- Document Type :
- Electronic Resource